Candidate Compounds Covid19

Version vom 7. Juli 2020, 11:57 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

current items will be put into the subsections.

• reviews on covid drug development
• scouting ideas

• Patients on biologicals
• HMGB1, RAGE
• pre-Interleukin 6
• post-Interleukin 6
• pre-TNFalpha
• post-TNFalpha
• pre-Interleukin 17
• post-Interleukin 17
• pre-Interleukin 1
• post-Interleukin 1
• Inflammasome colchicine
• Methotrexate
• other anti-inflammatory
• NK-kappaB
• STAT 3
• JAK Janus Kinase
• Corticosteroids
• Cytokine absorbers
• Target Complement system
• Target Extracellular traps
• TGF beta
• Anticoagulant in covid19
• Antioxidants
• Stem cells
• MDSC cells
• Interferons

• other single compounds
• Retargeted single compounds
• Hydroxychloroquine
• Target ACE2, Spike protein
• Target TMPRSS2, Spike protein any other covid targed herein
• other antiviral compounds
• AV Remdesivir
• AV Lopinavir
• AV Ivermectin
• AV Arabidol
• AV Favipiravir

• Vitamin D
• Anorganic nutrients Magnesium
• Anorganic nutrients Selenium
• Anorganic nutrients Zinc
• Nutrition, general
• Exercise, Vibration

• Traditional Chinese Medicine
• Natural compounds

• Statins
• Antidiabetic compounds, any
• RSP - On RAS drugs

• Reconvalescent blood products, Passive vaccine
• Plasmapheresis

• Immunodeviation e.g. by adjuvants or other vaccinations
• Radiation therapy
• Phototherapy
• Active vaccine

• Treatment other concepts

-rest-

009

32535032 2020. Vitamin D Receptor stimulation to reduce Acute Respiratory Distress Syndrome (ARDS) in patients with Coronavirus SARS-CoV-2 infections: Revised Ms SBMB 2020_166.

32423449 2020. Rationale for the clinical use of adipose-derived mesenchymal stem cells for COVID-19 patients.

32405423 2020. Minimum costs to manufacture new treatments for COVID-19.
32405422 2020. Review of safety and minimum pricing of nitazoxanide for potential treatment of COVID-19.
32405421 2020. A review of the safety of favipiravir - a potential treatment in the COVID-19 pandemic?
32401274 2020. SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults.

32501511 2020. Simulated Assessment of Pharmacokinetically Guided Dosing for Investigational Treatments of Pediatric Patients With Coronavirus Disease 2019.
32530438 2020. New (re)Purpose for an old drug: purinergic receptor blockade may extinguish the COVID-19 thrombo-inflammatory firestorm.
32459647 2020. Intra-Rater and Inter-Rater Reliability of Tongue Coating Diagnosis in Traditional Chinese Medicine Using Smartphones: Quasi-Delphi Study.
32384188 2020. Parenteral Fish-Oil Emulsions in Critically Ill COVID-19 Emulsions.
32401715 2020. Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial.
32401712 2020. Interferon beta-1b for COVID-19.
32410758 2020. Consider pregnancy in COVID-19 therapeutic drug and vaccine trials.

32464115 2020. Caution against corticosteroid-based COVID-19 treatment.
32445630 2020. Vitamin-D and COVID-19: do deficient risk a poorer outcome?
32501454 2020. Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study.
32518419 2020. The Janus kinase 1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation.
32528040 2020. Holding CoVID in check through JAK? The MPN-approved compound ruxolitinib as a potential strategy to treat SARS-CoV-2 induced systemic hyperinflammation.

32535080 2020. Virtual screening, ADME/Tox predictions and the drug repurposing concept for future use of old drugs against the COVID-19.
32497632 2020. Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements.
32454157 2020. Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19.
32450171 2020. Coronaviruses pandemics: Can neutralizing antibodies help?
32450166 2020. Unravelling lead antiviral phytochemicals for the inhibition of SARS-CoV-2 M(pro) enzyme through in silico approach.
32422305 2020. Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment.

32478465 2020. First case of drug-induced liver injury associated with the use of tocilizumab in a patient with COVID-19.
32532461 2020. Eficacia de los pulsos de corticoides en pacientes con sindrome de liberacion de citocinas inducido por infeccion por SARS-CoV-2.

32416415 2020. Etoposide-based therapy for severe forms of COVID-19.
32516655 2020. Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent.
32504923 2020. N-Acetylcysteine: A potential therapeutic agent for SARS-CoV-2.
32485316 2020. Pentoxifylline and complicated COVID-19: A pathophysiologically based treatment proposal.
32498007 2020. Immunopharmacological management of COVID-19: Potential therapeutic role of valproic acid.
32492562 2020. The association between obesity and poor outcome after COVID-19 indicates a potential therapeutic role for montelukast.
32480250 2020. Protective effects of vaccinations and endemic infections on COVID-19: A hypothesis.
32464491 2020. Selenium supplementation in the prevention of coronavirus infections (COVID-19).
32526511 2020. A potential role for cyclophosphamide in the mitigation of acute respiratory distress syndrome among patients with SARS-CoV-2.
32473509 2020. Zinc Iodide in combination with Dimethyl Sulfoxide for treatment of SARS-CoV-2 and other viral infections.
32470789 2020. Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists.
32534175 2020. Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials.
32464494 2020. Homocysteine as a potential predictor of cardiovascular risk in patients with COVID-19.
32526507 2020. Use of hydroxychloroquine and interferon alpha-2b for the prophylaxis of COVID-19.
32464493 2020. Hypoxia inducible factor-1 protects against COVID-19: A hypothesis.
32464492 2020. Can moderate intensity aerobic exercise be an effective and valuable therapy in preventing and controlling the pandemic of COVID-19?
32460208 2020. Sodium chromo-glycate and palmitoylethanolamide: A possible strategy to treat mast cell-induced lung inflammation in COVID-19.
32425307 2020. Mesenchymal Stem Cells -Bridge Catalyst Between Innte And Adaptive Immunity In Covid 19.
32425306 2020. Protective potential of Expectorants against COVID-19.
32416408 2020. As a potential treatment of COVID-19: Montelukast.
32413699 2020. Lithium chloride combination with rapamycin for the treatment of COVID-19 pneumonia.
32531538 2020. Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection?
32531537 2020. RAGE receptor: May be a potential inflammatory mediator for SARS-COV-2 infection?
32516733 2020. B-cell engineering: A promising approach towards vaccine development for COVID-19.
32535456 2020. Natural RNA dependent RNA polymerase inhibitors: Molecular docking studies of some biologically active alkaloids of Argemone mexicana.
32534337 2020. Diacerein: A potential multi-target therapeutic drug for COVID-19.
32505075 2020. Fighting against frailty and sarcopenia - As well as COVID-19?
32505072 2020. COVID-19 and picotechnology: Potential opportunities.
32505069 2020. Hydrogen peroxide and viral infections: A literature review with research hypothesis definition in relation to the current covid-19 pandemic.
32400020 2020. COVID-19 and implications for thiopurine use.
32395220 2020. SARS-CoV-2 (COVID-19) and Chronic Myeloid Leukemia (CML): a Case Report and Review of ABL Kinase Involvement in Viral Infection.
32470350 2020. Commentary: Myths and facts on vitamin D amidst the COVID-19 pandemic.
32497535 2020. Commentary: Phosphodiesterase 4 inhibitors as potential adjunct treatment targeting the cytokine storm in COVID-19.
32418885 2020. Commentary: Could iron chelators prove to be useful as an adjunct to COVID-19 Treatment Regimens?
32473390 2020. A review of South Indian medicinal plant has the ability to combat against deadly viruses along with COVID-19?

32445881 2020. Arbidol/IFN-alpha2b therapy for patients with corona virus disease 2019: a retrospective multicenter cohort study.
32442649 2020. Plant Solutions for the COVID-19 Pandemic and Beyond: Historical Reflections and Future Perspectives.

32404512 2020. Can Unconventional Immunomodulatory Agents Help Alleviate COVID-19 Symptoms and Severity?

32445439 2020. Surgery Scheduling in a Crisis.

32529545 2020. Natural Products as Potential Leads Against Coronaviruses: Could They be Encouraging Structural Models Against SARS-CoV-2?

32533109 2020. Passive antibody therapy in COVID-19.
32393823 2020. BCG-induced trained immunity: can it offer protection against COVID-19?
32462282 2020. Ivermectin, antiviral properties and COVID-19: a possible new mechanism of action.
32451597 2020. Vitamin D can prevent COVID-19 infection-induced multiple organ damage.
32430617 2020. A comprehensive review on drug repositioning against coronavirus disease 2019 (COVID19).

32342609 2020. The Use of Non-invasive Vagus Nerve Stimulation to Treat Respiratory Symptoms Associated With COVID-19: A Theoretical Hypothesis and Early Clinical Experience. {{tp|p=32383751|t=2020. Beyond Smoking Cessation: Investigating Medicinal Nicotine to Prevent and Treat COVID-19.|pdf=|usr=009
32521760 2020. Diet Supplementation, Probiotics, and Nutraceuticals in SARS-CoV-2 Infection: A Scoping Review.
32532069 2020. Can Probiotics and Diet Promote Beneficial Immune Modulation and Purine Control in Coronavirus Infection?
32519174 2020. What can we learn about corticosteroid therapy as a treatment for COVID-19?
32528623 2020. COVID-19 infection and oxidative stress: an under-explored approach for prevention and treatment?

32431755 2020. The novel immunomodulatory biologic LMWF5A for pharmacological attenuation of the "cytokine storm" in COVID-19 patients: a hypothesis.
32451736 2020. Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19.
32454586 2020. Demand for potentially hazardous COVID-19 treatments.
32454583 2020. ICER releases pricing models for potential COVID-19 treatments.
32473310 2020. Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system.

32445955 2020. Letter to the Editor in response to the article "Could IL-17 represent a new therapeutic target for the treatment and/or management of COVID-19-related respiratory syndrome?"

32430287 2020. Rho kinase inhibitors for SARS-CoV-2 induced acute respiratory distress syndrome: Support from Bartter's and Gitelman's syndrome patients.

32405226 2020. Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases.

32502640 2020. Optimising effectiveness of health care and value of clinical trials in the COVID -19 outbreak.
32470470 2020. Cathepsin L-selective inhibitors: A potentially promising treatment for COVID-19 patients.
32442437 2020. The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges.
32437972 2020. COVID-19: Beyond the virus. The use of Photodynamic Therapy for the Treatment of Infections in the Respiratory Tract.

32493609 2020. SGLT-2 inhibitors for COVID-19 - A miracle waiting to happen or just another beat around the bush?
32519302 2020. Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics.
32415971 2020. Use of statins in patients with COVID-19.
32415962 2020. Reply: Use of statins in patients with COVID-19.
32522574 2020. Coping with hypoxemia: Could erythropoietin (EPO) be an adjuvant treatment of COVID-19?
32514354 2020. High-dose, short-term corticosteroids for ARDS caused by COVID-19: a case series.

32426002 2020. Opciones Terapeuticas En El Manejo De Covid-19 Grave: Una Perspectiva De Reumatologia.
32426001 2020. Colchicina: una herramienta terapeutica potencial frente a COVID-19. Experiencia en 5 pacientes.

32414660 2020. Exercising in times of COVID-19: what do experts recommend doing within four walls?
32491104 2020. Clinical characteristics and therapeutic procedure for a critical case of novel coronavirus pneumonia treated with glucocorticoids and non-invasive ventilator treatment.

32404477 2020. A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2.

32467561 2020. Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2.
32460839 2020. Intravenous infusion of human umbilical cord Wharton's jelly-derived mesenchymal stem cells as a potential treatment for patients with COVID-19 pneumonia.
32526079 2020. Current status of mesenchymal stem cell therapy for immune/inflammatory lung disorders: Gleaning insights for possible use in COVID-19.
32412544 2020. In silico fight against novel coronavirus by finding chromone derivatives as inhibitor of coronavirus main proteases enzyme.

32436460 2020. TNFalpha inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis.
32436445 2020. Potential specific therapies in COVID-19.
32483428 2020. Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients.
32487513 2020. Convalescent (immune) plasma treatment in a myelodysplastic COVID-19 patient with disseminated tuberculosis.
32532691 2020. Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19.
32467007 2020. Successful treatment of a centenarian with coronavirus disease 2019 (COVID-19) using convalescent plasma.
32425645 2020. Use of convalescent plasma in COVID-19 patients in China.
32406985 2020. Interleukin-6 receptor antagonist therapy to treat SARS-CoV-2 driven inflammatory syndrome in a kidney transplant recipient.

32471655 2020. Overwhelming COVID-19 Clinical Trials: Call for Prospective Meta-Analyses.
32454984 2020. Battling COVID-19: using old weapons for a new enemy.
32376108 2020. Archetype analysis of older adult immunization decision-making and implementation in 34 countries.
32236815 2020. Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection.

32530808 2020. Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series.
32531236 2020. Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China.
32532094 2020. The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
32532085 2020. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19).
32426090 2020. COVID-19, asthma, and biologic therapies: What we need to know.
32417996 2020. BCG versus COVID-19: impact on urology.
32514854 2020. Biologikatherapie nach COVID-19-Infektion : Keine Reaktivierung einer COVID-19-Infektion bei positivem Antikorperstatus SARS-CoV-2 unter Biologikatherapie.

32555446 2020. Overview of therapeutic drug research for COVID-19 in China.

32574894 2020. Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic.
32583087 2020. IL-1R blockade is not effective in patients with hematological malignancies and severe SARS-CoV-2 infection.

32543882 2020. Promoting Better Clinical Trials and Drug Information as Public Health Interventions for the COVID-19 Emergency in Italy.
32571831 2020. IMPACT OF GLUCOCORTICOID TREATMENT IN SARS-COV-2 INFECTION MORTALITY: A RETROSPECTIVE CONTROLLED COHORT STUDY.
32575554 2020. Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections.
32562705 2020. A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19.
32557214 2020. Potential Role of Anti-interleukin (IL)-6 Drugs in the Treatment of COVID-19: Rationale, Clinical Evidence and Risks.
32586336 2020. A prospect on the use of antiviral drugs to control local outbreaks of COVID-19.

32572174 2020. Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy.
32546835 2020. Immune checkpoint blockade: releasing the breaks or a protective barrier to COVID-19 severe acute respiratory syndrome?

32492407 2020. Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19.
32546764 2020. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis.
32541865 2020. Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
32588163 2020. Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19.
32585295 2020. Inhibition of cytokine signaling by ruxolitinib and implications for COVID-19 treatment.
32564213 2020. The rationale for the use of colchicine in COVID-19: comments on the letter by Cumhur Cure M et al.
32564212 2020. Comment on "Colchicine may not be effective in COVID-19 infection; it may even be harmful?"
32556936 2020. Colchicine as a possible therapeutic option in COVID-19 infection.
32548723 2020. Impact of anti-rheumatic drugs and steroids on clinical course and prognosis of COVID-19.

32593060 2020. Helping doctors hasten COVID-19 treatment: Towards a rescue framework for the transfusion of best convalescent plasma to the most critical patients based on biological requirements via ml and novel MCDM methods.
32558354 2020. Timing of antiviral treatment initiation is critical to reduce SARS-CoV-2 viral load.
32552848 2020. Compassionate use of others' immunity - understanding gut microbiome in Covid-19.
32552832 2020. First do no harm-beware the risk of therapeutic plasma exchange in severe COVID-19.
32572376 2020. Literature-based review of the drugs used for the treatment of COVID-19.
32578027 2020. A Rapid Advice Guideline for the Prevention of Novel Coronavirus Through Nutritional Intervention.
32562159 2020. The clinical value of two combination regimens in the Management of Patients Suffering from Covid-19 pneumonia: a single centered, retrospective, observational study.
32542964 2020. Treatment of Covid19 - Repurposing drugs commonly used in dermatology.

32537890 2020. Observation and consideration on using of JAKi in clinical trials in times of COVID-19.
32592841 2020. A proposed mechanism for the possible therapeutic potential of Metformin in COVID-19.
32581194 2020. Targeting lymphocyte Kv1.3-channels to suppress cytokine storm in severe COVID-19: Can it be a novel therapeutic strategy?
32554953 2020. Can mesenchymal stem cell therapy be the interim management of COVID-19?

32574699 2020. Discovering small-molecule therapeutics against SARS-CoV-2.
32574697 2020. Current and future therapeutical approaches for COVID-19.
32569833 2020. Exportin 1 inhibition as antiviral therapy.
32546018 2020. The broad-spectrum antiviral recommendations for drug discovery against COVID-19.

32592145 2020. Identification of a Potential Peptide Inhibitor of SARS-CoV-2 Targeting its Entry into the Host Cells.
32574958 2020. Targeting innate immunity by blocking CD14: Novel approach to control inflammation and organ dysfunction in COVID-19 illness.
32573433 2020. Antibodies to SARS-CoV-2 and their potential for therapeutic passive immunization.
32569446 2020. Can artificial intelligence identify effective COVID-19 therapies?
32579067 2020. In Vivo Expressed Biologics for Infectious Disease Prophylaxis: Rapid Delivery of DNA-Based Antiviral Antibodies.
32562594 2020. Pregnant Women in Trials of COVID-19: A Critical Time to Consider Ethical Frameworks of Inclusion in Clinical Trials.
32561291 2020. Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management?
32554535 2020. Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors (nAChR) and beyond.
32589055 2020. Vesicular drug-delivery systems as theranostics in COVID-19.
32564623 2020. Tackling SARS-CoV-2: proposed targets and repurposed drugs.
32578073 2020. Elderly at time of COronaVIrus disease 2019 (COVID-19): possible role of immunosenescence and malnutrition.
32577840 2020. Introduction: microbes, networks, knowledge-disease ecology and emerging infectious diseases in time of COVID-19.
32544304 2020. Antiretroviral HIV drugs in COVID-19 research: promises and risks. An opinion piece.
32591003 2020. Application of CRISPR/Cas9 to human-induced pluripotent stem cells: from gene editing to drug discovery.
32546029 2020. Case report: use of lenzilumab and tocilizumab for the treatment of coronavirus disease 2019.

32588335 2020. COVID-19, equipoise and observational studies: a reminder of forgotten issues.
32557206 2020. Rapid radiological improvement of COVID-19 pneumonia after treatment with tocilizumab.
32582401 2020. Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases.
32582400 2020. Steps towards COVID-19 suppression.

32585284 2020. Therapeutic Plasma Exchange in Adults with Severe COVID-19 Infection.
32579907 2020. Paromomycin: a potential dual targeted drug effectively inhibits both Spike (S1) and Main Protease of COVID-19.
32585194 2020. Convalescent plasma therapy in the treatment of COVID-19: Some considerations: Correspondence.
32592113 2020. Potential role of incretins in diabetes and COVID-19 infection: a hypothesis worth exploring.

32588377 2020. Corticosteroids in diabetes patients infected with COVID-19.

32578215 2020. Could Anti-Tubercular Vaccination Protect Against Covid-19 Infection?
32552021 2020. From "Infodemics" to Health Promotion: A Novel Framework for the Role of Social Media in Public Health.
32579022 2020. Lung Mechanics in COVID-19 Resemble RDS not ARDS: Could Surfactant be a Treatment?
32579020 2020. Treatment of COVID-19 by Inhaled NO to Reduce Shunt?
32551560 2020. Discovery of Aptamers Targeting Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein.
32585180 2020. Use of inhaled corticosteroids in asthma and COVID-19 : Keep calm and carry on.

32561608 2020. Role of antimalarials in COVID-19: observational data from a cohort of rheumatic patients.
32574109 2020. Structural Basis of the SARS-CoV-2/SARS-CoV Receptor Binding and Small-Molecule Blockers as Potential Therapeutics.

32551883 2020. COVID-19 and the Drug Repurposing Tsunami.
32573724 2020. Improved Clinical Symptoms and Mortality on Severe/Critical COVID-19 Patients Utilizing Convalescent Plasma Transfusion.
32559767 2020. Use of Convalescent Plasma in Hospitalized Patients with Covid-19 - Case Series.
32576548 2020. Covid-19: Demand for dexamethasone surges as RECOVERY trial publishes preprint.
32546467 2020. Covid-19: Low dose steroid cuts death in ventilated patients by one third, trial finds.

32548616 2020. Corticosteroids in patients with COVID-19: what about the control group?

32584431 2020. Colchicin Treatment of Covid-19 Presenting With Cutaneous Rash and Myopericarditis.
32562762 2020. SGLT2 inhibition during the COVID-19 epidemic: Friend or foe?

32588937 2020. Adjustments in analyses of vitamin D status, allowing for vitamin D determinants, for Covid-19 risks.
32559771 2020. The Battle against COVID 19 Pandemic: What we Need to Know Before we "Test Fire" Ivermectin.
32588530 2020. RNA to the rescue: RNA is one of the most promising targets for drug development given its wide variety of uses.
32567239 2020. Advantages of Using Lotteries to Select Participants for High-Demand Covid-19 Treatment Trials.

32574081 2020. Can nanotechnology help in the fight against COVID-19?
32552044 2020. Repurposing minocycline for COVID-19 management: mechanisms, opportunities, and challenges.
32576053 2020. Opioids/cannabinoids as a potential therapeutic approach in COVID-19 patients.
32553760 2020. TNFalpha-antagonist use and mucosal inflammation are associated with increased intestinal expression of SARS-CoV-2 host protease TMPRSS2 in patients with inflammatory bowel disease.
32553757 2020. Aminosalicylates and COVID-19: Facts or Coincidences?
32554621 2020. Infliximab for severe ulcerative colitis and subsequent SARS-CoV-2 pneumonia: a stone for two birds.

32557541 2020. A Comprehensive Review on Tocilizumab in COVID-19 Acute Respiratory Distress Syndrome.
32561274 2020. In silico prediction of potential inhibitors for the Main protease of SARS-CoV-2 using molecular docking and dynamics simulation based drug-repurposing.

32539378 2020. Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities.
32562701 2020. Apelin-potential therapy for COVID-19?

32543196 2020. Repositioning of 8565 Existing Drugs for COVID-19.
32586380 2020. Advanced bioinformatics rapidly identifies existing therapeutics for patients with coronavirus disease-2019 (COVID-19).

32589146 2020. Statistical Issues and Lessons Learned from COVID-19 Clinical Trials with Lopinavir-Ritonavir and Remdesivir.

32553190 2020. Appropriate selection of convalescent plasma donors for COVID-19.
32555367 2020. Regional BCG vaccination policy in former East- and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia.
32555296 2020. Ruxolitinib for the treatment of SARS-CoV-2 induced acute respiratory distress syndrome (ARDS).

32561657 2020. Could an Unrelated Live Attenuated Vaccine Serve as a Preventive Measure To Dampen Septic Inflammation Associated with COVID-19 Infection?
32590324 2020. Targeting adenosinergic pathway and adenosine A2A receptor signaling for the treatment of COVID-19: A hypothesis.
32575019 2020. Pirfenidone: A novel hypothetical treatment for COVID-19.
32558640 2020. Cibler la protease majeure du SARS-CoV-2 pour fabriquer un medicament efficace contre ce coronavirus.
32590819 2020. Critically ill patients with COVID-19 with ECMO and artificial liver plasma exchange: A retrospective study.
32574789 2020. Predictive factors of mortality in patients treated with tocilizumab for acute respiratory distress syndrome related to coronavirus disease 2019 (COVID-19).
32570850 2020. Microbiota Modulating Nutritional Approaches to Countering the Effects of Viral Respiratory Infections Including SARS-CoV-2 through Promoting Metabolic and Immune Fitness with Probiotics and Plant Bioactives.
32546125 2020. Erythropoietin as candidate for supportive treatment of severe COVID-19.
32560203 2020. Quinoxaline Derivatives as Antiviral Agents: A Systematic Review.

32557405 2020. Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences.
32576980 2020. GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches.

32587103 2020. Extending rituximab dosing intervals in patients with MS during the COVID-19 pandemic and beyond?
32590117 2020. Nitric oxide dosed in short bursts at high concentrations may protect against Covid 19.
32405159 2020. May statins and PCSK9 inhibitors be protective from COVID-19 in familial hypercholesterolemia subjects?
32564413 2020. Is 0.5% Hydrogen Peroxide Effective against SARS-CoV-2?
32587806 2020. A potential role for Galectin-3 inhibitors in the treatment of COVID-19.

32565309 2020. Effect of combination antiviral therapy on hematological profiles in 151 adults hospitalized with severe coronavirus disease 2019.
32592716 2020. Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?
32562826 2020. Therapeutic potential of resveratrol against emerging respiratory viral infections.
32542785 2020. Baricitinib: A review of pharmacology, safety and emerging clinical experience in COVID-19.
32592911 2020. Does photodynamic therapy have potential in the treatment of COVID 19 patients?
32585401 2020. Optical theranostics and treatment dosimetry for COVID-19 lung complications: towards increasing the survival rate of vulnerable populations.
32585400 2020. Ultraviolet-based biophotonic technologies for control and prevention of COVID-19, SARS and related disorders.

32570995 2020. Short-Term Dexamethasone in Sars-CoV-2 Patients.
32552811 2020. E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR alpha7 receptor: role of nAChR alpha7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.
32558034 2020. National policies for paediatric universal BCG vaccination were associated with decreased mortality due to COVID-19.
32557955 2020. Targeting the interleukin-17 pathway to prevent acute respiratory distress syndrome associated with SARS-CoV-2 infection.
32571730 2020. Anakinra, una alternativa potencial en el tratamiento de la infeccion respiratoria grave por SARS-CoV-2 refractaria a tocilizumab.

32568026 2020. Targeting infectious Coronavirus Disease 2019 (COVID-19) with Artificial Intelligence (AI) applications: Evidence based opinion.
32593196 2020. The Another Side of COVID-19 in Alzheimer's Disease Patients: Drug-Drug Interactions.

32591771 2020. The challenging pathway towards the identification of SARS-CoV-2/COVID-19 therapeutics.

32586154 2020. Montelukast's ability to fight COVID-19 infection.
32583729 2020. Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine.
32579065 2020. Binding insight of clinically oriented drug famotidine with the identified potential target of SARS-CoV-2.

32579061 2020. Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CL(pro).

32573355 2020. Targeting SARS-COV-2 non-structural protein 16: a virtual drug repurposing study.

32571168 2020. Drug repurposing against SARS-CoV-2 using E-pharmacophore based virtual screening, molecular docking and molecular dynamics with main protease as the target.

32568618 2020. Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules as papain-like protease (PLpro) inhibitors.
32568613 2020. Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors - an in silico docking and molecular dynamics simulation study.
32568013 2020. Virtual screening and dynamics of potential inhibitors targeting RNA binding domain of nucleocapsid phosphoprotein from SARS-CoV-2.
32568012 2020. Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approach.
32567995 2020. Promising inhibitors of main protease of novel corona virus to prevent the spread of COVID-19 using docking and molecular dynamics simulation.
32567989 2020. In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2.
32567979 2020. Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
32567501 2020. Constituents of buriti oil (Mauritia flexuosa L.) like inhibitors of the SARS-Coronavirus main peptidase: an investigation by docking and molecular dynamics.
32567487 2020. nCOV-19 peptides mass fingerprinting identification, binding, and blocking of inhibitors flavonoids and anthraquinone of Moringa oleifera and hydroxychloroquine.
32568969 2020. Pharmacological development of the potential adjuvant therapeutic agents against coronavirus disease 2019.
32579707 2020. Clinical pharmacology considerations for developing small molecule treatments for COVID-19.

32584243 2020. Empiric Therapies for COVID-19: Destined to Fail by Ignoring the Lessons of History.
32591393 2020. A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.

32559419 2020. Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities.

32574572 2020. Letter to the editor: Immunomodulation by phsphodiesterase-4 inhibitor in COVID-19 patients.
32579258 2020. Antiviral activities of mycophenolic acid and IMD-0354 against SARS-CoV-2.
32578354 2020. Obesity and COVID-19: The mTOR pathway as a possible culprit.

32588453 2020. Covid-19 and Thymoquinone: Connecting the Dots.

32569363 2020. Outcomes in Patients with Severe COVID-19 Disease Treated with Tocilizumab - A Case- Controlled Study.
32584474 2020. A brief review of interplay between vitamin D and angiotensin-converting enzyme 2: Implications for a potential treatment for COVID-19.
32568376 2020. Successful treatment of severe COVID-19 with subcutaneous anakinra as a sole treatment.
32556278 2020. Real-life experience of tocilizumab use in COVID-19 patients.
32543892 2020. Development of a simple, interpretable and easily transferable QSAR model for quick screening antiviral databases in search of novel 3C-like protease (3CLpro) enzyme inhibitors against SARS-CoV diseases.
32590699 2020. ACTH 1-24 and other melanocortins for COVID-19 treatment.

32573990 2020. Heart Transplant Recipient Patient with COVID-19 Treated with Tocilizumab.
32584762 2020. [Rationales for using JAK 1/2 inhibitors in severely afflicted patients with COVID-19 pneumonia].

32542847 2020. Clinical use of Convalescent Plasma in the COVID-19 pandemic; a transfusion-focussed gap analysis with recommendations for future research priorities.

32547694 2020. Blocking Coronavirus 19 Infection via the SARS-CoV-2 Spike Protein: Initial Steps.
32547693 2020. A Role for Metal-Based Drugs in Fighting COVID-19 Infection? The Case of Auranofin.
32599103 2020. COVID-19 Fatalities, Latitude, Sunlight, and Vitamin D.

32593520 2020. Tocilizumab en nino con leucemia linfoblastica aguda y sindrome de liberacion de citoquinas asociado a COVID-19.
32566569 2020. Appealing for efficient, well organized clinical trials on COVID-19.
32566564 2020. Effectiveness and safety of glucocorticoids to treat COVID-19: a rapid review and meta-analysis.
32566562 2020. Effectiveness of intravenous immunoglobulin for children with severe COVID-19: a rapid review.
32566561 2020. Potential effectiveness and safety of antiviral agents in children with coronavirus disease 2019: a rapid review and meta-analysis.
32566896 2020. Perspectives on the development of neutralizing antibodies against SARS-CoV-2.
32545171 2020. Antimicrobial Photodynamic Therapy in the Control of COVID-19.
32545518 2020. Nrf2 Activator PB125((R)) as a Potential Therapeutic Agent against COVID-19.

32536457 2020. Should We Try SARS-CoV-2 Helicase Inhibitors for COVID-19 Therapy?
32546446 2020. Could Respiratory Fluoroquinolones, Levofloxacin and Moxifloxacin, Prove to be Beneficial as an Adjunct Treatment in COVID-19?

32594322 2020. Antiviral activity of berberine.

32593613 2020. Testing of natural products in clinical trials targeting the SARS-CoV-2 (Covid-19) Viral Spike Protein-Angiotensin Converting Enzyme-2 (ACE2) interaction.
32571182 2020. Molecular Targets in the Chemotherapy of Coronavirus Infection.
32563698 2020. Repurposing old drugs as antiviral agents for coronaviruses.

32599963 2020. Class A G Protein-Coupled Receptor Antagonist Famotidine as a Therapeutic Alternative Against SARS-CoV2: An In Silico Analysis.
32536632 2020. Potential for jaktinib hydrochloride to treat cytokine storms in patients with COVID-19.
32459144 2020. Discovery of alliin as a putative inhibitor of the main protease of SARS-CoV-2 by molecular docking.
32420049 2020. Combating COVID-19 with Mesenchymal Stem Cell therapy.
32493331 2020. An evidence mapping and analysis of registered COVID-19 clinical trials in China.

32518212 2020. Characteristics of registered clinical trials assessing treatments for COVID-19: a cross-sectional analysis.
32532425 2020. Inclusion of pregnant women in clinical trials of COVID-19 therapies: what have we learned?
32557557 2020. Harnessing resolving-based therapeutics to treat pulmonary viral infections: What can the future offer to COVID-19?

32571773 2020. Oseltamivir for coronavirus illness: post-hoc exploratory analysis of an open-label, pragmatic, randomised controlled trial in European primary care from 2016 to 2018.
32407543 2020. Reflection on passive immunotherapy in those who need most: some novel strategic arguments for obtaining safer therapeutic plasma or autologous antibodies from recovered COVID-19 infected patients.

32562276 2020. Statins: Could an old friend help the fight against COVID-19?

32397275 2020. Potential Role of Vitamin D in the Elderly to Resist COVID-19 and to Slow Progression of Parkinson's Disease.
32603679 2020. Calcineurin inhibitors revisited: A new paradigm for COVID-19?

32383125 2020. Prophylaxie post-exposition ou traitement preventif pour le syndrome respiratoire aigu severe du coronavirus 2 (SARS-CoV-2) : protocole d'etude pour une etude randomisee controlee pragmatique.
32394335 2020. Corticosteroids for critically ill COVID-19 patients with cytokine release syndrome: a limited case series.
32385712 2020. Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?
32389579 2020. Irradiation pulmonaire a faible dose pour l'orage de cytokines du COVID-19 : pourquoi pas ?
32599589 2020. Weathering the Cytokine Storm in COVID-19: Therapeutic Implications.
32426243 2020. The use of convalescent plasma therapy and remdesivir in the successful management of a critically ill obstetric patient with novel coronavirus 2019 infection: A case report.
32531248 2020. Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
32547788 2020. Off-label therapy targeting pathogenic inflammation in COVID-19.
32411313 2020. FAVORABLE ANAKINRA RESPONSES IN SEVERE COVID-19 PATIENTS WITH SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS.
32464097 2020. Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19.
32413276 2020. Identification of Human Single-Domain Antibodies against SARS-CoV-2.
32610043 2020. Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells.
32606347 2020. Distinct stem/progenitor cells proliferate to regenerate the trachea, intrapulmonary airways and alveoli in COVID-19 patients.
32409956 2020. Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia.
32606050 2020. COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach.
32599278 2020. Imatinib for COVID-19: A case report.
32603802 2020. Corticosteroid administration for viral pneumonia: COVID-19 and beyond.

32610262 2020. Role of corticosteroid in the management of COVID-19: A systemic review and a Clinician's perspective.
32601778 2020. Repurposed GI Drugs in the Treatment of COVID-19.
32593662 2020. Prevention of COVID-19 by drug repurposing: rationale from drugs prescribed for mental disorders.
32607779 2020. Can iron chelation as an adjunct treatment of COVID-19 improve the clinical outcome?
32594204 2020. The added value of pirfenidone to fight inflammation and fibrotic state induced by SARS-CoV-2 : Anti-inflammatory and anti-fibrotic therapy could solve the lung complications of the infection?

32603692 2020. Current pharmacological treatments for SARS-COV-2: A narrative review.
32598953 2020. Drug treatment of coronavirus disease 2019 (COVID-19) in China.
32598985 2020. Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections.

32594820 2020. Potential protective and therapeutic role of immune checkpoint inhibitors against viral infections and COVID-19.
32606823 2020. Potential Role of Nrf2 Activators with Dual Antiviral and Anti-Inflammatory Properties in the Management of Viral Pneumonia.

32610153 2020. COVID-19 trials in Italy: A call for simplicity, top standards and global pooling.
32574504 2020. Metabolomics to Predict Antiviral Drug Efficacy in COVID-19.
32597948 2020. Predicting Human Microbe-Drug Associations via Graph Convolutional Network with Conditional Random Field.

32593183 2020. Ruxolitinib for tocilizumab-refractory severe COVID-19 infection.
32593180 2020. Convalescent plasma for persisting Covid-19 following therapeutic lymphocyte depletion: a report of rapid recovery.

32584416 2020. Amelioration of COVID-19 related cytokine storm syndrome: Parallels to chimeric antigen receptor-T cell cytokine release syndrome.

32536693 2020. Antiviral Therapy during the Coronavirus Disease (COVID-19) Pandemic: Is It Appropriate to Treat Patients in the Absence of Significant Evidence?
32538775 2020. Combating sars-cov-2 through lipoxins, proteasome, caveolin and nuclear factor-kappab pathways in non-pregnant and pregnant populations.
32553536 2020. Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized COVID-19 Patients: Survival and Clinical Outcomes.

32573419 2020. Biomarker variation in patients successfully treated with tocilizumab for severe coronavirus disease 2019 (COVID-19): results of a multidisciplinary collaboration.
32597466 2020. Use of Baricitinib in Patients with Moderate and Severe COVID-19.
32594142 2020. COVID-19 pharmacologic treatments for children: research priorities and approach to pediatric studies.
32594120 2020. Drug-induced liver injury in a COVID-19 patient: potential interaction of remdesivir with P-glycoprotein inhibitors.
32588877 2020. High-dose but not low-dose corticosteroids potentially delay viral shedding of patients with COVID-19.
32585016 2020. THE RIGHT TIME FOR STEROIDS IN COVID-19.
32575124 2020. Compassionate Use of Tocilizumab for Treatment of SARS-CoV-2 Pneumonia.
32604407 2020. Immune modulation in COVID-19: Strategic considerations for personalized therapeutic intervention.
32602952 2020. Convalescent Plasma Therapy: Helpful Treatment of COVID-19 in a Kidney Transplant Recipient presenting with serve clinical manifestation and complex complications.
32538717 2020. Structural Biology Aids the Research of New Anti-COVID-19 Drugs.
32536564 2020. IL-15 immunotherapy is a viable strategy for COVID-19.
32540737 2020. Use of pioglitazone in people with type 2 diabetes mellitus with coronavirus disease 2019 (COVID-19): Boon or bane?

32538209 2020. Possible therapeutic agents for COVID-19: a comprehensive review.
32603486 2020. Potential drug-drug interactions associated with drugs currently proposed for COVID-19 treatment in patients receiving other treatments.

32603297 2020. Systematic Review and Meta-Analysis of the Efficacy of Nanoscale Materials Against Coronaviruses-Possible Potential Antiviral Agents for SARS-CoV-2.
32603531 2020. Febuxostat therapy in outpatients with suspected COVID-19: A clinical trial.
32603576 2020. Vitamin D and Inflammation: Potential Implications for Severity of Covid-19.

32518817 2020. Synthesis, Spectroscopic Characterizations of Novel Norcantharimides, Their ADME Properties and Docking Studies Against COVID-19 M(pr) degrees .
32572383 2020. Evaluation of the Inhibitory Activities of COVID-19 of Melaleuca cajuputi Oil Using Docking Simulation.

32548601 2020. Ventilation in the Dental Clinic: An Effective Measure to Control Droplets and Aerosols during the Coronavirus Pandemic and Beyond.
32548600 2020. Preventive and Control Measures for the Coronavirus Pandemic in Clinical Dentistry.
32242749 2020. Substituting Angiotensin-(1-7) to Prevent Lung Damage in SARS-CoV-2 Infection?
32513807 2020. What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19?
32533455 2020. Azithromycin for COVID-19: More Than Just an Antimicrobial?

32492478 2020. Treating COVID-19 with colchicine in community healthcare setting.
32544611 2020. Development of child immunity in the context of COVID-19 pandemic.
32418917 2020. Immunoglobulins in the treatment of COVID-19 infection: Proceed with caution!
32417594 2020. Supplements for COVID-19: A modifiable environmental risk.
32405269 2020. Targeting T-cell senescence and cytokine storm with rapamycin to prevent severe progression in COVID-19.
32409832 2020. SARS-CoV-2 pandemic : Time to revive the cyclophilin inhibitor alisporivir.

32537133 2020. Potential Treatments for SARS-CoV-2 Infection.

32454187 2020. Review of trials currently testing treatment and prevention of COVID-19.

32407539 2020. Clinical Trials for COVID-19: Can we Better Use the Short Window of Opportunity?

32311763 2020. Off-Label Therapies for COVID-19-Are We All In This Together?
32451729 2020. Corticosteroid treatment in severe COVID-19 pneumonia: two cases and literature review.
32394215 2020. Colchicine may not be effective in COVID-19 infection; it may even be harmful?
32388748 2020. Reply to Rheumatologists' perspective on coronavirus disease 19: is heparin the dark horse for COVID-19?

32575032 2020. Participation of more community hospitals in randomized trials of treatments for COVID-19 is needed.
32493740 2020. Efficacy and safety of antiviral treatment for COVID-19 from evidence in studies of SARSCoV-2 and other acute viral infections: a systematic review and meta-analysis.
32392494 2020. Sample sizes in COVID-19-related research.
32485652 2020. Interaction of the prototypical alpha-ketoamide inhibitor with the SARS-CoV-2 main protease active site in silico: Molecular dynamic simulations highlight the stability of the ligand-protein complex.
32537526 2020. The critical role of futility analysis in the pursuit of effective treatments for COVID-19.

32384906 2020. Use of triiodothyronine to treat critically ill COVID-19 patients: a new clinical trial.
32430057 2020. Adjuvant corticosteroid therapy for critically ill patients with COVID-19.
32414417 2020. Therapeutic plasma exchange as a routine therapy in septic shock and as an experimental treatment for COVID-19: we are not sure.
32513242 2020. Blocking mineralocorticoid receptor with spironolactone may have a wide range of therapeutic actions in severe COVID-19 disease.
32513225 2020. Neutrophil Elastase Inhibitors: A potential prophylactic treatment option for SARS-CoV-2-induced respiratory complications?
32487260 2020. Precision medicine for COVID-19: a call for better clinical trials.
32487139 2020. Cyclosporine A: a valid candidate to treat COVID-19 patients with acute respiratory failure?
32532353 2020. Interferon beta-1a for COVID-19: critical importance of the administration route.
32527304 2020. Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients.
32544802 2020. COVID 19 therapies and anti-cancer drugs: A systematic review of recent literature.
32460133 2020. Considerations for interactions of drugs used for the treatment of COVID-19 with anti-cancer treatments.
32494546 2020. Vaccines and Drug Therapeutics to Lock Down Novel Coronavirus Disease 2019 (COVID-19): A Systematic Review of Clinical Trials.

32596078 2020. Emerging Pharmaceutical Treatments of Novel COVID-19: A Review.
32577324 2020. COVID-19: A Review of Emerging Preventative Vaccines and Treatment Strategies.
32550078 2020. Heated Air Delivery by Micro-Sauna: An Experimental Treatment Prototype Concept for Coronavirus Disease 2019.
32540367 2020. A review of potential treatments to date in COVID-19 patients according to the stage of the disease.
32563554 2020. Should we unstress SARS-CoV-2 infected cells?
32565132 2020. Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies.

32563941 2020. Letter in response to the article: Vitamin D concentrations and COVID-19 infection in UK biobank (Hastie et al.).
32593491 2020. Molecular pharmacology of ciclesonide against SARS-CoV-2.

32607505 2020. COVID-19 Clinical Research.
32605278 2020. Exploring Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors for Organ Protection in COVID-19.
32605780 2020. Role of vitamin D in preventing of COVID-19 infection, progression and severity.

32605149 2020. Bioactive Indolyl Diketopiperazines from the Marine Derived Endophytic Aspergillus versicolor DY180635.
32593831 2020. Plausible role of combination of Chlorpromazine hydrochloride and Teicoplanin against COVID-19.
32604775 2020. A Comprehensive Analysis of Clinical Trials in the COVID-19 Pandemic Era.
32593740 2020. Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes.
32602074 2020. Structure-based screening of novel lichen compounds against SARS Coronavirus main protease (Mpro) as potentials inhibitors of COVID-19.
32603575 2020. Vitamin D Deficiency and ARDS after SARS-CoV-2 Infection.
32603574 2020. Vitamin D and Covid-19: A Note of Caution.
32603573 2020. Covid-19, Cocooning and Vitamin D Intake Requirements.

32551464 2020. Dexamethasone for COVID-19? Not so fast.
32597315 2020. Repurposing of FDA-approved antivirals, antibiotics, anthelmintics, antioxidants, and cell protectives against SARS-CoV-2 papain-like protease.
32608329 2020. In silico analysis and identification of promising hits against 2019 novel coronavirus 3C-like main protease enzyme.
32520770 2020. Overview of Coronavirus Disease 2019 (COVID-19): Treatment Updates and Advances.
32530870 2020. Rapid Review: Nonsteroidal Anti-inflammatory Agents and Aminosalicylates in COVID-19 Infections.
32570043 2020. Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: Results from a single Italian Centre study on tocilizumab versus standard of care.
32574020 2020. Biologics and Small Molecules in the Treatment of COVID-19.
32559285 2020. Interferon-beta 1a inhibits SARS-CoV-2 in vitro when administered after virus infection.
32603493 2020. Methylprednisolone added to tocilizumab reduces mortality in SARS-CoV-2 pneumonia: An observational study.
32583447 2020. SARS-COV-2 and biomimetics: What saves the planet will save our health.
32579254 2020. SARS-CoV-2 and SARS-CoV: Virtual Screening of Potential inhibitors targeting RNA-dependent RNA polymerase activity (NSP12).
32568411 2020. Tocilizumab's efficacy in patients with Coronavirus Disease 2019 (COVID-19) is determined by the presence of cytokine storm.
32574379 2020. A sugar-coated strategy to treat a rare neurologic disease provides a blueprint for a decoy glycan therapeutic and a potential vaccine for CoViD-19: An Editorial Highlight for "Selective inhibition of anti-MAG IgM autoantibody binding to myelin by an antigen specific glycopolymer"on https://doi.org/10.1111/jnc.15021.

32543164 2020. The comparison of the effectiveness of lincocin(R) and azitro(R) in the treatment of covid-19-associated pneumonia: A prospective study.
32608097 2020. Comparison of In Vitro Inactivation of SARS CoV-2 with Hydrogen Peroxide and Povidone-Iodine Oral Antiseptic Rinses.

32568282 2020. Emerging pharmacotherapy for COVID-19.

32515802 2020. Existing Drugs Might Treat COVID-19.
32539093 2020. Monoclonal Antibodies for Prevention and Treatment of COVID-19.
32544372 2020. Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold.

32541129 2020. Intermittent high dosage oxygen treats COVID-19 infection: the Chinese studies.
32541128 2020. Hyperbaric oxygen treatment of novel coronavirus (COVID-19) respiratory failure.
32594562 2020. Clinical trials for the prevention and treatment of COVID-19: current state of play.

32447665 2020. Mit IL-6-Inhibitor gegen COVID-19 : Corona-Pandemie.
32342366 2020. Autophagie - ein Ansatzpunkt fur ein Medikament gegen COVID-19? : Kampf gegen das Coronavirus.

32581514 2020. Characteristics of COVID-19 Clinical Trials in China Based on the Registration Data on ChiCTR and ClinicalTrials.gov.
32524646 2020. Lithium as a candidate treatment for COVID-19: Promises and pitfalls.

32425222 2020. Repurposing chlorpromazine to treat COVID-19: The reCoVery study.

32482571 2020. Consensus statement. Corticosteroid therapy in ENT in the context of the COVID-19 pandemic.
32544799 2020. Immune checkpoint inhibitors: a physiology-driven approach to the treatment of coronavirus disease 2019.

32563814 2020. Fight against novel coronavirus: A perspective of medicinal chemists.
32563813 2020. Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
32525005 2020. Effective block by pirfenidone, an antifibrotic pyridone compound (5-methyl-1-phenylpyridin-2[H-1]-one), on hyperpolarization-activated cation current: An additional but distinctive target.
32563675 2020. Investigational Therapies for the Treatment of COVID-19: Updates from Ongoing Clinical Trials.
32536989 2020. IgY - turning the page toward passive immunization in COVID-19 infection (Review).
32536988 2020. [Comment] Treatment strategies to fight the new coronavirus SARS-CoV-2: A challenge for a Rubik's Cube solver.
32537481 2020. EML webinar overview: Simulation-assisted discovery of membrane targeting nanomedicine.
32399192 2020. Recent advances in influenza vaccines.
32574317 2020. Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections.
32596244 2020. The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia.
32595653 2020. Cytokine Release Syndrome (CRS) and Nicotine in COVID-19 Patients: Trying to Calm the Storm.
32582221 2020. Could Coronavirus Disease 2019 (COVID-19) Render Natural Immunity to Re-infections? A Spotlight on the Therapeutic Pipeline.
32574274 2020. Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing?
32574273 2020. Symptomatic Protective Action of Glycyrrhizin (Licorice) in COVID-19 Infection?
32574268 2020. Fighting the Host Reaction to SARS-COv-2 in Critically Ill Patients: The Possible Contribution of Off-Label Drugs.
32574267 2020. COVID-19 and SARS Coronavirus 2: Antibodies for the Immediate Rescue and Recovery Phase.
32574263 2020. MSC Therapies for COVID-19: Importance of Patient Coagulopathy, Thromboprophylaxis, Cell Product Quality and Mode of Delivery for Treatment Safety and Efficacy.
32574262 2020. Interferon-alpha2b Treatment for COVID-19.
32574259 2020. Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19.
32574258 2020. Could BCG Vaccination Induce Protective Trained Immunity for SARS-CoV-2?
32582742 2020. The Use of Microbial Accessible and Fermentable Carbohydrates and/or Butyrate as Supportive Treatment for Patients With Coronavirus SARS-CoV-2 Infection.

32574339 2020. Lung Surfactant for Pulmonary Barrier Restoration in Patients With COVID-19 Pneumonia.
32574332 2020. Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir.
32574331 2020. May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence.
32574327 2020. Therapeutic Algorithm for Use of Melatonin in Patients With COVID-19.
32574320 2020. Doxycycline: From Ocular Rosacea to COVID-19 Anosmia. New Insight Into the Coronavirus Outbreak.

32582138 2020. Intestinal Flora as a Potential Strategy to Fight SARS-CoV-2 Infection.
32582137 2020. Biosurfactants: A Covid-19 Perspective.
32582134 2020. Main Clinical Features of COVID-19 and Potential Prognostic and Therapeutic Value of the Microbiota in SARS-CoV-2 Infections.
32582766 2020. Does Early Childhood Vaccination Protect Against COVID-19?
32581810 2020. Combination of Ruxolitinib and Eculizumab for Treatment of Severe SARS-CoV-2-Related Acute Respiratory Distress Syndrome: A Controlled Study.
32581809 2020. Repositioning Chromones for Early Anti-inflammatory Treatment of COVID-19.
32574238 2020. An Open Question: Is It Rational to Inhibit the mTor-Dependent Pathway as COVID-19 Therapy?

32574290 2020. Using Probiotics to Flatten the Curve of Coronavirus Disease COVID-2019 Pandemic.
32574289 2020. Therapeutic Options for Coronavirus Disease 2019 (COVID-19) - Modulation of Type I Interferon Response as a Promising Strategy?
32547908 2020. Ultraviolet irradiation doses for coronavirus inactivation - review and analysis of coronavirus photoinactivation studies.
32566483 2020. Doxycycline as a potential partner of COVID-19 therapies.

32546458 2020. Covid-19 chemoprophylaxis: Ethics of prevention based on anecdotal evidence.
32540428 2020. Eltrombopag is a potential target for drug intervention in SARS-CoV-2 spike protein.
32537482 2020. Screening and druggability analysis of some plant metabolites against SARS-CoV-2: An integrative computational approach.
32544867 2020. Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trial.
32544570 2020. Five severe COVID-19 pneumonia patients treated with triple combination therapy with lopinavir/ritonavir, hydroxychloroquine, and interferon beta-1b.
32534513 2020. COVID-19 Pandemic Hemoperfusion Therapy Versus Plasma Exchange Therapy in Intensive Care.
32534509 2020. Management of COVID-19 Virus Infection by Convalescent Plasma.
32534505 2020. Sitagliptin Repositioning in SARS-CoV-2: Effects on ACE-2, CD-26, and Inflammatory Cytokine Storms in the Lung.
32558435 2020. Rationale for Evaluating PDE4 Inhibition for Mitigating against Severe Inflammation in COVID-19 Pneumonia and Beyond.
32565398 2020. Effects of Micronutrients or Conditional Amino Acids on COVID-19-Related Outcomes: An Evidence Analysis Center Scoping Review.
32587093 2020. Inhibition of SARS-CoV-2 by type I and type III interferons.
32552595 2020. Natural compounds from Clerodendrum spp. as possible therapeutic candidates against SARS-CoV-2: An in silico investigation.
32552534 2020. Identification of a novel dual-target scaffold for 3CLpro and RdRp proteins of SARS-CoV-2 using 3D-similarity search, molecular docking, molecular dynamics and ADMET evaluation.
32552462 2020. Identification of bioactive compounds from Glycyrrhiza glabra as possible inhibitor of SARS-CoV-2 spike glycoprotein and non-structural protein-15: a pharmacoinformatics study.
32552361 2020. Combined drug repurposing and virtual screening strategies with molecular dynamics simulation identified potent inhibitors for SARS-CoV-2 main protease (3CLpro).
32544024 2020. An in silico approach for identification of novel inhibitors as potential therapeutics targeting COVID-19 main protease.
32543978 2020. Computational investigation on Andrographis paniculata phytochemicals to evaluate their potency against SARS-CoV-2 in comparison to known antiviral compounds in drug trials.
32538276 2020. Repurposing cefuroxime for treatment of COVID-19: a scoping review of in silico studies.
32554907 2020. Current global vaccine and drug efforts against COVID-19: Pros and cons of bypassing animal trials.
32603772 2020. Targeting inflammation and cytokine storm in COVID-19.

32594863 2020. The potential role of nanomedicine on COVID-19 therapeutics.
32593519 2020. Regulatory consideration on preparation and clinical use of COVID-19 convalescent plasma.

32605306 2020. Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2.
32546811 2020. Coronavirus breakthrough: dexamethasone is first drug shown to save lives.
32071447 2020. More than 80 clinical trials launch to test coronavirus treatments.
32214238 2020. How blood from coronavirus survivors might save lives.
32597513 2020. New intrigant possibility for prevention of coronavirus pneumonitis: natural purified polyphenols.
32541085 2020. Citokinellenes terapia az uj tipusu koronavirus okozta megbetegedes (COVID-19) kezeleseben - tocilizumab elsokent valo alkalmazasa egy hazai infektologiai osztalyon.
32564002 2020. Az elso ket sikeres, convalescens friss fagyasztott plazmaval torteno terapia hazai alkalmazasa intenziv osztalyon kezelt, kritikus allapotu, COVID-19-fertozesben szenvedo betegekben: (A COVID-19-pandemia orvosszakmai kerdesei)
32579049 2020. Photobiomodulation: Shining Light on COVID-19.
32579493 2020. Response to: Can Transdermal Photobiomodulation Help Us at the Time of COVID-19?
32579491 2020. Author's Response to Ferreira: Can Transdermal Photobiomodulation Help Us at the Time of COVID-19? An Update.

32584322 2020. INFUSION OF CONVALESCENT PLASMA IS ASSOCIATED WITH CLINICAL IMPROVEMENT IN CRITICALLY ILL PATIENTS WITH COVID-19: A PILOT STUDY.

32604223 2020. Therapeutic Potential of B-1a Cells in COVID-19.
32553502 2020. Ultrafast response of the French Society of Pharmacology and Therapeutics to the COVID-19 pandemic.
32561113 2020. Current treatment approaches for COVID-19 and the clinical value of transfusion-related technologies.
32574447 2020. HBO2 for COVID-19: Clinical trials at clinicaltrials.gov.
32574446 2020. UHMS Position Statement: Hyperbaric Oxygen (HBO2) for COVID-19 Patients.
32574433 2020. Hyperbaric oxygen therapy may be effective to improve hypoxemia in patients with severe COVID-2019 pneumonia: two case reports.
32574432 2020. Hyperbaric oxygen as a treatment for COVID-19 infection?
32567972 2020. Autophagy and SARS-CoV-2 infection: Apossible smart targeting of the autophagy pathway.

32530282 2020. Computational Determination of Potential Inhibitors of SARS-CoV-2 Main Protease.
32539372 2020. Fragment Molecular Orbital Based Interaction Analyses on COVID-19 Main Protease - Inhibitor N3 Complex (PDB ID: 6LU7).
32551639 2020. Discovery of New Hydroxyethylamine Analogs against 3CL(pro) Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure-Activity Relationship Studies.

32560227 2020. Vaccines and Therapies in Development for SARS-CoV-2 Infections.

32524645 2020. Practice considerations on the use of investigational anti-COVID-19 medications: Dosage, administration and monitoring.
32535939 2020. Critical Need for Implementation of Clinical Pharmacology Principles in Developing Drugs for the Treatment or Prevention of COVID-19.
32557271 2020. Possible role of vitamin D in Covid-19 infection in pediatric population.
32551855 2020. Effects of Gene-Eden-VIR and Novirin on SARS-CoV: Implications for COVID-19.
32560382 2020. "Monoclonal-Type" Plastic Antibodies for COVID-19 Treatment: What Is the Idea?
32592703 2020. Retrospective, multicenter study on the impact of baricitinib in COVID-19 moderate pneumonia.
32579985 2020. Etoposide treatment adjunctive to immunosuppressants for critically ill COVID-19 patients: Etoposide for severe COVID-19 patients.

32515499 2020. Higher levels of IL-6 early after tocilizumab distinguish survivors from non-survivors in COVID-19 pneumonia: a possible indication for deeper targeting IL-6.

32530507 2020. Can steroids reverse the severe COVID-19 induced "cytokine storm"?

32519764 2020. Could melatonin be used in COVID-19 patients with laryngopharyngeal reflux disease?

32454982 2020. Amid COVID-19: the importance of developing an positive adverse drug reaction (ADR) and medical device incident (MDI) reporting culture for Global Health and public safety.
32542782 2020. SARS-CoV-2 Viral Inactivation Using Low Dose Povidone-Iodine Oral Rinse-Immediate Application for the Prosthodontic Practice.
32582350 2020. Herbs that might be effective for the management of COVID-19: A bioinformatics analysis on anti-tyrosine kinase property.
32600410 2020. Boning up: amino-bisphophonates as immunostimulants and endosomal disruptors of dendritic cell in SARS-CoV-2 infection.
32579195 2020. Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial.
32579190 2020. Colchicine for the Treatment of Myocardial Injury in Patients With Coronavirus Disease 2019 (COVID-19)-An Old Drug With New Life?

32539990 2020. A minimal common outcome measure set for COVID-19 clinical research.
32402512 2020. A Case of Coronavirus Disease 2019 Treated With Ciclesonide.
32577056 2020. The Nrf2 Activator (DMF) and Covid-19: Is there a Possible Role?
32537610 2020. Inhibition of metalloproteinases in therapy for severe lung injury due to COVID-19.
32563969 2020. Can hyperimmune anti-CMV globulin substitute for convalescent plasma for treatment of COVID-19?

32540604 2020. Iodine, a preventive and curative agent in the COVID-19 pandemic?
32562911 2020. Hypothesis for the management and treatment of the COVID-19-induced acute respiratory distress syndrome and lung injury using mesenchymal stem cell-derived exosomes.
32554324 2020. Noradrenergic and serotonergic drugs may have opposing effects on COVID-19 cytokine storm and associated psychological effects.
32540603 2020. Repositioning of pentoxifylline as an immunomodulator and regulator of the renin-angiotensin system in the treatment of COVID-19.
32563970 2020. Deceiving SARS-CoV-2 molecular-tropism clues - A combinational contemporary strategy.

32554149 2020. Aminoglycosides can be a better choice over macrolides in COVID-19 regimen: Plausible mechanism for repurposing strategy.

32538585 2020. Reply to: What we are talking about when we talk of steroid in COVID-19?
32538591 2020. Convalescent plasma and covid-19 treatment.
32447695 2020. Therapien gegen COVID-19 - ein Update : SARS-CoV-2-Pandemie.
32405836 2020. Wie ernahre ich mich am besten in Zeiten der Corona-Pandemie? : COVID-19 und Ernahrungsmedizin.

32545268 2020. Potential of Flavonoid-Inspired Phytomedicines against COVID-19.
32561155 2020. Inmunoglobulinas por via intravenosa: una alternativa terapeutica a tener en cuenta en el paciente trasplantado renal con COVID-19.

32550240 2020. Azithromycin Should Not Be Used to Treat COVID-19.
32582329 2020. How Nutrition can help to fight against COVID-19 Pandemic.
32582320 2020. Beyond transmission: Dire need for integration of nutrition interventions in COVID-19 pandemic-response strategies in Developing Countries like Pakistan.
32582873 2020. Evaluation of Ultraviolet-C Light for Rapid Decontamination of Airport Security Bins in the Era of SARS-CoV-2.
32566414 2020. Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach.
32578336 2020. Buying time: Drug repurposing to treat the host in COVID-19H.
32380821 2020. Therapeutic plasma exchange as a rescue therapy in patients with coronavirus disease 2019: a case series.
32383835 2020. Acute respiratory distress syndrome and steroids in the shadow of coronavirus disease 2019.
32540682 2020. Psychotropics drugs with cationic amphiphilic properties may afford some protection against SARS-CoV-2: A mechanistic hypothesis.
32590235 2020. TB infection and BCG vaccination: are we protected from COVID-19?

32583654 2020. Baricitinib en el tratamiento de infeccion por SARS-CoV-2.
32595974 2020. The successful use of therapeutic plasma exchange for severe COVID-19 acute respiratory distress syndrome with multiple organ failure.
32548259 2020. Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents.
32601278 2020. Numerical evaluation of spray position for improved nasal drug delivery.
32581288 2020. Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses.
32576928 2020. DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1.
32571838 2020. A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2.
32540904 2020. Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies.
32540903 2020. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.
32540902 2020. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability.
32540901 2020. Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.
32540900 2020. Broad neutralization of SARS-related viruses by human monoclonal antibodies.
32570174 2020. SARS-CoV-2 infection and stem cells: Interaction and intervention.
32592163 2020. 'Primed' Mesenchymal Stem Cells: a Potential Novel Therapeutic for COVID19 Patients.
32564256 2020. Regenerative Medicine in COVID-19 Treatment: Real Opportunities and Range of Promises.
32577236 2020. Preventing SARS-CoV-2 infection by blocking a tissue serine protease.
32539647 2020. Inhaled nitric oxide treatment in spontaneously breathing COVID-19 patients.
32583289 2020. Statistical Evaluation of Clinical Trials Under COVID-19 Pandemic.
32557317 2020. New FDA Guidance on General Clinical Trial Conduct in the Era of COVID-19.

32540345 2020. Anti-SARS-CoV-2 hyperimmune plasma workflow.
32563550 2020. Plasma from donors convalescent from SARS-CoV-2 infection-A matter of priorities.
32359090 2020. Convalescent plasma: possible therapy for novel coronavirus disease 2019.
32563584 2020. Successful Treatment of Severe COVID-19 Pneumonia With Clazakizumab in a Heart Transplant Recipient: A Case Report.

32580895 2020. Targeting JAK-STAT Signaling to Control Cytokine Release Syndrome in COVID-19.

32551456 2020. Use of Spironolactone in SARS-CoV-2 ARDS Patients.
32595362 2020. Mesenchymal stem cell derived extracellular vesicles: promising immunomodulators against autoimmune, autoinflammatory disorders and SARS-CoV-2 infection.
32595360 2020. Interaction of certain monoterpenoid hydrocarbons with the receptor binding domain of 2019 novel coronavirus (2019-nCoV), transmembrane serine protease 2 (TMPRSS2), cathepsin B, and cathepsin L (CatB/L) and their pharmacokinetic properties.
32595359 2020. Potentials of plant-based substance to inhabit and probable cure for the COVID-19.

32595357 2020. SARS-CoV-2 neutralizing antibody development strategies.
32595355 2020. Virtual drug repurposing study against SARS-CoV-2 TMPRSS2 target.
32585913 2020. SARS-CoV-2: An Update on Potential Antivirals in Light of SARS-CoV Antiviral Drug Discoveries.
32575350 2020. Merit of an Ursodeoxycholic Acid Clinical Trial in COVID-19 Patients.

32560646 2020. Non-optimal effectiveness of convalescent plasma transfusion and hydroxychloroquine in treating COVID-19: a case report.
32592817 2020. Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection.
32569708 2020. COVID-19: Review on latest available drugs and therapies against SARS-CoV-2. Coagulation and inflammation cross-talking.
32565126 2020. Targeting the SARS-CoV-2 spike glycoprotein prefusion conformation: virtual screening and molecular dynamics simulations applied to the identification of potential fusion inhibitors.
32545799 2020. Potential Antiviral Options against SARS-CoV-2 Infection.
32573126 2020. Phosphodiesterase Type 5 Inhibitors and COVID-19: Are They Useful In Disease Management?