Disease Models

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32482825 2020. Testing animals for SARS-CoV-2.
32318665 2020. Age-related rhesus macaque models of COVID-19
32259477 ä. Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
32405028 2020. Infection of bat and human intestinal organoids by SARS-CoV-2.
32215622 ä. Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility
32378471 2020. Animal models for emerging coronavirus: progress and new insights
32408338 2020. Pathogenesis and transmission of SARS-CoV-2 in golden hamsters.
32303993 ä. Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids
32303590 2020. Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model
32396922 2020. Respiratory disease in rhesus macaques inoculated with SARS-CoV-2.
32380511 2020. The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice
32369435 2020. Canine Respiratory Coronavirus: A Naturally Occurring Model of COVID-19?
32462701 2020. Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology.
32467379 2020. The search for a COVID-19 animal model.
32299928 2020. From mice to monkeys, animals studied for coronavirus answers.
31583825 2019. Improving immunological insights into the ferret model of human viral infectious disease
15892035 2005. An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus
16501078 2006. Modeling the Early Events of Severe Acute Respiratory Syndrome Coronavirus Infection In Vitro
23029269 2012. Lack of Innate Interferon Responses during SARS Coronavirus Infection in a Vaccination and Reinfection Ferret Model
22936401 2012. Correlation between TGF beta1 expression and proteomic profiling induced by severe acute respiratory syndrome coronavirus papain?like protease
32424314 2020. SARS-CoV-2 causes COVID-19-like disease in cynomolgus macaques.
32426999 2020. Gnotobiotic Rats Reveal That Gut Microbiota Regulates Colonic mRNA of Ace2, the Receptor for SARS-CoV-2 Infectivity.
32478897 2020. Conditional cell reprogramming for modeling host-virus interactions and human viral diseases.
32498696 2020. COVID-19 preclinical models: human angiotensin-converting enzyme 2 transgenic mice.
32532942 2020. MERS-CoV and SARS-CoV infections in animals: a systematic review and meta-analysis of prevalence studies.
32516571 2020. Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2.
32446313 2020. Organoids of human airways to study infectivity and cytopathy of SARS-CoV-2.
32518047 2020. Cadaverless anatomy: Darkness in the times of pandemic Covid-19.
32427981 2020. Organoids demonstrate gut infection by SARS-CoV-2.
32533111 2020. A versatile mouse model of COVID-19.
32485164 2020. A Mouse Model of SARS-CoV-2 Infection and Pathogenesis.
32483314 2020. COVID-19: organoids go viral.
32500482 2020. Induced Pluripotent Stem Cells (iPSCs) Derived 3D Human Lung Organoids from Different Ethnicities to Understand the SARS-CoV2 Severity/Infectivity Percentage.
32434416 2020. Mice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness.

32517266 2020. Propagation, Inactivation, and Safety Testing of SARS-CoV-2.

32591839 2020. Infectability of human BrainSphere neurons suggests neurotropism of SARS-CoV-2.
32579880 2020. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
32565270 2020. Editorial: Why is modeling COVID-19 so difficult?

32568027 2020. SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology.

32562199 2020. Isolation and Growth Characteristics of SARS-CoV-2 in Vero Cell.
32581126 2020. Opinion: What models can and cannot tell us about COVID-19.
32571934 2020. Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development.
32553273 2020. A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.
32558946 2020. Distinct infection process of SARS-CoV-2 in human bronchial epithelial cells line.
32553545 2020. In Vitro and Animal Models for SARS-CoV-2 research.
32607866 2020. A Comprehensive Review of Animal Models for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV.
32582703 2020. Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids.
32602046 2020. Long Term Culture of Human Kidney Proximal Tubule Epithelial Cells Maintains Lineage Functions and Serves as an Ex vivo Model for Coronavirus Associated Kidney Injury.
32559081 2020. Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane.
32541908 2020. Modeling SARS-CoV-2 infection in mice.

32273603 2020. Functionally assessing coronavirus entry.

32606457 2020. Mini organs reveal how the coronavirus ravages the body.
32744989 2020. Small Particle Aerosol Exposure of African Green Monkeys to MERS-CoV as a Model for Highly Pathogenic Coronavirus Infection.
32335973 2020. Of mice and men: COVID-19 challenges translational neuroscience.
32574234 2020. The Zebrafish Disease and Drug Screening Model: A Strong Ally Against Covid-19.

32887790 2020. Cell and animal models of SARS-CoV-2 pathogenesis and immunity.
32811514 2020. Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase.
32814760 2020. Comparison of nonhuman primates identified the suitable model for COVID-19.
32820248 2020. Animal and translational models of SARS-CoV-2 infection and COVID-19.
32733785 2020. Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2.
32337177 2020. Animal models for the risk assessment of viral pandemic potential.
32841215 2020. Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease.
32750141 2020. Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
32867617 2020. Human Induced Pluripotent Stem Cell-Derived Lung Epithelial System for SARS-CoV-2 Infection Modeling and Its Potential in Drug Repurposing.
32876341 2020. SARS-CoV-2 targets neurons of 3D human brain organoids.
32662981 2020. Can the Environmental Phagocyte Acanthamoeba Be a Useful Model to Study SARS-CoV-2 Pathogenicity, Infectivity, and Evasion of Cellular Immune Defenses?
32725927 ?. The ACE2?deficient mouse: A model for a cytokine storm?driven inflammation.
32611917 2020. Evaluation of the susceptibility of mice & hamsters to SARS-CoV-2 infection.
32837985 2020. Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2.
32773420 2020. Transcriptome & viral growth analysis of SARS-CoV-2-infected Vero CCL-81 cells.
32854108 2020. A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
32880236 2020. 2020 ACVP, ASVCP, and ISACP Concurrent Annual Meeting: From Novel Insights Into COVID-19 to Unconventional Animal Models.
32733785 2020. Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2.
32750141 2020. Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
32744989 2020. Small Particle Aerosol Exposure of African Green Monkeys to MERS-CoV as a Model for Highly Pathogenic Coronavirus Infection.
32730733 2020. Differential Tropism of SARS-CoV and SARS-CoV-2 in Bat Cells.
32749592 2020. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice.
32640120 2020. Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation.
32260595 2020. Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes.
31694296 2019. The Porcine Deltacoronavirus Replication Organelle Comprises Double-Membrane Vesicles and Zippered Endoplasmic Reticulum with Double-Membrane Spherules.
31905881 2019. Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites.
32806708 2020. Of Mice and Men: The Coronavirus MHV and Mouse Models as a Translational Approach to Understand SARS-CoV-2.
32749592 2020. Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice.
32772513 2020. Delayed severe cytokine storm and immune cell infiltration in SARS-CoV-2-infected aged Chinese rhesus macaques.
32723427 2020. Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection.
32701249 2020. COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2.
C7340389 ?. SARS-CoV-2 in fruit bats ferrets pigs and chickens: an experimental transmission study.
C7302768 ?. Host range of SARS-CoV-2 and implications for public health.
32613170 2020. Commentary on two reports on animal models of COVID-19.
32725927 ?. The ACE2?deficient mouse: A model for a cytokine storm?driven inflammation.
C7323681 2020. Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection.
C7332447 ?. A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition.
28865134 2018. Human Pulmonary 3D Models For Translational Research.

C7340063 2020. Susceptibility of selected domestic animals to COVID-19.

32732280 2020. Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.
32690933 2020. Syrian hamsters as a small animal model for COVID-19 research.
C7298460 ?. Giovanni Di Guardo: Animal models and pathogenetic insights to CoViD-19.
32611917 2020. Evaluation of the susceptibility of mice & hamsters to SARS-CoV-2 infection.
32773086 2020. Giovanni Di Guardo: Animal Models and Pathogenetic Insights to Covid-19.
32613937 2020. SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines.
32698441 2020. Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters.

32063900 2019. Isolation and Selection of Duck Primary Cells as Pathogenic and Innate Immunologic Cell Models for Duck Plague Virus.

21538303 2011. Coronaviruses: propagation, quantification, storage, and construction of recombinant mouse hepatitis virus.

32745172 2020. Transient lymphopenia and interstitial pneumonia with endotheliitis in SARS-CoV-2-infected macaques.