Candidate Compounds Covid19
coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.
current items will be put into the subsections. subsections with contents are marked with content. the others are pending data.
- reviews on covid drug development with content
- Patients on biologicals
- HMGB1, RAGE
- pre-Interleukin 6 with content
- post-Interleukin 6
- pre-TNFalpha
- post-TNFalpha
- pre-Interleukin 17
- post-Interleukin 17
- pre-Interleukin 1
- post-Interleukin 1
- Inflammasome
- NK-kappaB
- STAT 3
- JAK Janus Kinase
- Corticosteroids
- Cytokine absorbers
- Target Complement system
- Target Extracellular traps
- Anticoagulant in covid19
- Antioxidants
- Stem cells
- MDSC cells
- Immunodeviation e.g. by adjuvants or other vaccinations
- Active vaccine with cotent
32162456 2020. Rapid Identification of Potential Inhibitors of SARS-CoV-2 Main Protease by Deep Docking of 1 3 Billion Compounds
Microbiome as target
32356654 ä. Considering the Effects of Microbiome and Diet on SARS-CoV-2 Infection: Nanotechnology Roles
stem cells
32257554 2020. Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia
32257537 2020. Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia
32283815 2020. Mesenchymal Stromal Cell Secretome for Severe COVID-19 Infections: Premises for the Therapeutic Use
32241793 2020. Clinical course of COVID-19 in a series of patients with chronic arthritis treated with immunosuppressive targeted therapies
CRISPR genome editing technology
32353252 ä. Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza
Virus interference
32071427 2020. Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses
resilience enhancement
32229705 2020. Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections
32311498 ä. The impact of nutrition on COVID-19 susceptibility and long-term consequences
32276453 2020. Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats
psychoneuroimmunology
32234338 ä. Using psychoneuroimmunity against COVID-19
Exercise
32311497 ä. The immunological case for staying active during the COVID-19 pandemic
Topical agents opening up the world of nano...
32247038 2020. Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19
32222466 2020. The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China
32266375 ä. Inquiring into Benefits of Independent Activation of Non-Classical Renin-Angiotensin System in the Clinical Prognosis and Reduction of COVID-19 mortality
32305181 ä. ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection
32360083 ä. Modulation of Hb-O2 affinity to improve hypoxemia in COVID-19 patients
32277367 ä. Rheumatologists? perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets
32373721 2020. Low dose lung radiotherapy for COVID-19 pneumonia The rationale for a cost-effective anti-inflammatory treatment
32241301 2020. A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19
32318324 ä. Depriving Iron Supply to the Virus Represents a Promising Adjuvant Therapeutic Against Viral Survival
32360420 ä. Cytokine storm intervention in the early stages of COVID-19 pneumonia
32335366 2020. Can dapagliflozin have a protective effect against COVID-19 infection? A hypothesis
32333972 ä. Letter to the Editor in response to the article ?COVID-19 and diabetes: Can DPP4 inhibition play a role??
32333966 2020. COVID-19 and diabetes: Is this association driven by the DPP4 receptor? Potential clinical and therapeutic implications
32333969 ä. Response to COVID -19 and Diabetes: Can DPP4 Inhibition Play a Role? ? GLP-1 Might Play One Too
32283128 ä. Should anti-diabetic medications be reconsidered amid COVID-19 pandemic? on ace2 via adam17, nfkb via dpp4
32325124 ä. Vaporization, bioactive formulations and a marine natural product: different perspectives on antivirals
32249203 ä. Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
32333818 2020. COVID-19: lambda interferon against viral load and hyperinflammation
32228222 2020. Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension
C7118608 ä. A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification System
32065055 2020. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
32292627 ä. Clinical study of mesenchymal stem cell treating acute respiratory distress syndrome induced by epidemic Influenza A (H7N9) infection, a hint for COVID-19 treatment
32347925 ä. Statin therapy in COVID-19 infection
32337546 ä. Colchicine as a potent anti-inflammatory treatment in COVID-19: can we teach an old dog new tricks?
32282032 ä. Neprilysin inhibitor?angiotensin II receptor blocker combination (sacubitril/valsartan): rationale for adoption in SARS-CoV-2 patients
32285293 ä. Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV
32265310 ä. Current Status of Cell-Based Therapies for Respiratory Virus Infections: Applicability to COVID-19
32271462 2020. Inositol and pulmonary function Could myo-inositol treatment downregulate inflammation and cytokine release syndrome in SARS-CoV-2?
32329380 2020. Adipose-derived stromal stem cells (ASCs) as a new regenerative immediate therapy combating coronavirus (COVID-19)-induced pneumonia
32312129 2020. The role of additive manufacturing and antimicrobial polymers in the COVID-19 pandemic
32117569 2020. Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China
32251729 ä. The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design
32247692 ä. Faecal-oral transmission of SARS-COV-2: practical implications
32367287 ä. New evidence of SARS-CoV-2 transmission through the ocular surface
32251365 ä. Considering mutational meltdown as a potential SARS-CoV-2 treatment strategy
32186952 2020. COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics
32366728 2020. Medical Education During the COVID-19 Pandemic: A Single Institution Experience
32366726 2020. Management of Asthma in Children during COVID-19 Pandemic
32366725 2020. COVID -19 Pandemic: The Challenges for Pediatric Oncology
32341599 2020. Is Immuno-modulation the Key to COVID-19 Pandemic?
32328406 ä. Vaccines for SARS-CoV-2: Lessons from Other Coronavirus Strains
32272396 ä. The Possible of Immunotherapy for COVID-19: a Systematic Review
32234466 ä. Coronavirus disease 2019 (COVID-19): current status and future perspectives
32283177 ä. Coronavirus (COVID-19), First Indication of Efficacy of Gene-Eden-VIR/Novirin in SARS-CoV-2 Infections
32226290 2020. Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19
32305009 ä. Investigating hypothiocyanite against SARS-CoV-2
32354030 2020. Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work
32368489 2020. The pathogenesis and alternative treatment of SARS-CoV2
32336674 ä. COVID-19 Emergency Responders in FDA?s Center for Drug Evaluation and Research
32317220 ä. The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19
32326602 2020. Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19
32326426 2020. COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression
32359878 2020. Application of plasma exchange in association with higher dose CVVH in Cytokine Storm Complicating COVID-19
32171450 2020. Identification of potential cross-protective epitope between a new type of coronavirus (2019-nCoV) and severe acute respiratory syndrome virus
32373322 ä. Fighting COVID-19 with water dehydration of mucous glycans
32293807 2020. Systematic review of the efficacy and safety of antiretroviral drugs against SARS, MERS or COVID?19: initial assessment
32356252 ä. COVID-19: Therapeutics and Their Toxicities
32356251 ä. Medical Toxicology and COVID-19: Our Role in a Pandemic
32052466 2020. Potential interventions for novel coronavirus in China: A systematic review
32346490 ä. Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase
32324533 2020. Prevention and therapy of COVID-19 via exogenous estrogen treatment for both male and female patients
32291198 2020. Impact of Nutrition and Diet on COVID-19 Infection and Implications for Kidney Health and Kidney Disease Management
32321635 2020. Old and new antirheumatic drugs for the treatment of COVID-19
32317113 2020. COVID-19 therapeutic options for patients with kidney disease
32035018 2020. Reducing mortality from 2019-nCoV: host-directed therapies should be an option
32220278 2020. Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?
32353328 2020. What policy makers need to know about COVID-19 protective immunity
32305088 2020. Flooded by the torrent: the COVID-19 drug pipeline
32339473 ä. Probiotics and COVID-19: one size does not fit all
32199468 ä. Use of antiviral drugs to reduce COVID-19 transmission
32278361 ä. Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19
32325035 ä. Plea for multitargeted interventions for severe COVID-19
32113510 2020. Convalescent plasma as a potential therapy for COVID-19
32113509 2020. COVID-19: combining antiviral and anti-inflammatory treatments
32368737 2020. Preventing COVID-19-induced pneumonia with anticytokine therapy
32278693 2020. In silico studies on therapeutic agents for COVID-19: Drug repurposing approach
32198163 2020. Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection
32265331 2020. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection
32296777 2020. Mesenchymal stem cells and management of COVID-19 pneumonia
32289117 2020. Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus
32292909 2020. Target Virus or Target Ourselves for COVID-19 Drugs Discovery?-Lessons learned from anti-influenzas virus therapies
32220710 2020. Renin-angiotensin system: The unexpected flaw inside the human immune system revealed by SARS-CoV-2
- riociguat?
32353740 2020. Serum albumin-mediated strategy for the effective targeting of SARS-CoV-2
32344313 ä. Can pioglitazone be potentially useful therapeutically in treating patients with covid-19?
32344312 2020. Potential effect of natural and anabolizan steroids in elderly patient with COVID-19
32344310 2020. Respiratory conditions in coronavirus disease 2019 (COVID-19): Important considerations regarding novel treatment strategies to reduce mortality
32339777 2020. May IL-17 have a role in COVID-19 infection?
32335456 2020. The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases?
C7158785 ä. Convalescent plasma: A possible treatment of COVID-19 in India
32353355 ä. Testosterone, a key hormone in the context of COVID-19 pandemic
32370766 2020. Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines
32307014 2020. Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19
32255312 2020. A possible probiotic (S salivarius K12) approach to improve oral and lung microbiotas and raise defenses against SARS-CoV-2
32365556 2020. Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-gamma as Candidates for Cytokine Storm Modulation in COVID-19 Disease
32231348 2020. Emerging prophylaxis strategies against COVID-19
32187463 ä. Covid-19 ? The Search for Effective Therapy
32354113 2020. On Facing the SARS-CoV-2 (COVID-19) with Combination of Nanomaterials and Medicine: Possible Strategies and First Challenges
32326343 2020. Can Nanotechnology and Materials Science Help the Fight against SARS-CoV-2?
32203437 ä. Insights from nanomedicine into chloroquine efficacy against COVID-19
32296135 ä. COVID-19: risk for cytokine targeting in chronic inflammatory diseases?
32355330 ä. Inactivated vaccine for SARS-CoV-2
32346092 ä. Cancer therapy tool informs COVID-19 vaccines
32346094 ä. COVID-19 vaccine design: the Janus face of immune enhancement
32317716 ä. The potential danger of suboptimal antibody responses in COVID-19
32313660 2020. A short review on antibody therapy for COVID-19
32287799 2020. Drug trials under way
32194995 2020. The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines
32340216 2020. Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections
32342019 ä. Exercise against SARS-CoV-2 (COVID-19): Does workout intensity matter? (A mini review of some indirect evidence related to obesity)
32258207 2020. High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019
32284951 2020. Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options
32214286 2020. Expanded Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) as a Therapeutic Strategy in Managing Critically Ill COVID-19 Patients: The Case for Compassionate Use
32098302 2020. Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development
32333199 ä. Coronavirus in Hematologic Malignancies: Targeting Molecules Beyond the Angiotensin-Converting Enzyme 2 (ACE2) Wall in COVID-19
32307559 ä. Management for patients with pediatric surgical disease during the COVID-19 epidemic
32290348 2020. COVID-19: A Brief Overview of the Discovery Clinical Trial
32360585 ä. Current targeted therapeutics against COVID-19: based on first-line experience in china
32360583 ä. Efficacy and safety of current therapeutic options for COVID-19 - lessons to be learnt from SARS and MERS epidemic: A systematic review and meta-analysis
32360480 ä. Candidate drugs against SARS-CoV-2 and COVID-19
32369479 2020. Antibody-based therapies for COVID-19: Can Europe move faster?
32343686 2020. Pandemic responses: Planning to neutralize SARS-CoV-2 and prepare for future outbreaks
32253318 2020. Effectiveness of convalescent plasma therapy in severe COVID-19 patients
32229574 2020. News Feature: Avoiding pitfalls in the pursuit of a COVID-19 vaccine
32342871 ä. Is low dose radiation therapy a potential treatment for COVID-19 pneumonia?
32342874 ä. Low dose radiation therapy for COVID-19 pneumonia: a double-edged sword
32256547 2020. Clinical trials on drug repositioning for COVID-19 treatment
32232552 ä. Coronavirus disease 2019 (COVID-19) and anti-rheumatic drugs
32124179 ä. Clinical trials for the treatment of Coronavirus disease 2019 (COVID-19): A rapid response to urgent need
32278175 ä. COVID-19: A promising cure for the global panic
32347054 2020. Strategies for vaccine development of COVID-19
32133159 2020. Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia
32366290 2020. Mesenchymal stem cells as a potential therapy for COVID-19
C7110269 ä. COVID-19 Outbreak: an Update on Therapeutic Options
32307653 ä. CD147 as a Target for COVID-19 Treatment: Suggested Effects of Azithromycin and Stem Cell Engagement
32281052 ä. Mesenchymal Stem Cell Therapy for COVID-19: Present or Future
32320535 2020. Mesenchymal stem cells as a potential treatment for critically ill patients with coronavirus disease 2019
32362735 ä. Insights into the inhibitory potential of selective phytochemicals against Mpro of 2019-nCoV: a computer-aided study
32347963 2020. An independent appraisal and re-analysis of hydroxychloroquine treatment trial for COVID-19
32343358 2020. Immunoglobulins or convalescent plasma to tackle COVID-19: buying time to save lives - current situation and perspectives
32328234 2020. Does the direct renin inhibitor have a role to play in attenuating severity of the outbreak coronavirus disease 2019 (COVID-19)?
32360140 ä. Bee venom and SARS-CoV-2
32345485 ä. Treatment for emerging viruses: Convalescent plasma and COVID-19
32359789 ä. COVID-19 Convalescent Plasma: Now Is the Time for Better Science
32359788 ä. Convalescent Plasma: Therapeutic Hope or Hopeless Strategy in the SARS-CoV-2 Pandemic
32289548 2020. Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
32247925 ä. Repurposing antimalarials and other drugs for COVID-19
32145386 ä. Remdesivir as a possible therapeutic option for the COVID-19
32334088 ä. SARS-CoV-2 and COVID-19: What are our options? Where should we focus our attention on to find new drugs and strategies?
32325121 ä. Tocilizumab: A new opportunity in the possible therapeutic arsenal against COVID-19
32247927 ä. Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: An evaluation of the evidence
32249063 ä. Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses
32362491 ä. Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses: (Trends in Immunology 41, 355?359; 2020)
32294562 ä. A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease
32371057 ä. Potential applications of plant biotechnology against SARS-CoV-2
32291112 ä. Ongoing Clinical Trials for the Management of the COVID-19 Pandemic
32299202 2020. COVID-19, immune system response, hyperinflammation and repurposing antirheumatic drugs
32293834 2020. Antiviral treatment of COVID-19
32295153 2020. What Does Plant-Based Vaccine Technology Offer to the Fight against COVID-19?
32235387 2020. Progress and Prospects on Vaccine Development against SARS-CoV-2
32034638 ä. Compensation of ACE2 Function for Possible Clinical Management of 2019-nCoV-Induced Acute Lung Injury
32297156 ä. Computational Identification of Small Interfering RNA Targets in SARS-CoV-2
32360300 ä. Natural product-derived phytochemicals as potential agents against coronaviruses: a review
32363219 ä. Binding site analysis of potential protease inhibitors of COVID-19 using AutoDock
32106567 2020. Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies
32098094 2020. Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376
32272550 2020. Antiviral Agents: Discovery to Resistance
32268515 2020. In Silico Discovery of Candidate Drugs against Covid-19
32357553 2020. Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19
32340120 2020. Shedding Light on the Effect of Natural Anti-Herpesvirus Alkaloids on SARS-CoV-2: A Treatment Option for COVID-19
32295237 2020. Molecular Investigation of SARS-CoV-2 Proteins and Their Interactions with Antiviral Drugs
32313883 2020. Inhaled biguanides and mTOR inhibition for influenza and coronavirus (Review)
C7118592 ä. Understanding of guidance for acupuncture and moxibustion interventions on COVID-19 (Second edition) issued by CAAM
| 32312290 2020. Salvage use of tissue plasminogen activator (tPA) in the setting of acute respiratory distress syndrome (ARDS) due to COVID-19 in the USA: a Markov decision analysis |
32377965 ä. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality
32297520 2020. Can spironolactone be used to prevent COVID-19-induced acute respiratory distress syndrome in patients with hypertension?
32297519 2020. COVID-19 and vitamin D?Is there a link and an opportunity for intervention?
32191676 2020. Natural small molecules as inhibitors of coronavirus lipid-dependent attachment to host cells: a possible strategy for reducing SARS-COV-2 infectivity?
32286694 2020. Letter: Covid-19, and vitamin D Authors reply
32281109 2020. Letter: Covid-19, and vitamin D
32339299 2020. Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic?
32330314 2020. Is BCG vaccination affecting the spread and severity of COVID-19?
32349517 2020. Becoming a Faithful Defender: Traditional Chinese Medicine against Coronavirus Disease 2019 (COVID-19)
32164424 2020. COVID-19: An Update on the Epidemiological, Clinical, Preventive and Therapeutic Evidence and Guidelines of Integrative Chinese-Western Medicine for the Management of 2019 Novel Coronavirus Disease
32358817 2020. Dramatic improvement after tocilizumab of severe COVID-19 in a child with sickle cell disease and acute chest syndrome
32282956 2020. Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab
32247518 2020. COVID-19 and Chloroquine/Hydroxychloroquine: is there Ophthalmological Concern?
32207983 2020. Covid-19 infection and mortality: a physiologist?s perspective enlightening clinical features and plausible interventional strategies
32314704 2020. Ivermectin and Novel Coronavirus Disease (COVID-19): Keeping Rigor in Times of Urgency
32359210 2020. Clinical Course of COVID-19 in a Liver Transplant Recipient on Hemodialysis and Response to Tocilizumab Therapy: A Case Report
32324331 2020. COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine
32274985 2020. Novel Coronavirus Disease (COVID-19): The Need for Immunoprevention at Industrial Scale
32352178 2020. Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North-supports vitamin D as a factor determining severity Authors reply
32311755 2020. Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity
32329159 2020. Thoughts on What Chemists Can Contribute to Fighting SARS-CoV-2 - A Short Note on Hand Sanitizers, Drug Candidates and Outreach
32376597 2020. Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series
32345616 2020. Anti-inflammatory therapy may ameliorate the clinical picture of COVID-19
32304395 2020. COVID-19 Respiratory Failure: Targeting Inflammation on VV-ECMO Support
| 32349115 ä. Chloroquine and Hydroxychloroquine Retinal Toxicity Consideration in the Treatment of COVID-19 |
32380318 ä. Why judiciously timed anti-IL 6 therapy may be of benefit in severe COVID-19 infection
32380316 ä. Convalescent plasma in Covid-19: Possible mechanisms of action
32380315 ä. Continuous hydroxychloroquine or colchicine therapy does not prevent infection with SARS-CoV-2: Insights from a large healthcare database analysis
32376396 ä. Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia?
32376395 ä. SARS-CoV-2 infection among patients with systemic autoimmune diseases
| 32376392 ä. Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions |
32376403 ä. Imatinib might constitute a treatment option for lung involvement in COVID-19
| 32376394 ä. Immunomodulatory therapy for the management of severe COVID-19 Beyond the anti-viral therapy: A comprehensive review |
| 32376397 ä. Seven recommendations to rescue the patients and reduce the mortality from COVID-19 infection: An immunological point of view |
32376398 ä. Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Brescia, Italy
32361195 ä. SARS-CoV-2 infection complicated by inflammatory syndrome Could high-dose human immunoglobulin for intravenous use (IVIG) be beneficial?
32304139 ä. Progress and Concept for COVID?19 Vaccine Development
32213152 2020. Are there any Therapeutic Options Currently Available for Wuhan Coronavirus?
32299796 2020. Antirheumatic agents in covid-19: is IL-6 the right target?
| 32376613 2020. Inhibition of SARS-CoV-2 infection by the cyclophilin inhibitor Alisporivir (Debio 025) |
32366720 2020. Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
32312781 2020. Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19
32205349 2020. Updated Approaches against SARS-CoV-2
32229155 2020. Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?
32339387 2020. COVID-19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin
32282033 2020. Initiating adjunct low-dose hydroxyurea therapy for stroke prevention in children with SCA during the COVID-19 pandemic
32362106 2020. Management of conjunctivitis during the COVID-19 pandemic 2020
32302379 2020. The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19-infected patients
32366511 2020. Developing a vaccine for covid-19
32357949 2020. Covid-19: Remdesivir is helpful but not a wonder drug, say researchers
32217607 2020. Covid-19: what treatments are being investigated?
32217555 2020. Covid-19: FDA approves use of convalescent plasma to treat critically ill patients
32209549 2020. Covid-19: trials of four potential treatments to generate "robust data" of what works
32340998 2020. Covid-19: What do we know so far about a vaccine?
32321732 2020. Remdesivir in covid-19
32359080 2020. Off-target ACE2 ligands: Possible therapeutic option for CoVid-19?
32304110 2020. Dosing will be a key success factor in repurposing antivirals for COVID-19
| 32369628 2020. Convalescent donor SARS-COV-2-specific cytotoxic T lymphocyte infusion as a possible treatment option for COVID-19 patients with severe disease has not received enough attention till date |
32369612 2020. Interleukin 6-blockade treatment for severe COVID-19 in two patients with multiple myeloma
32368792 2020. Potential Therapeutic Targets and Promising Drugs for Combating SARS-CoV-2
| 32358833 2020. A rational roadmap for SARS-CoV-2/COVID-19 pharmacotherapeutic research and development IUPHAR Review 29 |
32329520 2020. Current pharmacological treatments for COVID-19: What s next?
32371479 2020. Cytokine Storm Drugs Move from CAR T to COVID-19
32303509 2020. Harnessing CAR T-cell Insights to Develop Treatments for Hyperinflammatory Responses in Patients with COVID-19
32276929 2020. TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?
| 32324951 2020. Drug Development and Medicinal Chemistry Efforts toward SARS-Coronavirus and Covid-19 Therapeutics |
32245590 2020. Traditional Chinese Medicine: an effective treatment for 2019 novel coronavirus pneumonia (NCP)
32379692 ä. Traditional Chinese Medicine treatment of COVID-19
32379639 2020. Herbal medicine for treatment of children diagnosed with COVID-19: A review of guidelines
| 32271624 2020. Will Complement Inhibition be the New Target in Treating COVID-19 Related Systemic Thrombosis? |
32333649 2020. The friendly use of chloroquine in the COVID-19 disease: a warning for the G6PD-deficient males and for the unaware carriers of pathogenic alterations of the G6PD gene
32378737 2020. The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID-19
32356569 2020. Challenges in Drug Development Posed by the COVID-19 Pandemic: An Opportunity for Clinical Pharmacology
32246834 2020. Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019-nCoV Infection
32350860 2020. Dose Rationale for Favipiravir Use in Patients Infected With SARS-CoV-2
32348551 2020. Response to: Optimizing Hydroxychloroquine Dosing for Patients With COVID-19: An Integrative Modeling Approach for Effective Drug Repurposing: Quantitative Clinical Pharmacology Input to SARS-CoV-2 Therapeutics Should Be Based on Robust Data
32302411 2020. Clinical Pharmacology Perspectives on the Antiviral Activity of Azithromycin and Use in COVID-19
32167153 2020. Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
32345063 2020. Truncated IV acetylcysteine treatment duration has potential to safely preserve resources during the COVID-19 pandemic
32315229 2020. COVID-19 and the CRISPR Community Response
32321407 2020. Hispidin and Lepidine E: two Natural Compounds and Folic acid as Potential Inhibitors of 2019-novel coronavirus Main Protease (2019-nCoVMpro), molecular docking and SAR study
| 32297571 2020. SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and Other Drugs for the Treatment of the New Coronavirus |
32334502 2020. The Mechanistic Target of Rapamycin (mTOR): Novel Considerations as an Antiviral Treatment
32133962 2020. Effective Chemicals against Novel Coronavirus (COVID-19) in China
32314492 ä. Doxycycline, a widely used antibiotic in dermatology with a possible anti?inflammatory action against IL?6 in COVID?19 outbreak
32237190 ä. What does androgenetic alopecia have to do with COVID?19? An insight into a potential new therapy
32227357 ä. COVID?19 treatment by repurposing drugs until the vaccine is in sight
32377559 ä. COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus
32374010 2020. Are probiotics effective adjuvant therapeutic choice in patients with COVID-19?
32374009 2020. Potential mechanisms by which the oxygen-ozone (O2-O3) therapy could contribute to the treatment against the coronavirus COVID-19
32369103 ä. Sacubitril/valsartan in COVID-19 patients: the need for trials
32373994 2020. Could host cell receptor alteration prevent SARS-CoV-2 viral entry? - Hype or hope
32373992 2020. MSCs transplantation may be a potential therapeutic strategy for COVID-19 treatment
32373991 2020. In silico screening of natural compounds against COVID-19 by targeting Mpro and ACE2 using molecular docking
32362193 2020. Quadruple therapy for asymptomatic COVID-19 infection patients
32366131 2020. Harnessing the potential of CRISPR-based platforms to advance the field of hospital medicine
32336007 2020. DPP4 inhibition: preventing SARS-CoV-2 infection and/or progression of COVID-19?
32224164 2020. COVID-19 and diabetes: Can DPP4 inhibition play a role?
32278585 2020. Favorable changes of CT findings in a patient with COVID-19 pneumonia after treatment with tocilizumab
| 32337769 2020. (tt bradykinin) Noscapine, a possible drug candidate for attenuation of cytokine release associated with SARS-CoV-2 |
32352361 2020. Facing the SARS-CoV-2 (COVID-19) outbreak with IL-6R antagonists
32359101 2020. A hypothesized role for dysregulated bradykinin signaling in COVID-19 respiratory complications
32281695 2020. Existing bitter medicines for fighting 2019-nCoV-associated infectious diseases
32379896 2020. Knowledge-based structural models of SARS-CoV-2 proteins and their complexes with potential drugs
31690127 2019. Identification of novel proteolytically inactive mutations in coronavirus 3C-like protease using a combined approach
32157732 ä. Harnessing the immune system via Fc?R function in immune therapy: a pathway to next?gen mAbs
32298218 2020. Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19
32317431 2020. Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future
32370727 2020. SARS-CoV-2 & Covid-19: Key-Roles of the Renin-Angiotensin System / Vitamin D Impacting Drug and Vaccine Developments
| 32377694 2020. Towards effective COVID19 vaccines: Updates, perspectives and challenges (Review) |
32338559 2020. Low dose radiation therapy for COVID-19 pneumonia: is there any supportive evidence?
32319538 2020. Zinc and respiratory tract infections: Perspectives for COVID19 (Review)
32310190 2020. Coronavirus drugs: Using plasma from recovered patients as a treatment for COVID-19
32347747 2020. Can melatonin reduce the severity of COVID-19 pandemic?
32268052 2020. Vitamin D, Covid-19 and Children
32268051 2020. Optimisation of Vitamin D Status for Enhanced Immuno-protection Against Covid-19
32338164 2020. SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective
32306860 2020. Moroccan Medicinal plants as inhibitors against SARS-CoV-2 main protease: Computational investigations
32306822 2020. Peptide-like and small-molecule inhibitors against Covid-19
32340551 2020. Natural products may interfere with SARS-CoV-2 attachment to the host cell
32329419 2020. Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach
32329408 2020. Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease
32362235 2020. Understanding the binding affinity of noscapines with protease of SARS-CoV-2 for COVID-19 using MD simulations at different temperatures
32362243 2020. Identification of new anti-nCoV drug chemical compounds from Indian spices exploiting SARS-CoV-2 main protease as target
32364041 2020. Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2
32364011 2020. FDA-approved thiol-reacting drugs that potentially bind into the SARS-CoV-2 main protease, essential for viral replication
32362217 2020. In silico study the inhibition of angiotensin converting enzyme 2 receptor of COVID-19 by Ammoides verticillata components harvested from Western Algeria
32362245 2020. An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study
32345124 2020. An in-silico evaluation of different Saikosaponins for their potency against SARS-CoV-2 using NSP15 and fusion spike glycoprotein as targets
32340562 2020. A molecular modeling approach to identify effective antiviral phytochemicals against the main protease of SARS-CoV-2
32376368 ä. Identifying potential treatments of COVID-19 from Traditional Chinese Medicine (TCM) by using a data-driven approach
32228825 2020. How to reduce the likelihood of coronavirus-19 (CoV-19 or SARS-CoV-2) infection and lung inflammation mediated by IL-1
32171193 2020. Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies
32367767 2020. Potential inhibitors of coronavirus 3-chymotrypsin-like protease (3CL(pro)): an in silico screening of alkaloids and terpenoids from African medicinal plants
32238094 2020. Identification of chymotrypsin-like protease inhibitors of SARS-CoV-2 via integrated computational approach
32345140 2020. Stilbene-based natural compounds as promising drug candidates against COVID-19
32266867 2020. In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)
32248766 2020. Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19
32349031 2020. Role of Dipeptidyl Peptidase 4 Inhibitors in Diabetic Patients with Coronavirus-19 Infection
32173110 2020. A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19
32379348 2020. 3CL hydrolase-based multiepitope peptide vaccine against SARS-CoV-2 using immunoinformatics
32227493 ä. Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID?19
32219882 ä. Controversial treatments: An updated understanding of the coronavirus disease 2019
32104907 ä. A systematic review of lopinavir therapy for SARS coronavirus and MERS coronavirus?A possible reference for coronavirus disease?19 treatment option
32108352 ä. Clinical trial analysis of 2019?nCoV therapy registered in China
32379346 2020. ACE2 Activators for the Treatment of Covid 19 Patients
32374457 2020. The anti-HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV-2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID-19 infections
32369191 2020. Tocilizumab for the treatment of severe coronavirus disease 2019
32356910 2020. Convalescent plasma transfusion for the treatment of COVID-19: Systematic review
32232976 2020. CD-sACE2 inclusion compounds: An effective treatment for coronavirus disease 2019 (COVID-19)
32176361 2020. Potentially repurposing adamantanes for COVID-19
32270515 2020. Does recombinant human Erythropoietin administration in critically ill COVID-19 patients have miraculous therapeutic effects?
32253759 2020. Tocilizumab treatment in COVID-19: A single center experience
32347974 2020. Metformin and COVID-19: A novel deal of an Old Drug
32239514 ä. Comments on Zhang et al: Clinical trial analysis of 2019?nCoV therapy registered in China
32236562 2020. Treating COVID-19 with Chloroquine
| 32378064 ä. Feasibility of Therapeutic Effects of the Cholinergic Anti-Inflammatory Pathway on COVID-19 Symptoms |
32320059 2020. Potential of live pathogen vaccines for defeating the COVID-19 pandemic: history and mechanism
32297988 2020. Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: A systematic review and meta-analysis
32297985 2020. Evaluation of Antiviral Therapies for Coronavirus Disease 2019 (COVID-19) Pneumonia in Shanghai, China
32297987 2020. Off-label Use of Tocilizumab in Patients with SARS-CoV-2 Infection
32293713 2020. Treatment with convalescent plasma for COVID-19 patients in Wuhan, China
32285942 2020. Defining Protective Epitopes for COVID-19 Vaccination Models
32281679 2020. COVID-19: Herd Immunity and Convalescent Plasma Transfer Therapy
32302456 2020. Potential of heparin and nafamostat combination therapy for COVID-19
32376627 2020. Design of potent membrane fusion inhibitors against SARS-CoV-2, an emerging coronavirus with high fusogenic activity
32359402 2020. Considering BCG vaccination to reduce the impact of COVID-19
32380023 ä. Immunomodulation in COVID-19
32367857 2020. Safety of an immunomodulator Mycobacterium w in COVID-19
32367847 2020. Nasopharyngeal wash in preventing and treating upper respiratory tract infections: Could it prevent COVID-19?
32371362 2020. Mesenchymal stem cell (MSc) secretome: A possible therapeutic strategy for intensive-care COVID-19 patients
32366816 2020. An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development
32376359 ä. Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2
32219429 2020. Convalescent Plasma to Treat COVID-19: Possibilities and Challenges
32352484 2020. Testing an Old Therapy Against a New Disease: Convalescent Plasma for COVID-19
32208486 2020. Treating COVID-19-Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics
32297900 2020. Finding Effective Treatments for COVID-19: Scientific Integrity and Public Confidence in a Time of Crisis
32282022 2020. Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review
32347894 2020. The Risks of Prescribing Hydroxychloroquine for Treatment of COVID-19-First, Do No Harm
32243778 2020. Ensuring global access to COVID-19 vaccines
32247324 2020. Global coalition to accelerate COVID-19 clinical research in resource-limited settings
32251638 2020. Baricitinib for COVID-19: a suitable treatment?
32251639 2020. Baricitinib for COVID-19: a suitable treatment? - Authors reply
| 32240961 2020. Routine childhood immunization may protect against COVID-19 |
32372435 2020. Drug repurposing in the era of COVID-19: a call for leadership and government investment
32266987 2020. Corticosteroid treatment of patients with coronavirus disease 2019 (COVID-19)
32324177 2020. Some drugs for COVID-19
32162456 ä. Rapid Identification of Potential Inhibitors of SARS?CoV?2 Main Protease by Deep Docking of 1 3?Billion Compounds
32379955 ä. Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
32375002 ä. Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery
| 32378459 2020. Application of nanomaterials in treatment, anti-infection and detection of coronaviruses |
| 32363750 2020. A Chemographic Audit of anti-Coronavirus Structure-Activity Information from Public Databases (ChEMBL) |
32369286 2020. A Trial of Lopinavir-Ritonavir in Covid-19 Reply
32227757 2020. Developing Covid-19 Vaccines at Pandemic Speed
32289216 2020. Drug Evaluation during the Covid-19 Pandemic
32332765 2020. Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig
32273604 2020. Lopinavir-ritonavir in severe COVID-19
32273591 2020. The COVID-19 vaccine development landscape
32269311 2020. Coordinating the COVID-19 pipeline
32127666 2020. Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
32376938 2020. China is promoting coronavirus treatments based on unproven traditional medicines
32272481 2020. Structure of M(pro) from SARS-CoV-2 and discovery of its inhibitors
32350436 2020. Hopes rise for coronavirus drug remdesivir
32355243 2020. Scores of coronavirus vaccines are in competition - how will scientists choose the best?
32353859 2020. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
32300225 2020. On the front lines of the coronavirus-vaccine battle
32346146 2020. The race for coronavirus vaccines: a graphical guide
32377399 2020. COVID-19 vaccines: breaking record times to first-in-human trials
32297843 2020. Oligonucleotides and the COVID-19 Pandemic: A Perspective
32380200 ä. In Silico Design of Antiviral Peptides Targeting the Spike Protein of SARS-CoV-2
32275178 2020. Harnessing innate immunity to eliminate SARS-CoV-2 and ameliorate COVID-19 disease
32216577 2020. Artificial intelligence and machine learning to fight COVID-19
32380051 ä. The clinical benefits of Chinese patent medicines against COVID-19 based on current evidence
32352615 2020. Povidone-iodine gargle as a prophylactic intervention to interrupt the transmission of SARS-CoV-2
32209313 2020. New therapeutic opportunities for COVID-19 patients with Tocilizumab: Possible correlation of interleukin-6 receptor inhibitors with osteonecrosis of the jaws
32285489 2020. Chloroquine and Hydroxychloroquine in the Era of SARS - CoV2: Caution on Their Cardiac Toxicity
32267566 2020. Therapeutic Potential for Tetracyclines in the Treatment of COVID-19
32267560 2020. Considerations for Statin Therapy in Patients with COVID-19
32259313 2020. Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019
32281114 2020. Delayed Initiation of Remdesivir in a COVID-19-Positive Patient
32296012 2020. Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia
32295694 2020. COVID-19 vaccination clinical trials should consider multiple doses of BCG
32326830 2020. Photobiomodulation and Antiviral Photodynamic Therapy as a Possible Novel Approach in COVID-19 Management
32330404 2020. Can Transdermal Photobiomodulation Help Us at the Time of COVID-19?
32352594 2020. Phytotherapic compounds against coronaviruses: Possible streams for future research
32347602 2020. Should we try the antiinflammatory natural product, celastrol, for COVID-19?
32350134 2020. Effective treatment of severe COVID-19 patients with tocilizumab
32365207 ä. Combined treatment of tocilizumab and chloroquine on severe COVID-19: a case report
32314850 2020. Melatonin: Roles in influenza, Covid?19, and other viral infections
32374874 ä. COVID-19: an unexpected indication for anti-rheumatic therapies?
32376603 ä. Development of an inactivated vaccine candidate for SARS-CoV-2
32352871 2020. A Radiation Mitigator as a Potential Treatment for COVID-19
32273254 2020. Cannabidiol as prophylaxis for SARS-CoV-2 and COVID-19? Unfounded claims versus potential risks of medications during the pandemic
32167254 2020. Epidemie de coronavirus et polemique sur la chloroquine
32270942 2020. Covid-19, dans les brouillards francais de l'hydroxychloroquine
32301315 2020. Covid-19, dans les brouillards de l'hydroxychloroquine (2)
32301312 2020. Vaccins anti-covid-19 : les recherches de johnson & johnson, sanofi et pasteur
32355008 2020. COVID-19 shot protects monkeys
32292113 2020. Stem Cell?Based Therapy for Coronavirus Disease 2019
32272857 2020. Role of Tissue Engineering in COVID-19 and Future Viral Outbreaks
32360327 ä. Potential repurposing of Favipiravir in COVID-19 outbreak based on current evidence
32302280 2020. Brief Summary of Potential SARS-CoV-2 Prophylactic and Treatment Drugs in the Emergency Department
32220178 2020. Biological Product Development Strategies for Prevention and Treatment of Coronavirus Disease 2019
32374891 2020. Convalescent plasma to treat coronavirus disease 2019 (COVID-19): considerations for clinical trial design
32374890 2020. COVID-19 convalescent plasma: phase 2
32245869 2020. Possible treatment of Covid-19 with a therapeutic vaccine
32221001 2020. Possible method for the production of a Covid-19 vaccine
32324899 2020. Operational protocol for donation of anti-COVID-19 convalescent plasma in Italy
32319102 2020. Points to consider in the preparation and transfusion of COVID-19 convalescent plasma
32240545 2020. Collecting and evaluating convalescent plasma for COVID-19 treatment: why and how?
32268018 2020. Analysis of medication characteristics of traditional Chinese medicine in treating coronavirus disease-19 based on data mining
32281335 2020. Research progress of intervention of Chinese herbal medicine and its active components on human coronavirus
32281333 2020. Analysis of property and efficacy of traditional Chinese medicine in staging revention and treatment of coronavirus disease 2019
32281332 2020. Study on medication regularity of traditional Chinese medicine in treatment of COVID-19 based on data mining
32281331 2020. Analysis on pattern of prescriptions and syndromes of traditional Chinese medicine for prevention and treatment of COVID-19
32281330 2020. Analysis on clinical study protocols of traditional Chinese medicine for coronavirus disease 2019
| 32281329 2020. Study on treatment of "cytokine storm" by anti-2019-nCoV prescriptions based on arachidonic acid metabolic pathway |
32281328 2020. Study on screening potential traditional Chinese medicines against 2019-nCoV based on Mpro and PLP
32281327 2020. Rapid establishment of traditional Chinese medicine prevention and treatment of 2019-nCoV based on clinical experience and molecular docking
32164085 2020. Expert consensus on chloroquine phosphate for the treatment of novel coronavirus pneumonia
32164084 2020. Expert consensus on the use of corticosteroid in patients with 2019-nCoV pneumonia
32164080 2020. Potential antiviral therapeutics for 2019 Novel Coronavirus
32164081 2020. Pharmacotherapeutics for the new coronavirus pneumonia
32164077 2020. Pharmacotherapeutic about the new coronavirus pneumonia
32114746 2020. Drug interaction monitoring of lopinavir/ritonavir in COVID-19 patients with cancer
32234130 2020. Progress and challenge of vaccine development against 2019 novel coronavirus (2019-nCoV)
C7203037 ä. (Vitamin-C; Ozone)Two known therapies could be useful as adjuvant therapy in critical patients infected by COVID-19?
C7197234 2020. Safety concerns with higher dosage chloroquine in COVID-19 patients
C7197245 2020. Antimalarial use in COVID-19 patients requires close monitoring
C7180667 ä. Achilles heel of the killer virus: the highly important molecular targets for hitting SARS-CoV-2 that causes COVID-19
C7190525 2020. Adjunct Immunotherapies for the Management of Severely Ill COVID-19 Patients
C7152890 2020. Biomimetic nanoparticles as universal influenza vaccine
C7149307 ä. Die Anwendung der Traditionellen Chinesischen Medizin...
C7144855 ä. Protocolo de diagn�stico y tratamiento para COVID-19 mediante medicina tradicional china?
32292907 2020. Standing out from the crowd in treating COVID-19 the title has been idioted from Potential TRPV1 blockade to treat severe lung dysfunction in COVID-19 infection.
C7187737 ä. COVID-19 and the Rationale for Pharmacotherapy: A South African Perspective
C7167691 2020. (Deutsche Szene) Schutz vor und Hilfe bei Covid19 Infektionen
C7149252 2020. Traditionelle Chinesische Medizin ... Ein Bericht aus Wuhan...
32483554 ä. Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
32377965 ä. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality
C7189003 2020. Glukokortikoide und Covid-19
C7189010 2020. Biologika und Covid-19
C7162107 2020. Chloroquin gegen Corona?
C7187784 ä. Case Study: A Patient with Asthma, Covid-19 Pneumonia and Cytokine Release Syndrome Treated with Corticosteroids and Tocilizumab
32387535 ä. Asthma, biologics, corticosteroids, and coronavirus disease 2019
| C7197610 ä. Isolation of a human monoclonal antibody specific for the receptor binding domain of SARS-CoV-2 using a competitive phage biopanning strategy |
C7197606 ä. Antibody therapies for the treatment of COVID-19
32376396 2020. Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia?
32380316 2020. Convalescent plasma in Covid-19: Possible mechanisms of action
32380318 2020. Why judiciously timed anti-IL 6 therapy may be of benefit in severe COVID-19 infection
32380315 2020. Continuous hydroxychloroquine or colchicine therapy does not prevent infection with SARS-CoV-2: Insights from a large healthcare database analysis
32376392 2020. Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
32387040 ä. Sofosbuvir as Repurposed Antiviral Drug Against COVID-19: Why Were We Convinced to Evaluate the Drug in a Registered/Approved Clinical Trial?
32389697 ä. Plasmapheresis treatment in COVID-19?related autoimmune meningoencephalitis: Case series
32475597 2020. The important role of polysaccharides from a traditional Chinese medicine-Lung Cleansing and Detoxifying Decoction against the COVID-19 pandemic
32437659 2020. Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection
| 32402856 2020. Could an endo-lysosomal ion channel be the Achilles heel of SARS-CoV2? |
| 32231345 ä. Inhibition of SARS-CoV-2 infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion |
32376238 2020. (rev on nat.prod.pharmacophores)Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective
32391065 2020. Traditional Chinese medicine contributes to the treatment of COVID-19 patients
32402416 ä. Perforacion intestinal en paciente COVID-19 en tratamiento con tocilizumab y corticoides ...
C7186126 ä. Proposed use of thalidomide for the cytokine storm of COVID-19
32379639 2020. Herbal medicine for treatment of children diagnosed with COVID-19: A review of guidelines
32379692 2020. Traditional Chinese Medicine treatment of COVID-19
C7151553 2020. COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles? heel conserved region to minimize probability of escape mutations and drug resistance
32129977 2020. Cell-Membrane-Mimicking Nanodecoys against Infectious Diseases
29115746 2018. Progress Toward the Clinical Translation of Bioinspired Peptide and Protein Assemblies
29717819 2018. Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens
28945945 2017. Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses
32205350 2020. Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses
21093489 2011. (x)Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse model
20727913 2010. (x)Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus
16621037 2006. (x)Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin
31073993 2019. (x)Synthesis and anti?coronavirus activity of a series of 1?thia?4?azaspiro 4 5 decan?3?one derivatives
32223926 2020. Remdesivir attenuates high fat diet (HFD)-induced NAFLD by regulating hepatocyte dyslipidemia and inflammation via the suppression of STING
32285908 2020. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling
| 32315397 2020. Promoting platelets is a therapeutic option to combat severe viral infection of the lung |
32243785 2020. Embracing the Landscape of Therapeutics
| 32313209 ä. Chloroquine reduces Th17 cell differentiation by stimulating T-bet expression in T cells |
17806092 2008. Ferrocene Conjugates of Chloroquine and other Antimalarials: the Development of Ferroquine, a New Antimalarial
30993690 2019. Emerging viruses and current strategies for vaccine intervention
23607598 2013. (x)Involvement of high mobility group box 1 and the therapeutic effect of recombinant thrombomodulin in a mouse model of severe acute respiratory distress syndrome
32099652 2020. Frontiers in antiviral therapy and immunotherapy
| 32321563 2020. IL6-R blocking with tocilizumab in critically ill patients with hemophagocytic syndrome |
32259744 2020. DNA vaccines: prime time is now
32387642 2020. Innovations in structure-based antigen design and immune monitoring for next generation vaccines
C7163352 ä. Cell-Based Therapies for COVID-19: Proper Clinical Investigations are Essential
32382358 ä. COVID-19 and Diabetes Mellitus: May Old Anti-diabetic Agents Become the New Philosopher?s Stone?
32377559 ä. COVID-19: Review of Epidemiology and Potential Treatments Against 2019 Novel Coronavirus
32387262 ä. Extracellular vesicles from mesenchymal stem cells as a Covid-19 treatment
C7194243 ä. Coronavirus Disease 2019 (COVID-19) Spread and Pharmacovigilance Implications: Expert Opinion
32383008 ä. The Role of Pharmacovigilance and ISoP During the Global COVID-19 Pandemic
32344202 2020. Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development
32387014 ä. Repositionnement de la chlorpromazine ... psychiatric patients could be protected from severe forms of COVID-19 by their psychotropic treatments
C7118608 ä. A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification System
32292529 2020. Highlights of traditional Chinese medicine frontline expert advice in the China national guideline for COVID-19
32381323 ä. Acute hemolysis by hydroxycloroquine was observed in G6PD-deficient patient with severe COVD-19 related lung injury
C7117595 ä. Drug repurposing strategies for COVID-19
32348877 ä. Chemical evolution for taming the ?pathogenic kinase? PAK1
16022774 2005. (+)SARS Vaccine Development
28861908 2017. (+)Issues in vaccinology: Present challenges and future directions
31931639 2020. Dapsone as treatment adjunct in ARDS
16433589 2006. (+)Antiviral applications of RNAi for coronavirus
32318055 2020. Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools
32362826 2020. Editorial: New Advances in RNA Targeting
32201439 2020. Therapeutic options for the treatment of 2019-novel coronavirus: An evidence-based approach
32298965 2020. Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate
32081774 2020. Discovery and development of safe-in-man broad-spectrum antiviral agents
32380291 ä. Chloroquine-induced torsades de pointes in a patient with coronavirus disease 2019
32387130 ä. GTS-21, an alpha7nAChR agonist, suppressed the production of key inflammatory mediators by PBMCs that are elevated in COPD patients and associated with impaired lung function
C7184982 ä. Ventricular arrhythmia risk due to chloroquine / hydroxychloroquine treatment for COVID-19: Should it be given
| 32389720 ä. Excessive lysosomal ion-trapping of hydroxychloroquine and azithromycin |
32389721 ä. Tocilizumab in COVID-19: Beware the risk of intestinal perforation
32294495 ä. Chloroquine as a prophylactic agent against COVID-19?
32386655 2020. Influence of immune aging on vaccine responses
32376368 2020. Identifying potential treatments of COVID-19 from Traditional Chinese Medicine (TCM) by using a data-driven approach
32451138 ä. ...surveillance ophtalmologique ...hydroxychloroquine e...
32446813 ä. Diagnosis and treatment of novel coronavirus pneumonia based on the theory of traditional Chinese medicine
32277065 2020. Halting coronavirus polymerase
32336762 2012. Design of Angiotensin?converting Enzyme 2 (ACE2) Inhibitors by Virtual Lead Optimization and Screening
32281318 2020. Convalescent Plasma Therapy for Corona Virus Disease 2019: a Long Way to Go but Worth Trying
32045235 ä. ?-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
32105468 2020. Structure-Based Stabilization of Non-native Protein?Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design
27905101 2017. (+)A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms
16697221 2006. (+)Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus
| 31856018 2020. Is there a role for tissue plasminogen activator as a novel treatment for refractory COVID-19 associated acute respiratory distress syndrome? |
32388486 2020. Light as a potential treatment for pandemic coronavirus infections: A perspective
C7154570 2020. Anti-IL6R role in treatment of COVID-19-related ARDS
32423584 2020. Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
32423580 2020. Remdesivir for COVID-19: challenges of underpowered studies
C7202831 ä. Testing COVID-19 therapies to prevent progression of mild disease
C7202844 ä. Vaccine development during global epidemics: the Zika experience
32380023 ä. Immunomodulation in COVID-19
32444269 ä. Immunotherapies for COVID-19: lessons learned from sepsis
32409074 2020. An overview of functional nanoparticles as novel emerging antiviral therapeutic agents
C7190528 ä. Treatment Considerations for COVID-19: A Critical Review of the Evidence (or Lack Thereof)
32386744 ä. Uso de antipaludicos (antimalarials)...
32408073 2020. Lithium for the 2019 novel coronavirus
32416413 2020. Covid-19 management with inflammation resolving mediators? Perspectives and potential
32408070 2020. Does zinc supplementation enhance the clinical efficacy of chloroquine/hydroxychloroquine to win todays battle against COVID-19?
32373787 2020. A new paradigm for drug development
32359447 2020. The resurgence of convalescent plasma therapy
32325038 ä. (+)Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial
32325036 ä. Two Middle East respiratory syndrome vaccines: first step for other coronavirus vaccines?
| 29329956 2018. Herd immunity: hyperimmune globulins for the 21st century |
31351923 2019. (+)First clinical trial of a MERS coronavirus DNA vaccine
28664850 2017. (+)Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome
32373790 2020. Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome
29852530 2020. The expanding role of mass spectrometry in the field of vaccine development
31432544 2020. Repurposing approved drugs on the pathway to novel therapies
31692019 2020. (+)Gold nanoparticle?adjuvanted S protein induces a strong antigen?specific IgG response against severe acute respiratory syndrome?related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs
24773578 2014. Chloroquine interferes with dengue?2 virus replication in U937 cells
32197324 2020. A Review on Applications of Computational Methods in Drug Screening and Design
20956884 2010. (+)Small Interfering RNA Effectively Inhibits the Expression of SARS Coronavirus Membrane Gene at Two Novel Targeting Sites
32317764 ä. Developing therapeutic monoclonal antibodies at pandemic pace
32286537 ä. Hydroxychloroquine: small effects in mild disease
32408071 2020. Relation between BCG coverage rate and COVID-19 infection worldwide
C7136957 ä. Is Global BCG Vaccination Coverage Relevant To The Progression Of SARS-CoV-2 Pandemic?
32388480 2020. Can beta-adrenergic blockers be used in the treatment of COVID-19?
32388476 2020. Is copper beneficial for COVID-19 patients?
32402766 2020. Hydroxychloroquine as an aerosol might markedly reduce and even prevent severe clinical symptoms after SARS-CoV-2 infection
32387756 2020. SARS ? CoV-2: Reasons of epidemiology of severe ill disease cases and therapeutic approach using trivalent vaccine (tetanus, diphtheria and Bordetella pertussis)
32438240 2020. 5-Fluorouracil in combination with deoxyribonucleosides and deoxyribose as possible therapeutic options for the Coronavirus, COVID-19 infection
32387320 ä. Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients
32387333 ä. Could nasal nitric oxide help to mitigate the severity of COVID-19?
32387334 ä. The Forrest Gump approach to preventing severe COVID-19 ? reverse the predisposing pro-inflammatory state with exercise
32376359 2020. Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2
32380958 2020. Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19?
32382315 2020. Can graphene take part in the fight against COVID-19?
32313660 2020. A short review on antibody therapy for COVID-19
32377399 2020. COVID-19 vaccines: breaking record times to first-in-human trials
32380200 2020. In silico design of antiviral peptides targeting the spike protein of SARS-CoV-2
32380051 2020. The clinical benefits of Chinese patent medicines against COVID-19 based on current evidence
32380052 2020. Granulocyte-targeted therapies for airway diseases
32389754 ä. (low dose radiat)RILI model and the Covid-19 pneumonia: The radiation oncologist point of view?
32387544 ä. Response to: Low dose radiation therapy for COVID-19 pneumonia a double-edged sword?
32409150 ä. An evaluation of co-use of chloroquine or hydroxychloroquine plus azithromycin on cardiac outcomes: A pharmacoepidemiological study to inform use during the COVID19 pandemic
32482538 ä. Propuesta de uso de anakinra en el distr�s respiratorio agudo secundario a COVID-19
32253226 ä. (NHC, EIDD-1931) An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
32418730 ä. ?Off-label? use of hydroxychloroquine, azithromycin, lopinavir-ritonavir and chloroquine in COVID-19: A survey of cardiac adverse drug reactions by the French Network of Pharmacovigilance Centers
32448638 2020. Convalescent plasma, an apheresis research project targeting and motivating the fully recovered COVID 19 patients: A rousing message of clinical benefit to both donors and recipients alike
32417123 ä. Convalescent plasma, an apheresis research project targeting and motivating the fully recovered COVID 19 patients: A rousing message of clinical benefit to both donors and recipients alike
32387409 ä. Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France
32387694 ä. Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review
32418793 2020. An effective CTL peptide vaccine for Ebola Zaire Based on Survivors? CD8+ targeting of a particular nucleocapsid protein epitope with potential implications for COVID-19 vaccine design
32381478 2020. Enabling emergency mass vaccination: Innovations in manufacturing and administration during a pandemic
32452420 2020. Antiviral activity of lycorine against Zika virus in vivo and in vitro
32292259 2020. Understanding of guidance for acupuncture and moxibustion interventions on COVID-19 (Second edition) issued by CAAM
32331804 ä. Hydroxychloroquine and ?off-label? utilization in the treatment of oral conditions
32061923 2020. Dipeptidyl peptidase 4 inhibitors and their potential immune modulatory functions
32289478 2020. Statins in coronavirus outbreak: It?s time for experimental and clinical studies
28596841 2017. Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases
32208449 2020. BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses
32355446 2020. Medicaments rhumatologiques pour le traitement de l?infection par le COVID-19?
32077621 2020. Glycyrrhizic?Acid?Based Carbon Dots with High Antiviral Activity by Multisite Inhibition Mechanisms
16043204 2005. (+)Long-term protection from SARS coronavirus infection conferred by a single immunization with an attenuated VSV-based vaccine
31930543 2020. Inactivation of three emerging viruses ? severe acute respiratory syndrome coronavirus, Crimean?Congo haemorrhagic fever virus and Nipah virus ? in platelet concentrates by ultraviolet C light and in plasma by methylene blue plus visible light
