Candidate Compounds Covid19

Version vom 18. Juni 2020, 11:28 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

current items will be put into the subsections. subsections with contents are marked with content. the others are pending data.

• reviews on covid drug development with content

• Patients on biologicals
• HMGB1, RAGE
• pre-Interleukin 6 with content
• post-Interleukin 6
• pre-TNFalpha
• post-TNFalpha
• pre-Interleukin 17
• post-Interleukin 17
• pre-Interleukin 1
• post-Interleukin 1
• Inflammasome

• NK-kappaB
• STAT 3
• JAK Janus Kinase
• Corticosteroids
• Cytokine absorbers
• Target Complement system
• Target Extracellular traps
• Anticoagulant in covid19
• Antioxidants
• Stem cells
• MDSC cells

• other single compounds
• Retargeted single compounds
• Hydroxychloroquine with content

• other antiviral compounds
• AV Remdesivir
• AV Lopinavir
• AV Ivermectin

• Target ACE2, Spike protein
• Target TMPRSS2, Spike protein

• Interferons

• Vitamin D

• Statins
• Anorganic nutrients Magnesium
• Anorganic nutrients Selenium
• Anorganic nutrients Zinc

• Traditional Chinese Medicine
• Natural compounds

• Reconvalescent blood products, Passive vaccine with content
• Plasmapheresis

• Immunodeviation e.g. by adjuvants or other vaccinations
• Active vaccine with cotent

32162456 2020. Rapid Identification of Potential Inhibitors of SARS-CoV-2 Main Protease by Deep Docking of 1 3 Billion Compounds

Microbiome as target
32356654 ä. Considering the Effects of Microbiome and Diet on SARS-CoV-2 Infection: Nanotechnology Roles

stem cells
32257554 2020. Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia
32257537 2020. Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia
32283815 2020. Mesenchymal Stromal Cell Secretome for Severe COVID-19 Infections: Premises for the Therapeutic Use

32241793 2020. Clinical course of COVID-19 in a series of patients with chronic arthritis treated with immunosuppressive targeted therapies

CRISPR genome editing technology
32353252 ä. Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza

Virus interference
32071427 2020. Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses

resilience enhancement
32229705 2020. Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections
32311498 ä. The impact of nutrition on COVID-19 susceptibility and long-term consequences
32276453 2020. Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats

psychoneuroimmunology
32234338 ä. Using psychoneuroimmunity against COVID-19

Exercise
32311497 ä. The immunological case for staying active during the COVID-19 pandemic

Topical agents opening up the world of nano...

• on mouth rinses

32247038 2020. Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19
32222466 2020. The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China

32266375 ä. Inquiring into Benefits of Independent Activation of Non-Classical Renin-Angiotensin System in the Clinical Prognosis and Reduction of COVID-19 mortality

32305181 ä. ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection
32360083 ä. Modulation of Hb-O2 affinity to improve hypoxemia in COVID-19 patients

32277367 ä. Rheumatologists? perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets
32373721 2020. Low dose lung radiotherapy for COVID-19 pneumonia The rationale for a cost-effective anti-inflammatory treatment

32241301 2020. A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19

32318324 ä. Depriving Iron Supply to the Virus Represents a Promising Adjuvant Therapeutic Against Viral Survival

32360420 ä. Cytokine storm intervention in the early stages of COVID-19 pneumonia

32335366 2020. Can dapagliflozin have a protective effect against COVID-19 infection? A hypothesis
32333972 ä. Letter to the Editor in response to the article ?COVID-19 and diabetes: Can DPP4 inhibition play a role??
32333966 2020. COVID-19 and diabetes: Is this association driven by the DPP4 receptor? Potential clinical and therapeutic implications
32333969 ä. Response to COVID -19 and Diabetes: Can DPP4 Inhibition Play a Role? ? GLP-1 Might Play One Too
32283128 ä. Should anti-diabetic medications be reconsidered amid COVID-19 pandemic? on ace2 via adam17, nfkb via dpp4

32325124 ä. Vaporization, bioactive formulations and a marine natural product: different perspectives on antivirals

32249203 ä. Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

32333818 2020. COVID-19: lambda interferon against viral load and hyperinflammation

32228222 2020. Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension

C7118608 ä. A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification System
32065055 2020. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

32292627 ä. Clinical study of mesenchymal stem cell treating acute respiratory distress syndrome induced by epidemic Influenza A (H7N9) infection, a hint for COVID-19 treatment

32347925 ä. Statin therapy in COVID-19 infection

32337546 ä. Colchicine as a potent anti-inflammatory treatment in COVID-19: can we teach an old dog new tricks?
32282032 ä. Neprilysin inhibitor?angiotensin II receptor blocker combination (sacubitril/valsartan): rationale for adoption in SARS-CoV-2 patients
32285293 ä. Searching therapeutic strategy of new coronavirus pneumonia from angiotensin-converting enzyme 2: the target of COVID-19 and SARS-CoV

32265310 ä. Current Status of Cell-Based Therapies for Respiratory Virus Infections: Applicability to COVID-19
32271462 2020. Inositol and pulmonary function Could myo-inositol treatment downregulate inflammation and cytokine release syndrome in SARS-CoV-2?

32329380 2020. Adipose-derived stromal stem cells (ASCs) as a new regenerative immediate therapy combating coronavirus (COVID-19)-induced pneumonia
32312129 2020. The role of additive manufacturing and antimicrobial polymers in the COVID-19 pandemic
32117569 2020. Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China

32251729 ä. The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design

32247692 ä. Faecal-oral transmission of SARS-COV-2: practical implications
32367287 ä. New evidence of SARS-CoV-2 transmission through the ocular surface

32251365 ä. Considering mutational meltdown as a potential SARS-CoV-2 treatment strategy

32186952 2020. COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics

32366728 2020. Medical Education During the COVID-19 Pandemic: A Single Institution Experience
32366726 2020. Management of Asthma in Children during COVID-19 Pandemic
32366725 2020. COVID -19 Pandemic: The Challenges for Pediatric Oncology

32341599 2020. Is Immuno-modulation the Key to COVID-19 Pandemic?

32328406 ä. Vaccines for SARS-CoV-2: Lessons from Other Coronavirus Strains

32272396 ä. The Possible of Immunotherapy for COVID-19: a Systematic Review

32234466 ä. Coronavirus disease 2019 (COVID-19): current status and future perspectives

32283177 ä. Coronavirus (COVID-19), First Indication of Efficacy of Gene-Eden-VIR/Novirin in SARS-CoV-2 Infections

32226290 2020. Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19

• Oxford vaccine failed in monkeys

32305009 ä. Investigating hypothiocyanite against SARS-CoV-2

32354030 2020. Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work

32368489 2020. The pathogenesis and alternative treatment of SARS-CoV2

• Nature: The COVID-19 vaccine development landscape

32336674 ä. COVID-19 Emergency Responders in FDA?s Center for Drug Evaluation and Research

32317220 ä. The anti-viral facet of anti-rheumatic drugs: Lessons from COVID-19

32326602 2020. Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19
32326426 2020. COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression

32359878 2020. Application of plasma exchange in association with higher dose CVVH in Cytokine Storm Complicating COVID-19

32171450 2020. Identification of potential cross-protective epitope between a new type of coronavirus (2019-nCoV) and severe acute respiratory syndrome virus

32373322 ä. Fighting COVID-19 with water dehydration of mucous glycans

32293807 2020. Systematic review of the efficacy and safety of antiretroviral drugs against SARS, MERS or COVID?19: initial assessment

32356252 ä. COVID-19: Therapeutics and Their Toxicities
32356251 ä. Medical Toxicology and COVID-19: Our Role in a Pandemic
32052466 2020. Potential interventions for novel coronavirus in China: A systematic review

32346490 ä. Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase
32324533 2020. Prevention and therapy of COVID-19 via exogenous estrogen treatment for both male and female patients

32291198 2020. Impact of Nutrition and Diet on COVID-19 Infection and Implications for Kidney Health and Kidney Disease Management

32321635 2020. Old and new antirheumatic drugs for the treatment of COVID-19

32317113 2020. COVID-19 therapeutic options for patients with kidney disease

32035018 2020. Reducing mortality from 2019-nCoV: host-directed therapies should be an option

32220278 2020. Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?
32353328 2020. What policy makers need to know about COVID-19 protective immunity
32305088 2020. Flooded by the torrent: the COVID-19 drug pipeline

32339473 ä. Probiotics and COVID-19: one size does not fit all
32199468 ä. Use of antiviral drugs to reduce COVID-19 transmission
32278361 ä. Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19

32325035 ä. Plea for multitargeted interventions for severe COVID-19
32113510 2020. Convalescent plasma as a potential therapy for COVID-19
32113509 2020. COVID-19: combining antiviral and anti-inflammatory treatments
32368737 2020. Preventing COVID-19-induced pneumonia with anticytokine therapy

32278693 2020. In silico studies on therapeutic agents for COVID-19: Drug repurposing approach

32198163 2020. Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection
32265331 2020. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

32296777 2020. Mesenchymal stem cells and management of COVID-19 pneumonia
32289117 2020. Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus

32292909 2020. Target Virus or Target Ourselves for COVID-19 Drugs Discovery?-Lessons learned from anti-influenzas virus therapies
32220710 2020. Renin-angiotensin system: The unexpected flaw inside the human immune system revealed by SARS-CoV-2

• riociguat?

32353740 2020. Serum albumin-mediated strategy for the effective targeting of SARS-CoV-2

32344313 ä. Can pioglitazone be potentially useful therapeutically in treating patients with covid-19?
32344312 2020. Potential effect of natural and anabolizan steroids in elderly patient with COVID-19
32344310 2020. Respiratory conditions in coronavirus disease 2019 (COVID-19): Important considerations regarding novel treatment strategies to reduce mortality

32339777 2020. May IL-17 have a role in COVID-19 infection?
32335456 2020. The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases?

C7158785 ä. Convalescent plasma: A possible treatment of COVID-19 in India
32353355 ä. Testosterone, a key hormone in the context of COVID-19 pandemic
32370766 2020. Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines
32307014 2020. Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19
32255312 2020. A possible probiotic (S salivarius K12) approach to improve oral and lung microbiotas and raise defenses against SARS-CoV-2
32365556 2020. Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-gamma as Candidates for Cytokine Storm Modulation in COVID-19 Disease
32231348 2020. Emerging prophylaxis strategies against COVID-19

32187463 ä. Covid-19 ? The Search for Effective Therapy

32354113 2020. On Facing the SARS-CoV-2 (COVID-19) with Combination of Nanomaterials and Medicine: Possible Strategies and First Challenges
32326343 2020. Can Nanotechnology and Materials Science Help the Fight against SARS-CoV-2?

32203437 ä. Insights from nanomedicine into chloroquine efficacy against COVID-19

32296135 ä. COVID-19: risk for cytokine targeting in chronic inflammatory diseases?
32355330 ä. Inactivated vaccine for SARS-CoV-2

32346092 ä. Cancer therapy tool informs COVID-19 vaccines
32346094 ä. COVID-19 vaccine design: the Janus face of immune enhancement
32317716 ä. The potential danger of suboptimal antibody responses in COVID-19

• A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

32341531 ä. Could BCG be used to protect against COVID-19?
32291449 ä. ADAM17 inhibition may exert a protective effect on COVID-19
32350818 ä. Chloroquine-induced QTc prolongation in COVID-19 patients

• dextrometorphan (antitussive compd)

32322402 2020. Review on the global epidemiological situation and the efficacy of chloroquine and hydroxychloroquine for the treatment of COVID-19
32355564 2020. Consideration of dornase alfa for the treatment of severe COVID-19 acute respiratory distress syndrome
32322397 2020. Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: trends, scope and relevance
32313660 2020. A short review on antibody therapy for COVID-19
32372835 2020. Trials of BCG vaccine will test for covid-19 protection
32287799 2020. Drug trials under way
32353120 ä. Does Cigarette Smoking Protect Against SARS-CoV-2 Infection?
32242236 ä. COVID-19 and Smoking
32194995 2020. The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines
32340216 2020. Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections
32252338 2020. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths
32342019 ä. Exercise against SARS-CoV-2 (COVID-19): Does workout intensity matter? (A mini review of some indirect evidence related to obesity)
32258351 2020. Current knowledge about the antivirals remdesivir (GS-5734) and GS-441524 as therapeutic options for coronaviruses
32258207 2020. High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019
32363212 ä. Review: Hydroxychloroquine and Chloroquine for Treatment of SARS-CoV-2 (COVID-19)
32292817 2020. Coalition: Advocacy for prospective clinical trials to test the post-exposure potential of hydroxychloroquine against COVID-19
32284951 2020. Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options
32214286 2020. Expanded Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) as a Therapeutic Strategy in Managing Critically Ill COVID-19 Patients: The Case for Compassionate Use
32098302 2020. Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development
32357471 2020. Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
32333199 ä. Coronavirus in Hematologic Malignancies: Targeting Molecules Beyond the Angiotensin-Converting Enzyme 2 (ACE2) Wall in COVID-19
32307559 ä. Management for patients with pediatric surgical disease during the COVID-19 epidemic
32215760 2020. Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond
32245264 2020. Emetine, Ipecac, Ipecac Alkaloids and Analogues as Potential Antiviral Agents for Coronaviruses
32290348 2020. COVID-19: A Brief Overview of the Discovery Clinical Trial
32371086 ä. The pros and cons of traditional Chinese medicines in the treatment of COVID-19
32145402 2020. Traditional Chinese medicine for COVID-19 treatment
32205232 2020. Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)
32360585 ä. Current targeted therapeutics against COVID-19: based on first-line experience in china
32360584 ä. Possible use of the mucolytic drug, bromhexine hydrochloride, as a prophylactic agent against SARS-CoV-2 infection based on its action on the Transmembrane Serine Protease 2
32360583 ä. Efficacy and safety of current therapeutic options for COVID-19 - lessons to be learnt from SARS and MERS epidemic: A systematic review and meta-analysis
32360581 ä. Nitazoxanide/Azithromycin combination for COVID-19: A suggested new protocol for COVID-19 early management
32360580 ä. Liu Shen capsule shows antiviral and anti-inflammatory abilities against novel coronavirus SARS-CoV-2 via suppression of NF-kappaB signaling pathway
32251726 2020. The use of Traditional Chinese Medicines to treat SARS-CoV-2 may cause more harm than good
32251725 ä. Reply to ?The use of traditional Chinese medicines to treat SARS-CoV-2 may cause more harm than good?
32360484 2020. Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study
32360480 ä. Candidate drugs against SARS-CoV-2 and COVID-19
32334052 2020. Repurposing the mucolytic cough suppressant and TMPRSS2 protease inhibitor bromhexine for the prevention and management of SARS-CoV-2 infection
32325127 2020. Darunavir does not prevent SARS-CoV-2 infection in HIV patients
32247821 2020. 3CLpro inhibitors as a potential therapeutic option for COVID-19: Available evidence and ongoing clinical trials
32302707 ä. Could IL-17 represent a new therapeutic target for the treatment and/or management of COVID-19-related respiratory syndrome?: This paper is dedicated to Sofia Maione born during COVID-19 outbreak
32283223 2020. Plausibility of therapeutic effects of Rho kinase inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19)
32322486 2020. Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome
32369479 2020. Antibody-based therapies for COVID-19: Can Europe move faster?
32343686 2020. Pandemic responses: Planning to neutralize SARS-CoV-2 and prepare for future outbreaks

32054787 2020. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
32253318 2020. Effectiveness of convalescent plasma therapy in severe COVID-19 patients
32229574 2020. News Feature: Avoiding pitfalls in the pursuit of a COVID-19 vaccine
32275753 ä. Plasminogen improves lung lesions and hypoxemia in patients with COVID-19
32342871 ä. Is low dose radiation therapy a potential treatment for COVID-19 pneumonia?
32342874 ä. Low dose radiation therapy for COVID-19 pneumonia: a double-edged sword
32327397 ä. Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine

32354685 ä. Why choose cyclosporin A as first-line therapy in COVID-19 pneumonia

32239125 2020. Remdesivir, la esperanza antiviral frente al SARS-CoV-2
32256547 2020. Clinical trials on drug repositioning for COVID-19 treatment
32267301 ä. Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
32232552 ä. Coronavirus disease 2019 (COVID-19) and anti-rheumatic drugs
32124179 ä. Clinical trials for the treatment of Coronavirus disease 2019 (COVID-19): A rapid response to urgent need
32376987 2020. Inhibition of Influenza A virus propagation by benzoselenoxanthenes stabilizing TMPRSS2 Gene G-quadruplex and hence down-regulating TMPRSS2 expression
32278175 ä. COVID-19: A promising cure for the global panic
32253226 ä. (β-D-N4-hydroxycytidine (NHC, EIDD-1931) An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
32358203 ä. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
32198291 2020. Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved ?-ketoamide inhibitors
32321856 ä. Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
32347055 2020. Role of cyclophilin A during coronavirus replication and the antiviral activities of its inhibitors
32341331 2020. A retrospective cohort study of methylprednisolone therapy in severe patients with COVID-19 pneumonia
32347054 2020. Strategies for vaccine development of COVID-19
32133159 2020. Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia
32366290 2020. Mesenchymal stem cells as a potential therapy for COVID-19
C7110269 ä. COVID-19 Outbreak: an Update on Therapeutic Options
32307653 ä. CD147 as a Target for COVID-19 Treatment: Suggested Effects of Azithromycin and Stem Cell Engagement
32281052 ä. Mesenchymal Stem Cell Therapy for COVID-19: Present or Future
32320535 2020. Mesenchymal stem cells as a potential treatment for critically ill patients with coronavirus disease 2019
32362735 ä. Insights into the inhibitory potential of selective phytochemicals against Mpro of 2019-nCoV: a computer-aided study
32347963 2020. An independent appraisal and re-analysis of hydroxychloroquine treatment trial for COVID-19
32343358 2020. Immunoglobulins or convalescent plasma to tackle COVID-19: buying time to save lives - current situation and perspectives
32328234 2020. Does the direct renin inhibitor have a role to play in attenuating severity of the outbreak coronavirus disease 2019 (COVID-19)?
32360140 ä. Bee venom and SARS-CoV-2
32345485 ä. Treatment for emerging viruses: Convalescent plasma and COVID-19
32359789 ä. COVID-19 Convalescent Plasma: Now Is the Time for Better Science
32359788 ä. Convalescent Plasma: Therapeutic Hope or Hopeless Strategy in the SARS-CoV-2 Pandemic
32289548 2020. Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
32247925 ä. Repurposing antimalarials and other drugs for COVID-19
32145386 ä. Remdesivir as a possible therapeutic option for the COVID-19
32334088 ä. SARS-CoV-2 and COVID-19: What are our options? Where should we focus our attention on to find new drugs and strategies?
32325121 ä. Tocilizumab: A new opportunity in the possible therapeutic arsenal against COVID-19
32247927 ä. Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: An evaluation of the evidence
32249063 ä. Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses
32362491 ä. Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses: (Trends in Immunology 41, 355?359; 2020)
32294562 ä. A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease
32371057 ä. Potential applications of plant biotechnology against SARS-CoV-2
32291112 ä. Ongoing Clinical Trials for the Management of the COVID-19 Pandemic
32299202 2020. COVID-19, immune system response, hyperinflammation and repurposing antirheumatic drugs
32293834 2020. Antiviral treatment of COVID-19
32295153 2020. What Does Plant-Based Vaccine Technology Offer to the Fight against COVID-19?
32235387 2020. Progress and Prospects on Vaccine Development against SARS-CoV-2
32034638 ä. Compensation of ACE2 Function for Possible Clinical Management of 2019-nCoV-Induced Acute Lung Injury
32297156 ä. Computational Identification of Small Interfering RNA Targets in SARS-CoV-2
32360300 ä. Natural product-derived phytochemicals as potential agents against coronaviruses: a review
32363219 ä. Binding site analysis of potential protease inhibitors of COVID-19 using AutoDock
32106567 2020. Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies
32098094 2020. Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376
32272550 2020. Antiviral Agents: Discovery to Resistance
32268515 2020. In Silico Discovery of Candidate Drugs against Covid-19
32357553 2020. Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19
32340120 2020. Shedding Light on the Effect of Natural Anti-Herpesvirus Alkaloids on SARS-CoV-2: A Treatment Option for COVID-19
32295237 2020. Molecular Investigation of SARS-CoV-2 Proteins and Their Interactions with Antiviral Drugs
32313883 2020. Inhaled biguanides and mTOR inhibition for influenza and coronavirus (Review)
C7118592 ä. Understanding of guidance for acupuncture and moxibustion interventions on COVID-19 (Second edition) issued by CAAM

32377965 ä. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality
32297520 2020. Can spironolactone be used to prevent COVID-19-induced acute respiratory distress syndrome in patients with hypertension?
32297519 2020. COVID-19 and vitamin D?Is there a link and an opportunity for intervention?
32191676 2020. Natural small molecules as inhibitors of coronavirus lipid-dependent attachment to host cells: a possible strategy for reducing SARS-COV-2 infectivity?
32286694 2020. Letter: Covid-19, and vitamin D Authors reply
32281109 2020. Letter: Covid-19, and vitamin D
32339299 2020. Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic?
32330314 2020. Is BCG vaccination affecting the spread and severity of COVID-19?
32349517 2020. Becoming a Faithful Defender: Traditional Chinese Medicine against Coronavirus Disease 2019 (COVID-19)
32164424 2020. COVID-19: An Update on the Epidemiological, Clinical, Preventive and Therapeutic Evidence and Guidelines of Integrative Chinese-Western Medicine for the Management of 2019 Novel Coronavirus Disease
32358817 2020. Dramatic improvement after tocilizumab of severe COVID-19 in a child with sickle cell disease and acute chest syndrome
32282956 2020. Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab
32247518 2020. COVID-19 and Chloroquine/Hydroxychloroquine: is there Ophthalmological Concern?
32207983 2020. Covid-19 infection and mortality: a physiologist?s perspective enlightening clinical features and plausible interventional strategies
32314704 2020. Ivermectin and Novel Coronavirus Disease (COVID-19): Keeping Rigor in Times of Urgency
32359210 2020. Clinical Course of COVID-19 in a Liver Transplant Recipient on Hemodialysis and Response to Tocilizumab Therapy: A Case Report
32324331 2020. COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine
32274985 2020. Novel Coronavirus Disease (COVID-19): The Need for Immunoprevention at Industrial Scale
32352178 2020. Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North-supports vitamin D as a factor determining severity Authors reply
32311755 2020. Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity

32329159 2020. Thoughts on What Chemists Can Contribute to Fighting SARS-CoV-2 - A Short Note on Hand Sanitizers, Drug Candidates and Outreach
32376597 2020. Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series
32345616 2020. Anti-inflammatory therapy may ameliorate the clinical picture of COVID-19
32304395 2020. COVID-19 Respiratory Failure: Targeting Inflammation on VV-ECMO Support

32380318 ä. Why judiciously timed anti-IL 6 therapy may be of benefit in severe COVID-19 infection
32380316 ä. Convalescent plasma in Covid-19: Possible mechanisms of action
32380315 ä. Continuous hydroxychloroquine or colchicine therapy does not prevent infection with SARS-CoV-2: Insights from a large healthcare database analysis
32376396 ä. Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia?
32376395 ä. SARS-CoV-2 infection among patients with systemic autoimmune diseases

32376403 ä. Imatinib might constitute a treatment option for lung involvement in COVID-19

32376398 ä. Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Brescia, Italy
32361195 ä. SARS-CoV-2 infection complicated by inflammatory syndrome Could high-dose human immunoglobulin for intravenous use (IVIG) be beneficial?
32304139 ä. Progress and Concept for COVID?19 Vaccine Development
32213152 2020. Are there any Therapeutic Options Currently Available for Wuhan Coronavirus?
32299796 2020. Antirheumatic agents in covid-19: is IL-6 the right target?

32366720 2020. Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
32312781 2020. Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19
32205349 2020. Updated Approaches against SARS-CoV-2
32229155 2020. Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?
32339387 2020. COVID-19, pulmonary mast cells, cytokine storms, and beneficial actions of luteolin
32282033 2020. Initiating adjunct low-dose hydroxyurea therapy for stroke prevention in children with SCA during the COVID-19 pandemic
32362106 2020. Management of conjunctivitis during the COVID-19 pandemic 2020
32302379 2020. The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19-infected patients
32366511 2020. Developing a vaccine for covid-19
32357949 2020. Covid-19: Remdesivir is helpful but not a wonder drug, say researchers
32217607 2020. Covid-19: what treatments are being investigated?
32217555 2020. Covid-19: FDA approves use of convalescent plasma to treat critically ill patients
32209549 2020. Covid-19: trials of four potential treatments to generate "robust data" of what works
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