Pneumococcal synergism

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Immunology

Pneumococcal colonization means synergism with sars cov2 ad disease expression. 13-valent pneumococcal vaccination reduces death/severity/incidence by some 30 percent, upto 90 days preexposure to antibiotics similar. 13-valent vaccination reduces surface colonization by pneumococci, 23 valent does not.

relevant pubmed items now included; pmcentral w. low specificity at 2953 total remaining to be included

this bibliography has been forwarded to P.M. Mori, Bundeskanzlerin Merkel, Gesundheitsminister Spahn, Prof. Montgomery on April 26th 2021.

index paper is

33693636 2021. Prevention of COVID-19 among older adults receiving pneumococcal conjugate vaccine suggests interactions between Streptococcus pneumoniae and SARS-CoV-2 in the respiratory tract

until further humanized work by me,


living current stringent pubmed readout on covid19 & pneumococci

Inhaltsverzeichnis

Antibiotics or Pneumococcal Vaccination and Co-Infections


33140176 ä. Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship
33010444 2021. Recommendations for antibacterial therapy in adults with COVID-19 ? an evidence based guideline
32194236 2020. Could enhanced influenza and pneumococcal vaccination programs help limit the potential damage from SARS-CoV-2 to fragile health systems of southern hemisphere countries this winter?
32482366 2020. Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS-CoV-2 agents?
33419872 2021. Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV
32600911 2020. Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality
33637783 2021. Exploratory analysis of immunization records highlights decreased SARS-CoV-2 rates in individuals with recent non-COVID-19 vaccinations
33588980 2021. Exploration of Association between Respiratory Vaccinations with Infection and Mortality Rates of COVID-19
33724440 2021. Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease
32869330 2020. Age and Location in Severity of COVID-19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?
32940090 2020. (any target vacc or cov2 vavv) Potential effects of vaccinations on the prevention of COVID-19: rationale, clinical evidence, risks, and public health considerations
32842505 2020. The Association between Influenza and Pneumococcal Vaccinations and SARS-Cov-2 Infection: Data from the EPICOVID19 Web-Based Survey
32987794 2020. Possible Cross-Reactivity between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and Death

On Pneumococcal Co-Infections


33449815 2021. Pneumococcal carriage in children with COVID-19
33883479 2021. Upper Respiratory Tract Co-detection of Human Endemic Coronaviruses and High-density Pneumococcus Associated With Increased Severity Among HIV-Uninfected Children Under 5 Years Old in the PERCH Study
33138045 2020. Effectiveness of Streptococcus Pneumoniae Urinary Antigen Testing in Decreasing Mortality of COVID-19 Co-Infected Patients: A Clinical Investigation
33828999 2021. Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections With Streptococcus pneumoniae
33462723 ä. Streptococcus pneumoniae coinfection in hospitalised patients with COVID-19
33194501 ä. Unfortunate Outcomes in Patients With SARS-CoV-2 Superimposed on Pneumococcal Pneumonia
33196783 ä. Impact of the COVID-19 Pandemic on Invasive Pneumococcal Disease and Risk of Pneumococcal Coinfection with SARS-CoV-2: prospective national cohort study, England
33274382 ä. Is there an association between SARS-CoV-2 and Streptococcus pneumoniae?
33110587 ä. SARS-CoV-2-related pneumonia cases in pneumonia picture in Russia in March-May 2020: Secondary bacterial pneumonia and viral co-infections
33188161 2020. A Retrospective Study of Coinfection of SARS-CoV-2 and Streptococcus pneumoniae in 11 Hospitalized Patients with Severe COVID-19 Pneumonia at a Single Center

Casual Pneumococcal Co-Infections


33443011 2021. Lung Pathology of Mutually Exclusive Co-infection with SARS-CoV-2 and Streptococcus pneumoniae
33738165 ä. A Double Whammy: A Case Report and Review of the Literature on Pneumococcal Coinfection in COVID-19 Patients
33791177 ä. Invasive Pneumococcal Disease in a Patient With COVID-19: A Case Report
33343959 2020. Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases
32430579 ä. 18F -FDG PET/CT for suspected lymphoma relapse in a patient with concomitant pneumococcal pneumonia during COVID-19 outbreak: unexpected SARS-Cov-2 co-infection despite double RT-PCR negativity
33865698 ä. Invasive pneumococcal disease affected the fatal outcome in a COVID-19 patient
32639585 ä. Pneumococcal co?infection in Covid?19 patients
33521301 2020. Pneumococcal superinfection in COVID-19 patients: A series of 5 cases
33469593 ä. Bacterial superinfection pneumonia in SARS-CoV-2 respiratory failure
32602267 ä. SARS?CoV?2 and Streptococcus pneumoniae coinfection as a cause of severe pneumonia in an infant



Any bacteria Co-Infections


33818909 2021. Clinical and etiological analysis of co-infections and secondary infections in COVID-19 patients: An observational study
33391970 2020. Bacterial co-infections and antibiotic resistance in patients with COVID-19
32959802 2020. Bacterial coinfections in COVID-19: an underestimated adversary
32770825 ä. Bacterial co?infections with SARS?CoV?2
32535894 ä. Bloodstream infections in critically ill patients with COVID?19
33413990 ä. Infecci�n bacteriana/f�ngica en pacientes con COVID-19 ingresados en un hospital de tercer nivel de Castilla y Le�n, Espa�a
32603803 2020. Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting
32745596 2021. Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study
33014484 2020. SARS-CoV2 and Co-Infections: A Review of Two Cases
33618663 2021. Community-acquired bacteraemia in COVID-19 in comparison to influenza A and influenza B: a retrospective cohort study
32894364 2020. Bacterial and viral co-infections in patients with severe SARS-CoV-2 pneumonia admitted to a French ICU
32314699 ä. Case Report: The Importance of Novel Coronavirus Disease (COVID-19) and Coinfection with Other Respiratory Pathogens in the Current Pandemic
33477076 2021. Unusual cause of acute sinusitis and orbital abscess in COVID-19 positive patient: Case report
33393790 ä. Metaproteomics Analysis of SARS-CoV-2-Infected Patient Samples Reveals Presence of Potential Coinfecting Microorganisms
33530280 2021. Co-infection in patients with hypoxemic pneumonia due to COVID-19 in Reunion Island
33725930 2021. Co-infections of SARS-CoV-2 with multiple common respiratory pathogens in infected children: A retrospective study
33749214 2021. Aspectos microbiol�gicos actuales de la infecci�n respiratoria comunitaria m�s all� de la COVID-19
33861190 2021. Co-infection in critically ill patients with COVID-19: an observational cohort study from England
33103530 2021. Few bacterial co-infections but frequent empiric antibiotic use in the early phase of hospitalized patients with COVID-19: results from a multicentre retrospective cohort study in The Netherlands


Microbiome deviation


32255312 2020. A possible probiotic (S salivarius K12) approach to improve oral and lung microbiotas and raise defenses against SAR S-CoV-2
32497191 ä. Alterations of the Gut Microbiota in Patients with COVID-19 or H1N1 Influenza
33685349 ä. SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota
32690600 2021. Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19

SEA paradoxon: less pneumococcal infections


32956735 2021. Decline in invasive pneumococcal disease during COVID-19 pandemic in Taiwan
32810519 2020. Decline in pneumococcal disease incidence in the time of COVID-19 in Singapore
33020740 2020. Collateral benefits on other respiratory infections during fighting COVID-19
32458547 ä. Decline in invasive pneumococcus diseases while combating the COVID?19 pandemic in Taiwan

Funghi


33277340 2021. Frequency of Positive Aspergillus Tests in COVID-19 Patients in Comparison to Other Patients with Pulmonary Infections Admitted to the Intensive Care Unit


Something


32987794 2020. Possible Cross-Reactivity between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and Death
32817331 2020. Single Amino Acid Replacements in RocA Disrupt Protein-Protein Interactions To Alter the Molecular Pathogenesis of Group A Streptococcus
33170499 ä. Etiology of Severe Community-Acquired Pneumonia in Adults Based on Metagenomic Next-Generation Sequencing: A Prospective Multicenter Study
32434842 2020. RocA Regulates Phosphatase Activity of Virulence Sensor CovS of Group A Streptococcus in Growth Phase- and pH-Dependent Manners
32657436 ä. Can medicinal mushrooms have prophylactic or therapeutic effect against COVID?19 and its pneumonic superinfection and complicating inflammation?
32805298 2021. Updates on community acquired pneumonia management in the ICU
33470665 2021. Pneumonia in older adults
33619170 2021. Vaccines for older adults
33884095 2021. The Virtual Streptococcal Seminar Series and Trainee Symposium: Adaptations of a Research Community during the COVID-19 Pandemic
33022727 2020. Neues zu Impfungen bei Erwachsenen
33513649 2021. Steroide in der Infektionsmedizin
33031142 2020. Impact of COVID-19 Quarantine and School Cancelation on Other Common Infectious Diseases
33469204 2021. Rogue antibodies could be driving severe COVID-19
33512346 2021. Antibacterial drugs for community-acquired pneumonia

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