PHA SCR nsp15 endoribonuclease

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PHA pharmacophore by screened target
living current stringent pubmed readout on nsp15 endoribonuclease

32304108 2020. Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2

32885740 2020. Identification of promising antiviral drug candidates against non-structural protein 15 (NSP15) from SARS-CoV-2: an in silico assisted drug-repurposing study.
32943302 2020. Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus replication.
33155531 2020. Identification and characterization of novel RdRp and Nsp15 inhibitors for SARS-COV2 using computational approach.
33271751 2020. Identification of Persuasive Antiviral Natural Compounds for COVID-19 by Targeting Endoribonuclease NSP15: A Structural-Bioinformatics Approach.
33275961 2020. Drug designing against NSP15 of SARS-COV2 via high throughput computational screening and structural dynamics approach.
C7351674 2020. Structure-based drug designing towards the identification of potential anti-viral for COVID-19 by targeting endoribonuclease NSP15.

32188729 2020. Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages.

32835632 2020. In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2.

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