PHA SCR nsp10 nsp16 methyltransferase

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PHA pharmacophore by screened target
living current stringent pubmed readout on nsp10,16 methyltransferase

"nonstructural protein 16 (nsp16) of coronavirus is an S-adenosyl methionine (SAM)-dependent 2'-O-methyltransferase (2'-O-MTase) that has an important role in viral replication and prevents recognition by the host innate immune system" 32835632

32741322 2020. Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study.
32835632 2020. In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2.
33252031 2020. Identification of naphthyridine and quinoline derivatives as potential Nsp16-Nsp10 inhibitors: a pharmacoinformatics study.
32738360 2020. Computational guided drug repurposing for targeting 2'-O-ribose methyltransferase of SARS-CoV-2.
33016237 2020. Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus.

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