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  papers considered essetial reading from trmp7 2019-2021
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related topics
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*[[PHA Sacubitril]]
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*[https://archive.org/details/trmp-7-derangement Is Covid19 a TRPM7 derangement syndrome]
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*[https://archive.org/details/implementiert-magnesium Implementiert Magnesium - Aufruf an die Regierenden]
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*[[Magnesium Amiloride]] amiloride elevates intracellular magnesium should inhibit trpm7
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*[[Magnesium SLC41A1]] the amiloride sensitive Mg efflux channel
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*[[Magnesium beta blocker]] beta blockers increase intracellular magnesium ?
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*[[Magnesium-loosing diuretics: Thiazides]]
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*[[Magnasium-sparing diuretics: Aldosterone antagonists]]
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*[[Magnesium Cobalt als Mediator]]
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*[[Magnesium CNNM accessory proteins]]
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*[[Aldosterone Cobalt]]
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*[[Aldosterone Covid19]]
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*[[Cobalt Covid19]]
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  papers considered essential reading from trmp7 2019-2021
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{{ttp|p=34360104|t=2021. Effect of Environmental Pollutants PM2.5, CO, NO2, and O3 on the Incidence and Mortality of SARS-CoV-2 Infection in Five Regions of the USA.|pdf=|usr=}} pm2.5 is something and cobalt and nickel
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{{ttp|p=30596515|t=2019. Tubular flow activates magnesium transport in the distal convoluted tubule.|pdf=|usr=}}
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{{xtp|p=34524085|t=2021. The magnesium global network (MaGNet) to promote research on magnesium in diseases focusing on covid-19.|pdf=https://www.jle.com/fr/revues/mrh/e-docs/the_magnesium_global_network_magnet_to_promote_research_on_magnesium_in_diseases_focusing_on_covid_19_320063/article.phtml?tab=texte|usr=}}
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*'''[https://www.sdrmsociety.org/ Magnesium Club]'''
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{{ttp|p=34580159|t=2021. Serum magnesium levels in hospitalized patients with SARS-CoV-2 |pdf=|usr=}}
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Higher Mg(o) means lower Mg(i) by redistribution means higher TRPM7 and data gets interpretable, the culprit should lie at mg extrusion channels or at modified mg leitfähigkeit siemens of trpm7 so trmp7 to target directly e.a. scabutril or something around amilorid for the secretion i have to check this literture
  
 
{{tp|p=31993307|t=2020. Solute carrier transporters: the metabolic gatekeepers of immune cells.|pdf=|usr=}}
 
{{tp|p=31993307|t=2020. Solute carrier transporters: the metabolic gatekeepers of immune cells.|pdf=|usr=}}
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{{tp|p=32430797|t=2021. TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury.|pdf=|usr=}}
 
{{tp|p=32430797|t=2021. TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury.|pdf=|usr=}}
 
{{tp|p=30678852|t=2019. Aldosterone and Ion Channels.|pdf=|usr=}}
 
{{tp|p=30678852|t=2019. Aldosterone and Ion Channels.|pdf=|usr=}}
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additional batch from pmc 2019-2022
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{{tp|p=32603001|t=2021. Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney.|pdf=|usr=}}
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{{tp|p=29047094|t=2017. Endothelial Cell Reactive Oxygen Species and Ca(2+) Signaling in Pulmonary Hypertension.|pdf=|usr=}}
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{{tp|p=32328412|t=2020. Biodegradable Magnesium-Based Implants in Orthopedics-A General Review and Perspectives.|pdf=|usr=}}
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{{tp|p=31076559|t=2019. Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.|pdf=|usr=}}
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{{tp|p=30541094|t=2018. Personalized magnesium intervention to improve vitamin D metabolism: applying a systems approach for precision nutrition in large randomized trials of diverse populations.|pdf=|usr=}}
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{{tp|p=30541089|t=2018. Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial.|pdf=|usr=}}
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{{tp|p=29351417|t=2018. Zinc regulates vascular endothelial cell activity through zinc-sensing receptor ZnR/GPR39.|pdf=|usr=}}
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{{tp|p=34532429|t=2021. The effects of a biodegradable Mg-based alloy on the function of VSMCs via immunoregulation of macrophages through Mg-induced responses.|pdf=|usr=}}
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{{tp|p=31807559|t=2019. Magnesium and liver disease.|pdf=|usr=}}
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{{tp|p=32663035|t=2020. Cellular Mechanisms of NETosis.|pdf=|usr=}}
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{{tp|p=32977544|t=2020. Magnesium, Oxidative Stress, Inflammation, and Cardiovascular Disease.|pdf=|usr=}}
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{{tp|p=29367228|t=2018. TRPing out Platelet Calcium: TRPM7 (Transient Receptor Potential Melastatin-Like 7) Modulates Calcium Mobilization and Platelet Function via Phospholipase C Interactions.|pdf=|usr=}}
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{{tp|p=29563117|t=2018. Platelet Signaling Pathways and New Inhibitors.|pdf=|usr=}}
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{{tp|p=34541389|t=2022. Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/beta-catenin signaling.|pdf=|usr=}}
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{{tp|p=25184538|t=2014. Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.|pdf=|usr=}}
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{{tp|p=32685466|t=2020. Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-kappaB Signaling Pathway.|pdf=|usr=}}
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{{tp|p=32337263|t=2020. Effect of Carvacrol, TRP Channels Modulator, on Cardiac Electrical Activity.|pdf=|usr=}}
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{{tp|p=33513920|t=2021. Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities.|pdf=|usr=}}
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{{tp|p=34213669|t=2021. 'Magnesium'-the master cation-as a drug-possibilities and evidences.|pdf=|usr=}}
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{{tp|p=29478069|t=2018. Magnesium in Chronic Kidney Disease: Should We Care?|pdf=|usr=}}
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{{tp|p=32393384|t=2020. Effect of long-term treatment of Carvacrol on glucose metabolism in Streptozotocin-induced diabetic mice.|pdf=|usr=}}
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{{tp|p=32913008|t=2020. Vimentin as a target for the treatment of COVID-19.|pdf=|usr=}}
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{{tp|p=31192005|t=2019. Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency.|pdf=|usr=}}
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{{tp|p=33035451|t=2020. Lactate Elicits ER-Mitochondrial Mg(2+) Dynamics to Integrate Cellular Metabolism.|pdf=|usr=}}
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{{tp|p=31812825|t=2020. A structural overview of the ion channels of the TRPM family.|pdf=|usr=}}
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{{tp|p=32140260|t=2020. 2-Aminoethoxydiphenylborate (2-APB) inhibits release of phosphatidylserine-exposing extracellular vesicles from platelets.|pdf=|usr=}}
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{{tp|p=34089346|t=2021. ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs.|pdf=|usr=}}
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{{tp|p=29500477|t=2018. The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins.|pdf=|usr=}}
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{{tp|p=33238121|t=2020. Mitochondrial Ca(2+) Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing.|pdf=|usr=}}
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{{tp|p=34359914|t=2021. High Intakes of Bioavailable Phosphate May Promote Systemic Oxidative Stress and Vascular Calcification by Boosting Mitochondrial Membrane Potential-Is Good Magnesium Status an Antidote?|pdf=|usr=}}
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{{tp|p=33291725|t=2020. TRPM Channels in Human Diseases.|pdf=|usr=}}
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{{tp|p=30486272|t=2018. Carvacrol Attenuates Hippocampal Neuronal Death after Global Cerebral Ischemia via Inhibition of Transient Receptor Potential Melastatin 7.|pdf=|usr=}}
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{{tp|p=31184289|t=2019. TRP ion channels: Proteins with conformational flexibility.|pdf=|usr=}}
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{{tp|p=34166652|t=2021. TRP channels in COVID-19 disease: Potential targets for prevention and treatment.|pdf=|usr=}}
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{{tp|p=33405100|t=2021. New Insights on the Role of TRP Channels in Calcium Signalling and Immunomodulation: Review of Pathways and Implications for Clinical Practice.|pdf=|usr=}}
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{{tp|p=32706027|t=2020. Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function.|pdf=|usr=}}
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{{tp|p=25169754|t=2015. Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicity.|pdf=|usr=}}
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{{tp|p=34017036|t=2021. TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel.|pdf=|usr=}}
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{{tp|p=31187891|t=2019. Transient Receptor Potential Channels and Endothelial Cell Calcium Signaling.|pdf=|usr=}}
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{{tp|p=32863400|t=2020. Nigella sativa L as a potential phytotherapy for coronavirus disease 2019: A mini review of in silico studies.|pdf=|usr=}}
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{{tp|p=32982178|t=2020. Astragaloside IV: An Effective Drug for the Treatment of Cardiovascular Diseases.|pdf=|usr=}}
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{{tp|p=34729244|t=2021. Potential treatment of COVID-19 with traditional chinese medicine: What herbs can help win the battle with SARS-CoV-2?|pdf=|usr=}}
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{{tp|p=34687321|t=2021. The relevance of magnesium homeostasis in COVID-19.|pdf=|usr=}}
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{{tp|p=33163084|t=2020. Carvacrol: An In Silico Approach of a Candidate Drug on HER2, PI3Kalpha, mTOR, hER-alpha, PR, and EGFR Receptors in the Breast Cancer.|pdf=|usr=}}
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{{tp|p=33456540|t=2021. Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review).|pdf=|usr=}}
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{{tp|p=33747462|t=2021. Association of dietary calcium, magnesium, and vitamin D with type 2 diabetes among US adults: National health and nutrition examination survey 2007-2014-A cross-sectional study.|pdf=|usr=}}
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{{tp|p=33282857|t=2020. The Role of Disturbed Mg Homeostasis in Chronic Kidney Disease Comorbidities.|pdf=|usr=}}
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{{tp|p=34504502|t=2021. The Molecular Mechanism of Multiple Organ Dysfunction and Targeted Intervention of COVID-19 Based on Time-Order Transcriptomic Analysis.|pdf=|usr=}}
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{{tp|p=31849975|t=2019. A Biodegradable Mg-Based Alloy Inhibited the Inflammatory Response of THP-1 Cell-Derived Macrophages Through the TRPM7-PI3K-AKT1 Signaling Axis.|pdf=|usr=}}
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{{tp|p=34489714|t=2021. An Insight on Multicentric Signaling of Angiotensin II in Cardiovascular system: A Recent Update.|pdf=|usr=}}
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{{tp|p=33959029|t=2021. The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19.|pdf=|usr=}}
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{{tp|p=31572181|t=2019. Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice.|pdf=|usr=}}
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{{tp|p=33296687|t=2020. Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.|pdf=|usr=}}
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{{tp|p=29343440|t=2018. Chanzyme TRPM7 Mediates the Ca(2+) Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.|pdf=|usr=}}
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{{tp|p=31955624|t=2020. Molecular regulation of TLR signaling in health and disease: mechano-regulation of macrophages and TLR signaling.|pdf=|usr=}}
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{{tp|p=33447739|t=2019. Association of hypomagnesemia with cardiovascular diseases and hypertension.|pdf=|usr=}}
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{{tp|p=33803491|t=2021. TRP Channels as Cellular Targets of Particulate Matter.|pdf=|usr=}}
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{{tp|p=32992944|t=2020. A Review of the Action of Magnesium on Several Processes Involved in the Modulation of Hematopoiesis.|pdf=|usr=}}
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{{tp|p=32698380|t=2020. Carotid Body and Metabolic Syndrome: Mechanisms and Potential Therapeutic Targets.|pdf=|usr=}}
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{{tp|p=31991573|t=2020. The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis.|pdf=|usr=}}
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{{tp|p=32756352|t=2020. Exploring the Mediators that Promote Carotid Body Dysfunction in Type 2 Diabetes and Obesity Related Syndromes.|pdf=|usr=}}
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{{tp|p=30845649|t=2019. Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators.|pdf=|usr=}}
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{{tp|p=30889804|t=2019. Effects of Magnesium Deficiency on Mechanisms of Insulin Resistance in Type 2 Diabetes: Focusing on the Processes of Insulin Secretion and Signaling.|pdf=|usr=}}
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{{tp|p=31284572|t=2019. The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.|pdf=|usr=}}
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{{tp|p=31336935|t=2019. Magnesium Is a Key Player in Neuronal Maturation and Neuropathology.|pdf=|usr=}}
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{{tp|p=30995736|t=2019. TRPM7, Magnesium, and Signaling.|pdf=|usr=}}
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{{tp|p=34703991|t=2021. MR-PheWAS for the causal effects of serum magnesium on multiple disease outcomes in Caucasian descent.|pdf=|usr=}}
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{{tp|p=31036759|t=2019. A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD.|pdf=|usr=}}
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{{tp|p=29093028|t=2018. Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes.|pdf=|usr=}}
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{{tp|p=33971585|t=2021. An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19.|pdf=|usr=}}
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{{tp|p=34499925|t=2021. The Mitochondrial Ca(2+) uniporter is a central regulator of interorganellar Ca(2+) transfer and NFAT activation.|pdf=|usr=}}
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{{tp|p=31974165|t=2020. Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation.|pdf=|usr=}}
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{{tp|p=32439805|t=2020. The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion.|pdf=|usr=}}
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{{tp|p=30076216|t=2018. TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis.|pdf=|usr=}}
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{{tp|p=29866880|t=2018. The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells.|pdf=|usr=}}
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{{tp|p=32147957|t=2020. MiR-9 promotes angiogenesis of endothelial progenitor cell to facilitate thrombi recanalization via targeting TRPM7 through PI3K/Akt/autophagy pathway.|pdf=|usr=}}
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{{tp|p=33314296|t=2021. Association of circulating long non-coding RNA HULC expression with disease risk, inflammatory cytokines, biochemical index levels, severity-assessed scores, and mortality of sepsis.|pdf=|usr=}}
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{{tp|p=30819230|t=2019. TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling.|pdf=|usr=}}
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{{tp|p=33571553|t=2021. Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH.|pdf=|usr=}}
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{{tp|p=34045880|t=2021. The ACE2-Ang-(17)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Mediated NF-small ka, Cyrillicb and MAPK Pathways.|pdf=|usr=}}
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{{tp|p=30826804|t=2019. Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience.|pdf=|usr=}}
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{{tp|p=31392789|t=2019. Frontline Science: Escherichia coli use LPS as decoy to impair neutrophil chemotaxis and defeat antimicrobial host defense.|pdf=|usr=}}
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{{tp|p=30861205|t=2019. Biophysical regulation of macrophages in health and disease.|pdf=|usr=}}
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{{tp|p=33481059|t=2021. Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches.|pdf=|usr=}}
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{{tp|p=29383719|t=2018. CrossTalk proposal: CNNM proteins are Na(+) /Mg(2+) exchangers playing a central role in transepithelial Mg(2+) (re)absorption.|pdf=|usr=}}
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{{tp|p=31194171|t=2019. Diabetes Mellitus Modifies the Associations of Serum Magnesium Concentration With Arterial Calcification and Stiffness in Incident Hemodialysis Patients.|pdf=|usr=}}
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{{tp|p=30987399|t=2019. Magnesium: The Forgotten Electrolyte-A Review on Hypomagnesemia.|pdf=|usr=}}
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{{tp|p=31392516|t=2020. Magnesium-Induced Cell Survival Is Dependent on TRPM7 Expression and Function.|pdf=|usr=}}
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{{tp|p=29910176|t=2018. EMAPII Monoclonal Antibody Ameliorates Influenza A Virus-Induced Lung Injury.|pdf=|usr=}}
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{{tp|p=34059671|t=2021. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.|pdf=|usr=}}
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{{tp|p=34001887|t=2021. TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration.|pdf=|usr=}}
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{{tp|p=34112781|t=2021. TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection.|pdf=|usr=}}
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{{tp|p=32415068|t=2020. The native ORAI channel trio underlies the diversity of Ca(2+) signaling events.|pdf=|usr=}}
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{{tp|p=30622345|t=2019. Calcium signalling in T cells.|pdf=|usr=}}
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{{tp|p=31605492|t=2020. Calciprotein particle inhibition explains magnesium-mediated protection against vascular calcification.|pdf=|usr=}}
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{{tp|p=33808247|t=2021. Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.|pdf=|usr=}}
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{{tp|p=34444647|t=2021. Editorial of Special Issue "Magnesium in Human Health and Disease".|pdf=|usr=}}
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{{tp|p=33435521|t=2021. Magnesium in Infectious Diseases in Older People.|pdf=|usr=}}
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{{tp|p=33573164|t=2021. Magnesium in Aging, Health and Diseases.|pdf=|usr=}}
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{{tp|p=33499378|t=2021. Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes.|pdf=|usr=}}
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{{tp|p=30813254|t=2019. Magnesium: A Magic Bullet for Cardiovascular Disease in Chronic Kidney Disease?|pdf=|usr=}}
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{{tp|p=32215176|t=2020. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1alpha.|pdf=|usr=}}
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{{tp|p=32964285|t=2020. TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity.|pdf=|usr=}}
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{{tp|p=30417250|t=2019. SLC41A1 is essential for magnesium homeostasis in vivo.|pdf=|usr=}}
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{{tp|p=34278747|t=2021. An overview of diagnosis and management of drug-induced hypomagnesemia.|pdf=|usr=}}
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{{tp|p=32706793|t=2020. Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice.|pdf=|usr=}}
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{{tp|p=32074140|t=2020. Microvasculopathy and soft tissue calcification in mice are governed by fetuin-A, magnesium and pyrophosphate.|pdf=|usr=}}
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{{tp|p=30615643|t=2019. TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.|pdf=|usr=}}
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{{tp|p=30770447|t=2019. TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival.|pdf=|usr=}}
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{{tp|p=30718434|t=2019. Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism.|pdf=|usr=}}
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{{tp|p=33859252|t=2021. Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.|pdf=|usr=}}
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{{tp|p=32047249|t=2020. TRPM7 contributes to progressive nephropathy.|pdf=|usr=}}
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{{tp|p=33544938|t=2021. Metabolic sensor O-GlcNAcylation regulates megakaryopoiesis and thrombopoiesis through c-Myc stabilization and integrin perturbation.|pdf=|usr=}}
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{{tp|p=32711944|t=2020. CRAC Channels and Calcium Signaling in T Cell-Mediated Immunity.|pdf=|usr=}}
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{{tp|p=32494148|t=2020. Vascular Calcification: An Important Understanding in Nephrology.|pdf=|usr=}}

Aktuelle Version vom 23. Dezember 2021, 09:46 Uhr

related topics
papers considered essential reading from trmp7 2019-2021
34360104 2021. Effect of Environmental Pollutants PM2.5, CO, NO2, and O3 on the Incidence and Mortality of SARS-CoV-2 Infection in Five Regions of the USA.
pm2.5 is something and cobalt and nickel
30596515 2019. Tubular flow activates magnesium transport in the distal convoluted tubule.
34524085 2021. The magnesium global network (MaGNet) to promote research on magnesium in diseases focusing on covid-19. PDF direct


34580159 2021. Serum magnesium levels in hospitalized patients with SARS-CoV-2

Higher Mg(o) means lower Mg(i) by redistribution means higher TRPM7 and data gets interpretable, the culprit should lie at mg extrusion channels or at modified mg leitfähigkeit siemens of trpm7 so trmp7 to target directly e.a. scabutril or something around amilorid for the secretion i have to check this literture


31993307 2020. Solute carrier transporters: the metabolic gatekeepers of immune cells.
31559137 2019. Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1.
32484206 2020. LPS promotes the progression of sepsis by activation of lncRNA HULC/miR-204-5p/TRPM7 network in HUVECs.
30538170 2019. Procaspase activating compound 1 controls tetracycline repressor-regulated gene expression system.
32684624 2020. A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma.
31250885 2020. Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.
31812825 2020. A structural overview of the ion channels of the TRPM family.
33922466 2021. Channelling the Force to Reprogram the Matrix: Mechanosensitive Ion Channels in Cardiac Fibroblasts.
33291725 2020. TRPM Channels in Human Diseases.
32643506 2020. A bibliometric analysis and review of recent researches on TRPM7.
31697634 2019. Leptin Activates Trpm7 Channels in the Carotid Body As a Mechanism of Obesity-Related Hypertension.
31545149 2019. Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.
34017036 2021. TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel.
32315468 2020. TRPM6 and TRPM7: Novel players in cell intercalation during vertebrate embryonic development.
34569930 2021. TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis.
34766907 2021. The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.
31115020 2019. The expression of TRPM7 in serum of patients with sepsis, its influences on inflammatory factors and prognosis, and its diagnostic value.
33456540 2021. Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review).
34307382 2021. Cell Death Induction and Protection by Activation of Ubiquitously Expressed Anion/Cation Channels. Part 2: Functional and Molecular Properties of ASOR/PAC Channels and Their Roles in Cell Volume Dysregulation and Acidotoxic Cell Death.
33511120 2020. Cell Death Induction and Protection by Activation of Ubiquitously Expressed Anion/Cation Channels. Part 1: Roles of VSOR/VRAC in Cell Volume Regulation, Release of Double-Edged Signals and Apoptotic/Necrotic Cell Death.
32733880 2020. TRPM7/RPSA Complex Regulates Pancreatic Cancer Cell Migration.
33658993 2020. TRPM7 Kinase Is Essential for Neutrophil Recruitment and Function via Regulation of Akt/mTOR Signaling.
31849975 2019. A Biodegradable Mg-Based Alloy Inhibited the Inflammatory Response of THP-1 Cell-Derived Macrophages Through the TRPM7-PI3K-AKT1 Signaling Axis.
31921670 2019. TRPM7 Induces Mechanistic Target of Rap1b Through the Downregulation of miR-28-5p in Glioma Proliferation and Invasion.
33927631 2021. Blockade of TRPM7 Alleviates Chondrocyte Apoptosis and Articular Cartilage Damage in the Adjuvant Arthritis Rat Model Through Regulation of the Indian Hedgehog Signaling Pathway.
33132914 2020. TRP Channels and Small GTPases Interplay in the Main Hallmarks of Metastatic Cancer.
34733174 2021. NSAIDs Naproxen, Ibuprofen, Salicylate, and Aspirin Inhibit TRPM7 Channels by Cytosolic Acidification.
32038296 2019. Endothelial Transient Receptor Potential Channels and Vascular Remodeling: Extracellular Ca(2 +) Entry for Angiogenesis, Arteriogenesis and Vasculogenesis.
30453391 2019. Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production.
33993722 2021. Pharmacological and Genetic Blockade of Trpm7 in the Carotid Body Treats Obesity-Induced Hypertension.
34682454 2021. Potential Implications of Mammalian Transient Receptor Potential Melastatin 7 in the Pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Review.
32977698 2020. Mapping TRPM7 Function by NS8593.
33114331 2020. The Transient Receptor Potential Melastatin 7 (TRPM7) Inhibitors Suppress Seizure-Induced Neuron Death by Inhibiting Zinc Neurotoxicity.
30995736 2019. TRPM7, Magnesium, and Signaling.
33726758 2021. O-GlcNAcylation homeostasis controlled by calcium influx channels regulates multiple myeloma dissemination.
30819230 2019. TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling.
32162606 2019. Reactive oxygen species are implicated in altering magnesium homeostasis in endothelial cells exposed to high glucose.
31392516 2020. Magnesium-Induced Cell Survival Is Dependent on TRPM7 Expression and Function.
32215176 2020. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1alpha.
32964285 2020. TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity.
31293101 2019. TRPM7 is involved in acid-induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells.
30615643 2019. TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.
33893091 2021. Hydraulic resistance induces cell phenotypic transition in confinement.
32047249 2020. TRPM7 contributes to progressive nephropathy.
34158860 2021. Inhibition of SENP6 restrains cerebral ischemia-reperfusion injury by regulating Annexin-A1 nuclear translocation-associated neuronal apoptosis.
33691194 2021. Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension.
32994545 2020. Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead.
33891828 2021. Leptin Induces Epigenetic Regulation of Transient Receptor Potential Melastatin 7 in Rat Adrenal Pheochromocytoma Cells.
31848974 2020. Carvacrol effectively protects demyelination by suppressing transient receptor potential melastatin 7 (TRPM7) in Schwann cells.
33989904 2021. CCT128930 is a novel and potent antagonist of TRPM7 channel.
34175300 2021. Cell death modulation by transient receptor potential melastatin channels TRPM2 and TRPM7 and their underlying molecular mechanisms.
33143990 2021. Panax Notoginseng Saponins suppresses TRPM7 via the PI3K/AKT pathway to inhibit hypertrophic scar formation in vitro.
31640089 2019. TRPM7 deficiency suppresses cell proliferation, migration, and invasion in human colorectal cancer via regulation of epithelial-mesenchymal transition.
34752845 2021. Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy.
31504274 2020. The TRPM7 channel kinase: rekindling an old flame or not?
33784560 2021. Role of TRPM7 kinase in cancer.
32683175 2020. Insights and perspectives on calcium channel functions in the cockpit of cancerous space invaders.
33080445 2020. Inhibition of TRPM7 with waixenicin A reduces glioblastoma cellular functions.
31176886 2019. Focus on TRP channels in cystic fibrosis.
31073743 2019. Role of the chanzyme TRPM7 in the nervous system in health and disease.
30710498 2019. miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7.
32924998 2021. Protective effect of inhibiting TRPM7 expression on hypoxia post-treatment H9C2 cardiomyocytes.
31288723 2019. Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: a New Target for Sepsis.
32503408 2020. The TRPM7 Channel in the Nervous and Cardiovascular Systems.
31060485 2019. Roles of TRPM7 in Renal Ischemia-Reperfusion Injury.
34511254 2021. A comprehensive review of hypomagnesemia.
33647257 2021. Carvacrol alleviates liver fibrosis by inhibiting TRPM7 and modulating the MAPK signaling pathway.
30596515 2019. Tubular flow activates magnesium transport in the distal convoluted tubule.
33356397 2021. Magnesium Supplementation Attenuates Pulmonary Hypertension via Regulation of Magnesium Transporters.
34558663 2021. Immunomodulatory functions of TRPM7 and its implications in autoimmune diseases.
34045316 2021. Molecular Mechanisms of Renal Magnesium Reabsorption.
30508321 2019. Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts.
33951695 2021. MiR-129-5p Protects H9c2 Cardiac Myoblasts From Hypoxia/Reoxygenation Injury by Targeting TRPM7 and Inhibiting NLRP3 Inflammasome Activation.
31180948 2019. Magnesium-responsive genes are downregulated in diabetic patients after a three-month exercise program on a bicycle ergometer.
34302186 2021. Magnesium transport in the aglomerular kidney of the Gulf toadfish (Opsanus beta).
31739105 2020. Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-beta/Smads pathway.
33494094 2021. Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.
31444399 2020. TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia.
33210606 2020. Magnesium deficiency with high calcium-to-magnesium ratio promotes a metastatic phenotype in the CT26 colon cancer cell line.
32162608 2019. Magnesium transport and homeostasis-related gene expression in skeletal muscle of young and old adults: analysis of the transcriptomic data from the PROOF cohort Study.
29672725 2019. Down-Regulated Expression of Magnesium Transporter Genes Following a High Magnesium Diet Attenuates Sciatic Nerve Crush Injury.
31844251 2020. Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.
30406297 2019. Magnesium Extravaganza: A Critical Compendium of Current Research into Cellular Mg(2+) Transporters Other than TRPM6/7.
33221129 2021. Magnesium and inflammation: Advances and perspectives.
32430797 2021. TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury.
30678852 2019. Aldosterone and Ion Channels.

additional batch from pmc 2019-2022


32603001 2021. Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney.
29047094 2017. Endothelial Cell Reactive Oxygen Species and Ca(2+) Signaling in Pulmonary Hypertension.
32328412 2020. Biodegradable Magnesium-Based Implants in Orthopedics-A General Review and Perspectives.
31076559 2019. Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.
30541094 2018. Personalized magnesium intervention to improve vitamin D metabolism: applying a systems approach for precision nutrition in large randomized trials of diverse populations.
30541089 2018. Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial.
29351417 2018. Zinc regulates vascular endothelial cell activity through zinc-sensing receptor ZnR/GPR39.
34532429 2021. The effects of a biodegradable Mg-based alloy on the function of VSMCs via immunoregulation of macrophages through Mg-induced responses.
31807559 2019. Magnesium and liver disease.
32663035 2020. Cellular Mechanisms of NETosis.
32977544 2020. Magnesium, Oxidative Stress, Inflammation, and Cardiovascular Disease.
29367228 2018. TRPing out Platelet Calcium: TRPM7 (Transient Receptor Potential Melastatin-Like 7) Modulates Calcium Mobilization and Platelet Function via Phospholipase C Interactions.
29563117 2018. Platelet Signaling Pathways and New Inhibitors.
34541389 2022. Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/beta-catenin signaling.
25184538 2014. Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
32685466 2020. Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-kappaB Signaling Pathway.
32337263 2020. Effect of Carvacrol, TRP Channels Modulator, on Cardiac Electrical Activity.
33513920 2021. Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities.
34213669 2021. 'Magnesium'-the master cation-as a drug-possibilities and evidences.
29478069 2018. Magnesium in Chronic Kidney Disease: Should We Care?
32393384 2020. Effect of long-term treatment of Carvacrol on glucose metabolism in Streptozotocin-induced diabetic mice.
32913008 2020. Vimentin as a target for the treatment of COVID-19.
31192005 2019. Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency.
33035451 2020. Lactate Elicits ER-Mitochondrial Mg(2+) Dynamics to Integrate Cellular Metabolism.
31812825 2020. A structural overview of the ion channels of the TRPM family.
32140260 2020. 2-Aminoethoxydiphenylborate (2-APB) inhibits release of phosphatidylserine-exposing extracellular vesicles from platelets.
34089346 2021. ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs.
29500477 2018. The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins.
33238121 2020. Mitochondrial Ca(2+) Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing.
34359914 2021. High Intakes of Bioavailable Phosphate May Promote Systemic Oxidative Stress and Vascular Calcification by Boosting Mitochondrial Membrane Potential-Is Good Magnesium Status an Antidote?
33291725 2020. TRPM Channels in Human Diseases.
30486272 2018. Carvacrol Attenuates Hippocampal Neuronal Death after Global Cerebral Ischemia via Inhibition of Transient Receptor Potential Melastatin 7.
31184289 2019. TRP ion channels: Proteins with conformational flexibility.
34166652 2021. TRP channels in COVID-19 disease: Potential targets for prevention and treatment.
33405100 2021. New Insights on the Role of TRP Channels in Calcium Signalling and Immunomodulation: Review of Pathways and Implications for Clinical Practice.
32706027 2020. Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function.
25169754 2015. Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicity.
34017036 2021. TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel.
31187891 2019. Transient Receptor Potential Channels and Endothelial Cell Calcium Signaling.
32863400 2020. Nigella sativa L as a potential phytotherapy for coronavirus disease 2019: A mini review of in silico studies.
32982178 2020. Astragaloside IV: An Effective Drug for the Treatment of Cardiovascular Diseases.
34729244 2021. Potential treatment of COVID-19 with traditional chinese medicine: What herbs can help win the battle with SARS-CoV-2?
34687321 2021. The relevance of magnesium homeostasis in COVID-19.
33163084 2020. Carvacrol: An In Silico Approach of a Candidate Drug on HER2, PI3Kalpha, mTOR, hER-alpha, PR, and EGFR Receptors in the Breast Cancer.
33456540 2021. Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review).
33747462 2021. Association of dietary calcium, magnesium, and vitamin D with type 2 diabetes among US adults: National health and nutrition examination survey 2007-2014-A cross-sectional study.
33282857 2020. The Role of Disturbed Mg Homeostasis in Chronic Kidney Disease Comorbidities.
34504502 2021. The Molecular Mechanism of Multiple Organ Dysfunction and Targeted Intervention of COVID-19 Based on Time-Order Transcriptomic Analysis.
31849975 2019. A Biodegradable Mg-Based Alloy Inhibited the Inflammatory Response of THP-1 Cell-Derived Macrophages Through the TRPM7-PI3K-AKT1 Signaling Axis.
34489714 2021. An Insight on Multicentric Signaling of Angiotensin II in Cardiovascular system: A Recent Update.
33959029 2021. The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19.
31572181 2019. Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice.
33296687 2020. Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
29343440 2018. Chanzyme TRPM7 Mediates the Ca(2+) Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
31955624 2020. Molecular regulation of TLR signaling in health and disease: mechano-regulation of macrophages and TLR signaling.
33447739 2019. Association of hypomagnesemia with cardiovascular diseases and hypertension.
33803491 2021. TRP Channels as Cellular Targets of Particulate Matter.
32992944 2020. A Review of the Action of Magnesium on Several Processes Involved in the Modulation of Hematopoiesis.
32698380 2020. Carotid Body and Metabolic Syndrome: Mechanisms and Potential Therapeutic Targets.
31991573 2020. The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis.
32756352 2020. Exploring the Mediators that Promote Carotid Body Dysfunction in Type 2 Diabetes and Obesity Related Syndromes.
30845649 2019. Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators.
30889804 2019. Effects of Magnesium Deficiency on Mechanisms of Insulin Resistance in Type 2 Diabetes: Focusing on the Processes of Insulin Secretion and Signaling.
31284572 2019. The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
31336935 2019. Magnesium Is a Key Player in Neuronal Maturation and Neuropathology.
30995736 2019. TRPM7, Magnesium, and Signaling.
34703991 2021. MR-PheWAS for the causal effects of serum magnesium on multiple disease outcomes in Caucasian descent.
31036759 2019. A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD.
29093028 2018. Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes.
33971585 2021. An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19.
34499925 2021. The Mitochondrial Ca(2+) uniporter is a central regulator of interorganellar Ca(2+) transfer and NFAT activation.
31974165 2020. Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation.
32439805 2020. The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion.
30076216 2018. TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis.
29866880 2018. The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells.
32147957 2020. MiR-9 promotes angiogenesis of endothelial progenitor cell to facilitate thrombi recanalization via targeting TRPM7 through PI3K/Akt/autophagy pathway.
33314296 2021. Association of circulating long non-coding RNA HULC expression with disease risk, inflammatory cytokines, biochemical index levels, severity-assessed scores, and mortality of sepsis.
30819230 2019. TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling.
33571553 2021. Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH.
34045880 2021. The ACE2-Ang-(17)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Mediated NF-small ka, Cyrillicb and MAPK Pathways.
30826804 2019. Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience.
31392789 2019. Frontline Science: Escherichia coli use LPS as decoy to impair neutrophil chemotaxis and defeat antimicrobial host defense.
30861205 2019. Biophysical regulation of macrophages in health and disease.
33481059 2021. Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches.
29383719 2018. CrossTalk proposal: CNNM proteins are Na(+) /Mg(2+) exchangers playing a central role in transepithelial Mg(2+) (re)absorption.
31194171 2019. Diabetes Mellitus Modifies the Associations of Serum Magnesium Concentration With Arterial Calcification and Stiffness in Incident Hemodialysis Patients.
30987399 2019. Magnesium: The Forgotten Electrolyte-A Review on Hypomagnesemia.
31392516 2020. Magnesium-Induced Cell Survival Is Dependent on TRPM7 Expression and Function.
29910176 2018. EMAPII Monoclonal Antibody Ameliorates Influenza A Virus-Induced Lung Injury.
34059671 2021. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.
34001887 2021. TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration.
34112781 2021. TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection.
32415068 2020. The native ORAI channel trio underlies the diversity of Ca(2+) signaling events.
30622345 2019. Calcium signalling in T cells.
31605492 2020. Calciprotein particle inhibition explains magnesium-mediated protection against vascular calcification.
33808247 2021. Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.
34444647 2021. Editorial of Special Issue "Magnesium in Human Health and Disease".
33435521 2021. Magnesium in Infectious Diseases in Older People.
33573164 2021. Magnesium in Aging, Health and Diseases.
33499378 2021. Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes.
30813254 2019. Magnesium: A Magic Bullet for Cardiovascular Disease in Chronic Kidney Disease?
32215176 2020. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1alpha.
32964285 2020. TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity.
30417250 2019. SLC41A1 is essential for magnesium homeostasis in vivo.
34278747 2021. An overview of diagnosis and management of drug-induced hypomagnesemia.
32706793 2020. Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice.
32074140 2020. Microvasculopathy and soft tissue calcification in mice are governed by fetuin-A, magnesium and pyrophosphate.
30615643 2019. TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.
30770447 2019. TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival.
30718434 2019. Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism.
33859252 2021. Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.
32047249 2020. TRPM7 contributes to progressive nephropathy.
33544938 2021. Metabolic sensor O-GlcNAcylation regulates megakaryopoiesis and thrombopoiesis through c-Myc stabilization and integrin perturbation.
32711944 2020. CRAC Channels and Calcium Signaling in T Cell-Mediated Immunity.
32494148 2020. Vascular Calcification: An Important Understanding in Nephrology.

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