coviki.org was constructed in may 2020 at less than 10.000 published papers by pubmed accessibility. it was possible to keep up with human-bassed assortment of papers into subject topics. 2021 is at 62k papers at june 9th and 2020...
I will show here the most remarkable appearing papers as I got noticed at initally screening the pubmed readouts.
| preTAGGED urgent papers 2022 July
2020 intersting papers
anything to be included but not shifted into topics yet
visit the Omics of Covid-19 disease dataset !!!!
35719764 2022. A Longer Quarantine Period May Be Needed for Effective Control of COVID-19 Transmission: Experience From Odisha, India.
35723396 2022. Possibility of SARS-CoV-2 Infection in the Metastatic Microenvironment of Cancer.
35723340 2022. Transcription of the Envelope Protein by 1-L Protein-RNA Recognition Code Leads to Genes/Proteins That Are Relevant to the SARS-CoV-2 Life Cycle and Pathogenesis.
| 35723296 2022. Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line.
35729074 2022. A highly powerful nonspecific strategy to reduce COVID-19 deaths.
35765167 2022. SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
35764775 2022. Temporal changes in the accessory protein mutations of SARS-CoV-2 variants and their predicted structural and functional effects.
35673248 2022. Factors Associated With COVID-19 Breakthrough Infections in Large Midwestern Healthcare System: Implications for Vulnerable Healthcare Personnel.
| 35721801 2022. Liposome encapsulated clodronate mediated elimination of pathogenic macrophages and microglia: A promising pharmacological regime to defuse cytokine storm in COVID-19.
35662523 2022. Impact of vaccination on admissions to an intensive care unit for COVID-19 in a third-level hospital.
35640743 2022. Metformin: Is it a drug for all reasons and diseases?
35695564 2022. Rapid Detection of Bacterial and Fungal Pathogens Using the T2MR versus Blood Culture in Patients with Severe COVID-19.
35638906 2022. Receptor-Binding-Motif-Targeted Sanger Sequencing: a Quick and Cost-Effective Strategy for Molecular Surveillance of SARS-CoV-2 Variants.
35650493 2022. Noch ein innovatives Argument gegen die Covid-Impfung.
35721225 2022. Serum microRNAs targeting ACE2 and RAB14 genes distinguish asymptomatic from critical COVID-19 patients.
35754393 2022. Tuberculosis endemicity and BCG vaccination: Protection against COVID-19.
35701421 2022. An index of access to essential infrastructure to identify where physical distancing is impossible.
35697699 2022. Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19.
35745554 2022. Diagnostic Laboratory Characteristics of COVID-19 Patients Infected by Fomites: COVID-19 Outbreak in a South Korean Public Administrative Facility.
35736648 2022. The Role of Exposomes in the Pathophysiology of Autoimmune Diseases II: Pathogens.
35667761 2022. COVID-19 in Children.
35745615 2022. Analgesics Induce Alterations in the Expression of SARS-CoV-2 Entry and Arachidonic-Acid-Metabolizing Genes in the Mouse Lungs.
35759496 2022. Nitric oxide versus epoprostenol for refractory hypoxemia in Covid-19.
35749400 2022. Non-COVID outcomes associated with the coronavirus disease-2019 (COVID-19) pandemic effects study (COPES): A systematic review and meta-analysis.
35696404 2022. Inequities in the incidence and mortality due to COVID-19 in nursing homes in Barcelona by characteristics of the nursing homes.
35679278 2022. Finding the infectious dose for COVID-19 by applying an airborne-transmission model to superspreader events.
35700214 2022. Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2.
35702711 2022. Public-making in a pandemic: The role of street art in East African countries.
35694714 2022. Cytokine storm promoting T cell exhaustion in severe COVID-19 revealed by single cell sequencing data analysis.
35727979 2022. Hybrid measurement of respiratory aerosol reveals a dominant coarse fraction resulting from speech that remains airborne for minutes.
35700355 2022. SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis.
35763573 2022. The dynamics of SARS-CoV-2 infectivity with changes in aerosol microenvironment.
| 35749382 2022. Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction.
35694109 2022. Pandemetrics: systematically assessing, monitoring, and controlling the evolution of a pandemic.
35709537 2022. On the origin of nitrosylated hemoglobin in COVID-19: Endothelial NO capture or redox conversion of nitrite?: Experimental results and a cautionary note on challenges in translational research.
35765493 2022. In vivo test of Vibrio alginolyticus and Vibrio harveyi infection in the humpback grouper (Cromileptes altivelis) from East Java Indonesia.
35705446 2022. Repairing moral injury takes a team: what clinicians can learn from combat veterans.
| 35641108 2022. The putative mechanism of lymphopenia in COVID-19 patients.
35680418 2022. In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients - A First-In-Human Positron Emission Tomography Study with (11)C-GW457427.
| 35729709 2022. Nanoligomers Targeting Human miRNA for the Treatment of Severe COVID-19 Are Safe and Nontoxic in Mice.
35662001 2022. Molecular signaling pathways, pathophysiological features in various organs, and treatment strategies in SARS-CoV2 infection.
35748162 2022. TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
35723762 2022. Microvascular and proteomic signatures overlap in COVID-19 and bacterial sepsis: the MICROCODE study.
35693100 2022. Real world data speak a different language about the outcome of pregnancies undergoing SARS-CoV-2 vaccinations.
35737122 2022. Current RT-qPCR to detect SARS-CoV-2 may give positive results for related coronaviruses.
| 35709650 2022. Treatment with metformin glycinate reduces SARS-CoV-2 viral load: An in vitro model and randomized, double-blind, Phase IIb clinical trial.
35740360 2022. Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation-A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients.
35740354 2022. Unbalanced IDO1/IDO2 Endothelial Expression and Skewed Keynurenine Pathway in the Pathogenesis of COVID-19 and Post-COVID-19 Pneumonia.
| 35661911 2022. The significance of surface neutrophilic MPO expression level in NETosis and NETosis-associated coagulopathies in covid-19 infected patients.
35766682 2022. Comment on "Diagnostic and prognostic significance of long noncoding RNA LINC00173 in patients with melanoma".
35670286 2022. Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany.
35658040 2022. Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees.
| 35710807 2022. Protective Policy Index (PPI) global dataset of origins and stringency of COVID 19 mitigation policies.
| 35697698 2022. A database of anti-coronavirus peptides.
| 35650205 2022. CoV2K model, a comprehensive representation of SARS-CoV-2 knowledge and data interplay.
35680931 2022. Elevated plasma level of the glycolysis byproduct methylglyoxal on admission is an independent biomarker of mortality in ICU COVID-19 patients.
35676404 2022. Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19.
| 35760825 2022. A unique antigen against SARS-CoV-2, Acinetobacter baumannii, and Pseudomonas aeruginosa.
35729319 2022. High generation of reactive oxygen species from neutrophils in patients with severe COVID-19.
35725585 2022. COVID-19 conspiracy ideation is associated with the delusion proneness trait and resistance to update of beliefs.
35654986 2022. The impact of the suppression of highly connected protein interactions on the corona virus infection.
| 35654869 2022. Nudging societally relevant behavior by promoting cognitive inferences.
35717436 2022. Relating SARS-CoV-2 variants using cellular automata imaging.
| 35709649 2022. COVID-19 associated pediatric vasculitis: A systematic review and detailed analysis of the pathogenesis.
35764457 2022. Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15).
35664444 2022. Vaccine Toes Are the New COVID Toes.
35649522 2022. Continued Visibility of COVID-19 Article Removals.
35716662 2022. Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
35669179 2022. Affectivity, subjectivity, and vulnerability: on the new forces of mass hysteria.
35702316 2022. The use of the Dark Web as a COVID-19 information source: A three-country study.
35664076 2022. The interplay between lncRNAs, RNA-binding proteins and viral genome during SARS-CoV-2 infection reveals strong connections with regulatory events involved in RNA metabolism and immune response.
35736914 2022. Exacerbation of Fatality Rates Induced by Poor Air Quality Due to Open-Air Mass Funeral Pyre Cremation during the Second Wave of COVID-19.
35746462 2022. How Were Healthcare Workers after Anti-SARS-CoV-2 Vaccination? A Study of the Emotional Side Effects of Vaccination.
35746443 2022. A Disproportionality Analysis for Association of Systemic Capillary Leak Syndrome with COVID-19 Vaccination Using the World Health Organization Pharmacovigilance Database.
| 35746588 2022. Broad Cross-Reactive IgA and IgG against Human Coronaviruses in Milk Induced by COVID-19 Vaccination and Infection.
35746544 2022. Reduction of Precautionary Behaviour following Vaccination against COVID-19: A Test on a British Cohort.
35698151 2022. Ivermectin under scrutiny: a systematic review and meta-analysis of efficacy and possible sources of controversies in COVID-19 patients.
35746657 2022. Carriers of ADAMTS13 Rare Variants Are at High Risk of Life-Threatening COVID-19.
35746613 2022. Autoimmune Effect of Antibodies against the SARS-CoV-2 Nucleoprotein.
35671104 2022. Platypnea-orthodeoxia syndrome in SARS-CoV-2 related ARDS: a case report.
35671465 2022. Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and ARDS.
35649173 2022. COVID-19-Associated Lung Microvascular Endotheliopathy: A "From the Bench" Perspective.
35729072 2022. The Life of SARS-CoV-2 Inside Cells: Replication-Transcription Complex Assembly and Function.
35316662 2022. Highly effective rheumatoid arthritis therapy by peptide-promoted nanomodification of mesenchymal stem cells.
35667680 2022. Covid-19: Doctor who sold hydroxychloroquine as "magic bullet" treatment is jailed.
| 35764342 2022. How long does SARS-CoV-2 stay in the body?
35688473 2022. Covid-19: Unusable PPE worth pound4bn will be burned, says spending watchdog.
35732270 2022. Anti-glutathione S-transferase omega 1-1 (GSTO1-1) antibodies are increased during acute and chronic inflammation in humans.
35754264 2022. ADAMTS13 factor deficiency in severe COVID-19 may not be immune mediated-report from a pilot study.
35655148 2022. CoQUAD: a COVID-19 question answering dataset system, facilitating research, benchmarking, and practice.
35717168 2022. The contribution of hospital-acquired infections to the COVID-19 epidemic in England in the first half of 2020.
35689192 2022. Decreased survival in children inpatients with COVID-19 and antibiotic prescription.
35764965 2022. Helminth antigens differentially modulate the activation of CD4(+) and CD8(+) T lymphocytes of convalescent COVID-19 patients in vitro.
35655307 2022. Expediting knowledge acquisition by a web framework for Knowledge Graph Exploration and Visualization (KGEV): case studies on COVID-19 and Human Phenotype Ontology.
| 35765042 2022. Analysis of 4 cases of children with false-positive results of novel coronavirus-specific antibody.
35659285 2022. A database of US state policies to mitigate COVID-19 and its economic consequences.
35768139 2022. Long distance airborne transmission of SARS-CoV-2: rapid systematic review.
35667740 2022. COVID-19 Acute Respiratory Distress Syndrome: One Pathogen, Multiple Phenotypes.
| 35695606 2022. PD-L1 Overexpression in the Lungs of Subjects Who Died from COVID-19: Are We on the Way to Understanding the Immune System Exhaustion Induced by SARS-CoV-2?
| 35762551 2022. Targeting and Modulation of the Natriuretic Peptide System in Covid-19: A single or double-edged effect?
remember: entresto targets trpm7 !!!!!
35762585 2022. An unethical trial and the politicization of the COVID-19 pandemic in Brazil: The case of Prevent Senior.
| 35689332 2022. COVID-19 rapidly increases MDSCs and prolongs innate immune dysfunctions.
35672040 2022. Great escape: how infectious SARS-CoV-2 avoids inactivation by gastric acidity and intestinal bile.
35658753 2022. Putting Emotions in the Health Belief Model: The Role of Hope and Anticipated Guilt on the Chinese's Intentions to Get COVID-19 Vaccination.
35686754 2022. [Concentration Variation and Source Analysis of Metal Elements in PM2.5 During COVID-19 Control in Suzhou].
35686753 2022. [Influence of COVID-19 Prevention and Control Measures on PM2.5 Concentration, Particle Size Distribution, Chemical Composition, and Source in Zhengzhou, China].
35752871 2022. Tissue immunity to SARS-CoV-2: Role in protection and immunopathology.
35765578 2022. Explosive outbreak of SARS-CoV-2 Omicron variant is associated with vertical transmission in high-rise residential buildings in Hong Kong.
35709328 2022. Preferential uptake of SARS-CoV-2 by pericytes potentiates vascular damage and permeability in an organoid model of the microvasculature.
35685064 2022. Transient Complete Recovery of Chronic Refractory Idiopathic Thrombocytopenic Purpura after Treatment with Monoclonal Antibody Targeting SARS-CoV-2 Spike Protein.
35715738 2022. SARS-CoV-2: phenotype, genotype, and characterization of different variants.
35732914 2022. SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1.
35708858 2022. Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19.
35675811 2022. Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles.
35675822 2022. Mature neutrophils and a NF-kappaB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19.
| 35741045 2022. The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2.
35729310 2022. Use of rituximab in SARS-CoV-2-positive renal transplant recipient with EBV reactivation and probable haemophagocytic lymphohistiocytosis.
35663505 2022. COVID-19-inspired "artificial virus" to combat drug-resistant bacteria by membrane-intercalation- photothermal-photodynamic multistage effects.
35688196 2022. Critical role of Hyssop plant in the possible transmission of SARS-CoV-2 in contaminated human Feces and its implications for the prevention of the virus spread in sewage.
| 35714708 2022. Neutrophil Extracellular Traps, Local IL-8 Expression, and Cytotoxic T-Lymphocyte Response in the Lungs of Patients With Fatal COVID-19.
35757923 2022. Natural and genetically-modified animal models to investigate pulmonary and extrapulmonary manifestations of COVID-19.
35760647 2022. The 2022 outbreak and the pathobiology of the monkeypox virus.
35602240 2022. Online citizen petitions related to COVID-19 in South Korean cities: a big data analysis.
35602931 2022. Raging Against the "Neoliberal Hellscape": Anger, Pride, and Ambivalence in Civil Society Responses to the COVID-19 Pandemic in the USA.
35577481 2022. Facebook recruitment for research of children and parents during the COVID-19 pandemic.
35625719 2022. Characterization of the Upper Respiratory Bacterial Microbiome in Critically Ill COVID-19 Patients.
35596137 2022. A compelling demonstration of why traditional statistical regression models cannot be used to identify risk factors from case data on infectious diseases: a simulation study.
35618306 2022. The unintended consequences of COVID-19 vaccine policy: why mandates, passports and restrictions may cause more harm than good.
35588018 2022. Inhibition of IRAK4 dysregulates SARS-CoV-2 spike protein-induced macrophage inflammatory and glycolytic reprogramming.
35594413 2022. Methodology-Centered Review of Molecular Modeling, Simulation, and Prediction of SARS-CoV-2.
35717660 2022. Increased deaths from fungal infections during the COVID-19 pandemic-National Vital Statistics System, United States, January 2020-December 2021.
35572363 2022. Potential reversal of pulmonary vasoplegia by inhaled ibuprofenate in COVID-19 pneumonia.
| 35573165 2022. Off-target effects of bacillus Calmette-Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19.
35696527 2022. Human-host transcriptomic analysis reveals unique early innate immune responses in different sub-phenotypes of COVID-19.
| 35725000 2022. Study authors don't consider waning SARS-CoV-2 immunity after vaccination in their model.
35687925 2022. Integrated COVID-19 Predictor: Differential expression analysis to reveal potential biomarkers and prediction of coronavirus using RNA-Seq profile data.
| 35582691 2022. The COVID-19 High-Performance Computing Consortium.
35574268 2022. Reconstruction of the origin of the first major SARS-CoV-2 outbreak in Germany.
35602928 2022. Multifaceted membrane binding head of the SARS-CoV-2 spike protein.
35626407 2022. Cerebral Venous Thrombosis after SARS-CoV-2 Infection and Pfizer-BioNTech Vaccination against COVID-19.
35594828 2022. Air pollution might affect the clinical course of COVID-19 in pediatric patients.
35626609 2022. Information Dynamics of Electric Field Intensity before and during the COVID-19 Pandemic.
35626506 2022. Application of Coarse-Grained (CG) Models to Explore Conformational Pathway of Large-Scale Protein Machines.
35580710 2022. The association of airborne particulate matter and benzo[a]pyrene with the clinical course of COVID-19 in patients hospitalized in Poland.
35611340 2022. Methods to evaluate vascular function: a crucial approach towards predictive, preventive, and personalised medicine.
35618891 2022. Host genetic basis of COVID-19: from methodologies to genes.
35585256 2022. Intestinal microbiota composition of children with infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and multisystem inflammatory syndrome (MIS-C).
35618037 2022. Type-I interferons in the immunopathogenesis and treatment of Coronavirus disease 2019.
35595312 2022. Genetic overlap between idiopathic pulmonary fibrosis and COVID-19.
35587090 2022. Type-H, and Type-L COVID-19: are they different subtypes or the same?
35587087 2022. Clinical characteristics and treatments of multi-system inflammatory syndrome in children: a systematic review.
35611122 2022. COVID-19 malicious domain names classification.
35596115 2022. Disease-associated dysbiosis and potential therapeutic role of Akkermansia muciniphila, a mucus degrading bacteria of gut microbiome.
35592407 2022. Serial Cardiovascular Magnetic Resonance Studies Prior to and After mRNA-Based COVID-19 Booster Vaccination to Assess Booster-Associated Cardiac Effects.
35573668 2022. Reticulophagy Reprograms the Endoplasmic Reticulum for SARS-CoV-2 Replication.
35602853 2022. Secondary Traumatic Stress and Moral Injury in Maternity Care Providers: A Narrative and Exploratory Review.
35603169 2022. Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2.
35585976 2022. Seroreactivity of the Severe Acute Respiratory Syndrome Coronavirus 2 Recombinant S Protein, Receptor-Binding Domain, and Its Receptor-Binding Motif in COVID-19 Patients and Their Cross-Reactivity With Pre-COVID-19 Samples From Malaria-Endemic Areas.
| 35572540 2022. Myeloid-Derived Suppressor Cells in COVID-19: The Paradox of Good.
| 35627104 2022. mRNA Vaccines: Why Is the Biology of Retroposition Ignored?
35574937 2022. A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2.
35587319 2022. Suppressing Scientific Discourse on Vaccines? Self-perceptions of researchers and practitioners.
35604493 2022. A systematic review on neutrophil extracellular traps and its prognostication role in COVID-19 patients.
35615983 2022. A nucleic acid amplification test-based strategy does not help inform return to work for healthcare workers with COVID-19.
35604387 2022. Realigning the LIGHT signaling network to control dysregulated inflammation.
35622346 2022. The COVID-19 pandemic: SARS-CoV-2, childhood hepatitis and monkeypox raise five new questions for the global health research community.
35604059 2022. When the "heroes" "don't feel cared for": The migration and resignation of Philippine nurses amidst the COVID-19 pandemic.
35585856 2021. Mental health of the adult population in Germany during the COVID-19 pandemic. Rapid Review.
35606065 2022. High torque tenovirus (TTV) load before first vaccine dose is associated with poor serological response to COVID-19 vaccination in lung transplant recipients.
35623468 2022. COVID-19 vaccination strategy for hospital staff in Germany: a cross-sectional study in March-April 2021.
35594984 2022. SARS-CoV-2 detection on healthcare workers' hands caring for COVID-19 patients.
35590139 2021. Mammalian enteral ventilation ameliorates respiratory failure.
35621124 2022. Pathogenesis of pneumonia and acute lung injury.
35598178 2022. Autoantibodies against apolipoprotein A-1 after COVID-19 predict symptoms persistence.
35599487 2022. COVID-19 and Neurodegenerative Diseases: Prion-Like Spread and Long-Term Consequences.
35603834 2022. SARS-CoV-2 Infection Dysregulates Host Iron (Fe)-Redox Homeostasis (Fe-R-H): Role of Fe-Redox Regulators, Ferroptosis Inhibitors, Anticoagulants, and Iron-Chelators in COVID-19 Control.
35768188 2022. Association between democratic governance and excess mortality during the COVID-19 pandemic: an observational study.
35713638 2022. Fighting a Plague: Doctors' Stories of Challenge and Innovation Combatting the AIDS Epidemic in 1980s New York City.
| 35612378 2022. How forced dichotomization hijacked meaningful debate during the COVID-19 pandemic.
35758987 2022. Anti-membrane antibodies persist at least one year and discriminate between past COVID-19 infection and vaccination.
35580331 2022. Effect of an Amyloidogenic SARS-COV-2 Protein Fragment on alpha-Synuclein Monomers and Fibrils.
35583898 2022. SARS-CoV-2 RNA Can Persist in Stool Months After Respiratory Tract Clears Virus.
35585793 2022. Guidance in the chaos: Effects of science communication by virologists during the COVID-19 crisis in Germany and the role of parasocial phenomena.
35617417 2022. Engineered tomatoes get a healthy dose of vitamin D.
35573750 2022. Mechanisms underlying inactivation of SARS-CoV-2 by nano-sized electrostatic atomized water particles.
35629250 2022. A Single Session of Virtual Reality Improved Tiredness, Shortness of Breath, Anxiety, Depression and Well-Being in Hospitalized Individuals with COVID-19: A Randomized Clinical Trial.
| 35593652 2022. Hijacking of Cellular Functions by Severe Acute Respiratory Syndrome Coronavirus-2. Permeabilization and Polarization of the Host Lipid Membrane by Viroporins.
| 35608920 2022. Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses.
35575761 2022. Let's color: An online coloring game improves subjective well-being and reduces anxiety during the COVID-19 pandemic.
| 35576952 2022. Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens.
| 35629310 2022. Chronic Exposure to the Food Additive tBHQ Modulates Expression of Genes Related to SARS-CoV-2 and Influenza Viruses.
35587188 2022. Circulatory Exosomes from COVID-19 Patients Trigger NLRP3 Inflammasome in Endothelial Cells.
| 35611874 2022. AntiV-SGN: a universal antiviral strategy to combat both RNA and DNA viruses by destroying their nucleic acids without sequence limitation.
| 35579467 2022. Super Dominant Pathobiontic Bacteria in the Nasopharyngeal Microbiota Cause Secondary Bacterial Infection in COVID-19 Patients.