Percom pruritus

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minibibliographie zur frage der behandlung des pruritus mit dem alten kappa agonisten nalbuphin


9370866 1997. Nalbuphine and pruritus
9203908 1997. Nalbuphine and pruritus
30484997 2022. Nalbuphine

25885112 2015. Pharmacokinetics of nalbuphine hydrochloride extended release tablets in hemodialysis patients with exploratory effect on pruritus
31568781 2019. Nalbuphine, a kappa opioid receptor agonist and mu opioid receptor antagonist attenuates pruritus, decreases IL-31, and increases IL-10 in mice with contact dermatitis
35497636 2022. Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implications
34576988 2021. Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic
29253847 2017. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Nalbuphine ER Tablets for Uremic Pruritus
29929599 2018. End-Stage Renal Disease Chronic Itch and Its Management


20951695 2011. Clonidine inhibits itch-related response through stimulation of alpha(2)-adrenoceptors in the spinal cord in mice

30426802 2018. Novel drugs for the treatment of chronic pruritus
33296031 2022. Antipruritic Effects of Kappa Opioid Receptor Agonists: Evidence from Rodents to Humans
25861786 2015. Targeting Itch with Ligands Selective for kappa Opioid Receptors
34780095 2022. Efficacy and safety of oral nalbuphine extended release in prurigo nodularis: results of a phase 2 randomized controlled trial with an open-label extension phase

die meisten papers im perioperativen setting bei opiat-nw, hier nicht dargestellt.

in begrenzter indikation dialysepatienten mit ausschluß anderer ätiologie renalem pruritus demnächst i.v. difelikefalin, andere anwendung in fachinfo höflichst nicht erwünscht.

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