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K (Candidate Compounds Covid19)
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'''the topic map of a 30 kB genome'''
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'''coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.'''
  
== Further reading ==
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{{tp|p=32399342|t=2020. A Case of a COVID-19-positive Patient.|pdf=|usr=008}}
*[http://www.moremed.org/SiteSearch.php?S1=%28covid19+OR+covid-19+OR+covid19+OR+sars-cov2+OR+sars-cov-2+OR+2019-ncov+OR+2019ncov%29&S2=&S3=&submit=submit&px1=proxy.nationallizenzen.de&px2=&px3=&px4=&R=all&Y0=1500&Y1=2025 search pubmed and other resources]
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*[[journal publishers collections]]
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*[[ppl who want to hear your ideas on covid19]]
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*[[discussion groups covid19]]
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*[[PubMed selected papers unsorted to be listed in contents topics]]
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== general reviews covid19 disease ==
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{{dNEJMLancet}}
{{tp|p=32150360|t=2020. Features, Evaluation and Treatment Coronavirus (COVID-19)|pdf=|usr=}}
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== structure covid19==
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visit '''[http://www.coviki.org this websites homepage]''' to get
 +
an expert 3d view on the topics as i assorted them retrospectively
 +
the 3fold separation of the clinical issues is not well
 +
reflected by this or the navigation list.
 +
since dynamic modifable tables are hard to implement
 +
in old wikimeda application its on a simple html page
  
'''genomic variablity'''
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__NOTOC__
*[https://www.sciencedirect.com/science/article/pii/S1567134820301829 ...is high]
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== Covid19 target binding and uptake ==
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*'''[[PreTAGGED urgent papers]]''' top useful papers entered immediately after reading the actual pubmed list.
  
== Covid19 cytopathic effects ==
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*'''[[TRPM7 2024]]''' Magnesium was my needle in the haystack 02/2020 so I will review the most important Magnesium channel here.
  
== Covid19 innate sensing ==
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*'''[[Further reading]]'''
  
== Covid19 local tissue reaction ==
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*'''[[Unproven ideas]] the best-of section'''
  
*[https://www.cell.com/action/showPdf?pii=S1074-7613%2820%2930183-7 rev. on covid immunology]
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*'''[[Reviews on covid19 disease]]'''
  
== Covid19 cytokine storm | hemophagocytic lymphohistiocytosis hlh==
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*'''[[Children with covid19 disease]]''' Infants see Pregnancy
*[https://www.standard.co.uk/news/uk/children-hyper-inflammatory-disease-coronavirus-a4434636.html on hlh]
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{{tp|p=32267081|t=2020. Continuous Intravenous Anakinra Infusion to Calm the Cytokine Storm in Macrophage Activation Syndrome |pdf=|usr=}}
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{{tp|p=32267072|t=2020. IV anakinra for macrophage activation syndrome may hold lessons for treatment of  cytokine storm in the setting of COVID19 |pdf=|usr=}}
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== Covid19 ARDS ==
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*'''[[Clinical guidelines and advice]]'''
  
== pulmonary embolism / coagulation covid19==
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*'''[[Respiration mgmt]]'''
*[https://townhall.com/tipsheet/leahbarkoukis/2020/05/05/doctors-are-noticing-a-dangerous-phenomenon-even-after-wuhan-coronavirus-symptoms-are-gone-n2568192 thrombotic late reactions]
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*[https://www.welt.de/wissenschaft/video207855067/Obduktionen-Corona-Patienten-sterben-haeufig-an-Blutgerinnseln.html german autopsy data]
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{{tp|p=32331965|t=ä. Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach |pdf=|usr=}}
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== heart covid19==
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*'''[[Diagnosis (Laboratory)]]'''
{{tp|p=32310612|t=2020. Cardiac Manifestations Of Coronavirus (COVID-19)|pdf=|usr=}}
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== neurology, ophthalmology, orl covid19 ==
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*'''[[Diagnosis (Lung CT, Sonography)]]'''
{{tp|p=32310553|t=2020. Ophthalmic Manifestations Of Coronavirus (COVID-19)|pdf=|usr=}}
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{{tp|p=32119409|t=2020. Neuroanatomy, Nucleus Gustatory|pdf=https://www.ncbi.nlm.nih.gov/books/NBK554522/#article-36422.s6|usr=}}
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{{tp|p=32295727|t=ä. Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report |pdf=|usr=}}
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{{tp|p=32343122|t=2020. Updates on What ACS Reported: Emerging Evidences of COVID-19 with Nervous System  Involvement |pdf=|usr=}}
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{{tp|p=32320211|t=ä. Neurological Insights of COVID-19 Pandemic |pdf=|usr=}}
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{{tp|p=C7160911|t=ä. SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples  Allowing Earlier Virus Detection |pdf=|usr=}}
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{{tp|p=32348111|t=ä. Is the Collapse of the Respiratory Center in the Brain Responsible for Respiratory Breakdown in COVID-19 Patients?|pdf=|usr=}}
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{{tp|p=32167747|t=2020. Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host?Virus Interaction, and Proposed Neurotropic Mechanisms |pdf=|usr=}}
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{{tp|p=32233443|t=2020. Letter to the Editor ...Evidence of the COVID-19 Virus Targeting the CNS... |pdf=|usr=}}
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== Covid19 hypoxia tolerance ==
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*'''[[Diagnosis (other modalities)]]'''
*[http://archive.is/VTqtr happy hypoxia experience]
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== Covid19 putative risk factors ==
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----
  
*[https://www.boston25news.com/news/health/high-blood-pressure-drugs-cleared-covid/UC5LTCKKKVDETBWKJDZ2P776XY/ ACEI/AT1RA not risky ?]
 
*[https://theconversation.com/we-found-and-tested-47-old-drugs-that-might-treat-the-coronavirus-results-show-promising-leads-and-a-whole-new-way-to-fight-covid-19-136789 dextrometorphan (antitussive compd)]
 
  
== Covid19 secretion ==
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*'''[[Structure of covid19]]'''
  
 +
*'''[[Target binding and uptake]]'''
  
 +
*'''[[Cytopathic effects]]'''
  
== anything MERS ==
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*'''[[Secretion and shedding]]'''
  
== anything SARS ==
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*'''[[Innate sensing]]'''
  
== anything Influenza ==
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*'''[[Immunology]]'''
  
== anything Influenza 1918 ==
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*'''[[Cytokine storm, hemophagocytic lymphohistiocytosis, macrophage activation syndrome]]'''
*[https://www.history.com/news/spanish-flu-second-wave-resurgence history.com]
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----
 +
*'''[[Pathobiology]]'''
  
== anything Ebola ==
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*'''[[Disease Models]]'''
  
== Pathobiology Covid19==
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*'''[[Similar diseases and pathomechanisms]]'''
{{tp|p=32273135|t=ä. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases |pdf=|usr=}}
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----
  
== Disease Models Covid19 ==
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*'''[[Early symptoms]]'''
  
== Diagnosing (Virus / Antibodies) Covid19 ==
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*'''[[Systemic disease, any manifestations]]'''
*[https://archive.fo/61OpY on false-positives]
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*[https://www.aljazeera.com/news/2020/05/tanzania-covid-19-lab-head-suspended-president-questions-data-200505065136872.html on positives in non-vertebrate samples]
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*[https://www.wsj.com/articles/roche-coronavirus-antibody-test-wins-fda-approval-for-emergency-use-11588505019 antibody test roche]
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== Diagnosing (Lung CT, Sonography) Covid19 ==
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*'''[[Co-Infection]]'''
{{tp|p=32276754|t=ä. CT Manifestation of COVID-19 Pneumonia; Role of Multiplanar Imaging |pdf=|usr=}}
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{{tp|p=32204990|t=2020. Imaging Features of Coronavirus disease 2019 (COVID-19): Evaluation on Thin-Section CT |pdf=|usr=}}
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{{tp|p=32204987|t=2020. Coronavirus Disease (COVID-19): Spectrum of CT Findings and Temporal Progression  of the Disease |pdf=|usr=}}
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{{tp|p=32335002|t=ä. COVID-19 Evaluation by Low-Dose High Resolution CT Scans Protocol |pdf=|usr=}}
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{{tp|p=32331965|t=ä. Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach |pdf=|usr=}}
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{{tp|p=32327295|t=ä. COVID-19 or Pulmonary Contusion? A Diagnostic Dilemma |pdf=|usr=}}
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{{tp|p=32312654|t=ä. COVID-19 Pulmonary Involvement: Is Really an Interstitial Pneumonia?|pdf=|usr=}}
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 +
*'''[[Pulmonary embolism, coagulation]]'''
  
== Clinical Guidelines Covid19 ==
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*'''[[Hematology]]'''
  
== Clinical Trials Covid19 ==
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*'''[[Heart]]'''
  
*[https://clinicaltrials.gov/ct2/results?cond=COVID-19 at clinicaltrials.gov 1323 running]
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*'''[[Neurology, ophthalmology, orl]]'''
  
== Candidate Compounds Covid19 ==
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*'''[[Dermatology]]'''
  
'''reviews candidate compounds covid19'''
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*'''[[Gastroenterology, hepatology]]''' and endocrinology and diabetes
{{tp|p=32226821|t=2020. Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases |pdf=|usr=}}
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'''Hydroxychloroquine''' retarget
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*'''[[Kidney, urology]]''' and gynecology/obstetrics
*check retina status known toxicity
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*[https://justthenews.com/politics-policy/coronavirus/doctors-find-hydroxychloroquin-success-rate-91-urge-arizona-maybe-make 91% benefit]
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*[https://www.themoscowtimes.com/2020/04/17/russia-approves-unproven-malaria-drug-to-treat-coronavirus-a70025 approval russia]
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*[https://m.timesofindia.com/business/india-business/covid-19-68-new-companies-get-fdca-permit-to-make-hcq/amp_articleshow/75566317.cms scale up production]
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*[https://www.medrxiv.org/content/10.1101/2020.04.26.20081059v1.full.pdf+html on safety, trial]
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 +
*'''[[Risk and special populations]]'''
  
'''Chlorpromazine''' retarget
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*'''[[Case reports]]'''
*[https://www.biorxiv.org/content/10.1101/2020.05.05.079608v1 paper]
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'''Zinc''' add-on
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*'''[[Case series]]'''
*[https://www.sciencedirect.com/science/article/pii/S0306987720306435 call for trial]
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'''Remdesivir''' retarget
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*'''[[Registries]]'''
*[https://gab.com/Remnant601/posts/104122987152232660 one hospital on...]
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'''Lauric acid''' nat. compd.
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*'''[[The morbid survivor]]'''
*[https://www.icp.org.ph/2020/01/the-potential-of-coconut-oil-and-its-derivatives-as-effective-and-safe-antiviral-agents-against-the-novel-coronavirus-ncov-2019/ call for trial]
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----
  
'''Nicotine''' nat. toxin
 
*[https://www.usatoday.com/story/news/factcheck/2020/05/03/covid-19-fact-check-caution-urged-study-virus-smoking/3055378001/ france]
 
  
'''Niclosamide'''
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*'''[[Trials]]'''
{{tp|p=32125140|t=ä. Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential |pdf=|usr=}}
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'''Various Leads'''
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*'''[[Candidate Compounds Covid19]]'''
*[https://theconversation.com/we-found-and-tested-47-old-drugs-that-might-treat-the-coronavirus-results-show-promising-leads-and-a-whole-new-way-to-fight-covid-19-136789 9 retargeted: ternatin4, zotatifin, plitidepsin; haloperidol, melperone, clemastine, cloperastine, pb28, progesterone]
+
----
*[https://doi.org/10.1038/s41586-020-2286-9 paper in nature]
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== hope: Vaccination Covid19 ==
 
  
*[https://patch.com/massachusetts/cambridge/ma-company-takes-critical-step-toward-covid-19-vaccine mrna-1273, moderna]
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*'''[[Remission, recurrence and persistence]]'''
  
== hope: Therapeutic antibodies ==
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*'''[[Other routes of infection]]'''
*[https://www.foxnews.com/science/man-made-antibody-neutralizes-coronavirus-first-time anti covid mab]
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*[https://www.telegraaf.nl/nieuws/750205601/nederlands-antilichaam-47-d11-blokkeert-infectie-coronavirus acmab 47d11]
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== hope: Chemoprevention Covid19 ==
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*'''[[Biophysics of aerosols]]'''
  
== hope: Antiviral agents Covid19 ==
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*'''[[Passive protective equipment]]'''
  
== hope: Lung regeneration and repair after Covid19 ==
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*'''[[Running your hospital]]'''
 +
----
 +
*'''new umbrella page [[Politics main page]]'''
  
== hope: Neurology rehab ==
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*'''[[Mental aspects of health professionals]]'''
  
== Remission & Recurrence ==
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*'''[[Socio-psychiatric aspects of the status hygienicus]]'''
*[https://www.livemint.com/news/india/coronavirus-5-to-15-of-covid-19-patients-fall-sick-again-says-china-study-11588855774537.html 10% recurrence rate]
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== Risk group : Nursing home inmates==
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*''[[Avoiding clinical medicine in other diseases]]''
*[https://justthenews.com/politics-policy/coronavirus/doctors-find-hydroxychloroquin-success-rate-91-urge-arizona-maybe-make no sunlight no vitamin d]
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== Biophysics of aerosols ==
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*''[[Occupational medicine, workplace security and status hygienicus]]''
  
== Aerosolic infection prevention ==
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*''[[Economic aspects of the status hygienicus]]''
  
== Other routes of infection ==
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*''[[Educational aspects of the status hygienicus]]''
 +
----
  
*[https://www.dailymail.co.uk/news/article-8296937/Coronavirus-semen-study-shows.html semen]
 
  
== Socio-psychiatric aspects of the status hygienicus ==
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*'''[[Origin of Covid19]]'''
  
== Economic aspects of the status hygienicus ==
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*'''[[Host, vector, one health, atmospheric aspects]]'''
  
== Educational aspects of the status hygienicus ==
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*'''[[Epidemiology]]'''
  
== Safer Work and status hygienicus ==
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*''[[Failure of politics and public health guidance]]''
  
jail, abattoirs... crowded indoor places...
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*''[[Failure of executive measures]]''
 +
----
  
== Running your hospital ==
 
  
{{tp|p=32303440|t=2020. Radiology Management and COVID-19 in Resource Limited Setting |pdf=|usr=}}
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*''[[Political abuse of Covid19]]''
{{tp|p=32336647|t=ä. COVID-19 Protection Guidelines in Outpatient Medical Imaging Centers |pdf=|usr=}}
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{{tp|p=32335003|t=ä. Proposed imaging guidelines for pregnant women suspected of having COVID-19 |pdf=|usr=}}
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{{tp|p=32113880|t=ä. Corona Virus International Public Health Emergencies: Implications for Radiology  Management |pdf=|usr=}}
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== Host, Vector, One Health aspects of Covid19 ==
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*''[[Lost people]]''
  
== Tracing the Origin of Covid19 ==
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*'''[[History of covid19 exploration]]'''
 +
-----
  
== Mass Psychology of Covid19 ==
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*'''[[misc.]]'''
*[https://gab.com/1001cutz/posts/104129141050204606 positives bannend from military]
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'''social deprivation, suicide'''
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*'''[[Research tools]]'''
*[https://www.breitbart.com/health/2020/05/07/report-suicide-rise-from-lockdowns-to-kill-more-than-coronavirus-in-australia/ inc suicide]
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== Getting Criminal ==
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*'''[[from the ads]]'''
*[https://www.nbcphiladelphia.com/news/coronavirus/researcher-on-verge-of-making-very-significant-virus-findings-shot-to-death/2386375/ reasearcher killed]
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== Transformation of the World accepting and abusing the Virus Thread ==
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*'''[[Current state of coviki.org]]'''
  
== After civilization breakdown ==
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{{Searchtermcov}}
*[https://www.elizabethblog.com.ng/2020/05/were-facing-double-pandemic-un-body.html famine]
+
 
+
== KIA ==
+
*[https://www.breitbart.com/politics/2020/05/04/colorado-medic-assist-nyc-dies-coronavirus/ Paul Cary]
+

Aktuelle Version vom 22. Januar 2024, 10:35 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.


32399342 2020. A Case of a COVID-19-positive Patient.

DISCLAIMER the current scientific record is full of falsified and invented data and subject to political abuse. I cannot keep up with the daily retractions, so do not apply any thesis or hypothesis shown here as a valid option for application to human beings.

visit this websites homepage to get 
an expert 3d view on the topics as i assorted them retrospectively
the 3fold separation of the clinical issues is not well 
reflected by this or the navigation list.
since dynamic modifable tables are hard to implement
in old wikimeda application its on a simple html page


  • TRPM7 2024 Magnesium was my needle in the haystack 02/2020 so I will review the most important Magnesium channel here.














search for covid papers via moremed.org: bc illicit search term expansion with neglect of "" function by pubmed, 2019-ncov OR 2019ncov has to be eliminated from the search term since dec /2021


  • ("mg2+" OR "mg(2+)" OR magnesium OR hypomagnesi* OR hypermagnesi* OR mgcl2 OR trpm7 OR ltrpc7 OR trp-plik OR trpm6 OR transient receptor potential m7 OR transient receptor potential m6 OR chanzyme OR arl15 OR magt1 OR cnnm1 OR cnnm2 OR acdp1 OR acdp2 OR cnnm3 OR cnnm4 OR cyclin-m1 OR cyclin-m2 OR cyclin-m3 OR cyclin-m4 OR "cyclin m1" OR "cyclin m2" OR "cyclin m3" OR "cyclin m4" OR slc41a1 OR slc41a2 OR slc41a3 OR mgte OR solute carrier protein 41 OR nipa1 OR spg6 OR nipa2 OR huntingtin1 OR hip14 OR hip14l OR prl-1 OR prl-2 OR prl-3 OR ptp4a1 OR ptp4a2 OR ptp4a3 OR micu-1 OR micu-2 OR "micu 1" OR "micu 2" OR paracellin-1 OR claudin-16 OR pcln-1 OR claudin-19 OR mmgt1 OR mmgt2 OR alr1 OR alr2 OR mrs2 OR atmrs2 OR lpe10 ) filter any magnesium. enhanced from two tables of


18927203 The unique nature of mg2+ channels.
21640700 Cellular magnesium homeostasis. ---

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