Candidate Compounds Covid19

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  '''CHERRYPICKING STUDIES IS NOT SCIENCE
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{{qt|Reviews on covid drug development}}
  
current items will be put into the subsections.
 
  
*[[reviews on covid drug development]]
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*'''[[scouting ideas]]'''
*[[scouting ideas]]
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*[[Patients on biologicals]]
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*'''[[PHA Biologicals]]'''
*[[HMGB1, RAGE]]
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*[[pre-Interleukin 6]]
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*[[post-Interleukin 6]]
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*[[pre-TNFalpha]]
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*[[post-TNFalpha]]
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*[[pre-Interleukin 17]]
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*[[post-Interleukin 17]]
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*[[pre-Interleukin 1]]
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*[[post-Interleukin 1]]
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*[[Inflammasome]] ''colchicine''
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*[[Methotrexate]]
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*[[other anti-inflammatory]]
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*[[NK-kappaB]]
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*[[STAT 3]]
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*[[JAK Janus Kinase]]
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*[[Corticosteroids]]
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*[[Cytokine absorbers]]
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*[[Target Complement system]]
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*[[Target Extracellular traps]]
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*[[Target Neurophils]]
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*[[Target Mast cells]] and kinins
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*[[TGF beta]]
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*[[Immunosuppressants]]
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*[[Anticoagulant in covid19]]
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*[[Antioxidants]]
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*[[HIF-EPO-Iron]]
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*[[Stem cells]]
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*[[MDSC cells]]
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*[[Interferons]]
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*[[cAMP cGMP PDE NO]]
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*[[TRPV* channels]]
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*[[Retinoids]]
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*[[Protease inhibitors]]
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*[[Tyrosine kinase inhibitors]]
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*[[Antineoplastic agents, traditional]]
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*[[Mouthrinses]]
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*[[Adenosinergic signaling]]
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*[[Purinergic signaling]]
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*[[Nicotinergic signaling]]
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*'''[[PHA conventional pharmacology]]'''
  
*[[other single compounds]]
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*'''[[PHA retargeted compounds]]'''
*[[Retargeted Psychopharm]]
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*[[Hydroxychloroquine]]
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*
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*[[Target ACE2, Spike protein]]
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*[[Target TMPRSS2, Spike protein]] ''any other covid targed herein''
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*[[other antiviral compounds]]
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*[[AV Remdesivir]]
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*[[AV Lopinavir]]
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*[[AV Ivermectin]]
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*[[AV Arabidol]]
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*[[AV Favipiravir]]
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*[[Antibiotics]]
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*'''[[PHA antivirals by mechanism]]'''
  
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*'''[[PHA pharmacophore by screened target]]'''
  
*[[Vitamin D]]
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*'''[[PHA ImmunoNutrients]]
*[[Anorganic nutrients Magnesium]]
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*[[Anorganic nutrients Selenium]]
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*[[Anorganic nutrients Zinc]]
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*[[Anorganic nutrients Lithium]]
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*[[Anorganic nutrients Copper]]
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*[[Anorganic nutrients Bismuth]]
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*[[Nutrition, general]]
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*[[Exercise, Vibration]]
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*'''[[PHA compl altern natural]]'''
  
*[[Traditional Chinese Medicine]]
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*'''[[PHA within indications compounds]]'''
*[[Natural compounds]]
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*[[Statins]]
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*'''[[PHA Serum products]]'''
*[[Antidiabetic compounds, any]]
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*[[RSP - On RAS drugs]]
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*[[RSP - On NSAIDs]]
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*[[Reconvalescent blood products, Passive vaccine]]  
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*'''[[PHA Vaccination]]'''
*[[Plasmapheresis]]
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PHA related options:
  
*[[Immunodeviation]] e.g. by adjuvants or other vaccinations
 
 
*[[Radiation therapy]]
 
*[[Radiation therapy]]
 
*[[Phototherapy]]
 
*[[Phototherapy]]
*[[Active vaccine]]  
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*[[Electric fields]]
 
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*[[Treatment other concepts]]
 
*[[Treatment other concepts]]
----
 
  
{{tp|p=32417594|t=2020. Supplements for COVID-19: A modifiable environmental risk.|pdf=|usr=011}}
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A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
 +
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
 +
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
 +
Paper is (not yet in PubMed) :
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*'''[https://www.sciencedirect.com/science/article/pii/S1097276520305499?via%3Dihub Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication at Mol Cell 2020/08/11]'''
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credentials to [https://web.de/magazine/news/coronavirus/coronavirus-blockade-zellulaerer-kommunikation-forscher-stoppen-vermehrung-sars-cov-2-35045170 Marinus Brandl] who told us about it today.
 +
based on e.g.
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 +
{{ttp|p=32408336|t=2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets |pdf=|usr=}}
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=======================================================================================
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 +
COVID19 is now a CURABLE disease !!!
 +
 
 +
=======================================================================================

Aktuelle Version vom 21. September 2021, 06:15 Uhr

homepage
hottest actual papers
 P further streaming-in related content is here
 CHERRYPICKING STUDIES IS NOT SCIENCE
Reviews on covid drug development


PHA related options:


A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
Paper is (not yet in PubMed) :

credentials to Marinus Brandl who told us about it today. based on e.g.

32408336 2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
=======================================================================================
COVID19 is now a CURABLE disease !!!
=======================================================================================

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