PHA SCR nsp13 helicase, nucleotidase

PHA pharmacophore by screened target

living current stringent pubmed readout on nsp13 helicase

32500504 2020. SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts.
32875166 2020. In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors.
32980406 2020. Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13).
33052685 2020. Discovery of COVID-19 Inhibitors Targeting the SARS-CoV-2 Nsp13 Helicase.
31955138 2020. Design, synthesis and molecular docking of novel triazole derivatives as potential CoV helicase inhibitors.