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coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

Antibody-dependent enhancement


32361326 2020. Current studies of convalescent plasma therapy for COVID-19 may underestimate risk of antibody-dependent enhancement.

32504046 2020. Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures.
32092539 2020. Is COVID-19 receiving ADE from other coronaviruses?


32268188 ä. It is too soon to attribute ADE to COVID-19

31826992 2020. Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry
antibodies target one serotype of viruses but only subneutralize another, leading to antibody-dependend enhancement of the latter viruses.
32317716 ä. The potential danger of suboptimal antibody responses in COVID-19
ade


32346094 ä. COVID-19 vaccine design: the Janus face of immune enhancement
32303697 ä. Will we see protection or reinfection in COVID-19?
32438257 2020. SARS-CoV-2 and enhancing antibodies

32408068 2020. What about the original antigenic sin of the humans versus SARS-CoV-2?
the term «original antigenic sin» (OAS) was coined by T. Francis Jr at the Michigan University in the late 1950s to describe patterns of antibody response to influenza vaccination...


32436320 2020. The role of SARS-CoV-2 antibodies in COVID-19: Healing in most, harm at times.
32506725 2020. Dengue Fever, COVID-19 (SARS-CoV-2), and Antibody-Dependent Enhancement (ADE): A Perspective.
32529906 2020. Serological differentiation between COVID-19 and SARS infections.
32380903 2020. Lack of cross-neutralization by SARS patient sera towards SARS-CoV-2.
32426212 2020. Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections.
32526272 2020. Antibody-dependent enhancement and COVID-19: Moving toward acquittal.
32590062 2020. lall? Due diligence warranted for ADE in COVID-19.

32595955 2020. Expected immune recognition of COVID-19 virus by memory from earlier infections with common coronaviruses in a large part of the world population.


32582200 2020. Antibody Dependent Enhancement Due to Original Antigenic Sin and the Development of SARS.


Herd immunity


32438622 2020. Dynamics of Population Immunity Due to the Herd Effect in the COVID-19 Pandemic.
32391855 2020. COVID-19 and Postinfection Immunity: Limited Evidence, Many Remaining Questions.
32510562 2020. Long-term and herd immunity against SARS-CoV-2: implications from current and past knowledge.
32418947 2020. Does immune privilege result in recovered patients testing positive for COVID-19 again?
32372779 2020. Do you become immune once you have been infected?
32433946 2020. Herd Immunity: Understanding COVID-19.
32509257 2020. SARS-CoV-2, "common cold" coronaviruses' cross-reactivity and "herd immunity": The razor of Ockham (1285-1347)?
32397700 2020. [Analysis of application of herd immunity as a control strategy for COVID-19].
32534627 2020. Have deaths from COVID-19 in Europe plateaued due to herd immunity?
32434946 2020. SARS-CoV-2 infection protects against rechallenge in rhesus macaques.
32585285 2020. Herd Immunity and Vaccination of children for COVID19.
32576668 2020. A mathematical model reveals the influence of population heterogeneity on herd immunity to SARS-CoV-2.
32538831 2020. Herd immunity or suppression strategy to combat COVID-19.

Neutralizing antibodies


32454513 2020. Human neutralizing antibodies elicited by SARS-CoV-2 infection.
32454512 2020. A human neutralizing antibody targets the receptor binding site of SARS-CoV-2.
32497196 2020. Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients.

32073157 2020. Antibodies to coronaviruses are higher in older compared with younger adults and binding antibodies are more sensitive than neutralizing antibodies in identifying coronavirus?associated illnesses


32515685 2020. Dynamic surveillance of SARS-CoV-2 shedding and neutralizing antibody in children with COVID-19.
32514035 2020. Dissecting antibody-mediated protection against SARS-CoV-2.
32561270 2020. Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation.


Innate immunology

32291557 ä. SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells


32198201 2020. Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors
32374430 2020. DC/L-SIGNs of Hope in the COVID-19 Pandemic
32361001 ä. Bioinformatic analysis and identification of single-stranded RNA sequences recognized by TLR7/8 in the SARS-CoV-2, SARS-CoV, and MERS-CoV genomes
32248387 ä. Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution

32407669 ä. Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients


32456409 2020. A theory on SARS-COV-2 susceptibility: reduced TLR7-activity as a mechanistic link between men, obese and elderly.

32156572 2020. Viroporins and inflammasomes: A key to understand virus-induced inflammation
32454408 2020. COVID-19 as a STING disorder with delayed over-secretion of interferon-beta.


32524333 2020. COVID 19: a clue from innate immunity.
32464098 2020. The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?

32599245 2020. Targeting hub genes and pathways of innate immune response in COVID-19: A network biology perspective.
32574272 2020. Innate Immune Signaling and Proteolytic Pathways in the Resolution or Exacerbation of SARS-CoV-2 in Covid-19: Key Therapeutic Targets?


integrative work


32205856 2020. COVID-19 infection: the perspectives on immune responses
32359396 ä. A Dynamic Immune Response Shapes COVID-19 Progression
C7064018 ä. Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

C7200337 ä. Immunology of COVID-19: current state of the science


32505227 2020. Immunology of COVID-19: Current State of the Science.
32469225 2020. COVID-19 and the immune system.

32436629 2020. High COVID-19 virus replication rates, the creation of antigen-antibody immune complexes and indirect haemagglutination resulting in thrombosis.


32507543 2020. Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2.

32504757 2020. Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications.


32493812 2020. Role of Aging and the Immune Response to Respiratory Viral Infections: Potential Implications for COVID-19.
32470151 2020. The perplexing question of trained immunity versus adaptive memory in COVID-19.
32472706 2020. The Long-Standing History of Corynebacterium Parvum, Immunity and Viruses.
32213336 ä. SARS-CoV-2: virus dynamics and host response
32437933 2020. Viral dynamics in asymptomatic patients with COVID-19.
32407836 2020. Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China.
32498686 2020. Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19).
32514817 2020. Immune Responses to SARS-CoV, MERS-CoV and SARS-CoV-2.
32460144 2020. Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions.
32417709 2020. Mechanism of inflammatory response in associated comorbidities in COVID-19.
32444400 2020. COVID-19 and the nicotinic cholinergic system.
32413330 2020. Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.
32514174 2020. A single-cell atlas of the peripheral immune response in patients with severe COVID-19.
32489708 2020. Immune Characteristics of Patients with Coronavirus Disease 2019 (COVID-19).
32396996 2020. Immune response to SARS-CoV-2 and mechanisms of immunopathological changes in COVID-19.

32454136 2020. The role of IgA in COVID-19.
32526273 2020. A plea for the pathogenic role of immune complexes in severe Covid-19.


32502542 2020. The immune system and COVID-19: Friend or foe?
32505066 2020. COVID-19: Loss of bridging between innate and adaptive immunity?
32461671 2020. Innate T cells in COVID-19: friend or foe?
32533292 2020. Targeting the immunology of coronavirus disease-19: synchronization creates symphony.
32445403 2020. SARS-CoV-2 infection-induced immune responses: Friends or foes?
32510470 2020. Is innate immunity our best weapon for flattening the curve?
32574709 2020. COVID-19 pneumonia: CD8(+) T and NK cells are decreased in number but compensatory increased in cytotoxic potential.
32578831 2020. Human Leukocyte Transcriptional Response to SARS-CoV-2 Infection.
32584441 2020. Immunology of COVID-19: mechanisms, clinical outcome, diagnostics and perspectives - a report of the European Academy of Allergy and Clinical Immunology (EAACI).
32592406 2020. Immune response in children with COVID-19 is characterized by lower levels of T cell activation than infected adults.

32579268 2020. SARS-CoV-2-reactive interferon-gamma-producing CD8+ T cells in patients hospitalized with coronavirus disease 2019.


32591408 2020. Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome.
32576386 2020. Deciphering the TCR Repertoire to Solve the COVID-19 Mystery.
32582743 2020. Immune-Inflammatory Parameters in COVID-19 Cases: A Systematic Review and Meta-Analysis.


covid modulates the immune system

32514047 2020. Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19).
32479746 2020. Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients.
32529952 2020. SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists.


32364527 2020. Immune environment modulation in pneumonia patients caused by coronavirus: SARS-CoV, MERS-CoV and SARS-CoV-2
32172672 2020. A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses
32315725 ä. Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan, China

32355328 ä. Impaired interferon signature in severe COVID-19


32375560 2020. SARS-CoV-2-Induced Immune Dysregulation and Myocardial Injury Risk in China: Insights from the ERS-COVID-19 Study
32376308 ä. Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis

32236983 2020. Why the immune system fails to mount an adaptive immune response to a COVID-19 infection
32286536 ä. Coronaviruses hijack the complement system
host complement activator MASP2 as a target of the N protein of all three viruses


32463803 2020. Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent.
32492165 2020. Clinical and Immune Features of Hospitalized Pediatric Patients With Coronavirus Disease 2019 (COVID-19) in Wuhan, China.
32514592 2020. Severe COVID-19 is associated with deep and sustained multifaceted cellular immunosuppression.
32456696 2020. COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients.
32502135 2020. Reduced monocytic HLA-DR expression indicates immunosuppression in critically ill COVID-19 patients.
32532524 2020. SARS-CoV-2-A Tough Opponent for the Immune System.
32416070 2020. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
32513989 2020. The inhibition of IL-2/IL-2R gives rise to CD8(+) T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia.
32409741 2020. Modulation of immune crosstalk in COVID-19.
32504059 2020. Many paths to COVID-19 lymphocyte dysfunction.
32528136 2020. Considering how biological sex impacts immune responses and COVID-19 outcomes.
32587367 2020. Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients.
32554697 2020. Inactivating Three Interferon Antagonists Attenuates Pathogenesis of an Enteric Coronavirus.


immune cell subpopulations


32282871 ä. Inflammatory Response Cells During Acute Respiratory Distress Syndrome in Patients With Coronavirus Disease 2019 (COVID-19)
32325421 2020. Increased expression of CD8 marker on T-cells in COVID-19 patients
32377375 2020. Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing
32346099 ä. High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients
32339487 2020. Abnormalities of peripheral blood system in patients with COVID-19 in Wenzhou, China
32361250 2020. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients
32228226 2020. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
32196410 2020. Hypothesis for potential pathogenesis of SARS-CoV-2 infection?a review of immune changes in patients with viral pneumonia
32333914 ä. A possible role for B cells in COVID-19?: Lesson from patients with Agammaglobulinemia
32344320 ä. The clinical course and its correlated immune status in COVID-19 pneumonia
32325129 ä. The profile of peripheral blood lymphocyte subsets and serum cytokines in children with 2019 novel coronavirus pneumonia
32283159 ä. Lymphocyte subset (CD4+, CD8+) counts reflect the severity of infection and predict the clinical outcomes in patients with COVID-19
32227123 ä. Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia
32343510 2020. COVID-19: are T lymphocytes simply watching?
32379887 ä. T cell subset counts in peripheral blood can be used as discriminatory biomarkers for diagnosis and severity prediction of COVID-19
32297671 2020. Relationships among lymphocyte subsets, cytokines, and the pulmonary inflammation index in coronavirus (COVID-19) infected patients
32352397 2020. The hemocyte counts as a potential biomarker for predicting disease progression in COVID-19: a retrospective study
32379199 2020. A Typical Case of Critically Ill Infant of Coronavirus Disease 2019 With Persistent Reduction of T Lymphocytes
32296069 2020. Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study
32407057 2020. Peripheral lymphocyte subset monitoring in COVID19 patients: a prospective Italian real-life case series.
32297828 2020. Correlation Between Relative Nasopharyngeal Virus RNA Load and Lymphocyte Count Disease Severity in Patients with COVID-19
32370466 2020. Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19
32114745 2020. Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19
32377375 2020. Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing
32361250 2020. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

32376308 2020. Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis


32458561 2020. Lymphopenia in COVID-19: Therapeutic opportunities.
32420610 2020. Temporal changes in immune blood cell parameters in COVID-19 infection and recovery from severe infection.
32470153 2020. Characteristics of inflammatory factors and lymphocyte subsets in patients with severe COVID-19.
32474608 2020. Decreased B cells on admission was associated with prolonged viral RNA shedding from respiratory tract in Coronavirus Disease 2019: a case control study.
32483488 2020. Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis.
32382776 2020. Signals of Th2 immune response from COVID-19 patients requiring intensive care.
32417210 2020. The underlying changes and predicting role of peripheral blood inflammatory cells in severe COVID-19 patients: A sentinel?
32405080 2020. Decreased T cell populations contribute to the increased severity of COVID-19.
32407466 2020. An inflammatory profile correlates with decreased frequency of cytotoxic cells in COVID-19.
32569607 2020. Lymphopenia during the COVID-19 infection: What it shows and what can be learned.
32543971 2020. Increased CD4/CD8 ratio as a risk factor for critical illness in coronavirus disease 2019 (COVID-19): a retrospective multicentre study.
32598880 2020. Less expression of CD4(+) and CD8(+) T cells might reflect the severity of infection and predict worse prognosis in patients with COVID-19: Evidence from a pooled analysis.
32569604 2020. CD4+T, CD8+T counts and severe COVID-19: A meta-analysis.
32608572 2020. Peripheral lymphocyte subset alterations in COVID-19 patients.


t cell exhaustion


32249845 ä. Fighting COVID-19 exhausts T cells
32479985 2020. Selective CD8 cell reduction by SARS-CoV-2 is associated with a worse prognosis and systemic inflammation in COVID-19 patients.

32203188 ä. Functional exhaustion of antiviral lymphocytes in COVID-19 patients
32203186 ä. Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients
32203188 2020. Functional exhaustion of antiviral lymphocytes in COVID-19 patients
32203186 2020. Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients


32414395 2020. COVID-19: room for treating T cell exhaustion?
32425950 2020. Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19).
32539816 2020. Response to "COVID-19: room for treating T cell exhaustion?"


nk cells


32382127 ä. NKG2A and COVID-19: another brick in the wall
32344314 2020. Innate immunity in COVID-19 patients mediated by NKG2A receptors, and potential treatment using Monalizumab, Cholroquine, and antiviral agents


plasmacytoid dendritic cells


32298486 2020. Plasmacytoid lymphocytes in SARS-CoV-2 infection (Covid-19)


antiviral immune response


32280952 ä. Good IgA bad IgG in SARS-CoV-2 infection?
32353870 2020. The many faces of the anti-COVID immune response
32358956 ä. Longitudinal Change of SARS-Cov2 Antibodies in Patients with COVID-19
31981224 2020. Coronavirus infections and immune responses
32198005 2020. A case of COVID-19 and pneumonia returning from Macau in Taiwan: Clinical course and anti-SARS-CoV-2 IgG dynamic
32284614 ä. Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
32355329 ä. SARS-CoV-2-reactive T cells in patients and healthy donors
32346091 ä. Neutralizing antibody response in mild COVID-19
32356908 2020. Mathematical modeling of interaction between innate and adaptive immune responses in COVID-19 and implications for viral pathogenesis

32343415 2020. Long-term coexistence of SARS-CoV-2 with antibody response in COVID-19 patients


32330332 2020. SARS-CoV-2 infection in children - Understanding the immune responses and controlling the pandemic
32267987 2020. Immune responses and pathogenesis of SARS?CoV?2 during an outbreak in Iran: Comparison with SARS and MERS
32348715 2020. B Cells, Viruses, and the SARS-CoV-2/COVID-19 Pandemic of 2020
32382126 ä. Protective humoral immunity in SARS-CoV-2 infected pediatric patients
32200654 2020. Time Kinetics of Viral Clearance and Resolution of Symptoms in Novel Coronavirus Infection
32476607 2020. Delayed specific IgM antibody responses observed among COVID-19 patients with severe progression.
32449333 2020. (+)Ability of the immune system to fight viruses highlighted by cytometry and TCR clonotype assessments: lessons taken prior to COVID-19 virus pandemic outbreak.
32430094 2020. The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection.
32467617 2020. Serum IgA, IgM, and IgG responses in COVID-19.

32467616 2020. More bricks in the wall against SARS-CoV-2 infection: involvement of gamma9delta2 T cells.
32463434 2020. Metatranscriptomic Characterization of COVID-19 Identified A Host Transcriptional Classifier Associated With Immune Signaling.


32398307 2020. Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients.
32425634 2020. The dynamics of antibodies to SARS-CoV-2 in a case of SARS-CoV-2 infection.
32383183 2020. A comparison study of SARS-CoV-2 IgG antibody between male and female COVID-19 patients: A possible reason underlying different outcome between sex.
32521002 2020. Antibody profiles in mild and severe cases of COVID-19.
32399213 2020. Dynamics of peripheral immune cells and their HLA-G and receptor expressions in a patient suffering from critical COVID-19 pneumonia to convalescence.
32515684 2020. Patterns of IgG and IgM antibody response in COVID-19 patients.

32425955 2020. Potential SARS-CoV-2 Preimmune IgM Epitopes.


32439770 2020. T cells found in coronavirus patients 'bode well' for long-term immunity.

32473127 2020. Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.


32513850 2020. Early Insights into Immune Responses during COVID-19.
32544611 2020. Development of child immunity in the context of COVID-19 pandemic.
32572527 2020. SARS-CoV-2 viral loads and serum IgA/IgG immune responses in critically ill COVID-19 patients.
32607314 2020. Assessing Immune Response to SARS-CoV-2 Infection.
32574261 2020. Humoral Immune Responses in COVID-19 Patients: A Window on the State of the Art.


antiviral mediators


32422144 2020. Perforin and resistance to SARS coronavirus 2.

32437749 2020. Human Intestinal Defensin 5 Inhibits SARS-CoV-2 Invasion by Cloaking ACE2.


mediators


32360285 ä. Type I IFN immunoprofiling in COVID-19 patients

32376393 ä. Interleukin-17A (IL-17A), a key molecule of innate and adaptive immunity, and its potential involvement in COVID-19-related thrombotic and vascular mechanisms
32305501 ä. The Potential Role of Th17 Immune Responses in Coronavirus Immunopathology and Vaccine-induced Immune Enhancement


30715745 2019. (+)Th17 serum cytokines in relation to laboratory?confirmed respiratory viral infection: A pilot study
32414693 2020. Interleukin-6 levels in children developing SARS-CoV-2 infection

32421281 2020. Is there relationship between SARS-CoV 2 and the complement C3 and C4?


32437622 2020. Complement Activation During Critical Illness: Current Findings and an Outlook in the Era of COVID-19.
32475759 2020. IL-6: Relevance for immunopathology of SARS-CoV-2.
32457522 2020. Dysregulation of type I interferon responses in COVID-19.
32435059 2020. A suspicious role of interferon in the pathogenesis of SARS-CoV-2 by enhancing expression of ACE2.
32464309 2020. Type I interferons can be detected in respiratory swabs from SARS-Cov-2 infected patients.
32553163 2020. Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins.
32579952 2020. Hyperferritinemia in critically ill COVID-19 patients - Is ferritin the product of inflammation or a pathogenic mediator?
32540458 2020. Elevated nucleoprotein-induced interferon-gamma release in COVID-19 patients detected in a SARS-CoV-2 enzyme-linked immunosorbent spot assay.
32563194 2020. Serum Cytokine and Chemokine profile in Relation to the Severity of Coronavirus disease 2019 (COVID-19) in China.

32595654 2020. Interferon-Induced Transmembrane Protein (IFITM3) Is Upregulated Explicitly in SARS-CoV-2 Infected Lung Epithelial Cells.


32574271 2020. The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria.


immunopathology


32371101 ä. The correlation between SARS-CoV-2 infection and rheumatic disease
32205186 2020. COVID-19 infection and rheumatoid arthritis: Faraway, so close!
32308263 2020. CoViD-19 Immunopathology and Immunotherapy
32320677 ä. Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
32161940 ä. Dysregulation of immune response in patients with COVID-19 in Wuhan, China
32282863 ä. Molecular immune pathogenesis and diagnosis of COVID-19
32321823 2020. COVID-19: an Immunopathological View
32273594 ä. COVID-19: immunopathology and its implications for therapy
32303696 ä. Macrophages: a Trojan horse in COVID-19?

32376901 ä. Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages


32423059 2020. Recent Insight into SARS-CoV2 Immunopathology and Rationale for Potential Treatment and Preventive Strategies in COVID-19.
32485101 2020. Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak.
32423917 2020. COVID-19 as an Acute Inflammatory Disease.

32512289 2020. Neutralizing antibodies mediate virus-immune pathology of COVID-19.


32398875 2020. Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19.
32391668 2020. [Dynamic inflammatory response in a critically ill COVID-19 patient treated with corticosteroids].

32498376 2020. Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19.


32460357 2020. Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China.

32492530 2020. Aberrant hyperactivation of cytotoxic T-cell as a potential determinant of COVID-19 severity.


32389590 2020. COVID-19: Unanswered questions on immune response and pathogenesis.
32422146 2020. Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells.
32521376 2020. SARS-CoV-2 (Covid-19): Interferon-epsilon may be responsible of decreased mortality in females.
32470851 2020. Role of oxidized LDL-induced "trained macrophages" in the pathogenesis of COVID-19 and benefits of pioglitazone: A hypothesis.
32454103 2020. Type I astrocytes and microglia induce a cytokine response in an encephalitic murine coronavirus infection.
32398804 2020. Is aberrant CD8+ T cell activation by hypertension associated with cardiac injury in severe cases of COVID-19?
32466999 2020. COVID-19 and asthma: To have or not to have T2 inflammation makes a difference?
32581077 2020. COVID-19 Hyperinflammation: What about Neutrophils?
32582303 2020. Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study.
32543740 2020. Dysregulation of the immune response affects the outcome of critical COVID-19 patients.
32573711 2020. Platelet Gene Expression and Function in COVID-19 Patients.
32579477 2020. Platelets and Immunity: Going Viral.
32545714 2020. Reaction Cycles of Halogen Species in the Immune Defense: Implications for Human Health and Diseases and the Pathology and Treatment of COVID-19.
32591762 2020. COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis.
32584597 2020. Characterization of the Inflammatory Response to Severe COVID-19 Illness.
32574260 2020. Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection.

secondary autoimmunity


32292901 2020. Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity
32220633 2020. Could Sars-coronavirus-2 trigger autoimmune and/or autoinflammatory mechanisms in genetically predisposed subjects?
32315487 2020. Clinical and Autoimmune Characteristics of Severe and Critical Cases of COVID-19

32314313 2020. Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena?


32389543 ä. COVID-19 and molecular mimicry: The Columbus? egg?
32444414 2020. Antibodies against immunogenic epitopes with high sequence identity to SARS-CoV-2 in patients with autoimmune dermatomyositis.

32535095 2020. Molecular mimicry may explain multi-organ damage in COVID-19.


32535093 2020. Covid-19 and autoimmunity.
32461193 2020. Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases.
32504061 2020. SARS-CoV-2 cross-reactivity in healthy donors.
32387238 2020. Covid-19, induced activation of hemostasis, and immune reactions: Can an auto-immune reaction contribute to the delayed severe complications observed in some patients?
32563547 2020. Autoinflammatory and autoimmune conditions at the crossroad of COVID-19.


Thymus


32340873 ä. Reply: Thymopoiesis, inflamm-aging, and COVID-19 phenotype
32317217 ä. Role of thymopoiesis and inflamm-aging in COVID-19 phenotype


Eosinopenia, Eosinophilia


32368728 ä. Eosinopenia and elevated C-reactive protein facilitate triage of COVID-19 patients in fever clinic: a retrospective case-control study
32344056 ä. Eosinophil Responses During COVID-19 Infections and Coronavirus Vaccination
32369190 2020. COVID-19, chronic inflammatory respiratory diseases and eosinophils - Observationsfrom reported clinical case series

32315429 ä. Eosinophil count in severe coronavirus disease 2019 (COVID-19)


32315421 ä. Response letter to Eosinophil count in severe coronavirus disease 2019 (COVID-19)
32390402 2020. SARS-CoV-2 and Eosinophilia.
32544911 2020. Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection.
32540792 2020. Eosinophil Response Against Classical and Emerging Respiratory Viruses: COVID-19.
32572245 2020. Roles for eosinophils and basophils in COVID-19?

Immunosenescence


32597792 2020. Reversing immunosenescence for prevention of COVID-19.
32583231 2020. Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity.
32556942 2020. Severe COVID-19 and aging: are monocytes the key?
32544216 2020. COVID-19 and Crosstalk With the Hallmarks of Aging.
32489698 2020. COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile.


microbiome


32497191 2020. Alterations of the Gut Microbiota in Patients with COVID-19 or H1N1 Influenza.

32426999 2020. Gnotobiotic Rats Reveal That Gut Microbiota Regulates Colonic mRNA of Ace2, the Receptor for SARS-CoV-2 Infectivity.


32432790 2020. Editorial - COVID-19 and the microbiota: new kids on the block.
32442562 2020. Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization.

32579014 2020. Systemic inflammatory response and thrombosis due to alterations in the gut microbiota in COVID-19.


32552848 2020. Compassionate use of others' immunity - understanding gut microbiome in Covid-19.
32582138 2020. Intestinal Flora as a Potential Strategy to Fight SARS-CoV-2 Infection.
32582134 2020. Main Clinical Features of COVID-19 and Potential Prognostic and Therapeutic Value of the Microbiota in SARS-CoV-2 Infections.
32574708 2020. Mitochondria and Microbiota dysfunction in COVID-19 pathogenesis.
32579301 2020. Immunity and protection from COVID-19-Environmental mycobacteria play a role.

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