Pathobiology
coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.
32273135 ä. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases
32275742 ä. COVID-19 Autopsies, Oklahoma, USA
32361635 2020. Analysis of complement deposition and viral RNA in placentas of COVID-19 patients
32163542 ä. Histopathologic Changes and SARS?CoV-2 Immunostaining in the Lung of a Patient With COVID-19
32360606 2020. SARS-CoV2 entry and spread in the lymphatic drainage system of the brain
32353523 ä. SARS-CoV-2: a new virus but a familiar inflammation brain pattern
32370257 2020. Bioenergy Crisis in Coronavirus Diseases?
32375085 ä. Pathophysiological Characteristics and Therapeutic Approaches for Pulmonary Injury and Cardiovascular Complications of Coronavirus Disease 2019
32346074 ä. Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient
32360729 ä. Postmortem Lung Findings in an Asthmatic with Coronavirus Disease 2019 (COVID-19)
32283063 ä. A call to action : the need for autopsies to determine the full extent of organ involvement associated with COVID-19 infections
32334082 ä. ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection
32270184 ä. Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19
32307550 ä. Down-regulated gene expression spectrum and immune responses changed during the disease progression in COVID-19 patients
32207983 2020. Covid-19 infection and mortality: a physiologist?s perspective enlightening clinical features and plausible interventional strategies
32234451 ä. COVID-19, SARS and MERS: are they closely related?
32294179 ä. Coronavirus infections and type 2 diabetes-shared pathways with therapeutic implications
32293672 ä. Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts
32350105 ä. Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection
32341103 2020. Understanding the Renin-Angiotensin-Aldosterone-SARS-CoV-Axis: A Comprehensive Review
32198987 2020. Gross examination report of a COVID-19 death autopsy
32198986 2020. Review and Prospect of Pathological Features of Corona Virus Disease
32198985 2020. Guide to the Forensic Pathology Practice on Death Cases Related to Corona Virus Disease 2019 COVID-19 Trial Draft
32198984 2020. Academician Cong Bin: Autopsy of SARS-CoV-2 infection is needed to be strengthened
32198983 2020. From SARS-CoV to SARS-CoV-2: The response and challenge of forensic infectious disease autopsy
32170560 ä. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
32317509 2020. COVID-19 and lung pathology
32345362 2020. Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues
32333601 ä. Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD
32094336 2020. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
32283245 ä. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated
32282428 ä. What s Old is New! Similarities Between SARS-CoV-2 and HIV
32303424 ä. Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19
32315733 ä. Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms
32357503 2020. COVID-19 Deaths: Are We Sure It Is Pneumonia? Please, Autopsy, Autopsy, Autopsy!
32244779 2020. Master Regulator Analysis of the SARS-CoV-2/Human Interactome
32366599 2020. SARS-CoV-2 detection in formalin-fixed paraffin-embedded tissue specimens from surgical resection of tongue squamous cell carcinoma
32283163 ä. A potential inhibitory role for integrin in the receptor targeting of SARS-CoV-2
32348495 ä. Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with disease severity in COVID-19
32344401 2020. COVID-19: Possible Impact of the Genetic Background in IFNL Genes on Disease Outcomes
32080991 2020. Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea
32056249 2020. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS?CoV, MERS?CoV, and 2019?nCoV
32340678 2020. Pathology of 2019 Novel Coronavirus Pneumonia: A Dynamic Disease Process
32194247 ä. Exuberant Plasmocytosis in Bronchoalveolar Lavage Specimen of the First Patient Requiring Extracorporeal Membrane Oxygenation for SARS-CoV-2 in Europe
32114094 ä. Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer
32379723 2020. Molecular detection of SARS-CoV-2 in formalin fixed paraffin embedded specimens
| 32329756 2020. Neutrophil extracellular traps in COVID-19 |
32368701 ä. COVID-19?Associated Collapsing Glomerulopathy: An Emerging Entity
32327202 ä. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China
C7142700 ä. Collapsing Glomerulopathy in a Patient With Coronavirus Disease 2019 (COVID-19)
32346659 ä. Acute Kidney Injury Due to Collapsing Glomerulopathy Following COVID-19 Infection
32311318 ä. SARS-CoV-2 and viral sepsis: observations and hypotheses
32325026 2020. Endothelial cell infection and endotheliitis in COVID-19
32199493 ä. Viral dynamics in mild and severe cases of COVID-19
32330440 ä. Mediastinal lymphadenopathy in patients with severe COVID-19
32105638 ä. Viral load of SARS-CoV-2 in clinical samples
32085846 ä. Pathological findings of COVID-19 associated with acute respiratory distress syndrome
32341791 2020. Thoughts on COVID-19 and autoimmune diseases
32344305 ä. A data-driven hypothesis on the epigenetic dysregulation of host metabolism by SARS coronaviral infection: potential implications for the SARS-CoV-2 modus operandi
32243911 ä. C-reactive protein levels in the early stage of COVID-19
32291399 ä. Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies
32249846 ä. Dysregulation of lung myeloid cells in COVID-19
32216698 2020. Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility
32297540 2020. Association between platelet parameters and mortality in coronavirus disease 2019: Retrospective cohort study
32348339 2020. Correlation between Heart fatty acid binding protein and severe COVID-19: A case-control study
32298273 2020. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study
32326988 ä. Lactose Dehydrogenase in Patients with Severe COVID-19: A Meta-Analysis of Retrospective Study
32339247 ä. Does apolipoprotein E genotype predict COVID-19 severity?
32371949 2020. Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study
| 32360977 ä. The role of Neutrophil Extracellular Traps in Covid-19: Only an hypothesis or a potential new field of research? |
| 32305740 ä. Severe COVID-19 infection associated with endothelial activation |
| 32299776 ä. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases |
32283217 ä. Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings
32356025 ä. Early histologic findings of pulmonary SARS-CoV-2 infection detected in a surgical specimen
32350596 ä. The autopsy debate during the COVID-19 emergency: the Italian experience
32379417 ä. Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age
| 32376402 ä. Transcriptional landscape of SARS-CoV-2 infection dismantles pathogenic pathways activated by the virus, proposes unique sex-specific differences and predicts tailored therapeutic strategies |
| 32361194 ä. Molecular mimicry between SARS-CoV-2 and respiratory pacemaker neurons |
| 32323565 2020. Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19? |
32379894 2020. Association between ABO blood groups and risk of SARS-CoV-2 pneumonia
32259373 2020. Cytologic and histologic samples from patients infected by the novel coronavirus 2019 SARS-CoV-2: An Italian institutional experience focusing on biosafety procedures
32346073 2020. COVID-19: towards understanding of pathogenesis
32294809 2020. Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis
32246845 2020. SARS?CoV?2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells
32353898 2020. Histopathology and genetic susceptibility in COVID-19 pneumonia
32367579 2020. The lysosome: A potential juncture between SARS-CoV-2 infectivity and Niemann-Pick disease type C, with therapeutic implications
32364407 2020. COVID-19 Lung Injury Is Different From High Altitude Pulmonary Edema (Re: High Alt Med Biol Epub ahead of print ; DOI: 10 1089/ham 2020 0055)
32281877 2020. COVID-19 Lung Injury is Not High Altitude Pulmonary Edema
32374419 2020. Pulmonary Pathology of Early Phase COVID-19 Pneumonia in a Patient with a Benign Lung Lesion
| 32364264 2020. Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction |
| 32371536 2020. Ultrastructural Evidence for Direct Renal Infection with SARS-CoV-2 |
32198191 2020. Autopsy in suspected COVID-19 cases
32358895 2020. Histological pattern in Covid-19 induced viral rash
32369204 2020. Hepatic involvement in COVID-19 patients: Pathology, pathogenesis, and clinical implications
32294295 2020. Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19
| 32376101 ä. Association Between Hypoxemia and Mortality in Patients With COVID-19 |
| 32272081 2020. Understanding pathways to death in patients with COVID-19 |
32327758 2020. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
32273618 2020. How does COVID-19 kill? Uncertainty is hampering doctors ability to choose treatments
| 32371892 2020. COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms |
32339089 2020. Issues on Coronavirus Disease 2019 (COVID-19) Pathogenesis
32172546 2020. A pathological report of three COVID-19 cases by minimal invasive autopsies
32171194 2020. Pathological changes with novel coronavirus infection in lung cancer surgical specimen
32153166 2020. Provisional guidelines on autopsy practice for deaths associated with COVID-19
32268662 2020. Analysis of coronavirus disease-19 (COVID-19) based on SARS autopsy
32157847 2020. How to understand the histopathology of SARS and coronavirus disease-19 (COVID-19) associated with acute respiratory distress syndrome
32084674 2020. Detection of 2019-nCoV in the pathological paraffin embedded tissue
32340089 2020. Pathological changes of the spleen in ten patients with new coronavirus infection by minimally invasive autopsies
32114744 2020. Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases
32174095 2020. Advances in the research of mechanism of pulmonary fibrosis induced by Corona Virus Disease 2019 and the corresponding therapeutic measures
C7173822 2020. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study
32379077 2020. COVID-19: POSTMORTEM DIAGNOSTIC AND BIOSAFETY CONSIDERATIONS
32434133 2020. The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): Report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities
| 32314313 ä. Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena? |
32427582 2020. Clinical and pathological investigation of severe COVID-19 patients.
| 32512569 2020. COVID-19 Attacks the Kidney: Ultrastructural Evidence for the Presence of Virus in the Glomerular Epithelium. |
| 32403217 2020. Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence. |
32272221 ä. Host proteases as determinants of coronaviral neurotropism and virulence
| 32243808 2020. The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future |
32375845 2020. Acute respiratory failure in COVID-19: is it ?typical? ARDS?
32439197 ä. COVID-19 and Multiorgan Response
32362921 2020. Hypoxia in acute cardiac injury of coronavirus disease 2019: lesson learned from pathological studies
32340677 2020. Pulmonary Pathology of Early Phase 2019 Novel Coronavirus Pneumonia
32471641 ä. Tubuloreticular inclusions in COVID-19?related collapsing glomerulopathy
32471639 ä. Collapsing glomerulopathy in a COVID-19 patient
32292867 2020. Collapsing Glomerulopathy in a Patient With COVID-19
32459663 2020. COVID-19, microangiopathy, hemostatic activation, and complement.
32242089 ä. Endocrine and metabolic link to coronavirus infection
32382135 ä. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis
C7158196 2009. 64pp on topic review (+) Molecular Basis of Pulmonary Disease
C7197563 ä. Plasma Metabolomic and Lipidomic Alterations Associated with COVID-19
32454497 2020. COVID-19 and Nasal Cytobrush Cytology.
32437316 2020. Pathology and Pathogenesis of SARS-CoV-2 Associated with Fatal Coronavirus Disease, United States.
32412897 2020. Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan.
32484232 2020. Radiologisk och histologisk bild for en okad forstaelse vid covid-19.
32512290 2020. Expression of angiotensin-converting enzyme 2 and proteases in COVID-19 patients: A potential role of cellular FURIN in the pathogenesis of SARS-CoV-2.
| 32401000 2020. First ultrastructural autoptic findings of SARS-Cov-2 in olfactory pathways and brainstem. |
32397896 2020. Placental Pathology in Covid-19 Positive Mothers: Preliminary Findings.
| 32436629 2020. High COVID-19 virus replication rates, the creation of antigen-antibody immune complexes and indirect haemagglutination resulting in thrombosis. |
| 32421281 2020. Is there relationship between SARS-CoV 2 and the complement C3 and C4? |
32485101 2020. Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak.
32423917 2020. COVID-19 as an Acute Inflammatory Disease.
32469258 2020. Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients.
| 32437597 2020. Covid-19, Angiogenesis, and ARDS Endotypes. |
| 32437596 2020. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. |
32213267 2020. [Interpretation of pathological changes for "Guidelines for the Diagnosis and Treatment of COVID-19 by the National Health Commission (Trial Version 7) "].
| 32490726 2020. Thromboinflammatory response in SARS-CoV-2 sepsis. |
| 32348061 2020. COVID-19, une maladie endotheliale ? |
32455515 2020. [Clinical feature changes of a COVID-19 patient from mild to critical condition and cardiopulmonary pathological results].
| 32498376 2020. Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19. |
32486534 2020. [Pathological changes of fatal coronavirus disease 2019 (COVID-19) in the lungs: report of 10 cases by postmortem needle autopsy].
32433216 2020. Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Corona virus.
| 32452762 2020. SARS-CoV-2 strategically mimics proteolytic activation of human ENaC. |
32507410 2020. The influenza virus, SARS-CoV-2, and the airways: Clarification for the otorhinolaryngologist.
32508022 2020. Acute lung injury in patients with COVID-19 infection.
32490934 2020. Ultrasound-guided minimally invasive autopsies: A protocol for the study of pulmonary and systemic involvement of COVID-19.
32443177 2020. Pulmonary and systemic involvement of COVID-19 assessed by ultrasound-guided minimally invasive autopsy.
| 32441844 2020. Involvement of ADAMTS13 and von Willebrand factor in thromboembolic events in patients infected with SARS-CoV-2. |
| 32397951 2020. The expression level of angiotensin-converting enzyme 2 determines the severity of COVID-19: lung and heart tissue as targets. |
| 32420587 2020. COVID-19 as a cardiovascular disease: the potential role of chronic endothelial dysfunction. |
| 32479682 2020. Preeclampsia-like syndrome induced by severe COVID-19: a prospective observational study. |
| 32497257 2020. A lesson from a saboteur: high molecular weight kininogen (HMWK) impact in COVID-19. |
32488957 2020. Procedures for Flow Cytometry-Based Sorting of Unfixed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Cells and Other Infectious Agents.
32468052 2020. Pancancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARSCoV2 infection leading to COVID-19.
| 32510973 2020. Decoding SARS-CoV-2 Hijacking of Host Mitochondria in Pathogenesis of COVID-19. |
| 32497323 2020. Increasing Host Cellular Receptor-Angiotensin-Converting Enzyme 2 (ACE2) Expression by Coronavirus may Facilitate 2019-nCoV (or SARS-CoV-2) Infection. |
| 32469255 2020. SARS-CoV-2 perturbs the Renin-Angiotensin System and energy metabolism. |
| 32492203 2020. Structural variations and expression profiles of the SARS-CoV-2 host invasion genes in Lung cancer. |
| 32434769 2020. Viropathic multinuclear syncytial giant cells in bronchial fluid from a patient with COVID-19. |
| 32501731 2020. Cholesterol: A new game player accelerating endothelial injuries caused by SARS-CoV-2? |
32506059 2020. Detection of Hemosiderin-Laden Macrophages in Bronchoalveolar Lavage Fluid of COVID-19 Patients: Is Perls Stain a Potential Indicator of Oxidative Alveolar Damage?
| 32496587 2020. Distribution of ACE2, CD147, CD26 and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors. |
32432483 2020. Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium.
32437622 2020. Complement Activation During Critical Illness: Current Findings and an Outlook in the Era of COVID-19.
32472588 2020. Increased sFLT1/PlGF ratio in COVID-19: a novel link to Angiotensin II-mediated endothelial dysfunction.
32491212 2020. Circulating endothelial cells in COVID-19.
32479159 2020. Related molecular mechanisms of COVID-19, hypertension, and diabetes.
32510978 2020. Overcoming Barriers: The Endothelium As a Linchpin of Coronavirus Disease 2019 Pathogenesis?
32441303 2020. Placental Pathology in COVID-19.
32451533 2020. Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases.
32420938 2020. What happens to people's lungs when they get coronavirus disease 2019?
32493030 2020. Thoughts on the alveolar phase of COVID-19.
| 32444466 2020. The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2. |
32422081 2020. Autopsy Report with Clinical Pathological Correlation.
32410724 2020. The Lungs before and after COVID-19 Pneumonia.
