Target binding and uptake

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coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

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32199615 ä. Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses
32081428 2020. Structure analysis of the receptor binding of 2019-nCoV
32142651 2020. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
32203189 ä. Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
32047258 ä. Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
32265513 ä. SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion

ACE2
32275855 ä. Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
32279908 ä. Is the ACE2 Overexpression a Risk Factor for COVID-19 Infection?
32251718 2020. ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia
32201080 ä. Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection
32305506 ä. Renin-angiotensin system at the heart of COVID-19 pandemic
32291076 ä. EZH2-mediated H3K27me3 inhibits ACE2 expression
32299780 2020. Angiotensin-Converting Enzyme 2 as the Molecular Bridge Between Epidemiologic and Clinical Features of COVID-19
32299779 ä. What is the Role of Angiotensin Converting Enzyme 2 (ACE2) in COVID-19 Infection in Hypertensive, Diabetic Patients?
32227090 ä. The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2
32301968 ä. Binding of SARS-CoV-2 and angiotensin-converting enzyme 2: clinical implications
32133153 2020. Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations
32313207 ä. Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor
32264791 2020. Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2

tmprss2

others'

32130973 2020. A potential role for integrins in host cell entry by SARS-CoV-2
32272173 2020. Coronavirus membrane fusion mechanism offers a potential target for antiviral development