Magnesium CNNM accessory proteins
(Die Seite wurde neu angelegt: „ '''by PubMed''' PMC scrolldown {{tp|p=23027747|t=2012. Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cycl…“)
Aktuelle Version vom 13. Dezember 2021, 08:56 Uhr
by PubMed PMC scrolldown
23027747 2012. Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2).
21393841 2011. Purification, crystallization and preliminary crystallographic analysis of the CBS pair of the human metal transporter CNNM4.
21397062 2011. CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia.
19200527 2009. Mutations in CNNM4 cause recessive cone-rod dystrophy with amelogenesis imperfecta.
19200525 2009. Mutations in CNNM4 cause Jalili syndrome, consisting of autosomal-recessive cone-rod dystrophy and amelogenesis imperfecta.
32022389 2020. Expanding the genotypic spectrum of Jalili syndrome: Novel CNNM4 variants and uniparental isodisomy in a north American patient cohort.
29421294 2018. Jalili Syndrome: Cross-sectional and Longitudinal Features of Seven Patients With Cone-Rod Dystrophy and Amelogenesis Imperfecta.
24965791 2014. Identification and lateral membrane localization of cyclin M3, likely to be involved in renal Mg2+ handling in seawater fish.
32628538 2020. Gene expression profiling of proximal and distal renal tubules in Atlantic salmon (Salmo salar) acclimated to fresh water and seawater.
20147368 2010. Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca2+ and Mg2+ wasting.
25184538 2014. Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
15498024 2005. Manganese toxicity and Saccharomyces cerevisiae Mam3p, a member of the ACDP (ancient conserved domain protein) family.
27157538 2016. Altered expression of Mg(2+) transport proteins during Parkinson's disease-like dopaminergic cell degeneration in PC12 cells.
14723793 2004. Molecular cloning and characterization of the mouse Acdp gene family.
34089346 2021. ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs.
34440664 2021. Reactive Oxygen Species Downregulate Transient Receptor Potential Melastatin 6 Expression Mediated by the Elevation of miR-24-3p in Renal Tubular Epithelial Cells.
28224192 2017. Serum magnesium and the risk of prediabetes: a population-based cohort study.
34766907 2021. The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.
27856537 2016. Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.
34490037 2021. Case Report: CNNM2 Mutations Cause Damaged Brain Development and Intractable Epilepsy in a Patient Without Hypomagnesemia.
34604137 2021. CNNM2-Related Disorders: Phenotype and Its Severity Were Associated With the Mode of Inheritance.
29686978 2018. Novel Aspects of Renal Magnesium Homeostasis.
33967835 2021. Ion Transporters and Osmoregulation in the Kidney of Teleost Fishes as a Function of Salinity.
33600043 2021. The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2).
34072724 2021. The Combined Influence of Magnesium and Insulin on Central Metabolic Functions and Expression of Genes Involved in Magnesium Homeostasis of Cultured Bovine Adipocytes.
31842432 2019. Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
30994044 2019. Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm-Associated Regions to Potential Candidate Genes.
32571875 2020. PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth.
30593530 2018. Structure of a transporter domain emerges.
30341174 2018. The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg(2+) efflux activity.
27899452 2017. Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
26969161 2016. Inhibition of PRL-2.CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth.
24706765 2014. Mg2+-dependent interactions of ATP with the cystathionine-beta-synthase (CBS) domains of a magnesium transporter.
22399287 2012. Membrane topology and intracellular processing of cyclin M2 (CNNM2).
33883344 2021. Detection of novel and recurrent conjoined genes in non-Hodgkin B-cell lymphoma.
25347473 2014. Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
33571553 2021. Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH.
17608643 2007. Ancient conserved domain protein-1 binds copper and modifies its retention in cells.
25733456 2015. Genetic variations in magnesium-related ion channels may affect diabetes risk among African American and Hispanic American women.
23343670 2013. Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies.
29383729 2018. CrossTalk opposing view: CNNM proteins are not Na(+) /Mg(2+) exchangers but Mg(2+) transport regulators playing a central role in transepithelial Mg(2+) (re)absorption.
29344503 2017. Genetics of Magnesium Disorders.
34252449 2021. Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis.
34784661 2021. Hereditary kidney diseases associated with hypomagnesemia.
26446763 2015. The art of magnesium transport.
21983221 2011. Role of the distal convoluted tubule in renal Mg2+ handling: molecular lessons from inherited hypomagnesemia.
20519162 2010. Splice-variant 1 of the ancient domain protein 2 (ACDP2) complements the magnesium-deficient growth phenotype of Salmonella enterica sv. typhimurium strain MM281.
21199786 2010. Vascular biology of magnesium and its transporters in hypertension.
17536484 2007. Molecular components of vertebrate Mg2+-homeostasis regulation.
31347285 2019. A novel pathogenic missense variant in CNNM4 underlying Jalili syndrome: Insights from molecular dynamics simulations.
29322253 2018. Identification of a mutation in CNNM4 by whole exome sequencing in an Amish family and functional link between CNNM4 and IQCB1.
15840172 2005. Physical interaction and functional coupling between ACDP4 and the intracellular ion chaperone COX11, an implication of the role of ACDP4 in essential metal ion transport and homeostasis.
34158381 2021. Association of Serum Magnesium Levels With Risk of Intracranial Aneurysm: A Mendelian Randomization Study.
34021155 2021. Downregulation by CNNM2 of ATP5MD expression in the 10q24.32 schizophrenia-associated locus involved in impaired ATP production and neurodevelopment.
34202561 2021. Magnesium Deficiency Alters Expression of Genes Critical for Muscle Magnesium Homeostasis and Physiology in Mice.
30884817 2019. Cyanidin Increases the Expression of Mg(2+) Transport Carriers Mediated by the Activation of PPARalpha in Colonic Epithelial MCE301 Cells.
30241394 2018. Sodium Citrate Increases Expression and Flux of Mg(2+) Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells.
25540137 2015. Magnesium in man: implications for health and disease.
24699222 2014. CNNM2 mutations cause impaired brain development and seizures in patients with hypomagnesemia.
24339795 2013. Basolateral Mg2+ extrusion via CNNM4 mediates transcellular Mg2+ transport across epithelia: a mouse model.
20700443 2010. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
32997713 2020. Novel variant in the CNNM2 gene associated with dominant hypomagnesemia.
27254077 2016. P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis.
24194943 2013. Dental phenotype in Jalili syndrome due to a c.1312 dupC homozygous mutation in the CNNM4 gene.
24039880 2013. Magnesium homeostasis in cardiac myocytes of Mg-deficient rats.
30718434 2019. Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism.
33568487 2021. Structural basis for the Mg(2+) recognition and regulation of the CorC Mg(2+) transporter.
33859252 2021. Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.
32733084 2020. A FRET-based screening method to detect potential inhibitors of the binding of CNNM3 to PRL2.
28246390 2017. PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
32231419 2020. Effect of prolonged omeprazole administration on segmental intestinal Mg(2+) absorption in male Sprague-Dawley rats.
28586144 2017. Co-occurrence of Jalili syndrome and muscular overgrowth.
30278312 2018. Molecular expression of Mg(2+) regulator TRPM7 and CNNM4 in rat odontoblasts.
27150626 2016. Complementary role of CNNM2 in sperm motility and Ca(2+) influx during capacitation.
25449265 2014. Basolateral sorting of the Mg(2)(+) transporter CNNM4 requires interaction with AP-1A and AP-1B.
15318809 2004. All-trans retinoic acid-responsive genes identified in the human SH-SY5Y neuroblastoma cell line and their regulated expression in the nervous system of early embryos.
25833874 2015. Influences of schizophrenia risk variant rs7914558 at CNNM2 on brain structure.
24311551 2014. Effects of a novel schizophrenia risk variant rs7914558 at CNNM2 on brain structure and attributional style.
32397799 2020. SNHG7 Facilitates Hepatocellular Carcinoma Occurrence by Sequestering miR-9-5p to Upregulate CNNM1 Expression.
30026055 2019. CNNM2 homozygous mutations cause severe refractory hypomagnesemia, epileptic encephalopathy and brain malformations.
29421602 2018. Report of two unrelated families with Jalili syndrome and a novel nonsense heterozygous mutation in CNNM4 gene.
28246031 2017. Novel splice site mutation in CNNM4 gene in a family with Jalili syndrome.
20706282 2010. Cone-rod dystrophy and amelogenesis imperfecta (Jalili syndrome): phenotypes and environs.
30596515 2019. Tubular flow activates magnesium transport in the distal convoluted tubule.
12657465 2003. Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP).
24625443 2014. Identity-by-descent-guided mutation analysis and exome sequencing in consanguineous families reveals unusual clinical and molecular findings in retinal dystrophy.
27015884 2016. Localizing PRL-2 expression and determining the effects of dietary Mg(2+) on expression levels.
33356397 2021. Magnesium Supplementation Attenuates Pulmonary Hypertension via Regulation of Magnesium Transporters.
22990458 2013. The role of Mg2+ in immune cells.
25738804 2015. Association of six genetic variants with myocardial infarction.
27006114 2016. The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and is essential for reproduction.
31180948 2019. Magnesium-responsive genes are downregulated in diabetic patients after a three-month exercise program on a bicycle ergometer.
34302186 2021. Magnesium transport in the aglomerular kidney of the Gulf toadfish (Opsanus beta).
30457021 2019. PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3.
28033128 2017. Renal function of cyclin M2 Mg2+ transporter maintains blood pressure.
30705057 2019. Features, genetics and their correlation in Jalili syndrome: a systematic review.
30486934 2019. Ginsenoside Rh2 Inhibits Angiogenesis in Prostate Cancer by Targeting CNNM1.
28011227 2017. Effects of MgSO4 and magnesium transporters on 6-hydroxydopamine-induced SH-SY5Y cells.
32162608 2019. Magnesium transport and homeostasis-related gene expression in skeletal muscle of young and old adults: analysis of the transcriptomic data from the PROOF cohort Study.
30838594 2019. Protocol GenoDENT: Implementation of a New NGS Panel for Molecular Diagnosis of Genetic Disorders with Orodental Involvement.
34515155 2021. Diagnostic Dilemma in an Adolescent Girl with an Eating Disorder, Intellectual Disability, and Hypomagnesemia.
29672725 2019. Down-Regulated Expression of Magnesium Transporter Genes Following a High Magnesium Diet Attenuates Sciatic Nerve Crush Injury.
30670776 2019. Cnnm4 deficiency suppresses Ca(2+) signaling and promotes cell proliferation in the colon epithelia.
24632616 2015. The protein tyrosine phosphatase PRL-2 interacts with the magnesium transporter CNNM3 to promote oncogenesis.
27070327 2017. A new familial case of Jalili syndrome caused by a novel mutation in CNNM4.
21728811 2012. Cone-rod dystrophy associated with amelogenesis imperfecta in a child with neurofibromatosis type 1.
26117809 2015. Jalili syndrome presenting with situs inversus totalis and keratoconus: the first case in the Indian subcontinent.
18029156 2007. Magnesium transport in hypertension.
30685787 2019. Renal ischemia-reperfusion injury impairs renal calcium, magnesium, and phosphate handling in mice.
30726531 2019. Deregulated renal magnesium transport during lipopolysaccharide-induced acute kidney injury in mice.
27866273 2016. Omeprazole suppressed plasma magnesium level and duodenal magnesium absorption in male Sprague-Dawley rats.
27068403 2016. Human CNNM2 is not a Mg(2+) transporter per se.
23636770 2013. Tissue-specific expression and in vivo regulation of zebrafish orthologues of mammalian genes related to symptomatic hypomagnesemia.
15899945 2005. Functional characterization of ACDP2 (ancient conserved domain protein), a divalent metal transporter.
by PMC
30023603 2017. Mutational Analysis of a Conserved Glutamate Reveals Unique Mechanistic and Structural Features of the Phosphatase PRL-3.
23027747 2012. Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2).
32603001 2021. Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney.
29793662 2018. Magnesium Handling in the Kidney.
31559137 2019. Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1.
30388404 2018. Germline De Novo Mutations in ATP1A1 Cause Renal Hypomagnesemia, Refractory Seizures, and Intellectual Disability.
33135481 2020. NaCl cotransporter activity and Mg(2+) handling by the distal convoluted tubule.
27434427 2017. Screening of Living Kidney Donors for Genetic Diseases Using a Comprehensive Genetic Testing Strategy.
31807559 2019. Magnesium and liver disease.
21640700 2011. Cellular magnesium homeostasis.
27110677 2016. Prion-like Aggregation of Mitochondrial Antiviral Signaling Protein in Lupus Patients Is Associated With Increased Levels of Type I Interferon.
34541389 2022. Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/beta-catenin signaling.
28483640 2017. Characterization of constitutive and acid-induced outwardly rectifying chloride currents in immortalized mouse distal tubular cells.
33513920 2021. Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities.
33036384 2020. General Aspects of Metal Ions as Signaling Agents in Health and Disease.
32244350 2020. (20S)G-Rh2 Inhibits NF-kappaB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
25418090 2014. Physiological pathway of magnesium influx in rat ventricular myocytes.
33827531 2021. Identification of hub genes related to the progression of type 1 diabetes by computational analysis.
34217267 2021. Ultra-rare renal diseases diagnosed with whole-exome sequencing: Utility in diagnosis and management.
31651337 2019. Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis.
25868721 2015. Integrative network analysis reveals different pathophysiological mechanisms of insulin resistance among Caucasians and African Americans.
33268817 2021. Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity.
31643147 2019. Systematic analysis of concentrations of 52 elements in tumor and counterpart normal tissues of patients with non-small cell lung cancer.
31604444 2019. Hypomagnesemia is associated with new-onset diabetes mellitus following heart transplantation.
33035451 2020. Lactate Elicits ER-Mitochondrial Mg(2+) Dynamics to Integrate Cellular Metabolism.
32386544 2020. The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.
28389033 2017. Enamel: Molecular identity of its transepithelial ion transport system.
28810912 2017. Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.
24858416 2014. TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.
18021175 2007. Importance of melastatin-like transient receptor potential 7 and cations (magnesium, calcium) in human osteoblast-like cell proliferation.
34066059 2021. Upregulation of Chemoresistance by Mg(2+) Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells.
31705302 2020. Combination of furosemide and fludrocortisone as a loading test for diagnosis of distal renal tubular acidosis in a pediatric case.
30144020 2019. Exome sequencing identifies a novel frameshift variant causing hypomagnesemia with secondary hypocalcemia.
29619172 2017. Visualization of long-term Mg(2+) dynamics in apoptotic cells using a novel targetable fluorescent probe.
33095447 2021. Clinical application of a phenotype-based NGS panel for differential diagnosis of inherited kidney disease and beyond.
25287933 2015. Renal control of calcium, phosphate, and magnesium homeostasis.
24855283 2014. Distal convoluted tubule.
29352074 2018. Aldosterone, SGK1, and ion channels in the kidney.
33097786 2020. PRL-2 phosphatase is required for vascular morphogenesis and angiogenic signaling.
28919938 2017. Keep it on the edge: The post-mitotic midbody as a polarity signal unit.
29123461 2017. Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update.
32408221 2020. Advances in imaging of understudied ions in signaling: A focus on magnesium.
27906866 2017. Inherited and acquired disorders of magnesium homeostasis.
32652076 2020. PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation.
33923883 2021. Imbalance of Mg Homeostasis as a Potential Biomarker in Colon Cancer.
33504427 2021. A divalent boost from magnesium.
33242000 2020. Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory.
18497743 2008. Alu element-mediated gene silencing.
26273099 2015. Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6.
32369769 2020. A novel TRPM6 variant (c.3179T>A) causing familial hypomagnesemia with secondary hypocalcemia.
16002642 2005. Manganese transport and trafficking: lessons learned from Saccharomyces cerevisiae.
23942199 2014. New TRPM6 missense mutations linked to hypomagnesemia with secondary hypocalcemia.
16574103 2006. Extensive adenosine-to-inosine editing detected in Alu repeats of antisense RNAs reveals scarcity of sense-antisense duplex formation.
34368262 2021. Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.
33282857 2020. The Role of Disturbed Mg Homeostasis in Chronic Kidney Disease Comorbidities.
34777334 2021. Comprehensive Molecular and Cellular Characterization of Acute Kidney Injury Progression to Renal Fibrosis.
34276651 2021. Identifying Biomarkers from Transcriptomic Signatures in Renal Allograft Biopsies Using Deceased and Living Donors.
30333977 2018. Electrolyte and Acid-Base Disorders in the Renal Transplant Recipient.
27933050 2016. An Essential Factor for High Mg(2+) Tolerance of Staphylococcus aureus.
25674539 2015. TGF-beta1-Induced Epithelial-Mesenchymal Transition Promotes Monocyte/Macrophage Properties in Breast Cancer Cells.
31827445 2019. Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by (31)P Magnetic Resonance Spectroscopy, Than With Serum Magnesium.
19025793 2009. Gene position within chromosome territories correlates with their involvement in distinct rearrangement types in thyroid cancer cells.
27735924 2017. Copy-number variation is an important contributor to the genetic causality of inherited retinal degenerations.
15998448 2005. Genomic analysis of metabolic pathway gene expression in mice.
23346039 2012. Network graph analysis of gene-gene interactions in genome-wide association study data.
18415116 2008. Tight junctions and the modulation of barrier function in disease.
30911400 2019. A pediatric case of hypomagnesemia 1 (HOMG1) caused by novel compound heterozygous mutations in TRPM6.
30249747 2018. Heterogeneity of Ly6G(+) Ly6C(+) Myeloid-Derived Suppressor Cell Infiltrates during Staphylococcus aureus Biofilm Infection.
26679946 2015. TRPM channels and magnesium in early embryonic development.
19876832 2010. Gene expression in the placenta: maternal stress and epigenetic responses.
29849626 2018. Magnesium and Human Health: Perspectives and Research Directions.
33430309 2021. Mapping the SARS-CoV-2-Host Protein-Protein Interactome by Affinity Purification Mass Spectrometry and Proximity-Dependent Biotin Labeling: A Rational and Straightforward Route to Discover Host-Directed Anti-SARS-CoV-2 Therapeutics.
33153064 2020. Dietary Mg(2+) Intake and the Na(+)/Mg(2+) Exchanger SLC41A1 Influence Components of Mitochondrial Energetics in Murine Cardiomyocytes.
30845649 2019. Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators.
31336935 2019. Magnesium Is a Key Player in Neuronal Maturation and Neuropathology.
29891771 2018. Role of Magnesium Deficiency in Promoting Atherosclerosis, Endothelial Dysfunction, and Arterial Stiffening as Risk Factors for Hypertension.
29497325 2018. The importance of the thick ascending limb of Henle's loop in renal physiology and pathophysiology.
24966690 2014. Hypomagnesemia: a clinical perspective.
22878108 2012. Cell biology of ischemia/reperfusion injury.
34703991 2021. MR-PheWAS for the causal effects of serum magnesium on multiple disease outcomes in Caucasian descent.
33912817 2021. Identification and mechanistic analysis of an inhibitor of the CorC Mg(2+) transporter.
29093028 2018. Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes.
33428936 2021. Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR.
32439805 2020. The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion.
28623232 2017. The RING finger- and PDZ domain-containing protein PDZRN3 controls localization of the Mg(2+) regulator claudin-16 in renal tube epithelial cells.
27466368 2016. Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7).
21487014 2011. Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro.
32961078 2020. Identification of hub genes in colon cancer via bioinformatics analysis.
26703785 2016. Quantitative imaging of magnesium distribution at single-cell resolution in brain tumors and infiltrating tumor cells with secondary ion mass spectrometry (SIMS).
29383719 2018. CrossTalk proposal: CNNM proteins are Na(+) /Mg(2+) exchangers playing a central role in transepithelial Mg(2+) (re)absorption.
16793904 2006. Loading rat heart myocytes with Mg2+ using low-[Na+] solutions.
28679948 2017. PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms.
24856029 2014. Rare inherited kidney diseases: challenges, opportunities, and perspectives.
27872499 2017. Phosphatase PRL2 promotes oncogenic NOTCH1-Induced T-cell leukemia.
21199582 2011. Different responses to oxidized low-density lipoproteins in human polarized macrophages.
23506895 2013. The SLC41 family of MgtE-like magnesium transporters.
27303926 2016. Molecular and genetic inflammation networks in major human diseases.
16354698 2006. Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species.
29767241 2018. Transcriptome sequencing analysis reveals the effect of combinative treatment with lowintensity pulsed ultrasound and magnesium ions on hFOB1.19 human osteoblast cells.
32034291 2021. DNA methylation signature on phosphatidylethanol, not on self-reported alcohol consumption, predicts hazardous alcohol consumption in two distinct populations.
34188059 2021. Crystal structure of an archaeal CorB magnesium transporter.
29057934 2017. PTP4A1 promotes TGFbeta signaling and fibrosis in systemic sclerosis.
28747715 2017. ATP-dependent modulation of MgtE in Mg(2+) homeostasis.
30150663 2018. GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.
17139332 2006. Editor meets silencer: crosstalk between RNA editing and RNA interference.
31738409 2021. Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases.
29791908 2018. A de novo KCNA1 Mutation in a Patient with Tetany and Hypomagnesemia.
34836340 2021. Effect of Dapagliflozin and Magnesium Supplementation on Renal Magnesium Handling and Magnesium Homeostasis in Metabolic Syndrome.
30410355 2018. Inhibition of miR-10a-5p suppresses cholangiocarcinoma cell growth through downregulation of Akt pathway.
32001668 2020. Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo.
29492190 2018. Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor.
29254233 2017. A core program of gene expression characterizes cancer metastases.
29088818 2017. Transcriptome analysis of human colorectal cancer biopsies reveals extensive expression correlations among genes related to cell proliferation, lipid metabolism, immune response and collagen catabolism.
24927635 2014. Pathognomonic oral profile of Enamel Renal Syndrome (ERS) caused by recessive FAM20A mutations.
27234911 2017. Genetic causes of hypomagnesemia, a clinical overview.
33200256 2021. Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC.
29859177 2018. Targeting phosphatases of regenerating liver (PRLs) in cancer.
30030908 2018. Renal sodium and magnesium reabsorption are not coupled in a mouse model of Gordon syndrome.
29981200 2018. Sodium and magnesium in the distal convoluted tubule: no longer a couple?
27117800 2016. Primary renal magnesium wasting: an unusual clinical picture of exercise-induced symptoms.
28468833 2017. DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE.
18927203 2008. The unique nature of mg2+ channels.
31415562 2019. Genetic screens reveal novel major and minor players in magnesium homeostasis of Staphylococcus aureus.
27564576 2016. Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.
31163064 2019. Low extracellular magnesium does not impair glucose-stimulated insulin secretion.
25860617 2015. Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.
25133393 2014. MiR-152 may silence translation of CaMK II and induce spontaneous immune tolerance in mouse liver transplantation.
23737970 2013. Reverse engineering of modified genes by Bayesian network analysis defines molecular determinants critical to the development of glioblastoma.
22666440 2012. Ubiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca(2+)i-independent excitation-transcription coupling.
32788364 2020. Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis.
22918816 2012. Stem cells and corneal epithelial maintenance: insights from the mouse and other animal models.
25537281 2015. Glutamate Networks Implicate Cognitive Impairments in Schizophrenia: Genome-Wide Association Studies of 52 Cognitive Phenotypes.
33986418 2021. A screen of FDA-approved drugs identifies inhibitors of protein tyrosine phosphatase 4A3 (PTP4A3 or PRL-3).
34234242 2021. Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles.
33536578 2021. Five patients with disorders of calcium metabolism presented with GCM2 gene variants.
33293627 2020. SARS-CoV-2 receptor ACE2 is co-expressed with genes related to transmembrane serine proteases, viral entry, immunity and cellular stress.
31278342 2019. Glomerular expression pattern of long non-coding RNAs in the type 2 diabetes mellitus BTBR mouse model.
30742025 2019. Diabetes-induced hypomagnesemia is not modulated by metformin treatment in mice.
29352126 2018. Role of subcortical structures on cognitive and social function in schizophrenia.
28276483 2017. Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction.
30704530 2019. MagT1 regulated the odontogenic differentiation of BMMSCs induced byTGC-CM via ERK signaling pathway.
31823825 2019. Magnesium-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells by activating ERK/BMP2/Smads signaling.
32993136 2020. Network Controllability-Based Prioritization of Candidates for SARS-CoV-2 Drug Repositioning.
26981439 2016. Proton-pump inhibitor-induced hypomagnesemia: Current research and proposed mechanisms.
