Hydroxychloroquine

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*[https://www.medrxiv.org/content/10.1101/2020.04.26.20081059v1.full.pdf+html on safety, trial]
 
*[https://www.medrxiv.org/content/10.1101/2020.04.26.20081059v1.full.pdf+html on safety, trial]
 
*[https://www.nejm.org/doi/full/10.1056/NEJMoa2012410?query=C19&cid=DM91569_NEJM_Registered_Users_and_InActive&bid=193180241 Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19] ''substance is useless.''
 
*[https://www.nejm.org/doi/full/10.1056/NEJMoa2012410?query=C19&cid=DM91569_NEJM_Registered_Users_and_InActive&bid=193180241 Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19] ''substance is useless.''
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{{ttp|p=32437765|t=2020. Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19.|pdf=|usr=009}}
 
{{tp|p=32232419|t=ä. Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know |pdf=|usr=}}
 
{{tp|p=32232419|t=ä. Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know |pdf=|usr=}}
 
{{tp|p=32227189|t=ä. A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19 |pdf=|usr=}}
 
{{tp|p=32227189|t=ä. A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19 |pdf=|usr=}}

Version vom 8. Juli 2020, 15:16 Uhr

32437765 2020. Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19.


32232419 ä. Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know
32227189 ä. A Rush to Judgment? Rapid Reporting and Dissemination of Results and Its Consequences Regarding the Use of Hydroxychloroquine for COVID-19

32533263 2020. Intracellular ABCB1 as a Possible Mechanism to Explain the Synergistic Effect of Hydroxychloroquine-Azithromycin Combination in COVID-19 Therapy.


32147496 2020. Of chloroquine and COVID-19
32074550 2020. Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
32496938 2020. A case report of serious haemolysis in a glucose-6-phosphate dehydrogenase-deficient COVID-19 patient receiving hydroxychloroquine.
32321905 2020. Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database
32281583 2020. Update on use of chloroquine/hydroxychloroquine to treat coronavirus disease 2019 (COVID-19)
32265182 2020. Should chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review
32194981 2020. Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
32371558 2020. Hydroxychloroquine use in the COVID-19 patient
32150618 ä. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
32211771 ä. Could Chloroquine /Hydroxychloroquine Be Harmful in Coronavirus Disease 2019 (COVID-19) Treatment?
32211764 ä. Is Hydroxychloroquine a Possible Postexposure Prophylaxis Drug to Limit the Transmission to Healthcare Workers Exposed to Coronavirus Disease 2019?
32255489 ä. Towards Optimization of Hydroxychloroquine Dosing in Intensive Care Unit COVID-19 Patients
32306288 ä. Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties
32269021 2020. Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection
32345336 2020. Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2
32351851 ä. A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with Hydroxychloroquine
32340837 ä. Hydroxychloroquine in Covid-19: Does the end justify the means?
32247211 2020. Chloroquine and hydroxychloroquine in the treatment of COVID-19 with or without diabetes: A systematic search and a narrative review with a special reference to India and other developing countries
32321878 2020. Is GSK3beta a molecular target of chloroquine treatment against COVID-19?
32371138 ä. Chiral switches of chloroquine and hydroxychloroquine: potential drugs to treat COVID-19
32266694 ä. Chloroquine for COVID-19 Infection
32373183 2020. Chloroquine and hydroxychloroquine in the context of COVID-19
32338155 2020. Rheumotologitsts view on the use of hydroxychloroquine to treat COVID-19
32347923 ä. Chloroquine and hydroxychloroquine for COVID-19: implications for cardiac safety
32212513 2020. The Trial of Chloroquine in the Treatment of Corona Virus Disease 2019 COVID-19 and Its Research Progress in Forensic Toxicology
32363145 ä. An algorithm for managing QT prolongation in coronavirus disease 2019 (COVID-19) patients treated with either chloroquine or hydroxychloroquine in conjunction with azithromycin: Possible benefits of intravenous lidocaine
32363144 ä. Inpatient use of mobile continuous telemetry for COVID-19 patients treated with hydroxychloroquine and azithromycin
32341910 2020. SARS-CoV-2 infection in a patient on chronic hydroxychloroquine therapy: Implications for prophylaxis
32278018 ä. Cardiovascular risks of hydroxychloroquine in treatment and prophylaxis of COVID-19 patients: A scientific statement from the Indian Heart Rhythm Society
32335560 2020. Improving the efficacy of Chloroquine and Hydroxychloroquine against SARS-CoV-2 may require Zinc additives - A better synergy for future COVID-19 clinical trials
32205204 ä. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
32171740 ä. New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
32070753 2020. Chloroquine for the 2019 novel coronavirus SARS-CoV-2
C7152897 ä. Chloroquine as prophylactic agent against COVID-19?
32194152 ä. Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine
32145363 2020. Chloroquine and hydroxychloroquine as available weapons to fight COVID-19
32363157 2020. Chloroquine: Can it be a Novel Drug for COVID-19
32283236 ä. Does hydroxychloroquine combat COVID-19? A timeline of evidence
32330546 ä. Inpatient Use of Ambulatory Telemetry Monitors for COVID-19 Patients Treated with Hydroxychloroquine and/or Azithromycin
32281268 2020. G6PD and chloroquine: Selecting the treatment against SARS?CoV?2?
32356863 ä. Risk of QT Interval Prolongation Associated With Use of Hydroxychloroquine With or Without Concomitant Azithromycin Among Hospitalized Patients Testing Positive for Coronavirus Disease 2019 (COVID-19)
32356858 ä. Assessment of QT Intervals in a Case Series of Patients With Coronavirus Disease 2019 (COVID-19) Infection Treated With Hydroxychloroquine Alone or in Combination With Azithromycin in an Intensive Care Unit
32330277 2020. Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial
32339248 2020. Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial
32363144 ä. Inpatient use of mobile continuous telemetry for COVID-19 patients treated with hydroxychloroquine and azithromycin
32251731 ä. Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
32283237 ä. Hydroxychloroquine and ivermectin: a synergistic combination for COVID-19 chemoprophylaxis and/or treatment?
32283123 ä. Considerations for Drug Interactions on QTc in Exploratory COVID-19 (Coronavirus Disease 2019) Treatment
32196083 ä. COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression
32236561 ä. Combating COVID-19 with Chloroquine
32281481 2020. Challenges and cares to promote rational use of chloroquine and hydroxychloroquine in the management of coronavirus disease 2019 (COVID-19) pandemic: a timely review
32365215 2020. Behandling med 4-aminokinoliner vid covid-19 kan ge allvarliga biverkningar
32278373 2020. Regulators split on antimalarials for COVID-19
32359771 ä. Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19)
32304640 ä. Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base
32368738 2020. Excitement around hydroxychloroquine for treating COVID-19 causes challenges for rheumatology
32311322 ä. Chloroquine or hydroxychloroquine for prophylaxis of COVID-19
32311324 ä. Hydroxychloroquine prophylaxis for COVID-19 contacts in India
32322402 2020. Review on the global epidemiological situation and the efficacy of chloroquine and hydroxychloroquine for the treatment of COVID-19
32316270 2020. COVID-19, Chloroquine Repurposing, and Cardiac Safety Concern: Chirality Might Help
32231349 2020. Chloroquine in COVID-19: the evidence
32217166 2020. Chloroquine and COVID-19, where do we stand??
32240719 ä. No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection
32350818 ä. Chloroquine-induced QTc prolongation in COVID-19 patients
32344177 2020. In vitro testing of combined hydroxychloroquine and azithromycin on SARS-CoV-2 shows synergistic effect
32305500 ä. Chloroquine paradox may cause more damage than help fight COVID-19
32322397 2020. Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: trends, scope and relevance
32327397 ä. Safety signals for QT prolongation or Torsades de Pointes associated with azithromycin with or without chloroquine or hydroxychloroquine
32363212 ä. Review: Hydroxychloroquine and Chloroquine for Treatment of SARS-CoV-2 (COVID-19)
32292817 2020. Coalition: Advocacy for prospective clinical trials to test the post-exposure potential of hydroxychloroquine against COVID-19
32267301 ä. Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes
32347963 2020. An independent appraisal and re-analysis of hydroxychloroquine treatment trial for COVID-19
32247518 2020. COVID-19 and Chloroquine/Hydroxychloroquine: is there Ophthalmological Concern?

32349115 ä. Chloroquine and Hydroxychloroquine Retinal Toxicity Consideration in the Treatment of COVID-19


32289548 2020. Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
32247925 ä. Repurposing antimalarials and other drugs for COVID-19
32380315 ä. Continuous hydroxychloroquine or colchicine therapy does not prevent infection with SARS-CoV-2: Insights from a large healthcare database analysis
32348551 2020. Response to: Optimizing Hydroxychloroquine Dosing for Patients With COVID-19: An Integrative Modeling Approach for Effective Drug Repurposing: Quantitative Clinical Pharmacology Input to SARS-CoV-2 Therapeutics Should Be Based on Robust Data
32297988 2020. Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: A systematic review and meta-analysis
32173110 2020. A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19
32347894 2020. The Risks of Prescribing Hydroxychloroquine for Treatment of COVID-19-First, Do No Harm
32236562 2020. Treating COVID-19 with Chloroquine
32333649 2020. The friendly use of chloroquine in the COVID-19 disease: a warning for the G6PD-deficient males and for the unaware carriers of pathogenic alterations of the G6PD gene
32379955 ä. Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
32285489 2020. Chloroquine and Hydroxychloroquine in the Era of SARS - CoV2: Caution on Their Cardiac Toxicity
17806092 2008. Ferrocene Conjugates of Chloroquine and other Antimalarials: the Development of Ferroquine, a New Antimalarial
32164085 2020. Expert consensus on chloroquine phosphate for the treatment of novel coronavirus pneumonia

32313209 ä. Chloroquine reduces Th17 cell differentiation by stimulating T-bet expression in T cells


C7162107 2020. Chloroquin gegen Corona?
C7197234 2020. Safety concerns with higher dosage chloroquine in COVID-19 patients
C7197245 2020. Antimalarial use in COVID-19 patients requires close monitoring
32167254 2020. Epidemie de coronavirus et polemique sur la chloroquine
32270942 2020. Covid-19, dans les brouillards francais de l'hydroxychloroquine
32301315 2020. Covid-19, dans les brouillards de l'hydroxychloroquine (2)
32381323 ä. Acute hemolysis by hydroxycloroquine was observed in G6PD-deficient patient with severe COVD-19 related lung injury

32298965 2020. Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate
32380291 ä. Chloroquine-induced torsades de pointes in a patient with coronavirus disease 2019


32294495 ä. Chloroquine as a prophylactic agent against COVID-19?
C7184982 ä. Ventricular arrhythmia risk due to chloroquine / hydroxychloroquine treatment for COVID-19: Should it be given

32389720 ä. Excessive lysosomal ion-trapping of hydroxychloroquine and azithromycin


32402766 2020. Hydroxychloroquine as an aerosol might markedly reduce and even prevent severe clinical symptoms after SARS-CoV-2 infection
32451138 ä. ...surveillance ophtalmologique ...hydroxychloroquine e...
32408070 2020. Does zinc supplementation enhance the clinical efficacy of chloroquine/hydroxychloroquine to win todays battle against COVID-19?
32386744 ä. Uso de antipaludicos (antimalarials)...
24773578 2014. Chloroquine interferes with dengue?2 virus replication in U937 cells
32409150 ä. An evaluation of co-use of chloroquine or hydroxychloroquine plus azithromycin on cardiac outcomes: A pharmacoepidemiological study to inform use during the COVID19 pandemic
32286537 ä. Hydroxychloroquine: small effects in mild disease
32418730 ä. ?Off-label? use of hydroxychloroquine, azithromycin, lopinavir-ritonavir and chloroquine in COVID-19: A survey of cardiac adverse drug reactions by the French Network of Pharmacovigilance Centers
32331804 ä. Hydroxychloroquine and ?off-label? utilization in the treatment of oral conditions

28596841 2017. Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases


32387409 ä. Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France
32387694 ä. Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review
32442941 2020. Hidroxicloroquina. Mensajes desde la cardiologia en tiempos de pandemia por coronavirus.
32458599 2020. [Pharmacological characteristics of chloroquine and suggestions for its use in treatment of coronavirus disease 2019 (COVID-19)].
32075365 2020. [Expert consensus on chloroquine phosphate for the treatment of novel coronavirus pneumonia].
32498009 2020. Mass intake of hydroxychloroquine or chloroquine in the present context of the Covid-19 outbreak: Possible consequences in endemic malaria settings.
32500556 2020. Doubtful precipitation of hemolysis by hydroxychloroquine in glucose-6-phosphate dehydrogenase deficient patient with COVID-19 infection.
32474476 2020. Risk of using hydroxychloroquine as a treatment of COVID-19.
32432527 2020. Hydroxychloroquine against COVID-19: A critical appraisal of the existing evidence.
32380930 2020. Chloroquine and the potential adverse outcome in undiagnosed G6PD-deficient cases infected with COVID-19.
32435791 2020. Connecting hydroxychloroquine in vitro antiviral activity to in vivo concentration for prediction of antiviral effect: a critical step in treating COVID-19 patients.
32237918 2020. Chloroquine and hydroxychloroquine to treat COVID-19: between hope and caution.
32303497 2020. Chloroquine and COVID-19 - a potential game changer?



32321722 2020. To consider or not antimalarials as a prophylactic intervention in the SARS-CoV-2 (COVID-19) pandemic.
32317316 2020. Hydroxychloroquine reduces the risk of covid-19 in patients with rheumatic diseases: myth or reality?
32317315 2020. Is there a future for hydroxychloroquine/chloroquine in prevention of SARS-CoV-2 infection (COVID-19)?



32327429 2020. Can hydroxychloroquine protect patients with rheumatic diseases from COVID-19? Response to: 'Does hydroxychloroquine prevent the transmission of COVID-19?' by Heldwein and Calado and 'SLE, hydroxychloroquine and no SLE patients with COVID-19: a comment' by Joob and Wiwanitkit.
32295788 2020. Does hydroxychloroquine prevent the transmission of COVID-19?
32295786 2020. Festina lente: hydroxychloroquine, COVID-19 and the role of the rheumatologist.
32345618 2020. Response to 'Is there a future for hydroxychloroquine/chloroquine in prevention of SARS-CoV-2 infection (COVID-19)?' by Moiseev et al.



32474576 2020. Dose Optimization of Hydroxychloroquine for COVID-19: Do Blood Concentrations Matter?
32501756 2020. Association of Hydroxychloroquine with QTc Interval in Patients with COVID-19.
32267732 2020. Considerations for Drug Interactions on QTc in Exploratory COVID-19 Treatment.
32415690 2020. Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam.
32436730 2020. Use of Chloroquine and Hydroxychloroquine in COVID-19 and Cardiovascular Implications: Understanding Safety Discrepancies to Improve Interpretation and Design of Clinical Trials.
32347743 2020. Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection.
32430461 2020. Lack of efficacy of hydroxychloroquine in covid-19.
32503805 2020. Covid-19: Hydroxychloroquine was ineffective as postexposure prophylaxis, study finds.
32487664 2020. Covid-19: 146 researchers raise concerns over chloroquine study that halted WHO trial.
32269046 2020. Chloroquine and hydroxychloroquine in covid-19.
32469265 2020. Docking study of Chloroquine and Hydroxychloroquine interaction with SARS-CoV-2 spike glycoprotein-An in silico insight into the comparative efficacy of repurposing antiviral drugs.
32438459 2020. Efficacy, safety and cost-effectiveness of hydroxychloroquine in children with COVID-19: A call for evidence.
32473020 2020. Rationale of a loading dose initiation for hydroxychloroquine treatment in COVID-19 infection in the DisCoVeRy trial.
32457980 2020. Failure of hydroxychloroquine pre-exposure prophylaxis in COVID-19 infection? A case report.



32474918 2020. An open label cluster randomized controlled trial of chloroquine, hydroxychloroquine or only supportive care in patients admitted with moderate to severe COVID-19 (ARCHAIC) - Protocol publication.
32324363 2020. [A szerzett hosszu-QT-szindroma veszelye a koronavirus-jarvany idejen. Fokuszban a hidroxiklorokin]
32458488 2020. Potential negative effects of the free use of chloroquine to manage COVID-19 in Colombia.
32434282 2020. Hydroxychloroquine and Azithromycin to Treat Patients With COVID-19: Both Friends and Foes?
32448039 2020. In-silico strategies for probing chloroquine based inhibitors against SARS-CoV-2.
32295814 2020. Hydroxychloroquine and covid-19.
32496926 2020. Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19.
32488217 2020. The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin.




32496442 2020. Why G6PD Deficiency Should Be Screened Before COVID-19 Treatment With Hydroxychloroquine?
32490532 2020. HyPE study: hydroxychloroquine prophylaxis-related adverse events' analysis among healthcare workers during COVID-19 pandemic: a rising public health concern.
32492298 2020. Hydroxychloroquine for the Prevention of Covid-19 - Searching for Evidence.
32492293 2020. A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.
32479900 2020. Fatal arrhythmias: Another reason why doctors remain cautious about chloroquine/hydroxychloroquine for treating COVID-19.
32281213 2020. A systematic review of the prophylactic role of chloroquine and hydroxychloroquine in coronavirus disease-19 (COVID-19).
32473921 2020. Hydroxychloroquine for Covid-19 - When the pandemic runs faster than research.
32439366 2020. Arrhythmic profile and 24-hour QT interval variability in COVID-19 patients treated with hydroxychloroquine and azithromycin.
32450198 2020. A review on possible modes of action of chloroquine/hydroxychloroquine: repurposing against SAR-CoV-2 (COVID-19) pandemic.
32405156 2020. Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions reveal.
32514594 2020. Hydroxychloroquine pharmacokinetic in COVID-19 critically ill patients: an observational cohort study.
32474851 2020. Hydroxychloroquine and azithromycin as a treatment of COVID-19.
32393448 2020. The ICMR bulletin on targeted hydroxychloroquine prophylaxis for Covid-19: Need to interpret with caution.
32412404 2020. Outpatient hydroxychloroquine prescribing at a large academic health system during the COVID-19 pandemic.
32470627 2020. COVID-19 treatments, QT interval, and arrhythmic risk: The need for an international registry on arrhythmias.
32407884 2020. QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine/azithromycin.
32438018 2020. QT prolongation, torsades de pointes, and sudden death with short courses of chloroquine or hydroxychloroquine as used in COVID-19: A systematic review.
32535142 2020. Behavior of the PR Interval with Increasing Heart Rate in Patients with COVID-19.
32400382 2020. [Brug af hydroxychloroquin til COVID-19].
32400380 2020. [Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection].
32391667 2020. [A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19].
32402475 2020. Adverse drug reactions of hydroxychloroquine: Analysis of French pre-pandemic SARS-CoV2 pharmacovigilance data.
32348059 2020. COVID-19, dans les brouillards de l'hydroxychloroquine (4).
32320161 2020. Covid-19, dans les brouillards de l'hydroxychloroquine (3).
32525093 2020. Acute generalized exanthematous pustulosis induced by hydroxychloroquine prescribed for COVID-19.
32393664 2020. Hydroxychloroquine in Patients with Rheumatic Disease Complicated by COVID-19: Clarifying Target Exposures and the Need for Clinical Trials.
32451353 2020. Evidence of Protective Effect of Hydroxychloroquine on COVID-19.
32474406 2020. The rediscovery of hydroxychloroquine in allergic diseases in the COVID-19 era.
32463348 2020. Experience With Hydroxychloroquine and Azithromycin in the Coronavirus Disease 2019 Pandemic: Implications for QT Interval Monitoring.
32463308 2020. Chloroquine or Hydroxychloroquine for COVID-19: Is Cardiotoxicity a Concern?
32496241 2020. Hydroxychloroquine as prophylaxis or treatment for COVID-19: What does the evidence say?
32361760 2020. Comment on: COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression.
32442699 2020. Hydroxychloroquine effects on psoriasis: A systematic review and a cautionary note for COVID-19 treatment.
32439468 2020. Dermatologic manifestations of hydroxychloroquine therapy: a closer look at the nails.
32360856 2020. Can hydroxychloroquine be useful in the prevention of COVID-19? An Italian survey in dermatologic and rheumatologic patients already under treatment.
32348824 2020. Response to: "Risks of hydroxychloroquine use for COVID-19 prophylaxis".
32407770 2020. COVID-19, Clinical Trials and QT-Prolonging Prophylactic Therapy in Healthy Subjects: First, Do No Harm.
32401405 2020. Antihyperglycemic properties of hydroxychloroquine in patients with diabetes: Risks and benefits at the time of COVID-19 pandemic.
32474031 2020. Experience of short-term hydroxychloroquine and azithromycin in COVID-19 patients and effect on QTc trend.
32417904 2020. COVID-19 infection also occurs in patients taking hydroxychloroquine.
32425199 2020. Cardiovascular Safety of Potential Drugs for the Treatment of Coronavirus Disease 2019.

32390140 2020. Glucose-6-phosphate dehydrogenase deficiency-associated hemolysis and methemoglobinemia in a COVID-19 patient treated with chloroquine.


32359203 2020. A Rapid Systematic Review of Clinical Trials Utilizing Chloroquine and Hydroxychloroquine as a Treatment for COVID-19.
32517786 2020. Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.
32451259 2020. Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed.
32439074 2020. COVID-19 and Chloroquine/Hydroxychloroquine: Is There Ophthalmological Concern?
32449091 2020. Lack of viral clearance by the combination of hydroxychloroquine and azithromycin or lopinavir and ritonavir in SARS-CoV-2-related acute respiratory distress syndrome.
32422063 2020. Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19?
32383430 2020. Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine.
32314698 2020. Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19.
32475347 2020. Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS-evaluation of whole blood, plasma, and serum as sample matrices.
32331979 2020. Response to the editorial "COVID-19 in patients with cardiovascular diseases": Covid-19 treatment with hydroxychloroquine or chloroquine and azithromycin: A potential risk of Torsades de Pointes.
32525706 2020. The status surrounding chloroquine and other drugs as potential anti-infective agents for COVID-19.
32531808 2020. Impact of disease on plasma and lung exposure of chloroquine, hydroxy-chloroquine and azithromycin: application of PBPK modelling.
32520683 2020. Review on the clinical pharmacology of hydroxychloroquine sulfate for the treatment of COVID-19.
32424028 2020. Antimalarial use and arrhythmias in COVID-19 and rheumatic patients: a matter of dose and inflammation?
32424027 2020. Response to: 'Antimalarial use and arrhythmias in COVID-19 and rheumatic patients: a matter of dose and inflammation?' by Erre et al.
32241791 2020. To consider or not antimalarials as a prophylactic intervention in the SARS-CoV-2 (Covid-19) pandemic.
32519281 2020. Does Adding of Hydroxychloroquine to the Standard Care Provide any Benefit in Reducing the Mortality among COVID-19 Patients?: a Systematic Review.
32415419 2020. Smooth or Risky Revisit of an Old Malaria Drug for COVID-19?
32459529 2020. Hydroxychloroquine or Chloroquine for Treatment or Prophylaxis of COVID-19: A Living Systematic Review.

32514696 2020. Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam: an Increasing Concern in the COVID-19 Pandemic.


32418181 2020. Recommendations for the measurement of the QT interval during the use of drugs for COVID-19 infection treatment. Updatable in accordance with the availability of new evidence.
32405664 2020. Hydroxychloroquine and azithromycin as potential treatments for COVID-19; clinical status impacts the outcome.
32401368 2020. Conduction abnormalities in hydroxychloroquine add on therapy to lopinavir/ritonavir in COVID-19.
32534369 2020. Hydroxychloroquine/ chloroquine as a treatment choice or prophylaxis for Covid-19 at the primary care level in developing countries: A Primum non Nocere dilemma.
32362051 2020. Drug reaction with eosinophilia and systemic symptoms syndrome to hydroxychloroquine, an old drug in the spotlight in the COVID-19 era.
32401410 2020. Acute generalized exanthematous pustulosis after COVID-19 treatment with hydroxychloroquine.
32253799 2020. Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine.
32373993 2020. Efficacy of chloroquine and hydroxychloroquine in the treatment of COVID-19.
32356580 2020. QTc evaluation in COVID-19 patients treated with chloroquine/hydroxychloroquine.
32495580 2020. [Pharmacovigilance study on drug-induced cardiac injury during treatment of COVID-19].
32426364 2020. Hydroxychloroquine: A Familiar Agent to Combat the Pandemic of COVID-19.
32391371 2020. SARS-CoV-2 and the Use of Chloroquine as an Antiviral Treatment.
32391370 2020. The Role of Hydroxychloroquine in Coronavirus Disease 2019. A Versatile Tool at the Service of Humanity.
32350928 2020. Rethinking the role of hydroxychloroquine in the treatment of COVID-19.
32495148 2020. A New Drug-Drug Interaction Between Hydroxychloroquine and Metformin? A Signal Detection Study.
32324284 2020. COVID-19 infection and treatment with hydroxychloroquine cause severe haemolysis crisis in a patient with glucose-6-phosphate dehydrogenase deficiency.
32417708 2020. "Hydroxychloroquine in patients with COVID-19: A Systematic Review and meta-analysis."
32485061 2020. Incidence and Determinants of QT Interval Prolongation in COVID-19 Patients Treated with Hydroxychloroquine and Azithromycin.
32385749 2020. Hydroxychloroquine and ritonavir for COVID-19 infection: a possible synergic toxicity for retinal pigmented epithelium.
32392282 2020. Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State.
32450109 2020. Chloroquine or hydroxychloroquine for COVID-19: why might they be hazardous?
32418894 2020. A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials.
32533592 2020. Pharmacist's perspective on HCQ treatment of COVID-19.
32460458 2020. In vitro activity of lopinavir/ritonavir and hydroxychloroquine against severe acute respiratory syndrome coronavirus 2 at concentrations achievable by usual doses.
32350818 2020. Chloroquine-induced QTc prolongation in COVID-19 patients.
32425245 2020. Hidroxicloroquina en el tratamiento del COVID-19: como utilizarla a la espera de evidencia cientifica concluyente.
32430286 2020. The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?
32394513 2020. Chloroquine and hydroxychloroquine for COVID-19: A word of caution.
32395001 2020. Evidencia viva como respuesta a las controversias en el uso de antimalaricos en COVID-19.
32528194 2020. Perspectives on repositioning chloroquine and hydroxychloroquine for the treatment of Covid-19.
32501367 2020. Chloroquine dosage regimens in patients with COVID-19: Safety risks and optimization using simulations.
32418114 2020. Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19.
32551892 2020. Update Alert: Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? Living Practice Points From the American College of Physicians.
32485391 2020. Hydroxychloroquine-azithromycin for COVID-19 - Warranted or dangerous?
32360423 2020. Malaria prophylaxis approach during COVID-19 pandemic.
32473812 2020. Chloroquine and hydroxychloroquine in the management of COVID-19: Much kerfuffle but little evidence.
32418732 2020. Chloroquine and hydroxychloroquine during pregnancy: What do we know?
32457932 2020. Chloroquine, hydroxychloroquine and COVID-19.
32557011 2020. A Double-Edged Sword-Cardiovascular Concerns of Potential Anti-COVID-19 Drugs.
32542893 2020. Acute generalized exanthematous pustulosis induced by empiric hydroxychloroquine for presumed COVID-19.
32554525 2020. Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data.
32565195 2020. Chloroquine cardiac effects and toxicity.A short update.
32556143 2020. Compassionate use of hydroxychloroquine in clinical practice for patients with mild to severe Covid-19 in a French university hospital.
32540958 2020. Hydroxychloroquine for covid-19: the end of the line?
32588427 2020. QT interval prolongation under hydroxychloroquine/ azithromycin association for inpatients with SARS-CoV-2 lower respiratory tract infection.
32552642 2020. Facts and myths: Efficacies of repurposing chloroquine and hydroxychloroquine for the treatment of COVID-19.
32592507 2020. Hydroxychloroquine, COVID-19 and diabetes. Why it is a different story.
32588188 2020. Comment on "Smooth or Risky Revisit of an Old Malaria Drug for COVID-19?"
32567262 2020. A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance.
32558210 2020. Clearance of chloroquine and hydroxychloroquine by the Seraph(R) 100 Microbind(R) Affinity blood filter - approved for the treatment of COVID-19 patients.

32579059 2020. Screening of Chloroquine, Hydroxychloroquine and its derivatives for their binding affinity to multiple SARS-CoV-2 protein drug targets.
32571115 2020. Cutaneous side effects of hydroxychloroquine in health care workers in a COVID referral hospital - implications for clinical practice.


32564047 2020. Chloroquine in controlling biological infections.
32323646 2020. Chloroquine and Hydroxychloroquine for the Prevention or Treatment of COVID-19 in Africa: Caution for Inappropriate Off-label Use in Healthcare Settings.
32571633 2020. Hydroxychloroquine as Prophylaxis for Coronavirus SARS-CoV-2 Infection: Review of the Ongoing Clinical Trials.
32603983 2020. Psychiatric adverse events with hydroxychloroquine during COVID-19 pandemic.
32409561 2020. Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial.
32409486 2020. Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data.
32350872 2020. COVID-19 and (hydroxy)chloroquine-azithromycin combination: Should we take the risk for our patients?
32562278 2020. Novel Approach for Low-Dose Pulmonary Delivery of Hydroxychloroquine in COVID-19.
32427154 2020. Hydroxychloroquine-based treatments in the CoViD-19 pandemic.
32428074 2020. Chloroquine and hydroxychloroquine repositioning in times of COVID-19 pandemics, all that glitters is not gold.
32600860 2020. Chloroquine and COVID-19: A western medical and scientific drift?
32610165 2020. Effects of Hydroxychloroquine Treatment on QT Interval.

32601063 2020. Covid-19: Oxford team begins vaccine trials in Brazil and South Africa to determine efficacy.
least regulated zones biggest negroe populations


32559820 2020. Model informed dosing of Hydroxycholoroquine in COVID-19 patients: Learnings from the recent experience, remaining uncertainties and Gaps.
32602956 2020. The many mechanisms of action of Chloroquine: to use or not to use (in COVID-19) that is the question.
32468425 2020. An Updated Systematic Review of the Therapeutic Role of Hydroxychloroquine in Coronavirus Disease-19 (COVID-19).
32392332 2020. Hydroxychloroquine in COVID-19 patients: what still needs to be known about the kinetics.
32470568 2020. Clinical evidence for repurposing chloroquine and hydroxychloroquine as antiviral agents: a systematic review.
32422406 2020. Safety considerations for chloroquine and hydroxychloroquine in the treatment of COVID-19.
32384908 2020. Chloroquine for COVID-19: rationale, facts, hopes.
32268005 2020. Hydroxychloroquine for Treatment of SARS-CoV-2 Infection? Improving Our Confidence in a Model-Based Approach to Dose Selection.
32401962 2020. Do we have enough evidence to use chloroquine/hydroxychloroquine as a public health panacea for COVID-19?
32575065 2020. Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection.
32285930 2020. Optimizing Hydroxychloroquine Dosing for Patients With COVID-19: An Integrative Modeling Approach for Effective Drug Repurposing.
32495226 2020. Hydroxychloroquine and chloroquine in COVID-19: should they be used as standard therapy?
32348544 2020. Response to "Quantitative Clinical Pharmacology INPUT to SARS-CoV-2 Therapeutics Should be Based on Robust Data": Data-Driven Dosing Recommendations are Urgently Needed for Hydroxychloroquine in COVID-19 Patients: Response to Letter to the Editor.
32344449 2020. Finding the Dose for Hydroxychloroquine Prophylaxis for COVID-19: The Desperate Search for Effectiveness.
32320477 2020. Chloroquine Dosing Recommendations for Pediatric COVID-19 Supported by Modeling and Simulation.
32607690 2020. Does Adding of Hydroxychloroquine to the Standard Care Provide any Benefit in Reducing the Mortality among COVID-19 Patients?: a Systematic Review.
32559589 2020. Assessing the risk of seizures with chloroquine or hydroxychloroquine therapy for COVID-19 in persons with epilepsy.
32574312 2020. Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.
32553587 2020. COVID-19 and hydroxychloroquine: Is the wonder drug failing?
32549293 2020. A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation.
32593867 2020. Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis.
32330312 2020. Does pandemic justify the use of hydroxychloroquine for treatment and prevention of COVID-19 in India?
32330276 2020. Caution Needed on the Use of Chloroquine and Hydroxychloroquine for Coronavirus Disease 2019.
32411941 2020. When there is a pandemic there is no time to waste: should we have hydroxychloroquine in our armoury against COVID-19 infected patients?
32562480 2020. Systematic review of registered trials of Hydroxychloroquine prophylaxis for COVID-19 health-care workers at the first third of 2020.
32536565 2020. Living evidence in response to controversies about the use of antimalarials in COVID-19.
32540396 2020. Safety use of hydroxychloroquine and its combination with azithromycin in the context of Sars-CoV-2 outbreak: Clinical experience in a Belgian tertiary center.


32561608 2020. Role of antimalarials in COVID-19: observational data from a cohort of rheumatic patients.
32523144 2020. Protocolo para la prevencion de arritmias ventriculares debido al tratamiento en pacientes con COVID-19.
32460209 2020. The effect of potential therapeutic agents on QT interval in patients with COVID-19 Infection: The importance of close monitoring and correction of electrolytes.

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