Structure of covid19

Version vom 1. Juni 2020, 13:30 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

general aspects
32254054 2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191
32254048 2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191
32092911 2020. Rigidity of the Outer Shell Predicted by a Protein Intrinsic Disorder Model Sheds Light on the COVID-19 (Wuhan-2019-nCoV) Infectivity
32330414 ä. The Architecture of SARS-CoV-2 Transcriptome
32289263 ä. An Infectious cDNA Clone of SARS-CoV-2

genomic variablity

• ...is high

nucleocapsid protein
32363136 ä. Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

spike protein
32057769 2020. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
32155444 ä. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

3CL proteinase
32293875 ä. Why Are Lopinavir and Ritonavir Effective against the Newly Emerged Coronavirus 2019? Atomistic Insights into the Inhibitory Mechanisms
32239142 ä. Potential covalent drugs targeting the main protease of the SARS-CoV-2 coronavirus
32308266 2020. Molecular docking and dynamics simulation of FDA approved drugs with the main protease from 2019 novel coronavirus
32313296 2020. Identification of potential binders of the main protease 3CLpro of the COVID-19 via structure-based ligand design and molecular modeling

nsp1 protein
32336957 2020. Combination of Biodata Mining and Computational Modelling in Identification and Characterization of ORF1ab Polyprotein of SARS-CoV-2 Isolated from Oronasopharynx of an Iranian Patient

32311462 2020. On the molecular determinants of the SARS-CoV-2 attack
32129843 ä. Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients
32129842 ä. A glimpse into the origins of genetic diversity in SARS-CoV-2
32229288 ä. Molecular characterization of SARS-CoV-2 from the first case of COVID-19 in Italy
32341946 2020. Chaos game representation dataset of SARS-CoV-2 genome
32301390 2020. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction
32178593 2020. Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26
31987001 2020. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

32265007 2020. Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe
32210741 2020. Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target
32194944 2020. Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL pro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates
32300673 2020. Genomic characterization of a novel SARS-CoV-2
32353474 ä. Genotyping coronavirus SARS-CoV-2: Methods and implications
32362650 2020. Genomic analysis of SARS-CoV-2 strains among Indians returning from Italy, Iran & China, & Italian tourists in India
32362648 2020. Transmission electron microscopy imaging of SARS-CoV-2
32242873 2020. Full-genome sequences of the first two SARS-CoV-2 viruses from India

32092483 2020. Genetic diversity and evolution of SARS-CoV-2
32335334 ä. Emerging genetic diversity among clinical isolates of SARS-CoV-2: Lessons for today

32004758 2020. Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event

32361692 2020. How the COVID-19 Overcomes the Battle? An Approach to Virus Structure
32306836 2020. Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
32145215 ä. Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2
31994738 2020. The 2019?new coronavirus epidemic: Evidence for virus evolution
32027036 2020. Genomic variance of the 2019?nCoV coronavirus
32265180 ä. Genotype and phenotype of COVID-19: Their roles in pathogenesis
32178970 2020. Composition of human-specific slow codons and slow di-codons in SARS-CoV and 2019-nCoV are lower than other coronaviruses suggesting a faster protein synthesis rate of SARS-CoV and 2019-nCoV

32320687 ä. Phylogenetic Analysis and Structural Modeling of SARS-CoV-2 Spike Protein Reveals an Evolutionary Distinct and Proteolytically Sensitive Activation Loop
32200634 ä. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1
32321524 2020. Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant
32357959 2020. An 81 nucleotide deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020)

32350227 2020. Characteristics of SARS-CoV-2 isolated from asymptomatic carrier in Tokyo
32007145 2020. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
32342926 2020. Properties of Coronavirus and SARS-CoV-2
32194253 ä. Molecular basis of COVID-19 relationships in different species: a one health perspective
32302675 ä. Comparative computational analysis of SARS-CoV-2 nucleocapsid protein epitopes in taxonomically related coronaviruses
32165386 2020. Complete Genome Sequence of a 2019 Novel Coronavirus (SARS-CoV-2) Strain Isolated in Nepal

32371472 2020. SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis
32123347 ä. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
32303698 ä. A map of SARS-CoV-2 and host cell interactions

32149036 2020. Identification of Coronavirus Isolated from a Patient in Korea with COVID-19
32357545 2020. Emergence of Drift Variants That May Affect COVID-19 Vaccine Development and Antibody Treatment

32269081 2020. Phylogenetic network analysis of SARS-CoV-2 genomes
32009228 2020. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission
32277040 2020. Structure of the RNA-dependent RNA polymerase from COVID-19 virus
32075877 2020. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
C7152894 ä. A COMPREHENSIVE ANALYSIS OF GENOME COMPOSITION AND CODON USAGE PATTERNS OF EMERGING CORONAVIRUSES
C7085496 ä. Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV)
32218151 2020. Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins
32098422 2020. Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV
32366025 2020. Codon Usage and Phenotypic Divergences of SARS-CoV-2 Genes
32351056 2020. Decoding the evolution and transmissions of the novel pneumonia coronavirus (SARS-CoV-2 / HCoV-19) using whole genomic data

32348474 2020. Expanding our understanding of the role polyprotein conformation plays in the coronavirus life cycle

32367648 2020. SARS-CoV-2 variants: Relevance for symptom granularity, epidemiology, immunity (herd, vaccines), virus origin and containment?
32342578 2020. The Importance Of Naturally Attenuated Sars-Cov-2 In The Fight Against Covid-19
32291894 2020. Cytosine drives evolution of SARS-CoV-2