Contents

Version vom 10. Mai 2020, 17:03 Uhr

the topic map of a 30 kB genome

Further reading

• search pubmed and other resources
• journal publishers collections
• ppl who want to hear your ideas on covid19
• discussion groups covid19

current state of coviki.org

• PubMed selected papers unsorted to be listed in contents topics
• coviki state of development

general reviews covid19 disease

32150360 2020. Features, Evaluation and Treatment Coronavirus (COVID-19)
32267678 ä. COVID-19: A Call for Physical Scientists and Engineers adressing off-topic research contributors
32335749 ä. How Could This Happen?: Narrowing Down the Contagion of COVID-19 and Preventing Acute Respiratory Distress Syndrome (ARDS)

structure covid19

general aspects
32254054 2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191
32254048 2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191

genomic variablity

• ...is high

nucleocapsid protein
32363136 ä. Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

Covid19 target binding and uptake

Covid19 cytopathic effects

Covid19 innate sensing

Covid19 local tissue reaction

• rev. on covid immunology

Covid19 cytokine storm | hemophagocytic lymphohistiocytosis hlh

• on hlh

32267081 2020. Continuous Intravenous Anakinra Infusion to Calm the Cytokine Storm in Macrophage Activation Syndrome
32267072 2020. IV anakinra for macrophage activation syndrome may hold lessons for treatment of cytokine storm in the setting of COVID19

ARDS respiratory support

32313662 2020. Veno-venous extracorporeal membrane oxygenation for severe pneumonia: COVID-19 case in Japan

pulmonary embolism / coagulation covid19

• thrombotic late reactions
• german autopsy data

32331965 ä. Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach

heart covid19

32310612 2020. Cardiac Manifestations Of Coronavirus (COVID-19)

neurology, ophthalmology, orl covid19

32310553 2020. Ophthalmic Manifestations Of Coronavirus (COVID-19)
32119409 2020. Neuroanatomy, Nucleus Gustatory PDF direct
32295727 ä. Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report
32343122 2020. Updates on What ACS Reported: Emerging Evidences of COVID-19 with Nervous System Involvement
32320211 ä. Neurological Insights of COVID-19 Pandemic
C7160911 ä. SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection
32348111 ä. Is the Collapse of the Respiratory Center in the Brain Responsible for Respiratory Breakdown in COVID-19 Patients?
32167747 2020. Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host?Virus Interaction, and Proposed Neurotropic Mechanisms
32233443 2020. Letter to the Editor ...Evidence of the COVID-19 Virus Targeting the CNS...
32367205 ä. SARS-CoV-2 can induce brain and spine demyelinating lesions

dermatology covid19

32315073 2020. Cutaneous Clinico-Pathological Findings in three COVID-19-Positive Patients Observed in the Metropolitan Area of Milan, Italy

gastroenterology and hepatology covid19

32291373 2020. Gastrointestinal Presentation in COVID-19 in Indonesia: A Case Report

Covid19 hypoxia tolerance

• happy hypoxia experience

Covid19 putative risk factors

• ACEI/AT1RA not risky ?
• dextrometorphan (antitussive compd)

risk populations covid19

Diabetes, Obesity
32249357 ä. Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic ACEi ARBs
32363137 ä. Anti-RAS drugs and SARS-CoV-2 infection

Covid19 secretion

anything MERS

anything SARS

anything Influenza

anything Influenza 1918

• history.com

anything Ebola

Pathobiology Covid19

32273135 ä. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases

Disease Models Covid19

Diagnosing (Virus / Antibodies) Covid19

• on false-positives
• on positives in non-vertebrate samples
• antibody test roche

32293168 ä. Rapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal Swab Specimens Using Field-Effect Transistor-Based Biosensor
32223179 ä. Diagnosing COVID-19: The Disease and Tools for Detection
32281785 ä. Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection

Diagnosing (Lung CT, Sonography) Covid19

32276754 ä. CT Manifestation of COVID-19 Pneumonia; Role of Multiplanar Imaging
32204990 2020. Imaging Features of Coronavirus disease 2019 (COVID-19): Evaluation on Thin-Section CT
32204987 2020. Coronavirus Disease (COVID-19): Spectrum of CT Findings and Temporal Progression of the Disease
32335002 ä. COVID-19 Evaluation by Low-Dose High Resolution CT Scans Protocol
32331965 ä. Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach
32327295 ä. COVID-19 or Pulmonary Contusion? A Diagnostic Dilemma
32312654 ä. COVID-19 Pulmonary Involvement: Is Really an Interstitial Pneumonia?
32291374 2020. The Importance of Chest CT Scan in COVID-19

Clinical Guidelines Covid19

Clinical Trials Covid19

• at clinicaltrials.gov 1323 running

Candidate Compounds Covid19

reviews candidate compounds covid19
32226821 2020. Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
32292689 ä. Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
32318328 ä. D3Targets-2019-nCoV: a webserver for predicting drug targets and for multi-target and multi-site based virtual screening against COVID-19

Hydroxychloroquine retarget

• check retina status known toxicity
• 91% benefit
• approval russia
• scale up production
• on safety, trial

Chlorpromazine retarget

• paper

Zinc add-on

• call for trial

Remdesivir retarget

• one hospital on...

Lauric acid nat. compd.

• call for trial

Nicotine nat. toxin

• france

Niclosamide
32125140 ä. Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

Microbiome as target
32356654 ä. Considering the Effects of Microbiome and Diet on SARS-CoV-2 Infection: Nanotechnology Roles

ACE2 as target
32286790 ä. Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2

Garlic extracts
32363255 ä. Investigation into SARS-CoV-2 Resistance of Compounds in Garlic Essential Oil

Dipyridamole retarget
32318327 ä. Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19

Various Leads

• 9 retargeted: ternatin4, zotatifin, plitidepsin; haloperidol, melperone, clemastine, cloperastine, pb28, progesterone
• paper in nature

hope: Vaccination Covid19

• mrna-1273, moderna

hope: Therapeutic antibodies

• anti covid mab
• acmab 47d11

hope: Chemoprevention Covid19

hope: Antiviral agents Covid19

hope: Lung regeneration and repair after Covid19

hope: Neurology rehab

Remission & Recurrence

• 10% recurrence rate

Risk group : Nursing home inmates

• no sunlight no vitamin d

Socio-psychiatric aspects of the status hygienicus

Economic aspects of the status hygienicus

Educational aspects of the status hygienicus

Safer Work and status hygienicus

jail, abattoirs... crowded indoor places...

Biophysics of aerosols

Aerosolic infection prevention

Other routes of infection

• semen

passive protective devices

masks
32329337 ä. Aerosol Filtration Efficiency of Common Fabrics Used in Respiratory Cloth Masks
32368894 ä. Can N95 Respirators Be Reused after Disinfection? How Many Times?

Running your hospital

32335003 ä. Proposed imaging guidelines for pregnant women suspected of having COVID-19 Blurred diagnostic approaches
32377597 ä. Need for Caution in the Diagnosis of Radiation Pneumonitis in the COVID-19 Pandemic

Diagnostic and Interv. Radiology
32303440 2020. Radiology Management and COVID-19 in Resource Limited Setting
32336647 ä. COVID-19 Protection Guidelines in Outpatient Medical Imaging Centers
32113880 ä. Corona Virus International Public Health Emergencies: Implications for Radiology Management

Hemonc, Radiotherapy, BMT
32375142 2020. Perspective: SARS-CoV-2, COVID-19 and Haematologists
32377596 ä. Experiencing the Surge: Report from a Large New York Radiation Oncology Department During the COVID-19 Pandemic
32313845 ä. Radiation Therapy in King County, Washington During the COVID-19 Pandemic: Balancing Patient Care, Transmission Mitigation, and Resident Training

Neurosurgery, ORL surgery
32222820 ä. Neurosurgery during the COVID-19 pandemic: update from Lombardy, northern Italy
32314059 ä. The impact of COVID-19 on neurosurgeons and the strategy for triaging non-emergent operations: a global neurosurgery study
32291593 ä. Our darkest hours (being neurosurgeons during the COVID-19 war)
32271745 2020. Surgical management of head and neck tumours during the SARS-CoV (Covid-19) pandemic

Psychiatry (on general population)
32333227 ä. Mobilization of Telepsychiatry in Response to COVID-19?Moving Toward 21st Century Access to Care

Host, Vector, One Health aspects of Covid19

Tracing the Origin of Covid19

Mass Psychology of Covid19

• positives bannend from military

social deprivation, suicide

• inc suicide

Getting Criminal

• reasearcher killed

Transformation of the World accepting and abusing the Virus Thread

After civilization breakdown

• famine

KIA

• Paul Cary

various topics

32227916 ä. Nano Research for COVID-19

various case reports covid19

32291376 2020. Clinical Progression of COVID-19 Patient with Extended Incubation Period, Delayed RT-PCR Time-to-positivity, and Potential Role of Chest CT-scan

history of covid19 exploration

32291365 2020. Diagnosing COVID-19: Did We Miss Anything?