AV Molnupiravir

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drug: Molnupiravir, MK-4482, EIDD-2801

Lokalpressebericht
clintrials molnupiravir
Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets Acting through the induction of error catastrophe in virus replication4,12, NHC has broad-spectrum anti-RNA virus activity. In addition to ameliorating acute disease, we have demonstrated in a guinea pig transmission model that NHC effectively blocks the spread of influenza virus from infected animals to untreated contact animals.
short editorial

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-Molnupiravir, MK-4482, EIDD-2801
+{{up|PHA antivirals by mechanism}}
+----
+drug: Molnupiravir, MK-4482, EIDD-2801
+----
 *[https://www.infranken.de/ratgeber/gesundheit/coronavirus/covid19-medikament-blockiert-coronavirus-komplett-forscher-mit-durchbruch-art-5127468 Lokalpressebericht]
 *[https://clinicaltrials.gov/ct2/show/NCT04575584 clintrials molnupiravir]
-*[https://www.nature.com/articles/s41564-020-00835-2 Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets]
+*[https://www.nature.com/articles/s41564-020-00835-2 Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets] ''Acting through the induction of error catastrophe in virus replication4,12, NHC has broad-spectrum anti-RNA virus activity. In addition to ameliorating acute disease, we have demonstrated in a guinea pig transmission model that NHC effectively blocks the spread of influenza virus from infected animals to untreated contact animals.''
 *[https://www.news-medical.net/news/20201203/New-antiviral-drug-completely-suppresses-SARS-CoV-2-transmission-within-24-hours.aspx short editorial]