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'''the topic map of a 30 kB genome'''
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'''coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.'''
  
== Further reading ==
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{{tp|p=32399342|t=2020. A Case of a COVID-19-positive Patient.|pdf=|usr=008}}
*[http://www.moremed.org/SiteSearch.php?S1=%28covid19+OR+covid-19+OR+covid19+OR+sars-cov2+OR+sars-cov-2+OR+2019-ncov+OR+2019ncov%29&S2=&S3=&submit=submit&px1=proxy.nationallizenzen.de&px2=&px3=&px4=&R=all&Y0=1500&Y1=2025 search pubmed and other resources]
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*[[journal publishers collections]]
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*[[ppl who want to hear your ideas on covid19]]
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*[[discussion groups covid19]]
+
  
== current state of coviki.org==
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{{dNEJMLancet}}
*[[PubMed selected papers unsorted to be listed in contents topics]]
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*[[coviki state of development]]
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== general reviews covid19 disease ==
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visit '''[http://www.coviki.org this websites homepage]''' to get
{{tp|p=32150360|t=2020. Features, Evaluation and Treatment Coronavirus (COVID-19)|pdf=|usr=}}
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an expert 3d view on the topics as i assorted them retrospectively
{{tp|p=32267678|t=ä. COVID-19: A Call for Physical Scientists and Engineers |pdf=|usr=}} adressing off-topic research contributors
+
the 3fold separation of the clinical issues is not well
{{tp|p=32335749|t=ä. How Could This Happen?: Narrowing Down the Contagion of COVID-19 and Preventing Acute Respiratory Distress Syndrome (ARDS) |pdf=|usr=}}
+
reflected by this or the navigation list.
 +
since dynamic modifable tables are hard to implement
 +
in old wikimeda application its on a simple html page
  
== structure covid19==
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__NOTOC__
'''general aspects'''
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{{tp|p=32254054|t=2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191 |pdf=|usr=}}
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{{tp|p=32254048|t=2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191 |pdf=|usr=}}
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'''genomic variablity'''
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*'''[[PreTAGGED urgent papers]]''' top useful papers entered immediately after reading the actual pubmed list.
*[https://www.sciencedirect.com/science/article/pii/S1567134820301829 ...is high]
+
  
'''nucleocapsid protein'''
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*'''[[TRPM7 2024]]''' Magnesium was my needle in the haystack 02/2020 so I will review the most important Magnesium channel here.
{{tp|p=32363136|t=ä. Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites |pdf=|usr=}}
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== Covid19 target binding and uptake ==
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*'''[[Further reading]]'''
  
== Covid19 cytopathic effects ==
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*'''[[Unproven ideas]] the best-of section'''
  
== Covid19 innate sensing ==
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*'''[[Reviews on covid19 disease]]'''
  
== Covid19 local tissue reaction ==
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*'''[[Children with covid19 disease]]''' Infants see Pregnancy
  
*[https://www.cell.com/action/showPdf?pii=S1074-7613%2820%2930183-7 rev. on covid immunology]
+
*'''[[Clinical guidelines and advice]]'''
  
== Covid19 cytokine storm | hemophagocytic lymphohistiocytosis hlh==
+
*'''[[Respiration mgmt]]'''
*[https://www.standard.co.uk/news/uk/children-hyper-inflammatory-disease-coronavirus-a4434636.html on hlh]
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{{tp|p=32267081|t=2020. Continuous Intravenous Anakinra Infusion to Calm the Cytokine Storm in Macrophage Activation Syndrome |pdf=|usr=}}
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{{tp|p=32267072|t=2020. IV anakinra for macrophage activation syndrome may hold lessons for treatment of  cytokine storm in the setting of COVID19 |pdf=|usr=}}
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== Covid19 ARDS ==
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*'''[[Diagnosis (Laboratory)]]'''
  
== pulmonary embolism / coagulation covid19==
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*'''[[Diagnosis (Lung CT, Sonography)]]'''
*[https://townhall.com/tipsheet/leahbarkoukis/2020/05/05/doctors-are-noticing-a-dangerous-phenomenon-even-after-wuhan-coronavirus-symptoms-are-gone-n2568192 thrombotic late reactions]
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*[https://www.welt.de/wissenschaft/video207855067/Obduktionen-Corona-Patienten-sterben-haeufig-an-Blutgerinnseln.html german autopsy data]
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{{tp|p=32331965|t=ä. Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach |pdf=|usr=}}
+
  
== heart covid19==
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*'''[[Diagnosis (other modalities)]]'''
{{tp|p=32310612|t=2020. Cardiac Manifestations Of Coronavirus (COVID-19)|pdf=|usr=}}
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== neurology, ophthalmology, orl covid19 ==
+
----
{{tp|p=32310553|t=2020. Ophthalmic Manifestations Of Coronavirus (COVID-19)|pdf=|usr=}}
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{{tp|p=32119409|t=2020. Neuroanatomy, Nucleus Gustatory|pdf=https://www.ncbi.nlm.nih.gov/books/NBK554522/#article-36422.s6|usr=}}
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{{tp|p=32295727|t=ä. Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report |pdf=|usr=}}
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{{tp|p=32343122|t=2020. Updates on What ACS Reported: Emerging Evidences of COVID-19 with Nervous System  Involvement |pdf=|usr=}}
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{{tp|p=32320211|t=ä. Neurological Insights of COVID-19 Pandemic |pdf=|usr=}}
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{{tp|p=C7160911|t=ä. SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples  Allowing Earlier Virus Detection |pdf=|usr=}}
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{{tp|p=32348111|t=ä. Is the Collapse of the Respiratory Center in the Brain Responsible for Respiratory Breakdown in COVID-19 Patients?|pdf=|usr=}}
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{{tp|p=32167747|t=2020. Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host?Virus Interaction, and Proposed Neurotropic Mechanisms |pdf=|usr=}}
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{{tp|p=32233443|t=2020. Letter to the Editor ...Evidence of the COVID-19 Virus Targeting the CNS... |pdf=|usr=}}
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{{tp|p=32367205|t=ä. SARS-CoV-2 can induce brain and spine demyelinating lesions |pdf=|usr=}}
+
  
== dermatology covid19==
 
{{tp|p=32315073|t=2020. Cutaneous Clinico-Pathological Findings in three COVID-19-Positive Patients Observed in the Metropolitan Area of Milan, Italy |pdf=|usr=}}
 
  
== gastroenterology and hepatology covid19==
+
*'''[[Structure of covid19]]'''
{{tp|p=32291373|t=2020. Gastrointestinal Presentation in COVID-19 in Indonesia: A Case Report |pdf=|usr=}}
+
  
== Covid19 hypoxia tolerance ==
+
*'''[[Target binding and uptake]]'''
*[http://archive.is/VTqtr happy hypoxia experience]
+
  
== Covid19 putative risk factors ==
+
*'''[[Cytopathic effects]]'''
  
*[https://www.boston25news.com/news/health/high-blood-pressure-drugs-cleared-covid/UC5LTCKKKVDETBWKJDZ2P776XY/ ACEI/AT1RA not risky ?]
+
*'''[[Secretion and shedding]]'''
*[https://theconversation.com/we-found-and-tested-47-old-drugs-that-might-treat-the-coronavirus-results-show-promising-leads-and-a-whole-new-way-to-fight-covid-19-136789 dextrometorphan (antitussive compd)]
+
  
 +
*'''[[Innate sensing]]'''
  
== risk populations covid19 ==
+
*'''[[Immunology]]'''
''' Diabetes, Obesity'''
+
{{tp|p=32249357|t=ä. Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic |pdf=|usr=}}
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''' ACEi ARBs'''
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{{tp|p=32363137|t=ä. Anti-RAS drugs and SARS-CoV-2 infection |pdf=|usr=}}
+
  
== Covid19 secretion ==
+
*'''[[Cytokine storm, hemophagocytic lymphohistiocytosis, macrophage activation syndrome]]'''
 +
----
 +
*'''[[Pathobiology]]'''
  
 +
*'''[[Disease Models]]'''
  
 +
*'''[[Similar diseases and pathomechanisms]]'''
 +
----
  
== anything MERS ==
+
*'''[[Early symptoms]]'''
  
== anything SARS ==
+
*'''[[Systemic disease, any manifestations]]'''
  
== anything Influenza ==
+
*'''[[Co-Infection]]'''
  
== anything Influenza 1918 ==
+
*'''[[Pulmonary embolism, coagulation]]'''
*[https://www.history.com/news/spanish-flu-second-wave-resurgence history.com]
+
  
== anything Ebola ==
+
*'''[[Hematology]]'''
  
== Pathobiology Covid19==
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*'''[[Heart]]'''
{{tp|p=32273135|t=ä. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases |pdf=|usr=}}
+
  
== Disease Models Covid19 ==
+
*'''[[Neurology, ophthalmology, orl]]'''
  
== Diagnosing (Virus / Antibodies) Covid19 ==
+
*'''[[Dermatology]]'''
*[https://archive.fo/61OpY on false-positives]
+
*[https://www.aljazeera.com/news/2020/05/tanzania-covid-19-lab-head-suspended-president-questions-data-200505065136872.html on positives in non-vertebrate samples]
+
*[https://www.wsj.com/articles/roche-coronavirus-antibody-test-wins-fda-approval-for-emergency-use-11588505019 antibody test roche]
+
{{tp|p=32293168|t=ä. Rapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal  Swab Specimens Using Field-Effect Transistor-Based Biosensor |pdf=|usr=}}
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{{tp|p=32223179|t=ä. Diagnosing COVID-19: The Disease and Tools for Detection |pdf=|usr=}}
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{{tp|p=32281785|t=ä. Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection |pdf=|usr=}}
+
  
== Diagnosing (Lung CT, Sonography) Covid19 ==
+
*'''[[Gastroenterology, hepatology]]''' and endocrinology and diabetes
{{tp|p=32276754|t=ä. CT Manifestation of COVID-19 Pneumonia; Role of Multiplanar Imaging |pdf=|usr=}}
+
{{tp|p=32204990|t=2020. Imaging Features of Coronavirus disease 2019 (COVID-19): Evaluation on Thin-Section CT |pdf=|usr=}}
+
{{tp|p=32204987|t=2020. Coronavirus Disease (COVID-19): Spectrum of CT Findings and Temporal Progression  of the Disease |pdf=|usr=}}
+
{{tp|p=32335002|t=ä. COVID-19 Evaluation by Low-Dose High Resolution CT Scans Protocol |pdf=|usr=}}
+
{{tp|p=32331965|t=ä. Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach |pdf=|usr=}}
+
{{tp|p=32327295|t=ä. COVID-19 or Pulmonary Contusion? A Diagnostic Dilemma |pdf=|usr=}}
+
{{tp|p=32312654|t=ä. COVID-19 Pulmonary Involvement: Is Really an Interstitial Pneumonia?|pdf=|usr=}}
+
{{tp|p=32291374|t=2020. The Importance of Chest CT Scan in COVID-19 |pdf=|usr=}}
+
  
== Clinical Guidelines Covid19 ==
+
*'''[[Kidney, urology]]''' and gynecology/obstetrics
  
== Clinical Trials Covid19 ==
+
*'''[[Risk and special populations]]'''
  
*[https://clinicaltrials.gov/ct2/results?cond=COVID-19 at clinicaltrials.gov 1323 running]
+
*'''[[Case reports]]'''
  
== Candidate Compounds Covid19 ==
+
*'''[[Case series]]'''
  
'''reviews candidate compounds covid19'''
+
*'''[[Registries]]'''
{{tp|p=32226821|t=2020. Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases |pdf=|usr=}}
+
{{tp|p=32292689|t=ä. Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods |pdf=|usr=}}
+
  
 +
*'''[[The morbid survivor]]'''
 +
----
  
'''Hydroxychloroquine''' retarget
 
*check retina status known toxicity
 
*[https://justthenews.com/politics-policy/coronavirus/doctors-find-hydroxychloroquin-success-rate-91-urge-arizona-maybe-make 91% benefit]
 
*[https://www.themoscowtimes.com/2020/04/17/russia-approves-unproven-malaria-drug-to-treat-coronavirus-a70025 approval russia]
 
*[https://m.timesofindia.com/business/india-business/covid-19-68-new-companies-get-fdca-permit-to-make-hcq/amp_articleshow/75566317.cms scale up production]
 
*[https://www.medrxiv.org/content/10.1101/2020.04.26.20081059v1.full.pdf+html on safety, trial]
 
  
 +
*'''[[Trials]]'''
  
'''Chlorpromazine''' retarget
+
*'''[[Candidate Compounds Covid19]]'''
*[https://www.biorxiv.org/content/10.1101/2020.05.05.079608v1 paper]
+
----
  
'''Zinc''' add-on
 
*[https://www.sciencedirect.com/science/article/pii/S0306987720306435 call for trial]
 
  
'''Remdesivir''' retarget
+
*'''[[Remission, recurrence and persistence]]'''
*[https://gab.com/Remnant601/posts/104122987152232660 one hospital on...]
+
  
'''Lauric acid''' nat. compd.
+
*'''[[Other routes of infection]]'''
*[https://www.icp.org.ph/2020/01/the-potential-of-coconut-oil-and-its-derivatives-as-effective-and-safe-antiviral-agents-against-the-novel-coronavirus-ncov-2019/ call for trial]
+
  
'''Nicotine''' nat. toxin
+
*'''[[Biophysics of aerosols]]'''
*[https://www.usatoday.com/story/news/factcheck/2020/05/03/covid-19-fact-check-caution-urged-study-virus-smoking/3055378001/ france]
+
  
'''Niclosamide'''
+
*'''[[Passive protective equipment]]'''
{{tp|p=32125140|t=ä. Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential |pdf=|usr=}}
+
  
'''Microbiome as target'''
+
*'''[[Running your hospital]]'''
{{tp|p=32356654|t=ä. Considering the Effects of Microbiome and Diet on SARS-CoV-2 Infection: Nanotechnology Roles |pdf=|usr=}}
+
----
 +
*'''new umbrella page [[Politics main page]]'''
  
'''ACE2 as target'''
+
*'''[[Mental aspects of health professionals]]'''
{{tp|p=32286790|t=ä. Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2 |pdf=|usr=}}
+
  
'''Garlic extracts'''
+
*'''[[Socio-psychiatric aspects of the status hygienicus]]'''
{{tp|p=32363255|t=ä. Investigation into SARS-CoV-2 Resistance of Compounds in Garlic Essential Oil |pdf=|usr=}}
+
  
'''Various Leads'''
+
*''[[Avoiding clinical medicine in other diseases]]''
*[https://theconversation.com/we-found-and-tested-47-old-drugs-that-might-treat-the-coronavirus-results-show-promising-leads-and-a-whole-new-way-to-fight-covid-19-136789 9 retargeted: ternatin4, zotatifin, plitidepsin; haloperidol, melperone, clemastine, cloperastine, pb28, progesterone]
+
*[https://doi.org/10.1038/s41586-020-2286-9 paper in nature]
+
  
== hope: Vaccination Covid19 ==
+
*''[[Occupational medicine, workplace security and status hygienicus]]''
  
*[https://patch.com/massachusetts/cambridge/ma-company-takes-critical-step-toward-covid-19-vaccine mrna-1273, moderna]
+
*''[[Economic aspects of the status hygienicus]]''
  
== hope: Therapeutic antibodies ==
+
*''[[Educational aspects of the status hygienicus]]''
*[https://www.foxnews.com/science/man-made-antibody-neutralizes-coronavirus-first-time anti covid mab]
+
----
*[https://www.telegraaf.nl/nieuws/750205601/nederlands-antilichaam-47-d11-blokkeert-infectie-coronavirus acmab 47d11]
+
  
== hope: Chemoprevention Covid19 ==
 
  
== hope: Antiviral agents Covid19 ==
+
*'''[[Origin of Covid19]]'''
  
== hope: Lung regeneration and repair after Covid19 ==
+
*'''[[Host, vector, one health, atmospheric aspects]]'''
  
== hope: Neurology rehab ==
+
*'''[[Epidemiology]]'''
  
== Remission & Recurrence ==
+
*''[[Failure of politics and public health guidance]]''
*[https://www.livemint.com/news/india/coronavirus-5-to-15-of-covid-19-patients-fall-sick-again-says-china-study-11588855774537.html 10% recurrence rate]
+
  
== Risk group : Nursing home inmates==
+
*''[[Failure of executive measures]]''
*[https://justthenews.com/politics-policy/coronavirus/doctors-find-hydroxychloroquin-success-rate-91-urge-arizona-maybe-make no sunlight no vitamin d]
+
----
  
  
 +
*''[[Political abuse of Covid19]]''
  
== Socio-psychiatric aspects of the status hygienicus ==
+
*''[[Lost people]]''
  
== Economic aspects of the status hygienicus ==
+
*'''[[History of covid19 exploration]]'''
 +
-----
  
== Educational aspects of the status hygienicus ==
+
*'''[[misc.]]'''
  
== Safer Work and status hygienicus ==
+
*'''[[Research tools]]'''
  
jail, abattoirs... crowded indoor places...
+
*'''[[from the ads]]'''
  
== Biophysics of aerosols ==
+
*'''[[Current state of coviki.org]]'''
  
== Aerosolic infection prevention ==
+
{{Searchtermcov}}
 
+
== Other routes of infection ==
+
 
+
*[https://www.dailymail.co.uk/news/article-8296937/Coronavirus-semen-study-shows.html semen]
+
 
+
== passive protective devices ==
+
'''masks'''
+
{{tp|p=32329337|t=ä. Aerosol Filtration Efficiency of Common Fabrics Used in Respiratory Cloth Masks |pdf=|usr=}}
+
{{tp|p=32368894|t=ä. Can N95 Respirators Be Reused after Disinfection? How Many Times?|pdf=|usr=}}
+
 
+
== Running your hospital ==
+
 
+
 
+
{{tp|p=32335003|t=ä. Proposed imaging guidelines for pregnant women suspected of having COVID-19 |pdf=|usr=}}
+
 
+
 
+
'''Diagnostic and Interv. Radiology'''
+
{{tp|p=32303440|t=2020. Radiology Management and COVID-19 in Resource Limited Setting |pdf=|usr=}}
+
{{tp|p=32336647|t=ä. COVID-19 Protection Guidelines in Outpatient Medical Imaging Centers |pdf=|usr=}}
+
{{tp|p=32113880|t=ä. Corona Virus International Public Health Emergencies: Implications for Radiology  Management |pdf=|usr=}}
+
 
+
 
+
'''Hemonc, Radiotherapy, BMT'''
+
{{tp|p=32375142|t=2020. Perspective: SARS-CoV-2, COVID-19 and Haematologists |pdf=|usr=}}
+
 
+
'''Neurosurgery, ORL surgery'''
+
{{tp|p=32222820|t=ä. Neurosurgery during the COVID-19 pandemic: update from Lombardy, northern Italy |pdf=|usr=}}
+
{{tp|p=32314059|t=ä. The impact of COVID-19 on neurosurgeons and the strategy for triaging non-emergent operations: a global neurosurgery study |pdf=|usr=}}
+
{{tp|p=32291593|t=ä. Our darkest hours (being neurosurgeons during the COVID-19 war) |pdf=|usr=}}
+
{{tp|p=32271745|t=2020. Surgical management of head and neck tumours during the SARS-CoV (Covid-19) pandemic |pdf=|usr=}}
+
 
+
== Host, Vector, One Health aspects of Covid19 ==
+
 
+
== Tracing the Origin of Covid19 ==
+
 
+
== Mass Psychology of Covid19 ==
+
*[https://gab.com/1001cutz/posts/104129141050204606 positives bannend from military]
+
 
+
'''social deprivation, suicide'''
+
*[https://www.breitbart.com/health/2020/05/07/report-suicide-rise-from-lockdowns-to-kill-more-than-coronavirus-in-australia/ inc suicide]
+
 
+
== Getting Criminal ==
+
*[https://www.nbcphiladelphia.com/news/coronavirus/researcher-on-verge-of-making-very-significant-virus-findings-shot-to-death/2386375/ reasearcher killed]
+
 
+
== Transformation of the World accepting and abusing the Virus Thread ==
+
 
+
== After civilization breakdown ==
+
*[https://www.elizabethblog.com.ng/2020/05/were-facing-double-pandemic-un-body.html famine]
+
 
+
== KIA ==
+
*[https://www.breitbart.com/politics/2020/05/04/colorado-medic-assist-nyc-dies-coronavirus/ Paul Cary]
+
 
+
== various topics ==
+
{{tp|p=32227916|t=ä. Nano Research for COVID-19 |pdf=|usr=}}
+
 
+
== various case reports covid19==
+
{{tp|p=32291376|t=2020. Clinical Progression of COVID-19 Patient with Extended Incubation Period, Delayed RT-PCR Time-to-positivity, and Potential Role of Chest CT-scan |pdf=|usr=}}
+
 
+
== history of covid19 exploration ==
+
{{tp|p=32291365|t=2020. Diagnosing COVID-19: Did We Miss Anything?|pdf=|usr=}}
+

Aktuelle Version vom 22. Januar 2024, 10:35 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.


32399342 2020. A Case of a COVID-19-positive Patient.

DISCLAIMER the current scientific record is full of falsified and invented data and subject to political abuse. I cannot keep up with the daily retractions, so do not apply any thesis or hypothesis shown here as a valid option for application to human beings.

visit this websites homepage to get 
an expert 3d view on the topics as i assorted them retrospectively
the 3fold separation of the clinical issues is not well 
reflected by this or the navigation list.
since dynamic modifable tables are hard to implement
in old wikimeda application its on a simple html page


  • TRPM7 2024 Magnesium was my needle in the haystack 02/2020 so I will review the most important Magnesium channel here.














search for covid papers via moremed.org: bc illicit search term expansion with neglect of "" function by pubmed, 2019-ncov OR 2019ncov has to be eliminated from the search term since dec /2021


  • ("mg2+" OR "mg(2+)" OR magnesium OR hypomagnesi* OR hypermagnesi* OR mgcl2 OR trpm7 OR ltrpc7 OR trp-plik OR trpm6 OR transient receptor potential m7 OR transient receptor potential m6 OR chanzyme OR arl15 OR magt1 OR cnnm1 OR cnnm2 OR acdp1 OR acdp2 OR cnnm3 OR cnnm4 OR cyclin-m1 OR cyclin-m2 OR cyclin-m3 OR cyclin-m4 OR "cyclin m1" OR "cyclin m2" OR "cyclin m3" OR "cyclin m4" OR slc41a1 OR slc41a2 OR slc41a3 OR mgte OR solute carrier protein 41 OR nipa1 OR spg6 OR nipa2 OR huntingtin1 OR hip14 OR hip14l OR prl-1 OR prl-2 OR prl-3 OR ptp4a1 OR ptp4a2 OR ptp4a3 OR micu-1 OR micu-2 OR "micu 1" OR "micu 2" OR paracellin-1 OR claudin-16 OR pcln-1 OR claudin-19 OR mmgt1 OR mmgt2 OR alr1 OR alr2 OR mrs2 OR atmrs2 OR lpe10 ) filter any magnesium. enhanced from two tables of


18927203 The unique nature of mg2+ channels.
21640700 Cellular magnesium homeostasis. ---

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