Candidate Compounds Covid19

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  '''CHERRYPICKING STUDIES IS NOT SCIENCE
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{{qt|Reviews on covid drug development}}
  
current items will be put into the subsections.
 
  
*[[reviews on covid drug development]]
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*'''[[scouting ideas]]'''
*[[scouting ideas]]
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*[[Patients on biologicals]]
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*'''[[PHA Biologicals]]'''
*[[HMGB1, RAGE]]
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*[[pre-Interleukin 6]]
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*[[post-Interleukin 6]]
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*[[pre-TNFalpha]]
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*[[post-TNFalpha]]
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*[[pre-Interleukin 17]]
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*[[post-Interleukin 17]]
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*[[pre-Interleukin 1]]
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*[[post-Interleukin 1]]
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*[[Inflammasome]] ''colchicine''
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*[[other anti-inflammatory]]
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*[[NK-kappaB]]
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*[[STAT 3]]
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*[[JAK Janus Kinase]]
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*[[Corticosteroids]]
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*[[Cytokine absorbers]]
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*[[Target Complement system]]
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*[[Target Extracellular traps]]
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*[[Anticoagulant in covid19]]
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*[[Antioxidants]]
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*[[Stem cells]]
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*[[MDSC cells]]
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*[[Interferons]]
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*'''[[PHA conventional pharmacology]]'''
  
*[[other single compounds]]
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*'''[[PHA retargeted compounds]]'''
*[[Retargeted single compounds]]
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*[[Hydroxychloroquine]]
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*
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*[[Target ACE2, Spike protein]]
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*[[Target TMPRSS2, Spike protein]] ''any other covid targed herein''
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*[[other antiviral compounds]]
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*[[AV Remdesivir]]
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*[[AV Lopinavir]]
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*[[AV Ivermectin]]
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*'''[[PHA antivirals by mechanism]]'''
  
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*'''[[PHA pharmacophore by screened target]]'''
  
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*'''[[PHA ImmunoNutrients]]
  
*[[Vitamin D]]
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*'''[[PHA compl altern natural]]'''
*[[Anorganic nutrients Magnesium]]
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*[[Anorganic nutrients Selenium]]
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*[[Anorganic nutrients Zinc]]
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*[[Nutrition, general]]
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*[[Exercise, Vibration]]
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*'''[[PHA within indications compounds]]'''
  
*[[Traditional Chinese Medicine]]
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*'''[[PHA Serum products]]'''
*[[Natural compounds]]
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*[[Statins]]
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*'''[[PHA Vaccination]]'''
*[[Antidiabetic compounds, any]]
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*[[RSP - On RAS drugs]]
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*[[Reconvalescent blood products, Passive vaccine]]
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PHA related options:
*[[Plasmapheresis]]
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*[[Immunodeviation]] e.g. by adjuvants or other vaccinations
 
 
*[[Radiation therapy]]
 
*[[Radiation therapy]]
 
*[[Phototherapy]]
 
*[[Phototherapy]]
*[[Active vaccine]]  
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*[[Electric fields]]
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*[[Treatment other concepts]]
  
  
-rest-
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A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
{{tp|p=32229705|t=2020. Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections |pdf=|usr=}}
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This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
{{tp|p=32276453|t=2020. Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency  and Similar Future Global Health Threats |pdf=|usr=}}
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vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
{{tp|p=32325124|t=ä. Vaporization, bioactive formulations and a marine natural product: different perspectives on antivirals |pdf=|usr=}}
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Paper is (not yet in PubMed) :
{{tp|p=32312129|t=2020. The role of additive manufacturing and antimicrobial polymers in the COVID-19 pandemic |pdf=|usr=}}
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{{tp|p=32336674|t=ä. COVID-19 Emergency Responders in FDA?s Center for Drug Evaluation and Research |pdf=|usr=}}
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*'''[https://www.sciencedirect.com/science/article/pii/S1097276520305499?via%3Dihub Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication at Mol Cell 2020/08/11]'''
{{tp|p=32356251|t=ä. Medical Toxicology and COVID-19: Our Role in a Pandemic |pdf=|usr=}}
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credentials to [https://web.de/magazine/news/coronavirus/coronavirus-blockade-zellulaerer-kommunikation-forscher-stoppen-vermehrung-sars-cov-2-35045170 Marinus Brandl] who told us about it today.
{{tp|p=32243778|t=2020. Ensuring global access to COVID-19 vaccines |pdf=|usr=}}
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based on e.g.
{{tp|p=32247324|t=2020. Global coalition to accelerate COVID-19 clinical research in resource-limited settings |pdf=|usr=}}
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{{tp|p=32272857|t=2020. Role of Tissue Engineering in COVID-19 and Future Viral Outbreaks |pdf=|usr=}}
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{{ttp|p=32408336|t=2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets |pdf=|usr=}}
{{tp|p=C7190525|t=2020. Adjunct Immunotherapies for the Management of Severely Ill COVID-19 Patients |pdf=|usr=}}
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{{tp|p=32129977|t=2020. Cell-Membrane-Mimicking Nanodecoys against Infectious Diseases |pdf=|usr=}}
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=======================================================================================
{{tp|p=29115746|t=2018. Progress Toward the Clinical Translation of Bioinspired Peptide and Protein Assemblies |pdf=|usr=}}
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{{tp|p=29717819|t=2018. Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens |pdf=|usr=}}
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COVID19 is now a CURABLE disease !!!
{{tp|p=C7194243|t=ä. Coronavirus Disease 2019 (COVID-19) Spread and Pharmacovigilance Implications: Expert Opinion |pdf=|usr=}}
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{{tp|p=32383008|t=ä. The Role of Pharmacovigilance and ISoP During the Global COVID-19 Pandemic |pdf=|usr=}}
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=======================================================================================
{{tp|p=32380052|t=2020. Granulocyte-targeted therapies for airway diseases |pdf=|usr=}}
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{{tp|p=32452420|t=2020. Antiviral activity of lycorine against Zika virus in vivo and in vitro |pdf=|usr=}}
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Aktuelle Version vom 21. September 2021, 06:15 Uhr

homepage
hottest actual papers
 P further streaming-in related content is here
 CHERRYPICKING STUDIES IS NOT SCIENCE
Reviews on covid drug development


PHA related options:


A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
Paper is (not yet in PubMed) :

credentials to Marinus Brandl who told us about it today. based on e.g.

32408336 2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
=======================================================================================
COVID19 is now a CURABLE disease !!!
=======================================================================================

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