Active vaccine

Aktuelle Version vom 17. Januar 2021, 09:15 Uhr

• [RadVac intranasal chitosan based conventional vaccine development consortium ISO industry support]

32105090 2020. Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic

• mrna-1273, moderna

32183941 2020. A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2
32298218 2020. Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19
32209231 2020. Computers and viral diseases Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-CoV-2 (2019-nCoV, COVID-19) coronavirus
32219057 ä. The SARS-CoV-2 Vaccine Pipeline: an Overview
32148172 2020. Timely development of vaccines against SARS-CoV-2
32269766 2020. In silico identification of vaccine targets for 2019-nCoV
32265848 2020. Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses
32300370 2020. Can an effective SARS-CoV-2 vaccine be developed for the older population?
32259480 ä. SARS-CoV-2 Vaccines: Status Report
32291382 2020. Coronavirus Vaccines: Light at the End of the Tunnel
32352026 2020. Epitope based vaccine prediction for SARS-COV-2 by deploying immuno-informatics approach
32295479 2020. Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study
32372051 ä. Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2
32335161 ä. In the search of potential epitopes for Wuhan seafood market pneumonia virus using high order nullomers
32232474 ä. Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure

• Oxford vaccine failed in monkeys

32348489 ä. COVID-19: Is Everything Appropriate to Create an Effective Vaccine?
32328406 ä. Vaccines for SARS-CoV-2: Lessons from Other Coronavirus Strains
32022276 2020. Immunoinformatics?aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019?nCoV
32249203 ä. Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

• Nature: The COVID-19 vaccine development landscape

32353328 2020. What policy makers need to know about COVID-19 protective immunity
32171450 2020. Identification of potential cross-protective epitope between a new type of coronavirus (2019-nCoV) and severe acute respiratory syndrome virus
32265331 2020. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection
32355330 ä. Inactivated vaccine for SARS-CoV-2
32289117 2020. Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus
32346092 ä. Cancer therapy tool informs COVID-19 vaccines
32194995 2020. The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines
32229574 2020. News Feature: Avoiding pitfalls in the pursuit of a COVID-19 vaccine
32347054 2020. Strategies for vaccine development of COVID-19
32304139 ä. Progress and Concept for COVID?19 Vaccine Development
32295153 2020. What Does Plant-Based Vaccine Technology Offer to the Fight against COVID-19?
32235387 2020. Progress and Prospects on Vaccine Development against SARS-CoV-2
32106567 2020. Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies
32249063 ä. Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses
32362491 ä. Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses: (Trends in Immunology 41, 355?359; 2020)
32340998 2020. Covid-19: What do we know so far about a vaccine?
32366511 2020. Developing a vaccine for covid-19
32379348 2020. 3CL hydrolase-based multiepitope peptide vaccine against SARS-CoV-2 using immunoinformatics
32320059 2020. Potential of live pathogen vaccines for defeating the COVID-19 pandemic: history and mechanism
32285942 2020. Defining Protective Epitopes for COVID-19 Vaccination Models
32375002 ä. Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery
32366816 2020. An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development
32376359 ä. Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2
32355243 2020. Scores of coronavirus vaccines are in competition - how will scientists choose the best?
32227757 2020. Developing Covid-19 Vaccines at Pandemic Speed
32234130 2020. Progress and challenge of vaccine development against 2019 novel coronavirus (2019-nCoV)
32245869 2020. Possible treatment of Covid-19 with a therapeutic vaccine
32221001 2020. Possible method for the production of a Covid-19 vaccine
32301312 2020. Vaccins anti-covid-19 : les recherches de johnson & johnson, sanofi et pasteur
32355008 2020. COVID-19 shot protects monkeys
32300225 2020. On the front lines of the coronavirus-vaccine battle
32346146 2020. The race for coronavirus vaccines: a graphical guide
32376603 ä. Development of an inactivated vaccine candidate for SARS-CoV-2
32377399 2020. COVID-19 vaccines: breaking record times to first-in-human trials
C7152890 2020. Biomimetic nanoparticles as universal influenza vaccine

• Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus btu @OnlyTheGhosts

30993690 2019. Emerging viruses and current strategies for vaccine intervention
32259744 2020. DNA vaccines: prime time is now
32387642 2020. Innovations in structure-based antigen design and immune monitoring for next generation vaccines
32344202 2020. Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development
32318055 2020. Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools
16022774 2005. (+)SARS Vaccine Development
28861908 2017. (+)Issues in vaccinology: Present challenges and future directions
C7202844 ä. (+)Vaccine development during global epidemics: the Zika experience

31351923 2019. (+)First clinical trial of a MERS coronavirus DNA vaccine
16697221 2006. (+)Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus
29852530 2020. The expanding role of mass spectrometry in the field of vaccine development
32325038 ä. (+)Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial
31692019 2020. (+)Gold nanoparticle?adjuvanted S protein induces a strong antigen?specific IgG response against severe acute respiratory syndrome?related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs
32377399 2020. COVID-19 vaccines: breaking record times to first-in-human trials
32376359 2020. Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2
32418793 2020. An effective CTL peptide vaccine for Ebola Zaire Based on Survivors? CD8+ targeting of a particular nucleocapsid protein epitope with potential implications for COVID-19 vaccine design
32381478 2020. Enabling emergency mass vaccination: Innovations in manufacturing and administration during a pandemic
32483236 2020. Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients.
32471334 2020. Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV.
32437478 2020. Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2.
32463026 2020. A Novel Vaccine Employing Non-Replicating Rabies Virus Expressing Chimeric SARS-CoV-2 Spike Protein Domains: Functional Inhibition of Viral/Nicotinic Acetylcholine Receptor Complexes.
32498742 2020. SARS-CoV-2 (COVID-19) Vaccine Development and Production: An Ethical Way Forward.
32555466 2020. COVIDep: a web-based platform for real-time reporting of vaccine target recommendations for SARS-CoV-2.
32497168 2020. On setting expectations for a SARS-CoV-2 Vaccine.
32492123 2020. The Importance of Advancing SARS-CoV-2 Vaccines in Children.

32393526 2020. A strategic approach to COVID-19 vaccine R&D.
32385100 2020. Rapid COVID-19 vaccine development.

32527802 2020. The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients.
32132669 ä. Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS-CoV-2 compared to SARS-CoV
32380868 2020. Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?
32442040 2020. SARS-CoV-2, from its current highly contagious spreading toward the global development of an effective and safe vaccine: challenges and uncertainties.
32419646 2020. Design of multi-epitope vaccine candidate against SARS-CoV-2: a in-silico study.
32437587 2020. COVID-19 vaccines: knowing the unknown.
32460358 2020. The early landscape of COVID-19 vaccine development in the UK and rest of the world.
32441894 2020. Why Challenge Trials of SARS-CoV-2 Vaccines Could Be Ethical Despite Risk of Severe Adverse Events.
32427644 2020. Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines: Setting Expectations Appropriately.
32203367 2020. Coronavirus vaccines: five key questions as trials begin.
32472069 2020. Questions remain following first COVID-19 vaccine results.
32273621 2020. If a coronavirus vaccine arrives, can the world make enough?
32473352 2020. Understanding the B and T cell epitopes of spike protein of severe acute respiratory syndrome coronavirus-2: A computational way to predict the immunogens.
32485211 2020. Advances in skin science enable the development of a COVID-19 Vaccine.
32499988 2020. Protective Adaptive Immunity Against Severe Acute Respiratory Syndrome Coronaviruses 2 (SARS-CoV-2) and Implications for Vaccines.
32505245 2020. COVID-19 vaccine development pipeline gears up.
32496238 2020. COVID-19 vaccine development and the way forward.
32325036 ä. (+)Two Middle East respiratory syndrome vaccines: first step for other coronavirus vaccines?
32397182 2020. (+)Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development.
32386655 2020. Influence of immune aging on vaccine responses
32497149 2020. In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction.
32517882 2020. Immunoinformatics-guided designing of epitope-based subunit vaccines against the SARS Coronavirus-2 (SARS-CoV-2).
32405164 2020. 2019-nCoV - Towards a 4th generation vaccine.
32525830 2020. A vaccine is not too far for COVID-19.
32365191 2020. Balancing Expediency and Scientific Rigor in SARS-CoV-2 Vaccine Development.
32108359 2020. Development of epitope-based peptide vaccine against novel coronavirus 2019 (SARS-COV-2): Immunoinformatics approach.
32516041 2020. The quest to find an effective vaccine for COVID-19.
32451112 2020. Race for a COVID-19 vaccine.
32404020 2020. COVID-19: The race for a vaccine.
32514102 2020. COVID-19 vaccines start moving into advanced trials.
32454128 2020. Design of a Novel Multi Epitope-Based Vaccine for Pandemic Coronavirus Disease (COVID-19) by Vaccinomics and Probable Prevention Strategy against Avenging Zoonotics.
32417398 2020. High throughput and comprehensive approach to develop multiepitope vaccine against minacious COVID-19.
32493510 2020. SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines.
32409451 2020. U.S. 'Warp Speed' vaccine effort comes out of the shadows.
32535078 2020. Vaccination strategies to combat novel corona virus SARS-CoV-2.
32450054 2020. Hydroxychloroquine prophylaxis for high-risk COVID-19 contacts in India: a prudent approach.
32473139 2020. Death threats after a trial on chloroquine for COVID-19.
32518920 2020. Caution and clarity required in the use of chloroquine for COVID-19.
32473680 2020. The starting line for COVID-19 vaccine development.
32450106 2020. Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial.
32437926 2020. From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development.
32533920 2020. The Improbability of the Rapid Development of a Vaccine for SARS-CoV-2.
32499636 2020. COVID-19 vaccines: neutralizing antibodies and the alum advantage.
32433465 2020. Immunogenicity of a DNA vaccine candidate for COVID-19. }}
32528732 2020. Universal coronavirus vaccines: the time to start is now.
32509338 2020. Certainty of success: three critical parameters in coronavirus vaccine development.
32456404 2020. The vaccine journey for COVID-19: a comprehensive systematic review of current clinical trials in humans.

32387011 2020. Tortoises, hares, and vaccines: A cautionary note for SARS-CoV-2 vaccine development.
32418794 2020. A Veterinary Vaccine Development Process Map to assist in the development of new vaccines.
32526960 2020. Immunoinformatics and Structural Analysis for Identification of Immunodominant Epitopes in SARS-CoV-2 as Potential Vaccine Targets.
32531955 2020. Prospects of Replication-Deficient Adenovirus Based Vaccine Development against SARS-CoV-2.
32513867 2020. Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits.
32434945 2020. DNA vaccine protection against SARS-CoV-2 in rhesus macaques.

32548679 2020. Calling for an exponential escalation scheme in vaccine development for COVID-19.
32591957 2020. Once we have it, will we use it? A European survey on willingness to be vaccinated against COVID-19.
32543297 2020. Why do SARS-COV vaccines not exist? The pharma scientific intelligence and business model must be revisited!
32557648 2020. Vaccine development and therapeutic design for 2019-nCoV/SARS-CoV-2: Challenges and chances.
32565096 2020. Anticipating SARS-CoV-2 Vaccine Testing, Licensure, and Recommendations for Use.
32591466 2020. SARS-CoV-2 vaccines: 'Warp Speed' needs mind melds not warped minds.
32572246 2020. Preclinical data from SARS-CoV-2 mRNA vaccine.
32559452 2020. Hydroxychloroquine use in COVID-19: what is the basis for baseline tests?
32555401 2020. Optimizing safety surveillance for COVID-19 vaccines.
32592866 2020. Emerging vaccine delivery systems for COVID-19: Functionalised silica nanoparticles offer a potentially safe and effective alternative delivery system for DNA/RNA vaccines and may be useful in the hunt for a COVID-19 vaccine.
32591367 2020. Is the production of a Covid-19 vaccine using transformed Pasteurella plausible?
32461973 2020. Design of a Multiepitope-Based Peptide Vaccine against the E Protein of Human COVID-19: An Immunoinformatics Approach.
32557771 2020. How to expedite early-phase SARS-CoV-2 vaccine trials in pandemic setting-A practical perspective.

32407708 2020. The Challenges of Vaccine Development against a New Virus during a Pandemic.
32407707 2020. Rational Vaccine Design in the Time of COVID-19.

32596085 2020. Acute Respiratory Failure Secondary to COVID-19 Viral Pneumonia Managed With Hydroxychloroquine/Azithromycin Treatment.
32546606 2020. The Nucleocapsid Protein of SARS-CoV-2: a Target for Vaccine Development.
32447675 2020. "Es wird mehrere Pandemie-Impfstoffe geben" : SARS-CoV-2 / COVID-19.
32291653 2020. Vielversprechender Impfstoffkandidat gegen COVID-19 identifiziert.
32547625 2020. The journey of remdesivir: from Ebola to COVID-19.
32597077 2020. [Progress and analysis on the development of 2019-nCoV vaccine].

32433634 2020. Coronavirus vaccine trials have delivered their first results - but their promise is still unclear.
32576992 2020. Latin American scientists join the coronavirus vaccine race: 'No one's coming to rescue us'.
32600777 2020. Working Hard or Hardly Working? Regulatory Bottlenecks in Developing a COVID-19 Vaccine.
32600910 2020. Logistical challenges for potential SARS-CoV-2 vaccine and a call to research institutions, developers and manufacturers.
32600909 2020. Allocation criteria for an initial shortage of a future SARS-CoV-2 vaccine and necessary measures for global immunity.
32600911 2020. Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality.
32600908 2020. Emerging manufacturers engagements in the COVID -19 vaccine research, development and supply.
32525587 2020. Potential for elimination of SAR-CoV-2 through vaccination as inspired by elimination of multiple influenza viruses through natural pandemics or mass vaccination.
32609415 2020. SARS-CoV-2 vaccination-A plea for fast and coordinated action.
32566261 2020. Applying lessons from the Ebola vaccine experience for SARS-CoV-2 and other epidemic pathogens.
32553431 2020. Are Genetic Vaccines the Right Weapon against COVID-19?

32540271 2020. COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies?
32595358 2020. An insight into the epitope-based peptide vaccine design strategy and studies against COVID-19.
32583729 2020. Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine.