Structure of covid19
coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.
integrative papers
32507543 2020. Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2.
32181901 ä. A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019?nCoV)
32296735 2020. Prudently conduct the engineering and synthesis of the SARS-CoV-2 virus
C7085496 ä. Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV)
32254054 2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191
32254048 2020. Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191
32311462 2020. On the molecular determinants of the SARS-CoV-2 attack
32229288 ä. Molecular characterization of SARS-CoV-2 from the first case of COVID-19 in Italy
32306836 2020. Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
32265180 ä. Genotype and phenotype of COVID-19: Their roles in pathogenesis
32178970 2020. Composition of human-specific slow codons and slow di-codons in SARS-CoV and 2019-nCoV are lower than other coronaviruses suggesting a faster protein synthesis rate of SARS-CoV and 2019-nCoV
32350227 2020. Characteristics of SARS-CoV-2 isolated from asymptomatic carrier in Tokyo
32342926 2020. Properties of Coronavirus and SARS-CoV-2
32194253 ä. Molecular basis of COVID-19 relationships in different species: a one health perspective
32303698 ä. A map of SARS-CoV-2 and host cell interactions
C7085496 ä. Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV)
32218151 2020. Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins
32098422 2020. Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV
32348474 2020. Expanding our understanding of the role polyprotein conformation plays in the coronavirus life cycle
32367648 2020. SARS-CoV-2 variants: Relevance for symptom granularity, epidemiology, immunity (herd, vaccines), virus origin and containment?
32342578 2020. The Importance Of Naturally Attenuated Sars-Cov-2 In The Fight Against Covid-19
32104911 ä. Evolutionary history, potential intermediate animal host, and cross?species analyses of SARS?CoV?2
32365353 2020. Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform
32092385 2020. The continuous evolution and dissemination of 2019 novel human coronavirus
32361530 2020. The puzzle of sharing bio-molecular targets between coronaviruses and mediators of the cardiovascular system in humans: Looking for plausible hypotheses
32402329 2020. Novel human coronavirus (SARS-CoV-2): A lesson from animal coronaviruses
32452417 2020. New insights into the evolutionary features of viral overlapping genes by discriminant analysis
| 31916022 2020. Cryo-EM Studies of Virus-Antibody Immune Complexes |
genome
- Genome announcements pure genome data without specific hypothesis
- Interkingdom homologies
32398273 2020. RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses: a first look.
32330414 ä. The Architecture of SARS-CoV-2 Transcriptome
32289263 ä. An Infectious cDNA Clone of SARS-CoV-2
| 32341946 2020. Chaos game representation dataset of SARS-CoV-2 genome |
C7200767 2020. Chaos game representation dataset of SARS-CoV-2 genome
32301390 2020. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction
32167166 ä. An exclusive 42 amino acid signature in pp1ab protein provides insights into the evolutive history of the 2019 novel human?pathogenic coronavirus (SARS?CoV?2)
32145215 ä. Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2
32471829 2020. Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis of SARS-CoV-2-Related Viruses.
32437232 2020. Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19.
32422894 2020. A Novel Synonymous Mutation of SARS-CoV-2: Is This Possible to Affect Their Antigenicity and Immunogenicity?
| 32484220 2020. Discovery of G-quadruplex-forming sequences in SARS-CoV-2. |
32472763 2020. Comparative analysis of Coronaviridae nucleocapsid and surface glycoprotein sequences.
32503822 2020. Human Gene Sequences in SARS-CoV-2 and Other Viruses.
32503821 2020. SARS-CoV-2 orf1b Gene Sequence in the NTNG1 Gene on Human Chromosome 1.
32474553 2020. Analysis of RNA sequences of 3636 SARS-CoV-2 collected from 55 countries reveals selective sweep of one virus type.
32492196 2020. High-Coverage SARS-CoV-2 Genome Sequences Acquired by Target Capture Sequencing.
32492183 2020. Evidence for mutations in SARS-CoV-2 Italian isolates potentially affecting virus transmission.
| 32420944 2020. The impact of MicroRNAs (miRNAs) on the genotype of coronaviruses. |
| 32425659 2020. Investigating the genomic landscape of novel coronavirus (2019-nCoV) to identify non-synonymous mutations for use in diagnosis and drug design. |
| 32522874 2020. Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses. |
32416074 2020. A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein.
32525765 2020. Genetic cluster analysis of SARS-CoV-2 and the identification of those responsible for the major outbreaks in various countries.
32524946 2020. Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.
| 32522249 2020. Genomics of COVID-19: molecular mechanisms going from susceptibility to severity of the disease. |
32534867 2020. Sequence homology between human PARP14 and the SARS-CoV-2 ADP ribose 1'-phosphatase.
| 32473977 2020. Unfolding SARS-CoV-2 viral genome to understand its gene expression regulation. |
32501423 2020. Developing an ultra-efficient microsatellite discoverer to find structural differences between SARS-CoV-1 and Covid-19.
32159234 2020. Identification of coronavirus sequences in carp cDNA from Wuhan, China.
structure
32092911 2020. Rigidity of the Outer Shell Predicted by a Protein Intrinsic Disorder Model Sheds Light on the COVID-19 (Wuhan-2019-nCoV) Infectivity
32362648 2020. Transmission electron microscopy imaging of SARS-CoV-2
32361692 2020. How the COVID-19 Overcomes the Battle? An Approach to Virus Structure
32292212 2020. Photopolarimetrical properties of coronavirus model particles: Spike proteins number influence
| 32470119 2020. Coronavirus3D: 3D structural visualization of COVID-19 genomic divergence. |
32493627 2020. Structural Proteins in Severe Acute Respiratory Syndrome Coronavirus-2.
nsp
| 32270884 2020. Role of Nonstructural Proteins in the Pathogenesis of SARS-CoV-2 |
32275073 2020. Response to Ribeiro da Silva et al ,"Role of Nonstructural Proteins in the Pathogenesis of SARS-CoV-2
nsp1 protein
32336957 2020. Combination of Biodata Mining and Computational Modelling in Identification and Characterization of ORF1ab Polyprotein of SARS-CoV-2 Isolated from Oronasopharynx of an Iranian Patient
nsp2 protein
32083328 ä. COVID?2019: The role of the nsp2 and nsp3 in its pathogenesis
nsp3 protein
32083328 ä. COVID?2019: The role of the nsp2 and nsp3 in its pathogenesis
29128390 2018. Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
nsp6 protein
32283146 2020. Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy.
nsp15 endoribonuclease NendoU
32304108 2020. Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2
papain-like proteinase 2
32216114 ä. Structural and biochemical characterization of SARS-CoV papain-like protease 2
replication factors
32321524 2020. Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant
32277040 2020. Structure of the RNA-dependent RNA polymerase from COVID-19 virus
32167173 ä. The potential chemical structure of anti?SARS?CoV?2 RNA?dependent RNA polymerase
| 32511245 2020. A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis. |
32438371 2020. Structure of replicating SARS-CoV-2 polymerase.
32443810 2020. A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping.
32427393 2020. Telomeres and COVID-19.
32392072 2020. Novel Coronavirus Polymerase and Nucleotidyl-Transferase Structures: Potential to Target New Outbreaks.
32526208 2020. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
32531208 2020. Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2.
nucleocapsid
32363136 ä. Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites
32302675 ä. Comparative computational analysis of SARS-CoV-2 nucleocapsid protein epitopes in taxonomically related coronaviruses
32416961 2020. Biochemical characterization of SARS-CoV-2 nucleocapsid protein
| 32291557 ä. SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells |
vacuolar interaction
| 32485205 2020. The endosomal lipid bis(monoacylglycero) phosphate as a potential key player in the mechanism of action of chloroquine against SARS-COV-2 and other enveloped viruses hijacking the endocytic pathway. |
innate interference
virus secretion
envelope
receptor binding: trmpss2
32165541 2020. Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
32404436 2020. TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes.
32410502 2020. First comprehensive computational analysis of functional consequences of TMPRSS2 SNPs in susceptibility to SARS-CoV-2 among different populations.
32437018 2020. TMPRSS2: Potential Biomarker for COVID-19 Outcomes.
32468052 2020. Pancancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARSCoV2 infection leading to COVID-19.
receptor binding: trmpss4
32404436 2020. TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes.
receptor binding: grp78, g-proteins
| 32169481 2020. COVID-19 spike-host cell receptor GRP78 binding site prediction |
32329083 2020. (ang.)COVID-19 transmission through host cell directed network of GPCR
candidate receptor binding DPP4
32405622 2020. The MERS-CoV Receptor DPP4 as a Candidate Binding Target of the SARS-CoV-2 Spike.
Uptake: cathepsin L
32468052 2020. Pancancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARSCoV2 infection leading to COVID-19.
endocytosis membrane fusion
32047258 ä. Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
32265513 ä. SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion
32130973 2020. A potential role for integrins in host cell entry by SARS-CoV-2
32246503 ä. SARS?COV?2 and infectivity: Possible increase in infectivity associated to integrin motif expression
32272173 2020. Coronavirus membrane fusion mechanism offers a potential target for antiviral development
32094589 ä. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
| 32376634 2020. Cell entry mechanisms of SARS-CoV-2 |
32047128 2020. Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection
| 32428379 2020. Understanding SARS-CoV-2 endocytosis for COVID-19 drug repurposing. |
32479856 2020. SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention.
3CL proteinase and main proteinase is the same
32293875 ä. Why Are Lopinavir and Ritonavir Effective against the Newly Emerged Coronavirus 2019? Atomistic Insights into the Inhibitory Mechanisms
32239142 ä. Potential covalent drugs targeting the main protease of the SARS-CoV-2 coronavirus
32308266 2020. Molecular docking and dynamics simulation of FDA approved drugs with the main protease from 2019 novel coronavirus
32313296 2020. Identification of potential binders of the main protease 3CLpro of the COVID-19 via structure-based ligand design and molecular modeling
32391184 2020. Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease
32210741 2020. Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target
32194944 2020. Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CL pro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates
orf
32357959 2020. An 81 nucleotide deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020)
32371472 2020. SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis
32433742 2020. Extended ORF8 Gene Region Is Valuable in the Epidemiological Investigation of SARS-similar Coronavirus.
varia
| 32452762 2020. SARS-CoV-2 strategically mimics proteolytic activation of human ENaC. |
32200634 ä. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1
| 32289821 ä. Extreme genomic CpG deficiency in SARS-CoV-2 and evasion of host antiviral defense |
32123347 ä. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
C7152894 ä. A COMPREHENSIVE ANALYSIS OF GENOME COMPOSITION AND CODON USAGE PATTERNS OF EMERGING CORONAVIRUSES
32366025 2020. Codon Usage and Phenotypic Divergences of SARS-CoV-2 Genes
32291894 2020. Cytosine drives evolution of SARS-CoV-2
32159237 ä. From SARS and MERS CoVs to SARS?CoV?2: Moving toward more biased codon usage in viral structural and nonstructural genes
C7181939 2020. Etymologia: Coronavirus
32387562 2020. Coding potential and sequence conservation of SARS-CoV-2 and related animal viruses
32294518 2020. A comprehensive analysis of genome composition and codon usage patterns of emerging coronaviruses
