Pathobiology

Version vom 27. Juni 2020, 09:20 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

• special pattern of pulmonary neoagiogenesis
• doctors youtube on autopsy findings 05/2020

32273135 ä. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases
32275742 ä. COVID-19 Autopsies, Oklahoma, USA
32361635 2020. Analysis of complement deposition and viral RNA in placentas of COVID-19 patients
32163542 ä. Histopathologic Changes and SARS?CoV-2 Immunostaining in the Lung of a Patient With COVID-19
32360606 2020. SARS-CoV2 entry and spread in the lymphatic drainage system of the brain
32353523 ä. SARS-CoV-2: a new virus but a familiar inflammation brain pattern
32370257 2020. Bioenergy Crisis in Coronavirus Diseases?
32375085 ä. Pathophysiological Characteristics and Therapeutic Approaches for Pulmonary Injury and Cardiovascular Complications of Coronavirus Disease 2019
32346074 ä. Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient
32360729 ä. Postmortem Lung Findings in an Asthmatic with Coronavirus Disease 2019 (COVID-19)
32283063 ä. A call to action : the need for autopsies to determine the full extent of organ involvement associated with COVID-19 infections
32334082 ä. ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection
32270184 ä. Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19
32307550 ä. Down-regulated gene expression spectrum and immune responses changed during the disease progression in COVID-19 patients
32207983 2020. Covid-19 infection and mortality: a physiologist?s perspective enlightening clinical features and plausible interventional strategies
32234451 ä. COVID-19, SARS and MERS: are they closely related?

32294179 ä. Coronavirus infections and type 2 diabetes-shared pathways with therapeutic implications
32293672 ä. Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts
32350105 ä. Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection
32341103 2020. Understanding the Renin-Angiotensin-Aldosterone-SARS-CoV-Axis: A Comprehensive Review
32198987 2020. Gross examination report of a COVID-19 death autopsy
32198986 2020. Review and Prospect of Pathological Features of Corona Virus Disease
32198985 2020. Guide to the Forensic Pathology Practice on Death Cases Related to Corona Virus Disease 2019 COVID-19 Trial Draft
32198984 2020. Academician Cong Bin: Autopsy of SARS-CoV-2 infection is needed to be strengthened
32198983 2020. From SARS-CoV to SARS-CoV-2: The response and challenge of forensic infectious disease autopsy
32170560 ä. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection

32317509 2020. COVID-19 and lung pathology
32345362 2020. Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues
32333601 ä. Expression of SARS-CoV-2 Entry Molecules ACE2 and TMPRSS2 in the Gut of Patients With IBD

32094336 2020. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
32283245 ä. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated
32282428 ä. What s Old is New! Similarities Between SARS-CoV-2 and HIV
32303424 ä. Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19
32315733 ä. Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms

32357503 2020. COVID-19 Deaths: Are We Sure It Is Pneumonia? Please, Autopsy, Autopsy, Autopsy!
32244779 2020. Master Regulator Analysis of the SARS-CoV-2/Human Interactome
32366599 2020. SARS-CoV-2 detection in formalin-fixed paraffin-embedded tissue specimens from surgical resection of tongue squamous cell carcinoma

32283163 ä. A potential inhibitory role for integrin in the receptor targeting of SARS-CoV-2
32348495 ä. Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with disease severity in COVID-19
32344401 2020. COVID-19: Possible Impact of the Genetic Background in IFNL Genes on Disease Outcomes
32080991 2020. Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea
32056249 2020. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS?CoV, MERS?CoV, and 2019?nCoV

32340678 2020. Pathology of 2019 Novel Coronavirus Pneumonia: A Dynamic Disease Process
32194247 ä. Exuberant Plasmocytosis in Bronchoalveolar Lavage Specimen of the First Patient Requiring Extracorporeal Membrane Oxygenation for SARS-CoV-2 in Europe
32114094 ä. Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer

32379723 2020. Molecular detection of SARS-CoV-2 in formalin fixed paraffin embedded specimens

32368701 ä. COVID-19?Associated Collapsing Glomerulopathy: An Emerging Entity
32327202 ä. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China
C7142700 ä. Collapsing Glomerulopathy in a Patient With Coronavirus Disease 2019 (COVID-19)
32346659 ä. Acute Kidney Injury Due to Collapsing Glomerulopathy Following COVID-19 Infection
32311318 ä. SARS-CoV-2 and viral sepsis: observations and hypotheses
32325026 2020. Endothelial cell infection and endotheliitis in COVID-19

32199493 ä. Viral dynamics in mild and severe cases of COVID-19
32330440 ä. Mediastinal lymphadenopathy in patients with severe COVID-19
32105638 ä. Viral load of SARS-CoV-2 in clinical samples
32085846 ä. Pathological findings of COVID-19 associated with acute respiratory distress syndrome
32341791 2020. Thoughts on COVID-19 and autoimmune diseases
32344305 ä. A data-driven hypothesis on the epigenetic dysregulation of host metabolism by SARS coronaviral infection: potential implications for the SARS-CoV-2 modus operandi

32243911 ä. C-reactive protein levels in the early stage of COVID-19
32291399 ä. Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies
32249846 ä. Dysregulation of lung myeloid cells in COVID-19

32216698 2020. Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility
32297540 2020. Association between platelet parameters and mortality in coronavirus disease 2019: Retrospective cohort study
32348339 2020. Correlation between Heart fatty acid binding protein and severe COVID-19: A case-control study
32298273 2020. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study

32326988 ä. Lactose Dehydrogenase in Patients with Severe COVID-19: A Meta-Analysis of Retrospective Study
32339247 ä. Does apolipoprotein E genotype predict COVID-19 severity?
32371949 2020. Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study

32283217 ä. Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings
32356025 ä. Early histologic findings of pulmonary SARS-CoV-2 infection detected in a surgical specimen
32350596 ä. The autopsy debate during the COVID-19 emergency: the Italian experience

32379417 ä. Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age

32379894 2020. Association between ABO blood groups and risk of SARS-CoV-2 pneumonia
32259373 2020. Cytologic and histologic samples from patients infected by the novel coronavirus 2019 SARS-CoV-2: An Italian institutional experience focusing on biosafety procedures
32346073 2020. COVID-19: towards understanding of pathogenesis

32294809 2020. Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis
32246845 2020. SARS?CoV?2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells
32353898 2020. Histopathology and genetic susceptibility in COVID-19 pneumonia
32367579 2020. The lysosome: A potential juncture between SARS-CoV-2 infectivity and Niemann-Pick disease type C, with therapeutic implications

32364407 2020. COVID-19 Lung Injury Is Different From High Altitude Pulmonary Edema (Re: High Alt Med Biol Epub ahead of print ; DOI: 10 1089/ham 2020 0055)
32281877 2020. COVID-19 Lung Injury is Not High Altitude Pulmonary Edema
32374419 2020. Pulmonary Pathology of Early Phase COVID-19 Pneumonia in a Patient with a Benign Lung Lesion

32198191 2020. Autopsy in suspected COVID-19 cases
32358895 2020. Histological pattern in Covid-19 induced viral rash

32369204 2020. Hepatic involvement in COVID-19 patients: Pathology, pathogenesis, and clinical implications
32294295 2020. Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19

32327758 2020. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

32273618 2020. How does COVID-19 kill? Uncertainty is hampering doctors ability to choose treatments

32339089 2020. Issues on Coronavirus Disease 2019 (COVID-19) Pathogenesis
32172546 2020. A pathological report of three COVID-19 cases by minimal invasive autopsies
32171194 2020. Pathological changes with novel coronavirus infection in lung cancer surgical specimen
32153166 2020. Provisional guidelines on autopsy practice for deaths associated with COVID-19
32268662 2020. Analysis of coronavirus disease-19 (COVID-19) based on SARS autopsy
32157847 2020. How to understand the histopathology of SARS and coronavirus disease-19 (COVID-19) associated with acute respiratory distress syndrome
32084674 2020. Detection of 2019-nCoV in the pathological paraffin embedded tissue
32340089 2020. Pathological changes of the spleen in ten patients with new coronavirus infection by minimally invasive autopsies
32114744 2020. Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases
32174095 2020. Advances in the research of mechanism of pulmonary fibrosis induced by Corona Virus Disease 2019 and the corresponding therapeutic measures

C7173822 2020. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study
32379077 2020. COVID-19: POSTMORTEM DIAGNOSTIC AND BIOSAFETY CONSIDERATIONS
32434133 2020. The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): Report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities

32427582 2020. Clinical and pathological investigation of severe COVID-19 patients.

32272221 ä. Host proteases as determinants of coronaviral neurotropism and virulence

32375845 2020. Acute respiratory failure in COVID-19: is it ?typical? ARDS?
32439197 ä. COVID-19 and Multiorgan Response
32362921 2020. Hypoxia in acute cardiac injury of coronavirus disease 2019: lesson learned from pathological studies
32340677 2020. Pulmonary Pathology of Early Phase 2019 Novel Coronavirus Pneumonia
32471641 ä. Tubuloreticular inclusions in COVID-19?related collapsing glomerulopathy
32471639 ä. Collapsing glomerulopathy in a COVID-19 patient
32292867 2020. Collapsing Glomerulopathy in a Patient With COVID-19
32459663 2020. COVID-19, microangiopathy, hemostatic activation, and complement.
32242089 ä. Endocrine and metabolic link to coronavirus infection
32382135 ä. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis
C7158196 2009. 64pp on topic review (+) Molecular Basis of Pulmonary Disease
C7197563 ä. Plasma Metabolomic and Lipidomic Alterations Associated with COVID-19
32454497 2020. COVID-19 and Nasal Cytobrush Cytology.
32437316 2020. Pathology and Pathogenesis of SARS-CoV-2 Associated with Fatal Coronavirus Disease, United States.
32412897 2020. Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan.
32484232 2020. Radiologisk och histologisk bild for en okad forstaelse vid covid-19.
32512290 2020. Expression of angiotensin-converting enzyme 2 and proteases in COVID-19 patients: A potential role of cellular FURIN in the pathogenesis of SARS-CoV-2.

32397896 2020. Placental Pathology in Covid-19 Positive Mothers: Preliminary Findings.

32485101 2020. Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak.
32423917 2020. COVID-19 as an Acute Inflammatory Disease.
32469258 2020. Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients.

32213267 2020. [Interpretation of pathological changes for "Guidelines for the Diagnosis and Treatment of COVID-19 by the National Health Commission (Trial Version 7) "].

32455515 2020. [Clinical feature changes of a COVID-19 patient from mild to critical condition and cardiopulmonary pathological results].

32486534 2020. [Pathological changes of fatal coronavirus disease 2019 (COVID-19) in the lungs: report of 10 cases by postmortem needle autopsy].
32433216 2020. Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Corona virus.

32507410 2020. The influenza virus, SARS-CoV-2, and the airways: Clarification for the otorhinolaryngologist.
32508022 2020. Acute lung injury in patients with COVID-19 infection.
32490934 2020. Ultrasound-guided minimally invasive autopsies: A protocol for the study of pulmonary and systemic involvement of COVID-19.
32443177 2020. Pulmonary and systemic involvement of COVID-19 assessed by ultrasound-guided minimally invasive autopsy.

32488957 2020. Procedures for Flow Cytometry-Based Sorting of Unfixed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Cells and Other Infectious Agents.
32468052 2020. Pancancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARSCoV2 infection leading to COVID-19.

32506059 2020. Detection of Hemosiderin-Laden Macrophages in Bronchoalveolar Lavage Fluid of COVID-19 Patients: Is Perls Stain a Potential Indicator of Oxidative Alveolar Damage?

32432483 2020. Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium.
32437622 2020. Complement Activation During Critical Illness: Current Findings and an Outlook in the Era of COVID-19.
32472588 2020. Increased sFLT1/PlGF ratio in COVID-19: a novel link to Angiotensin II-mediated endothelial dysfunction.
32491212 2020. Circulating endothelial cells in COVID-19.
32479159 2020. Related molecular mechanisms of COVID-19, hypertension, and diabetes.
32510978 2020. Overcoming Barriers: The Endothelium As a Linchpin of Coronavirus Disease 2019 Pathogenesis?
32441303 2020. Placental Pathology in COVID-19.
32451533 2020. Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases.
32420938 2020. What happens to people's lungs when they get coronavirus disease 2019?
32493030 2020. Thoughts on the alveolar phase of COVID-19.
32503680 2020. Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients.
32412156 2020. COVID-19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease.
32379368 2020. Gastrointestinal effects of an attempt to "disinfect" from COVID-19.

32422081 2020. Autopsy Report with Clinical Pathological Correlation.
32525657 2020. Proinflammatory Cytokines in the Olfactory Mucosa Result in COVID-19 Induced Anosmia.
32410724 2020. The Lungs before and after COVID-19 Pneumonia.
32459123 2020. Mechanistic inferences from clinical reports of SARS-CoV-2.
32406037 2020. COVID-19: is fibrosis the killer?
32415560 2020. Bronchoalveolar lavage findings in severe COVID-19 pneumonia.
32399954 2020. SARS-CoV-2 and myocardial injury: a role for Nox2?
32494927 2020. Histological-ultrasonographical correlation of pulmonary involvement in severe COVID-19.
32488341 2020. Rethinking the respiratory paradigm of COVID-19: a 'hole' in the argument.
32533198 2020. Pericyte alteration sheds light on micro-vasculopathy in COVID-19 infection.
32424481 2020. Stages or phenotypes? A critical look at COVID-19 pathophysiology.
32424480 2020. Contrast-enhanced ultrasound (CEUS) of the lung reveals multiple areas of microthrombi in a COVID-19 patient.
32504146 2020. Gross and histopathological pulmonary findings in a COVID-19 associated death during self-isolation.
32500199 2020. Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany.
32458044 2020. Inside the lungs of COVID-19 disease.
32451971 2020. Hyponatremia, IL-6, and SARS-CoV-2 (COVID-19) infection: may all fit together?
32434770 2020. Predictive molecular pathology in the time of COVID-19.
32497811 2020. Iron: Innocent bystander or vicious culprit in COVID-19 pathogenesis?
32522846 2020. ACE2 and COVID-19 and the resulting ARDS.
32473354 2020. Racial disparity in Covid-19 mortality rates - A plausible explanation.
32479986 2020. Type 3 hypersensitivity in COVID-19 vasculitis.
32437830 2020. SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19.
32462425 2020. High prevalence of antinuclear antibodies and lupus anticoagulant in patients hospitalized for SARS-CoV2 pneumonia.

host genetics

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