PHA SCR nsp10 nsp16 methyltransferase
(Die Seite wurde neu angelegt: „{{up|PHA pharmacophore by screened target}} {{plb|((covid19+OR+covid-19+OR+sars-cov2+OR+sars-cov-2+OR+2019-ncov+OR+2019ncov))+AND+(nsp10+OR+non-structural+prot…“) |
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{{plb|((covid19+OR+covid-19+OR+sars-cov2+OR+sars-cov-2+OR+2019-ncov+OR+2019ncov))+AND+(nsp10+OR+non-structural+protein+10+OR+nsp16+OR+non-structural+protein+16+OR+methyltransferase))|nsp10,16 methyltransferase}} | {{plb|((covid19+OR+covid-19+OR+sars-cov2+OR+sars-cov-2+OR+2019-ncov+OR+2019ncov))+AND+(nsp10+OR+non-structural+protein+10+OR+nsp16+OR+non-structural+protein+16+OR+methyltransferase))|nsp10,16 methyltransferase}} | ||
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| + | "nonstructural protein 16 (nsp16) of coronavirus is an S-adenosyl methionine (SAM)-dependent 2'-O-methyltransferase (2'-O-MTase) that has an important role in viral replication and prevents recognition by the host innate immune system" 32835632 | ||
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{{tp|p=32741322|t=2020. Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study.|pdf=|usr=017}} | {{tp|p=32741322|t=2020. Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study.|pdf=|usr=017}} | ||
{{tp|p=32835632|t=2020. In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2.|pdf=|usr=018}} | {{tp|p=32835632|t=2020. In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2.|pdf=|usr=018}} | ||
Aktuelle Version vom 21. April 2021, 20:09 Uhr
| PHA pharmacophore by screened target |
| living current stringent pubmed readout on nsp10,16 methyltransferase |
"nonstructural protein 16 (nsp16) of coronavirus is an S-adenosyl methionine (SAM)-dependent 2'-O-methyltransferase (2'-O-MTase) that has an important role in viral replication and prevents recognition by the host innate immune system" 32835632
32741322 2020. Identification of promising drug candidates against NSP16 of SARS-CoV-2 through computational drug repurposing study.
32835632 2020. In silico validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2.
33252031 2020. Identification of naphthyridine and quinoline derivatives as potential Nsp16-Nsp10 inhibitors: a pharmacoinformatics study.
32738360 2020. Computational guided drug repurposing for targeting 2'-O-ribose methyltransferase of SARS-CoV-2.
33016237 2020. Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus.
