Candidate Compounds Covid19

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...so calm down and enjoy the progress of immediate translational medicine:
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A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
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This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
 +
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
 +
Paper is (not yet in PubMed) :
  
current items will be put into the subsections.
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*'''[https://www.sciencedirect.com/science/article/pii/S1097276520305499?via%3Dihub Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication at Mol Cell 2020/08/11]'''
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credentials to [https://web.de/magazine/news/coronavirus/coronavirus-blockade-zellulaerer-kommunikation-forscher-stoppen-vermehrung-sars-cov-2-35045170 Marinus Brandl] who told us about it today.
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based on e.g.
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{{ttp|p=32408336|t=2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets |pdf=|usr=}}
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=======================================================================================
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COVID19 is now a CURABLE disease !!!
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=======================================================================================
  
 
*[[reviews on covid drug development]]  
 
*[[reviews on covid drug development]]  
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*[[Target Complement system]]
 
*[[Target Complement system]]
 
*[[Target Extracellular traps]]
 
*[[Target Extracellular traps]]
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*[[Caplacizumab]] vWF(TTP)
 
*[[Target Neurophils]]
 
*[[Target Neurophils]]
 
*[[Target Mast cells]] and kinins
 
*[[Target Mast cells]] and kinins
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*[[Target ACE2, Spike protein]]
 
*[[Target ACE2, Spike protein]]
 
*[[Target TMPRSS2, Spike protein]] ''any other covid targed herein''
 
*[[Target TMPRSS2, Spike protein]] ''any other covid targed herein''
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*[[Aprotinin]] protease inh bradykinin synth. inh.
 
*[[other antiviral compounds]]
 
*[[other antiviral compounds]]
 
*[[AV Remdesivir]]
 
*[[AV Remdesivir]]
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*[[Treatment other concepts]]
 
*[[Treatment other concepts]]
 
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{{tp|p=32417594|t=2020. Supplements for COVID-19: A modifiable environmental risk.|pdf=|usr=011}}
 

Version vom 3. Oktober 2020, 20:18 Uhr

coviki.org collects the really good Ideas and the scientific Record on Covid-19 Virus.

 P further streaming-in related content is here

...so calm down and enjoy the progress of immediate translational medicine:

A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
Paper is (not yet in PubMed) :

credentials to Marinus Brandl who told us about it today. based on e.g.

32408336 2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
=======================================================================================
COVID19 is now a CURABLE disease !!!
=======================================================================================





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