Candidate Compounds Covid19

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A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
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*'''[[scouting ideas]]'''
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
+
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
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Paper is (not yet in PubMed) :
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*'''[https://www.sciencedirect.com/science/article/pii/S1097276520305499?via%3Dihub Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication at Mol Cell 2020/08/11]'''
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*'''[[PHA Biologicals]]'''
credentials to [https://web.de/magazine/news/coronavirus/coronavirus-blockade-zellulaerer-kommunikation-forscher-stoppen-vermehrung-sars-cov-2-35045170 Marinus Brandl] who told us about it today.
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based on e.g.
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{{ttp|p=32408336|t=2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets |pdf=|usr=}}
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*'''[[PHA conventional pharmacology]]'''
  
=======================================================================================
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*'''[[PHA retargeted compounds]]'''
  
COVID19 is now a CURABLE disease !!!
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*'''[[PHA antivirals by mechanism]]'''
  
=======================================================================================
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*'''[[PHA pharmacophore by screened target]]'''
  
*[[reviews on covid drug development]]
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*'''[[PHA ImmunoNutrients]]
*[[scouting ideas]]
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*[[Patients on biologicals]]
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*'''[[PHA compl altern natural]]'''
*[[HMGB1, RAGE]]
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*[[pre-Interleukin 6]]
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*[[post-Interleukin 6]]
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*[[pre-TNFalpha]]
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*[[post-TNFalpha]]
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*[[pre-Interleukin 17]]
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*[[post-Interleukin 17]]
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*[[pre-Interleukin 1]]
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*[[post-Interleukin 1]]
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*[[Inflammasome]] ''colchicine''
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*[[Methotrexate]]
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*[[other anti-inflammatory]]
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*[[NK-kappaB]]
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*[[STAT 3]]
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*[[JAK Janus Kinase]]
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*[[Corticosteroids]]
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*[[Cytokine absorbers]]
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*[[Target Complement system]]
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*[[Target Extracellular traps]]
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*[[Caplacizumab]] vWF(TTP)
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*[[Target Neurophils]]
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*[[Target Mast cells]] and kinins
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*[[TGF beta]]
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*[[Immunosuppressants]]
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*[[Anticoagulant in covid19]]
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*[[Antioxidants]]
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*[[HIF-EPO-Iron]]
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*[[Stem cells]]
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*[[MDSC cells]]
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*[[Interferons]]
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*[[cAMP cGMP PDE NO]]
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*[[TRPV* channels]]
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*[[Retinoids]]
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*[[Protease inhibitors]]
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*[[Tyrosine kinase inhibitors]]
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*[[Antineoplastic agents, traditional]]
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*[[Mouthrinses]]
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*[[Adenosinergic signaling]]
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*[[Purinergic signaling]]
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*[[Nicotinergic signaling]]
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 +
*'''[[PHA within indications compounds]]'''
  
*[[other single compounds]]
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*'''[[PHA Serum products]]'''
*[[Retargeted Psychopharm]]
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*[[Hydroxychloroquine]]
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*
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*[[Target ACE2, Spike protein]]
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*[[Target TMPRSS2, Spike protein]] ''any other covid targed herein''
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*[[Aprotinin]] protease inh bradykinin synth. inh.
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*[[other antiviral compounds]]
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*[[AV Remdesivir]]
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*[[AV Lopinavir]]
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*'''[[AV Ivermectin]]'''
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*[[AV Arabidol]]
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*[[AV Favipiravir]]
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*[[AV Molnupiravir]]
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*[[Antibiotics]]
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*'''[[PHA Vaccination]]'''
  
 +
PHA related options:
  
*[[Vitamin D]]
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*[[Radiation therapy]]
*[[Anorganic nutrients Magnesium]]
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*[[Phototherapy]]
*[[Anorganic nutrients Selenium]]
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*[[Electric fields]]
*[[Anorganic nutrients Zinc]]
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*[[Treatment other concepts]]
*[[Anorganic nutrients Lithium]]
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*[[Anorganic nutrients Copper]]
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*[[Anorganic nutrients Bismuth]]
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*[[Nutrition, general]]
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*[[Exercise, Vibration]]
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*[[Traditional Chinese Medicine]]
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A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
*[[Natural compounds]]
+
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
 +
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
 +
Paper is (not yet in PubMed) :
  
*[[Statins]]
+
*'''[https://www.sciencedirect.com/science/article/pii/S1097276520305499?via%3Dihub Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication at Mol Cell 2020/08/11]'''
*[[Antidiabetic compounds, any]]
+
credentials to [https://web.de/magazine/news/coronavirus/coronavirus-blockade-zellulaerer-kommunikation-forscher-stoppen-vermehrung-sars-cov-2-35045170 Marinus Brandl] who told us about it today.
*[[RSP - On RAS drugs]]
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based on e.g.
*[[RSP - On NSAIDs]]
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*[[Reconvalescent blood products, Passive vaccine]]
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{{ttp|p=32408336|t=2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets |pdf=|usr=}}
*[[Plasmapheresis]]
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*[[Immunodeviation]] e.g. by adjuvants or other vaccinations
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=======================================================================================
*[[Radiation therapy]]
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*[[Phototherapy]]
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*[[Active vaccine]]
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*[[Treatment other concepts]]
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COVID19 is now a CURABLE disease !!!
----
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 +
=======================================================================================

Aktuelle Version vom 21. September 2021, 06:15 Uhr

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Reviews on covid drug development


PHA related options:


A concept of curative retargeting has been found by cellular lockdown with kinase inhibitors from the oncologic pharmacopoiea.
This means, virus replication can be stalled to zero w/o need of develpoment of new substances. There is no need for world
vaccination anymore. The virus needs permissible cells, and most perimissible is phosphotyrosine on its own compnents.
Paper is (not yet in PubMed) :

credentials to Marinus Brandl who told us about it today. based on e.g.

32408336 2020. Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
=======================================================================================
COVID19 is now a CURABLE disease !!!
=======================================================================================

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